Michael Wilhelm


Affiliation: Columbia University
Country: USA


  1. Wilhelm M, Xu Z, Kukekov N, Gire S, Greene L. Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. J Biol Chem. 2007;282:1288-95 pubmed
    ..These results indicate that Nix promotes cell death via interaction with POSH and activation of the JNK/c-Jun pathway and that Nix protein is induced and contributes to cell death in a cellular model of Parkinson disease. ..
  2. Wilhelm M, Kukekov N, Xu Z, Greene L. Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. Dev Neurosci. 2007;29:355-62 pubmed
    ..These results indicate that POSH2 may regulate JNK activation and consequent apoptosis under conditions of increased expression. ..