MYRNA M contact WEISSMAN

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Interstitial cystitis and panic disorder: a potential genetic syndrome
    Myrna M Weissman
    Departments of Psychiatry and Urology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 61:273-9. 2004
  2. ncbi request reprint Offspring of depressed parents: 20 years later
    Myrna M Weissman
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, Unit 24, 1051 Riverside Dr, New York, NY 10032, USA
    Am J Psychiatry 163:1001-8. 2006
  3. pmc Genotyping serotonin transporter polymorphisms 5-HTTLPR and rs25531 in European- and African-American subjects from the National Institute of Mental Health's Collaborative Center for Genomic Studies
    Z Odgerel
    1 Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA 2 Division of Epidemiology, New York State Psychiatric Institute, New York, NY, USA
    Transl Psychiatry 3:e307. 2013
  4. pmc Interpersonal psychotherapy: evaluation, support, triage
    Myrna Weissman
    College of Physicians and Surgeons, Columbia University, New York, USA
    Clin Psychol Psychother 19:106-12. 2012
  5. ncbi request reprint Recent non-medication trials of interpersonal psychotherapy for depression
    Myrna M Weissman
    College of Physicians and Surgeons, Columbia University, and Department of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY 10034, USA
    Int J Neuropsychopharmacol 10:117-22. 2007
  6. pmc Gender differences in posttraumatic stress disorder among primary care patients after the World Trade Center attack of September 11, 2001
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Gend Med 2:76-87. 2005
  7. ncbi request reprint Families at high and low risk for depression: a 3-generation study
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 62:29-36. 2005
  8. ncbi request reprint Depressed mothers coming to primary care: maternal reports of problems with their children
    Myrna M Weissman
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY, USA
    J Affect Disord 78:93-100. 2004
  9. ncbi request reprint Children with prepubertal-onset major depressive disorder and anxiety grown up
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 56:794-801. 1999
  10. ncbi request reprint What research suggests for depressed women with children
    Myrna M Weissman
    College of Physicians and Surgeons, Joseph Mailman School of Public Health, Columbia University, USA
    J Clin Psychiatry 63:641-7. 2002

Research Grants

  1. GENETIC STUDIES OF DEPRESSIVE DISORDERS
    Myrna Weissman; Fiscal Year: 2003
  2. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    MYRNA M contact WEISSMAN; Fiscal Year: 2010
  3. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2006
  4. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2002
  5. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2002
  6. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2002
  7. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2007
  8. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2003
  9. Parental Remission from Depression and Child Psychopathology
    Myrna Weissman; Fiscal Year: 2009
  10. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2003

Detail Information

Publications99

  1. ncbi request reprint Interstitial cystitis and panic disorder: a potential genetic syndrome
    Myrna M Weissman
    Departments of Psychiatry and Urology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 61:273-9. 2004
    ..Whereas PD had been well characterized by direct interview, the urologic problems had been found only via medical history checklists and records. A case review by a board-certified urologist suggested they could be IC...
  2. ncbi request reprint Offspring of depressed parents: 20 years later
    Myrna M Weissman
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, Unit 24, 1051 Riverside Dr, New York, NY 10032, USA
    Am J Psychiatry 163:1001-8. 2006
    ..This study was a 20-year follow-up of offspring of depressed and nondepressed parents to determine the magnitude and continuity of the risk of parental depression to the offspring...
  3. pmc Genotyping serotonin transporter polymorphisms 5-HTTLPR and rs25531 in European- and African-American subjects from the National Institute of Mental Health's Collaborative Center for Genomic Studies
    Z Odgerel
    1 Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA 2 Division of Epidemiology, New York State Psychiatric Institute, New York, NY, USA
    Transl Psychiatry 3:e307. 2013
    ..This is the largest study to show SLC6A4 genotype differences between EA and AA populations, and the first to include rs25531. Lack of associations with clinical outcomes may reflect untested moderating environmental influences. ..
  4. pmc Interpersonal psychotherapy: evaluation, support, triage
    Myrna Weissman
    College of Physicians and Surgeons, Columbia University, New York, USA
    Clin Psychol Psychother 19:106-12. 2012
    ....
  5. ncbi request reprint Recent non-medication trials of interpersonal psychotherapy for depression
    Myrna M Weissman
    College of Physicians and Surgeons, Columbia University, and Department of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY 10034, USA
    Int J Neuropsychopharmacol 10:117-22. 2007
    ..Until the gap between training in psychotherapy and the research evidence in psychotherapy is bridged in training programmes, it will be difficult to provide patients with these treatments...
