Research Topics
| ROBIN MARJORIE WHYATTSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of ageRobin M Whyatt
Department of Environmental Health Sciences, Columbia Center for Children s Environmental Health Department of Environmental Health Sciences, Mailman School of Public Health, 722 West 168th St, New York, NY 10032 USA
Environ Health Perspect 120:290-5. 2012..Research suggests that prenatal phthalate exposures affect child executive function and behavior...
Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic researchJennifer J Adibi
Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
Environ Health 8:20. 2009..We report on methodologic challenges to be considered in study design...
Prenatal di(2-ethylhexyl)phthalate exposure and length of gestation among an inner-city cohortRobin M Whyatt
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Pediatrics 124:e1213-20. 2009..Our objective was to assess the relationship between di(2-ethylhexyl)phthalate (DEHP) exposure during pregnancy and gestational age at delivery among 311 African American or Dominican women from New York City...
A biomarker validation study of prenatal chlorpyrifos exposure within an inner-city cohort during pregnancyRobin M Whyatt
Columbia Center for Children s Environmental Health, Department of Environmental Health Sciences, Joseph L Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 117:559-67. 2009....
Within- and between-home variability in indoor-air insecticide levels during pregnancy among an inner-city cohort from New York CityRobin M Whyatt
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 115:383-9. 2007..Residential insecticide use is widespread in the United States, but few data are available on the persistence and variability in levels in the indoor environment...
Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure: a validation studyR M Whyatt
Columbia Center for Children s Environmental Health, Division of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 109:417-20. 2001..Further research is needed to determine the time frame of exposure represented by pesticide levels in meconium and to evaluate the dose-response relationship...
Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growthR M Whyatt
Columbia Center for Children s Environmental Health, Department of Environmental Health Sciences, Joseph L Mailman School of Public Health, Columbia University, 60 Haven Ave, B 1, New York, NY 10032, USA
Toxicol Appl Pharmacol 206:246-54. 2005..No association was seen between birth weight and length and cord plasma chlorpyrifos or diazinon among newborns born after 1/1/01 (P > 0.8). Results support recent regulatory action to phase out residential uses of these insecticides...
Prenatal insecticide exposures and birth weight and length among an urban minority cohortRobin M Whyatt
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 112:1125-32. 2004..Findings support recent regulatory action to phase out residential uses of the insecticides...
Biomarkers of polycyclic aromatic hydrocarbon-DNA damage and cigarette smoke exposures in paired maternal and newborn blood samples as a measure of differential susceptibilityR M Whyatt
Division of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Cancer Epidemiol Biomarkers Prev 10:581-8. 2001..The results have implications for risk assessment, which currently does not adequately account for sensitive subsets of the population...
Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newbornsRobin M Whyatt
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 111:749-56. 2003..Findings indicate that pesticide exposures are frequent but decreasing and that the pesticides are readily transferred to the developing fetus during pregnancy...
An intervention to reduce residential insecticide exposure during pregnancy among an inner-city cohortMegan K Williams
Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 114:1684-9. 2006..These pilot data suggest that IPM is an effective strategy for reducing pest infestation levels and the internal dose of insecticides during pregnancy...
Prenatal exposures to phthalates among women in New York City and Krakow, PolandJennifer J Adibi
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 111:1719-22. 2003..01), and BBzP and monobenzyl phthalate (r = 0.65, p < 0.01). These results demonstrate considerable phthalate exposures during pregnancy among women in these two cohorts and indicate that inhalation is an important route of exposure...
Residential pesticide use during pregnancy among a cohort of urban minority womenRobin M Whyatt
Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 110:507-14. 2002..Diazinon exposures for some women may have exceeded health-based levels, and our findings support recent federal action to phase out residential use of this insecticide...
Predictors of personal polycyclic aromatic hydrocarbon exposures among pregnant minority women in New York CityCathryn C Tonne
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 112:754-9. 2004..This is the largest study to date characterizing personal exposures to PAHs, a ubiquitous class of carcinogenic air contaminants in urban environments, and is unique in its focus on pregnant minority women...