  6. pmc Gender differences in posttraumatic stress disorder among primary care patients after the World Trade Center attack of September 11, 2001
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Gend Med 2:76-87. 2005
    ..Debate surrounds the nature of gender differences in rates of posttraumatic stress disorder (PTSD)...
  7. ncbi request reprint Families at high and low risk for depression: a 3-generation study
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 62:29-36. 2005
    ..The first 2 generations were interviewed 4 times during this period. The offspring from the second generation are now adults and have children of their own, the third generation of the original cohort...
  8. ncbi request reprint Depressed mothers coming to primary care: maternal reports of problems with their children
    Myrna M Weissman
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY, USA
    J Affect Disord 78:93-100. 2004
    ..Data on the relationship between maternal depression and problems in the offspring in a primary care context could help physicians to more effectively identify children in need of psychiatric help...
  9. ncbi request reprint Children with prepubertal-onset major depressive disorder and anxiety grown up
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 56:794-801. 1999
    ..The continuity in adulthood of major depressive disorder (MDD) first arising before puberty is largely unknown. This information could guide early treatment and clarify the appropriateness of including children with MDD in genetic studies...
  10. ncbi request reprint What research suggests for depressed women with children
    Myrna M Weissman
    College of Physicians and Surgeons, Joseph Mailman School of Public Health, Columbia University, USA
    J Clin Psychiatry 63:641-7. 2002
    ..The strong association between maternal and offspring depression has been observed in numerous studies. Understanding this association has implications for early intervention and prevention...
  11. ncbi request reprint Juvenile-onset major depression includes childhood- and adolescent-onset depression and may be heterogeneous
    Myrna M Weissman
    Division of Clinical and Genetic Epidemiology, College of Physicians and Surgeons of Columbia University and the New York State Psychiatric Institute, 1051 Riverside Dr, Unit 24, New York, NY 10032, USA
    Arch Gen Psychiatry 59:223-4. 2002
  12. ncbi request reprint Remissions in maternal depression and child psychopathology: a STAR*D-child report
    Myrna M Weissman
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York 10032, USA
    JAMA 295:1389-98. 2006
    ..Children of depressed parents have high rates of anxiety, disruptive, and depressive disorders that begin early, often continue into adulthood, and are impairing...
  13. ncbi request reprint Recent advances in depression across the generations
    Myrna M Weissman
    College of Physicians and Surgeons, Columbia University, Department of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 24, New York, NY 10034, USA
    Epidemiol Psichiatr Soc 15:16-9. 2006
    ..New opportunities for early detection and treatment exist. Families with three generations affected with depression present a potentially important group for biological, genetic and neuroimaging studies...
  14. ncbi request reprint National survey of psychotherapy training in psychiatry, psychology, and social work
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, New York, New York 10032, USA
    Arch Gen Psychiatry 63:925-34. 2006
    ..Few practitioners use EBT...
  15. pmc A comparison between screened NIMH and clinically interviewed control samples on neuroticism and extraversion
    A Talati
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 13:122-30. 2008
    ....
  16. pmc Translational epidemiology in psychiatry: linking population to clinical and basic sciences
    Myrna M Weissman
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Gen Psychiatry 68:600-8. 2011
    ..The approach described has implications for providing fresh metaphors to communicate complex issues in interdisciplinary collaborations and for training in epidemiology and other sciences in psychiatry...
  17. pmc Positive screens for psychiatric disorders in primary care: a long-term follow-up of patients who were not in treatment
    Myrna M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Psychiatr Serv 61:151-9. 2010
    ..The purpose of this study was to determine the clinical utility of screening by conducting a long-term follow-up of patients who screened positive for psychiatric disorders but who were initially not in treatment...
  18. pmc Depression
    Myrna Weissman
    Department of Psychiatry, College of Physicians and Surgeons and Mailman School of Public Health, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Ann Epidemiol 19:264-7. 2009
    ..I hope the new generation will have the wonderful opportunities I have had...
  19. ncbi request reprint Ethnic and sex differences in suicide rates relative to major depression in the United States
    M A Oquendo
    Conte Center for the Neuroscience of Mental Disorders, New York State Psychiatric Institute, New York NY 10032, USA
    Am J Psychiatry 158:1652-8. 2001
    ..Some possibilities are that depression differs in form or severity or that unidentified factors protect against suicide in different subgroups...
  20. ncbi request reprint Suicidal ideation in primary care
    M Olfson
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    J Gen Intern Med 11:447-53. 1996
    ..CONCLUSIONS: In these primary care patients, suicidal ideation is strongly associated with mental disorder and mental health-related functional impairment, and can be detected with a single self-report "feeling suicidal" item...
  21. pmc The role of fear and anxiety in the familial risk for major depression: a three-generation study
    V Warner
    Division of Epidemiology, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Psychol Med 38:1543-56. 2008
    ..This study, using a longitudinal high-risk design, examined whether anxiety disorders associated with the emotions fear and anxiety mediate the association between parental and offspring depression...
  22. ncbi request reprint Depressed adolescents grown up
    M M Weissman
    Division of Clinical and Genetic Epidemiology, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, New York 10032, USA
    JAMA 281:1707-13. 1999
    ..Major depressive disorder (MDD) that arises in adolescence impairs functioning and is associated with suicide risk, but little is known about its continuity into adulthood...
  23. ncbi request reprint Panic and suicidal ideation in primary care
    R Goodwin
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, and The Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Depress Anxiety 14:244-6. 2001
    ..4) or panic attacks (OR = 7.9). There is need for detection and possible treatment of patients with panic attacks or disorder in primary care, especially among those with co-occurring major depression...
  24. ncbi request reprint Rates of lifetime suicide attempt and rates of lifetime major depression in different ethnic groups in the United States
    M A Oquendo
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Acta Psychiatr Scand 110:446-51. 2004
    ..Rates of major depression and suicide vary across ethnic groups within the US. This also may be true of suicide attempts...
  25. ncbi request reprint Phenotype definitions: some hidden issues in psychiatry
    M M Weissman
    Division of Clinical and Genetic Epidemiology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Am J Med Genet 105:45-7. 2001
    ....
  26. ncbi request reprint A comparison of three scales for assessing social functioning in primary care
    M M Weissman
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, NY 10032, USA
    Am J Psychiatry 158:460-6. 2001
    ..Although several scales for assessing functioning are widely used, they vary in coverage, and direct comparisons among them are rare. Comparative information is useful in guiding selection of appropriate scales for research applications...
  27. ncbi request reprint Brief screening for family psychiatric history: the family history screen
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, New York 10032, USA
    Arch Gen Psychiatry 57:675-82. 2000
    ..Brief screens to collect lifetime family psychiatric history are useful in clinical practice and for identifying potential families for genetic studies...
  28. ncbi request reprint Social functioning and the treatment of depression
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychiatry 61:33-8. 2000
    ....
  29. ncbi request reprint The cross-national epidemiology of panic disorder
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York 10032, USA
    Arch Gen Psychiatry 54:305-9. 1997
    ..Epidemiological data on panic disorder from community studies from 10 countries around the world are presented to determine the consistency of findings across diverse cultures...
  30. ncbi request reprint Psychiatric disorders in the relatives of probands with prepubertal-onset or adolescent-onset major depression
    P J Wickramaratne
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 39:1396-405. 2000
    ..To determine whether the familial risk of major depressive disorder (MDD) varies with either onset, recurrence, or continuity of MDD in adulthood in prepubertal- compared with adolescent-onset probands...
  31. ncbi request reprint Screening for depression in mothers bringing their offspring for evaluation or treatment of depression
    T Ferro
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Am J Psychiatry 157:375-9. 2000
    ..However, little is known about rates of current depression in mothers who bring their offspring to outpatient clinics for evaluation and/or treatment of depression. This information might be useful in developing intervention strategies...
  32. ncbi request reprint Potential panic disorder syndrome: clinical and genetic linkage evidence
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University, New York, New York, USA
    Am J Med Genet 96:24-35. 2000
    ..Am. J. Med. Genet.(Neuropsychiatr. Genet.) 96:24-35, 2000...
  33. ncbi request reprint Grandparents, parents, and grandchildren at high risk for depression: a three-generation study
    V Warner
    Division of Clinical Genetic Epidemiology, New York State Psychiatric Institute, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 38:289-96. 1999
    ..Using a high-risk design, this study examines the association of grandparent major depressive disorder (MDD) and parent MDD with psychopathology in grandchildren...
  34. ncbi request reprint The NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study: background and methodology
    B B Lahey
    Department of Psychiatry, University of Chicago, IL 60637, USA
    J Am Acad Child Adolesc Psychiatry 35:855-64. 1996
    ..A collaborative study was conducted to develop methods for surveys of mental disorder and service utilization in unscreened population-based samples of children and adolescents...
  35. ncbi request reprint Cross-national epidemiology of major depression and bipolar disorder
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA
    JAMA 276:293-9. 1996
    ..To estimate the rates and patterns of major depression and bipolar disorder based on cross-national epidemiologic surveys...
  36. ncbi request reprint Medically unexplained symptoms in an urban general medicine practice
    A Feder
    Department of Psychiatry, College of Physicians and Surgeons, New York, NY, USA
    Psychosomatics 42:261-8. 2001
    ..These data suggest that patients with MMUS are as common in urban primary care clinics as in more affluent clinics and reinforce the need for PCPs to screen these patients for common and treatable psychiatric conditions...