International studies of prenatal exposure to polycyclic aromatic hydrocarbons and fetal growthHyunok Choi
Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 114:1744-50. 2006..Fetal growth impairment has been linked to child developmental and health problems. Thus, substantial health benefits would result from global reduction of PAH emissions...
Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphatesMegan K Williams
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Avenue, New York, NY 10032, USA
Environ Health Perspect 116:1681-8. 2008..The mix of active pesticide ingredients is changing in response to 2000-2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon...
The challenge of preventing environmentally related disease in young children: community-based research in New York CityFrederica P Perera
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Avenue, New York, NY 10032, USA
Environ Health Perspect 110:197-204. 2002..In turn, communities become better equipped to relay environmental health concerns to policy makers. In this paper we describe the center's research and its academic-community partnership and present some preliminary findings...
Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner-city childrenFrederica P Perera
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 114:1287-92. 2006..The results require confirmation but suggest that environmental PAHs at levels recently encountered in New York City air may adversely affect children's cognitive development at 3 years of age, with implications for school performance...
Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic populationFrederica P Perera
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Environ Health Perspect 111:201-5. 2003..This study provides evidence that environmental pollutants at levels currently encountered in New York City adversely affect fetal development...
Polycyclic aromatic hydrocarbon metabolite levels and pediatric allergy and asthma in an inner-city cohortRachel L Miller
Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, New York, NY 10032, USA
Pediatr Allergy Immunol 21:260-7. 2010..Levels of PAH metabolites were not associated with respiratory symptoms. Measures of PAH metabolites suggest considerable exposure in an urban pediatric population, and possible associations with allergic sensitization to mouse...
Urinary and air phthalate concentrations and self-reported use of personal care products among minority pregnant women in New York cityAllan C Just
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Expo Sci Environ Epidemiol 20:625-33. 2010..05), but was not associated with perfume use. Air DEP was correlated with urine MEP concentrations only among non-perfume users (r=0.51, P<0.001). Results suggest that perfume use is a significant source of DEP exposure...
Impact of prenatal exposure to piperonyl butoxide and permethrin on 36-month neurodevelopmentMegan K Horton
Sergievsky Center, New York, NY, USA
Pediatrics 127:e699-706. 2011..Our objective was to explore the association between prenatal exposure to permethrin (a common pyrethroid) and piperonyl butoxide (a pyrethroid synergist) and 36-month neurodevelopment...
Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohortRachel L Miller
Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, PH8C, 630 168th Street, New York, NY 10032, USA
Chest 126:1071-8. 2004....
Biomarkers in maternal and newborn blood indicate heightened fetal susceptibility to procarcinogenic DNA damageFrederica P Perera
Mailman School of Public Health of Columbia University, Department of Environmental Health Sciences, New York, New York 10032, USA
Environ Health Perspect 112:1133-6. 2004..The findings have implications for risk assessment, given the need to protect children as a sensitive subset of the population...
Molecular evidence of an interaction between prenatal environmental exposures and birth outcomes in a multiethnic populationFrederica P Perera
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Avenue B 109, New York, NY 10032, USA
Environ Health Perspect 112:626-30. 2004..This study provides evidence that combined exposure to environmental pollutants at levels currently encountered in New York City adversely affects fetal development...
Risk for asthma in 1-year-old infants residing in New York City high-risk neighborhoodsIlan H Meyer
Mailman School of Public Health, Columbia University, Columbia Center for Children's Environmental Health, New York, New York 10032, USA
J Asthma 40:545-50. 2003
The common insecticides cyfluthrin and chlorpyrifos alter the expression of a subset of genes with diverse functions in primary human astrocytesSarah M Mense
Department of Environmental Health Sciences, Columbia University, Mailman School of Public Health, New York, New York 10032, USA
Toxicol Sci 93:125-35. 2006..These results suggest that inflammatory activation of astrocytes might be an important mechanism underlying neurotoxicity of both chlorpyrifos and cyfluthrin...