  37. ncbi request reprint Psychopathology in children of parents with opiate dependence and/or major depression
    E V Nunes
    Department of Genetic Epidemiology, New York State Psychiatric Institute, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 37:1142-51. 1998
    ..To evaluate psychiatric disorders and impairment in school-age and adolescent children of opiate-dependent patients...
  38. ncbi request reprint Offspring of depressed parents. 10 Years later
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Arch Gen Psychiatry 54:932-40. 1997
    ..None have followed up the offspring into adulthood to obtain more precise estimates of risk...
  39. ncbi request reprint Results of a genome-wide genetic screen for panic disorder
    J A Knowles
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Am J Med Genet 81:139-47. 1998
    ..Analysis with SIBPAIR yielded P values equivalent to a lod score of 1.0 or greater (i.e., P < .016, one-sided, uncorrected for multiple tests) for 11 marker loci (2, 7p, 8p, 8q, 9p, 11q, 12q, 16p, 20p and 20q)...
  40. ncbi request reprint The association between childhood depression and adulthood body mass index
    D S Pine
    Division of Child Psychiatry, New York State Psychiatric Institute and Columbia University, New York, New York 10032, USA
    Pediatrics 107:1049-56. 2001
    ..However, there are limited data on the association between major depression in childhood and BMI in adulthood. The current study examines this association...
  41. ncbi request reprint Maternal smoking during pregnancy and psychopathology in offspring followed to adulthood
    M M Weissman
    New York State Psychiatric Institute, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 38:892-9. 1999
    ..To extend findings from several independent reports of an association between maternal smoking during pregnancy and attention-deficit hyperactivity disorder, conduct disorder, and substance abuse in the offspring...
  42. ncbi request reprint Psychiatric disorders and impairment in the children of opiate addicts: prevalances and distribution by ethnicity
    E V Nunes
    Depression Evaluation Service, New York State Psychiatric Institute, NY 10032, USA
    Am J Addict 9:232-41. 2000
    ..The results suggest children of patients in treatment for opiate dependence from diverse ethnic groups are at risk for psychopathology. Programs for early detection and intervention should be devised and evaluated...
  43. ncbi request reprint Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder
    R Goedken
    Department of Psychiatry, The University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
    Am J Med Genet 96:781-3. 2000
    ..Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781-783, 2000...
  44. ncbi request reprint False positive results: a challenge for psychiatric screening in primary care
    A C Leon
    Department of Psychiatry, Cornell University Medical College, NY 10021, USA
    Am J Psychiatry 154:1462-4. 1997
    ..The goal of this study was to characterize primary care patients with false positive results on screens for mental disorders...
  45. ncbi request reprint Brief screens for mental disorders in primary care
    A C Leon
    Department of Psychiatry, Cornell University Medical College, New York, NY 10021, USA
    J Gen Intern Med 11:426-30. 1996
    ..They detected previously unrecognized cases in this study and may prove to be valuable tools for psychiatric diagnosis in primary care...
  46. ncbi request reprint No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder
    S P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, USA
    Mol Psychiatry 6:59-65. 2001
    ..The results reported here provide little support for the role of these polymorphisms in panic disorder...
  47. ncbi request reprint Familial aggregation of delusional depression: re-examination in a recent family study
    R B Goldstein
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    Depress Anxiety 8:160-5. 1998
    ..In a new family study, we attempted to replicate these findings...
  48. ncbi request reprint Premorbid polysomnographic signs in depressed adolescents: a reanalysis of EEG sleep after longitudinal follow-up in adulthood
    R R Goetz
    Columbia University, College of Physicians and Surgeons, and New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 49:930-42. 2001
    ..This adds to the body of literature that highlights the importance of the first 100 min of the sleep period in depression...
  49. ncbi request reprint Using family studies to understand comorbidity
    P J Wickramaratne
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032
    Eur Arch Psychiatry Clin Neurosci 243:150-7. 1993
    ..These methods are illustrated, by applying them to data from a recent family study to investigate the relationship and the cause of comorbidity between panic disorder and major depressive disorder...
  50. ncbi request reprint A third-pass genome scan in panic disorder: evidence for multiple susceptibility loci
    Abby J Fyer
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University and New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 60:388-401. 2006
    ..Panic disorder (PD) is a common illness with a definite but "complex" genetic contribution and estimated heritability of 30-46%...
  51. pmc Panic disorder, social anxiety disorder, and a possible medical syndrome previously linked to chromosome 13
    Ardesheer Talati
    Department of Psychiatry, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Biol Psychiatry 63:594-601. 2008
    ..We present data from a new case-control study that replicates and extends the syndrome phenotype clinically...
  52. ncbi request reprint Early childhood sleep and eating problems as predictors of adolescent and adult mood and anxiety disorders
    Say How Ong
    Department of Child and Adolescent Psychiatry, Child Guidance Clinic, Institute of Mental Health, Singapore
    J Affect Disord 96:1-8. 2006
    ..We aim to study the associations between early childhood sleep and eating problems, specifically high motor activity during sleep and irregularities in sleep/eating schedules, and lifetime history of mood and anxiety disorders...
  53. pmc Low birth weight and risk of affective disorders and selected medical illness in offspring at high and low risk for depression
    Yoko Nomura
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Compr Psychiatry 48:470-8. 2007
    ..05), suggesting that parental depression may augment the impact of LBW on offspring depression:..
  54. pmc Posttraumatic stress disorder in primary care one year after the 9/11 attacks
    Yuval Neria
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Gen Hosp Psychiatry 28:213-22. 2006
    ..To screen for posttraumatic stress disorder (PTSD) in primary care patients 7-16 months after 9/11 attacks and to examine its comorbidity, clinical presentation and relationships with mental health treatment and service utilization...
  55. ncbi request reprint Family discord, parental depression, and psychopathology in offspring: 20-year follow-up
    Daniel J Pilowsky
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, USA
    J Am Acad Child Adolesc Psychiatry 45:452-60. 2006
    ..To determine the independent effects of parental depression and family discord on offspring psychopathology among children at high and low risk of depression...
  56. pmc Remission of maternal depression and child symptoms among single mothers: a STAR*D-Child report
    Ardesheer Talati
    Dept of Psychiatry, Columbia University, 1051 Riverside Drive, Unit 24, New York, NY 10032, USA
    Soc Psychiatry Psychiatr Epidemiol 42:962-71. 2007
    ..This report examined the relationship of the presence of a father in the household to maternal depression remission and child outcomes...
  57. pmc A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity
    Francis M Mondimore
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Affect Disord 100:171-7. 2007
    ..Because familial clustering is one component of diagnostic validity we compared family clustering of chronicity as defined in the DSM-IV to that of chronicity determined by an assessment of lifetime course of depressive illness...
  58. ncbi request reprint Screening for bipolar disorder in the community
    Robert M A Hirschfeld
    Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, 77555 188, USA
    J Clin Psychiatry 64:53-9. 2003
    ..Our goal was to estimate the rate of positive screens for bipolar I and bipolar II disorders in the general population of the United States...
  59. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): final genome scan report
    Peter Holmans
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:248-58. 2007
    ....
  60. pmc Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Biol Psychiatry 63:1185-9. 2008
    ..Here we present initial linkage-disequilibrium (LD) fine mapping of this signal and sequence analysis of NTRK3 (neurotrophic receptor kinase-3), a biologically plausible candidate gene...
  61. ncbi request reprint Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1079-82. 2007
    ..2%, P = 0.15). None of the tag SNPs showed any evidence of association. Our results do not support a major role for either common or rare p11 SNPs with MDD. Several limitations of the study are discussed...
  62. doi request reprint Change in child psychopathology with improvement in parental depression: a systematic review
    MEREDITH L GUNLICKS
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 47:379-89. 2008
    ..To systematically review current research evidence of associations between improvement in parents' depression and their children's psychopathology...
  63. ncbi request reprint Familial depression and respiratory illness in children
    Renee D Goodwin
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Pediatr Adolesc Med 161:487-94. 2007
    ..To determine the relationship between parental major depression and respiratory illness in youth...
  64. pmc Grandchildren at high and low risk for depression differ in EEG measures of regional brain asymmetry
    Gerard E Bruder
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 62:1317-23. 2007
    ..Resting electroencephalogram (EEG) was measured in grandchildren participating in a multigenerational high-risk study...
  65. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:259-64. 2007
    ....
  66. pmc Trauma exposure and posttraumatic stress disorder among primary care patients with bipolar spectrum disorder
    Yuval Neria
    Department of Psychiatry, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University Medical Center, New York, NY 10032, USA
    Bipolar Disord 10:503-10. 2008
    ..To examine relationships between exposure to trauma, bipolar spectrum disorder (BD) and posttraumatic stress disorder (PTSD) in a sample of primary care patients...