Exposure assessment implications for the design and implementation of the National Children's StudyHaluk Ozkaynak
U S Environmental Protection Agency, National Exposure Research Laboratory, Research Triangle Park, North Carolina 27711, USA
Environ Health Perspect 113:1108-15. 2005..e., ranging from simple to more complex) derived from the detailed validation subsamples...
Effect of prenatal PAH exposure on birth outcomes and neurocognitive development in a cohort of newborns in Poland. Study design and preliminary ambient dataWiesław Jedrychowski
Department of Epidemiology and Preventive Medicine, Collegium Medicum, Jagiellonian University, Krakow, Poland
Int J Occup Med Environ Health 16:21-9. 2003..Auto emissions for example, are low in benzo(a)pyrene, whereas such emissions from refuse burning are high...
Exposure assessment in the National Children's Study: introductionLarry L Needham
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Environ Health Perspect 113:1076-82. 2005..Criteria for the analytical method of choice are discussed with particular emphasis on the need for long-term quality control and quality assurance measures...
Characterizing exposures to nonpersistent pesticides during pregnancy and early childhood in the National Children's Study: a review of monitoring and measurement methodologiesAsa Bradman
Center for Children's Environmental Health Research, School of Public Health, University of California, Berkeley, California, USA
Environ Health Perspect 113:1092-9. 2005....
Variability of total exposure to PM2.5 related to indoor and outdoor pollution sources Krakow study in pregnant womenWieslaw A Jedrychowski
Chair of Epidemiology and Preventive Medicine, Medical College, Jagiellonian University, 7A, Kopernika St, 31 034 Krakow, Poland
Sci Total Environ 366:47-54. 2006....
Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention ResearchBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California, USA
Environ Health Perspect 113:1419-29. 2005..These centers present barriers encountered, solutions found, and considerations for future research, with the hope that the lessons learned can help inform the planning and conduct of the National Children's Study...
Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studiesRichard A Fenske
Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
Environ Health Perspect 113:1455-62. 2005..Saliva measurements of pesticides, if feasible, would overcome the limitations of urinary metabolite-based exposure analysis. Global positioning system technology appears promising in the delineation of children's time-location patterns...
Meeting report: measuring endocrine-sensitive endpoints within the first years of lifeTye E Arbuckle
Biostatistics and Epidemiology Division, Health Canada, Ottawa, Ontario, Canada
Environ Health Perspect 116:948-51. 2008....
A multi-analyte method for the quantification of contemporary pesticides in human serum and plasma using high-resolution mass spectrometryDana B Barr
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mailstop F17, Atlanta, GA 30341, USA
J Chromatogr B Analyt Technol Biomed Life Sci 778:99-111. 2002..We found detectable concentrations of carbaryl/naphthalene, propoxur, bendiocarb, chlorpyrifos, diazinon, dicloran, captan and folpet or their metabolites in more than 20% of the plasma samples tested...
Research Grants
- Phthalate Exposure and Inner City Pediatric AsthmaRobin Whyatt; Fiscal Year: 2009..abstract_text> ..
- Phthalate Exposure and Inner City Pediatric AsthmaROBIN MARJORIE WHYATT; Fiscal Year: 2010....
- Phthalate Exposure and Inner City Pediatric AsthmaRobin Whyatt; Fiscal Year: 2009....
- Prenatal Phthalates, Placenta Function and Fetal GrowthRobin Whyatt; Fiscal Year: 2007..abstract_text> ..
- Phthalate Exposure and Inner City Pediatric AsthmaRobin Whyatt; Fiscal Year: 2007....
- Prenatal Insecticide Exposures Among Urban MinoritiesRobin Whyatt; Fiscal Year: 2005..The research will provide important information about pesticide exposure during pregnancy among this minority cohort. ..
- Validation of biomarkers of prenatal pesticides exposureRobin Whyatt; Fiscal Year: 2003....
- Early-life phthalate exposure, thyroid function and child cognitive developmentROBIN MARJORIE WHYATT; Fiscal Year: 2010....