  67. doi request reprint Children of depressed mothers 1 year after the initiation of maternal treatment: findings from the STAR*D-Child Study
    Daniel J Pilowsky
    New York State Psychiatric Institute, Columbia University, Unit 24, 1051 Riverside Dr, New York, NY 10032, USA
    Am J Psychiatry 165:1136-47. 2008
    ..The authors examined the changes in psychiatric symptoms and global functioning in children of depressed women 1 year following the initiation of treatment for maternal major depressive disorder...
  68. ncbi request reprint Familial aggregation of illness chronicity in recurrent, early-onset major depression pedigrees
    Francis M Mondimore
    Johns Hopkins Hospital, Meyer 3 181, 600 North Wolfe St, Baltimore, MD 21287, USA
    Am J Psychiatry 163:1554-60. 2006
    ..The authors used a large sample collected for genetic studies to determine whether a chronic course of illness defines a familial clinical subtype in major depressive disorder...
  69. ncbi request reprint Children of currently depressed mothers: a STAR*D ancillary study
    Daniel J Pilowsky
    Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Psychiatry 67:126-36. 2006
    ....
  70. ncbi request reprint Depression in African Americans: breaking barriers to detection and treatment
    Amar K Das
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    J Fam Pract 55:30-9. 2006
    ..We reviewed the literature to find evidence of specific patient, physician, and practice-setting factors related to such barriers...
  71. ncbi request reprint Asthma and mental disorders in primary care
    Renee D Goodwin
    Departments of Epidemiology, Columbia University College of Physicians, Columbia University, New York, NY, USA
    Gen Hosp Psychiatry 25:479-83. 2003
    ..Physicians who treat patients with asthma should remain vigilant for the presence of comorbid psychiatric problems and carefully evaluate whether there is a clinical need to treat each condition...
  72. ncbi request reprint Neurological soft signs and disruptive behavior among children of opiate dependent parents
    Jeffrey J Wilson
    Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Child Psychiatry Hum Dev 34:19-34. 2003
    ....
  73. ncbi request reprint Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life
    Dennis S Charney
    National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Arch Gen Psychiatry 60:664-72. 2003
    ..To review progress made during the past decade in late-life mood disorders and to identify areas of unmet need in health care delivery and research...
  74. ncbi request reprint Differentiating depressed adolescent 24 h cortisol secretion in light of their adult clinical outcome
    Sanjay J Mathew
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, USA
    Neuropsychopharmacology 28:1336-43. 2003
    ..Dysregulation of the HPA axis, combined with dysfunction of sleep-onset mechanisms previously reported in this same cohort, might serve as premorbid biological substrates that predict suicide attempts during follow-up...
  75. ncbi request reprint Parental depression, child mental health problems, and health care utilization
    Mark Olfson
    New York State Psychiatric Institute Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA
    Med Care 41:716-21. 2003
    ..Small controlled studies suggest that depression and other mental health problems are more common in children of parents with depression than in children of parents without depression...
  76. ncbi request reprint Screening for depression in adults
    Amar K Das
    Ann Intern Med 138:767; author reply 767-8. 2003
  77. ncbi request reprint Genetics of recurrent early-onset depression (GenRED): design and preliminary clinical characteristics of a repository sample for genetic linkage studies
    Douglas F Levinson
    Department of Psychiatry and Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 3309, USA
    Am J Med Genet B Neuropsychiatr Genet 119:118-30. 2003
    ..This suggests comparability of our cases to those in earlier large family studies. This dataset should prove useful for genetic studies of a highly familial form of major depressive disorder...
  78. pmc Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q
    Steven P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:2550-5. 2003
    ....
  79. ncbi request reprint Recall of childhood psychopathology more than 10 years later
    Carrie L Masia
    New York University School of Medicine, Child Study Center, New York, NY 10016, USA
    J Am Acad Child Adolesc Psychiatry 42:6-12. 2003
    ..Strengths of this study were that the length of the retest interval was substantial, follow-up information was collected by blind interviewers, and childhood diagnoses were clearly documented...
  80. ncbi request reprint Psychotic symptoms in an urban general medicine practice
    Mark Olfson
    College of Physicians and Surgeons of Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Am J Psychiatry 159:1412-9. 2002
    ....
  81. ncbi request reprint National trends in the use of psychotropic medications by children
    Mark Olfson
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University New York State Psychiatric Institute, New York, USA
    J Am Acad Child Adolesc Psychiatry 41:514-21. 2002
    ..The objective of this report is to compare patterns and predictors of psychotropic medication use by children and adolescents in the United States in 1987 and 1996...
  82. ncbi request reprint Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22
    Steven P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University, New York, NY, USA
    Biol Psychiatry 51:591-601. 2002
    ....
  83. ncbi request reprint Family discord, parental depression, and psychopathology in offspring: ten-year follow-up
    Yoko Nomura
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 41:402-9. 2002
    ..To determine the independent effects of parental depression and family discord on psychopathology in offspring at high and low risk for major depression...
  84. ncbi request reprint Treatment of depressed mothers of depressed children: pilot study of feasibility
    Helen Verdeli
    Divisions of Child Psychiatry and Clinical and Genetic Epidemiology, New York State Psychiatric Institute, Columbia University, New York, New York 10032, USA
    Depress Anxiety 19:51-8. 2004
    ..It may be more feasible to study the effect of improved maternal depression on offspring by sampling depressed mothers coming for their own treatment and then assessing their children over the course of maternal treatment...
  85. ncbi request reprint Investigation of polymorphisms in the CREM gene in panic disorder
    Steven P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Med Genet B Neuropsychiatr Genet 126:111-5. 2004
    ..These findings provide little additional evidence for a susceptibility locus for panic disorder either within the CREM gene or in a nearby region of chromosome 10p11 in our sample...
  86. ncbi request reprint Bipolar depression in a low-income primary care clinic
    Mark Olfson
    New York State Psychiatric Institute, Department of Psychiatry, Columbia University, 1051 Riverside Dr, Unit 24, New York, NY 10032, USA
    Am J Psychiatry 162:2146-51. 2005
    ....
  87. pmc Panic disorder and suicidal ideation in primary care
    Daniel J Pilowsky
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, New York, USA
    Depress Anxiety 23:11-6. 2006
    ..PD patients in primary care thus should be assessed routinely for suicidal ideation and depression...
  88. ncbi request reprint Depression in US Hispanics: diagnostic and management considerations in family practice
    Roberto Lewis-Fernandez
    Department of Psychiatry, Columbia University, New York, USA
    J Am Board Fam Pract 18:282-96. 2005
    ....
  89. pmc Depression and glycemic control in Hispanic primary care patients with diabetes
    Raz Gross
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY, USA
    J Gen Intern Med 20:460-6. 2005
    ..Although depression is common in adults with diabetes, its relationship to glycemic control remains unclear, especially among Hispanics...
  90. ncbi request reprint Social anxiety disorder in primary care
    Raz Gross
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Gen Hosp Psychiatry 27:161-8. 2005
    ..To examine the prevalence, comorbidity, disability and mental health treatment associated with social anxiety disorder (SAD) in primary care, and to determine whether patients with SAD avoid seeking help from their primary care providers...
  91. ncbi request reprint Families at high and low risk for depression: a three-generation startle study
    Christian Grillon
    Mood and Anxiety Disorder Program, National Institute of Mental Health, Bethesda, Maryland 20892 2670, USA
    Biol Psychiatry 57:953-60. 2005
    ....
  92. ncbi request reprint Screening for bipolar disorder in a primary care practice
    Amar K Das
    Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York 10032, USA
    JAMA 293:956-63. 2005
    ..Bipolar disorder consists of episodes of manic and depressive symptoms. Efforts to screen for depression in a primary care setting without assessment of past manic symptoms can lead to incorrect diagnosis and treatment of bipolar disorder...
  93. ncbi request reprint Electroencephalographic measures of regional hemispheric activity in offspring at risk for depressive disorders
    Gerard E Bruder
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, New York, USA
    Biol Psychiatry 57:328-35. 2005
    ..In a longitudinal high-risk study, resting EEG was measured in primarily adult offspring of depressed or nondepressed probands...
  94. ncbi request reprint Effectiveness research: transporting interpersonal psychotherapy for depressed adolescents (IPT-A) from the lab to school-based health clinics
    Laura H Mufson
    Division of Clinical and Genetic Epidemiology, Department of Psychiatry, New York State Psychiatric Institute, New York, New York, USA
    Clin Child Fam Psychol Rev 7:251-61. 2004
    ..Recommendations for conducting research in school-based practice settings are provided...
  95. ncbi request reprint Bipolar disorder
    Raz Gross
    N Engl J Med 351:2454-5. 2004
  96. ncbi request reprint Twenty-four-hour cortisol secretion patterns in prepubertal children with anxiety or depressive disorders
    Adriana Feder
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, USA
    Biol Psychiatry 56:198-204. 2004
    ..In this study, we combined data from two independent, consecutive studies to achieve a larger sample size. Our goal was to identify potential alterations in the circadian pattern of cortisol secretion in anxious or depressed children...
  97. ncbi request reprint A randomized effectiveness trial of interpersonal psychotherapy for depressed adolescents
    Laura Mufson
    Department of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, NY, USA
    Arch Gen Psychiatry 61:577-84. 2004
    ..The school-based health clinic offers the potential for accessible and efficient treatment, although it is unknown whether school-based clinicians can be trained to implement evidence-based psychotherapies for depression in routine care...
  98. pmc Genomewide significant linkage to recurrent, early-onset major depressive disorder on chromosome 15q
    Peter Holmans
    Biostatistics and Bioinformatics Unit, University of Wales College of Medicine, Cardiff, United Kingdom
    Am J Hum Genet 74:1154-67. 2004
    ..Chromosome 15q25.3-26.2 deserves further study as a candidate region for susceptibility to MDD...
  99. ncbi request reprint Borderline personality disorder in primary care
    Raz Gross
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 600 W 168 St, PH 18, Room 303, New York, NY 10032, USA
    Arch Intern Med 162:53-60. 2002
    ..Few data are available on its prevalence or clinical presentation outside of specialty mental health care settings...

Research Grants36

  1. GENETIC STUDIES OF DEPRESSIVE DISORDERS
    Myrna Weissman; Fiscal Year: 2003
    ..Understanding the etiology of PD will eventually facilitate the development of more effective treatment and preventive intervention. ..
  2. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    MYRNA M contact WEISSMAN; Fiscal Year: 2010
    ..Identifying the biological vulnerability for depression before the onset of illness, as we have described in the study, has important implications for prevention and public health. ..
  3. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2006
    ....
  4. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2002
    ..Moreover, the biological markers will offer another tool for refining the phenotype for genetic and other studies and for identifying high risk offspring. ..
  5. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2002
    ..A timetable is proposed for rapid sharing of all biological materials, blinded clinical data, genotypes and linkage analyses with the scientific community through the NIMH-sponsored Center for Genetic Studies. ..
  6. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2002
    ..will moderate the effect. If it is shown that successfully treating maternal depression is associated with diminished risk in offspring, the finding would have wide ranging public health implications. ..
  7. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2007
    ..abstract_text> ..
  8. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2003
    ....
  9. Parental Remission from Depression and Child Psychopathology
    Myrna Weissman; Fiscal Year: 2009
    ..At a time when the treatment of depressed and anxious children is uncertain, new strategies are needed. ..
  10. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2003
    ..will moderate the effect. If it is shown that successfully treating maternal depression is associated with diminished risk in offspring, the finding would have wide ranging public health implications. ..
  11. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2007
    ....
  12. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2004
    ..will moderate the effect. If it is shown that successfully treating maternal depression is associated with diminished risk in offspring, the finding would have wide ranging public health implications. ..
  13. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2005
    ....
  14. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2001
    ..A timetable is proposed for rapid sharing of all biological materials, blinded clinical data, genotypes and linkage analyses with the scientific community through the NIMH-sponsored Center for Genetic Studies. ..
  15. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2001
    ..will moderate the effect. If it is shown that successfully treating maternal depression is associated with diminished risk in offspring, the finding would have wide ranging public health implications. ..
  16. Parental Remission from Depression and Child Psychopathology
    Myrna Weissman; Fiscal Year: 2007
    ..At a time when the treatment of depressed and anxious children is uncertain, new strategies are needed. ..
  17. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2000
    ..Moreover, the biological markers will offer another tool for refining the phenotype for genetic and other studies and for identifying high risk offspring. ..
  18. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2000
    ..A timetable is proposed for rapid sharing of all biological materials, blinded clinical data, genotypes and linkage analyses with the scientific community through the NIMH-sponsored Center for Genetic Studies. ..
  19. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2001
    ..Moreover, the biological markers will offer another tool for refining the phenotype for genetic and other studies and for identifying high risk offspring. ..
  20. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2007
    ..abstract_text> ..
  21. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2006
    ..abstract_text> ..
  22. GENETICS OF EARLY-ONSET MAJOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2005
    ..abstract_text> ..
  23. Children of Depressed Mothers: a STAR*D Ancillary Study
    Myrna Weissman; Fiscal Year: 2005
    ..will moderate the effect. If it is shown that successfully treating maternal depression is associated with diminished risk in offspring, the finding would have wide ranging public health implications. ..
  24. GENETIC STUDIES OF DEPRESSIVE DISORDERS
    Myrna Weissman; Fiscal Year: 2002
    ..Understanding the etiology of PD will eventually facilitate the development of more effective treatment and preventive intervention. ..
  25. Parental Remission from Depression and Child Psychopathology
    Myrna M Weissman; Fiscal Year: 2010
    ..At a time when the treatment of depressed and anxious children is uncertain, new strategies are needed. ..
  26. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 2004
    ....
  27. CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION
    Myrna Weissman; Fiscal Year: 1999
    ..Moreover, the biological markers will offer another tool for refining the phenotype for genetic and other studies and for identifying high risk offspring. ..