ZiMian Wang

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Body cell mass: model development and validation at the cellular level of body composition
    ZiMian Wang
    Weight Control Unit, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 286:E123-8. 2004
  2. doi New insights into scaling of fat-free mass to height across children and adults
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York City, New York, USA
    Am J Hum Biol 24:648-53. 2012
  3. doi High ratio of resting energy expenditure to body mass in childhood and adolescence: a mechanistic model
    ZiMian Wang
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, NY 10025, USA
    Am J Hum Biol 24:460-7. 2012
  4. pmc Evaluation of specific metabolic rates of major organs and tissues: comparison between nonobese and obese women
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York City, New York, USA
    Obesity (Silver Spring) 20:95-100. 2012
  5. ncbi Cellular-level body composition model. A new approach to studying fat-free mass hydration
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA
    Ann N Y Acad Sci 904:306-11. 2000
  6. pmc A new total body potassium method to estimate total body skeletal muscle mass in children
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    J Nutr 137:1988-91. 2007
  7. pmc Estimation of percentage body fat by dual-energy x-ray absorptiometry: evaluation by in vivo human elemental composition
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Phys Med Biol 55:2619-35. 2010
  8. ncbi The reconstruction of Kleiber's law at the organ-tissue level
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    J Nutr 131:2967-70. 2001
  9. pmc Metabolically active portion of fat-free mass: a cellular body composition level modeling analysis
    ZiMian Wang
    Obesity Research Center, 1090 Amsterdam Ave, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 292:E49-53. 2007
  10. ncbi Total body protein mass: validation of total body potassium prediction model in children and adolescents
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nutr 136:1032-6. 2006

Collaborators

Detail Information

Publications70

  1. ncbi Body cell mass: model development and validation at the cellular level of body composition
    ZiMian Wang
    Weight Control Unit, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 286:E123-8. 2004
    ..0083 x TBK) formulated on rough tissue composition estimates. The present analyses provide a physiologically based, improved, and validated TBK-BCM prediction formula that should prove useful in body composition and metabolism research...
  2. doi New insights into scaling of fat-free mass to height across children and adults
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York City, New York, USA
    Am J Hum Biol 24:648-53. 2012
    ..Forbes expressed fat-free mass (FFM, in kg) as the cube of height (H, in m): FFM = 10.3 × H(3). Our objective is to examine the potential influence of gender and population ancestry on the association between FFM and height...
  3. doi High ratio of resting energy expenditure to body mass in childhood and adolescence: a mechanistic model
    ZiMian Wang
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, NY 10025, USA
    Am J Hum Biol 24:460-7. 2012
    ..Children have lower resting energy expenditure (REE) but higher ratio of resting energy expenditure to body mass (REE/BM) than do adults. This well-known observation has never been quantitatively explained...
  4. pmc Evaluation of specific metabolic rates of major organs and tissues: comparison between nonobese and obese women
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York City, New York, USA
    Obesity (Silver Spring) 20:95-100. 2012
    ..7 for skeletal muscle, 4.4 for adipose tissue, and 11.8 for residual mass. In conclusion, although Elia's K(i) values were validated in nonobese women, obesity-adjustments are appropriate for application in obese women...
  5. ncbi Cellular-level body composition model. A new approach to studying fat-free mass hydration
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA
    Ann N Y Acad Sci 904:306-11. 2000
    ..73, and a variation range 0.69-0.77. The suggested modeling approach provides a conceptual framework for TBW-fat estimation method and identifies important areas that remain to be studied...
  6. pmc A new total body potassium method to estimate total body skeletal muscle mass in children
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    J Nutr 137:1988-91. 2007
    ..Because the adult TBK SM prediction model is not applicable for pediatric use, this study provides new empirical TBK SM prediction equations that should prove useful for studies on nutrition, growth, and development in children...
  7. pmc Estimation of percentage body fat by dual-energy x-ray absorptiometry: evaluation by in vivo human elemental composition
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Phys Med Biol 55:2619-35. 2010
    ..4 +/- 12.0% versus 24.9 +/- 11.1%, r = 0.983, P < 0.001). DXA R(ST) is evaluated by in vivo elemental composition, and the present study supports the underlying physical concept and accuracy of the DXA method for estimating %fat...
  8. ncbi The reconstruction of Kleiber's law at the organ-tissue level
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    J Nutr 131:2967-70. 2001
    ..76)) is similar to that observed by Kleiber on the whole-body level. Modeling mammalian REE at the organ-tissue level provides new insights and pathways for future mechanistic explorations of REE-body composition relationships...
  9. pmc Metabolically active portion of fat-free mass: a cellular body composition level modeling analysis
    ZiMian Wang
    Obesity Research Center, 1090 Amsterdam Ave, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 292:E49-53. 2007
    ..584 +/- 0.041 and 0.529 +/- 0.041 for adult men and women (P < 0.001), respectively. A multiple linear regression model showed that there are independent significant associations of sex, age, and fat mass with BCM/FFM...
  10. ncbi Total body protein mass: validation of total body potassium prediction model in children and adolescents
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nutr 136:1032-6. 2006
    ..032, P > 0.05). The TBK-Mo model can thus be used to estimate TBPro in healthy adults, adolescents, and children > 5 y old...
  11. ncbi A cellular-level approach to predicting resting energy expenditure across the adult years
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Am J Clin Nutr 81:799-806. 2005
    ..Although the model predicted REE well in young persons, it overpredicted REE by approximately 11% in elderly adults. This overprediction may occur because of a decline in the fraction of organs and tissues as cell mass with aging...
  12. ncbi Multicomponent methods: evaluation of new and traditional soft tissue mineral models by in vivo neutron activation analysis
    ZiMian Wang
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 76:968-74. 2002
    ..Practical and accurate methods for quantifying the soft tissue mineral component of multicomponent fat-estimation models are needed...
  13. ncbi Whole-body skeletal muscle mass: development and validation of total-body potassium prediction models
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Am J Clin Nutr 77:76-82. 2003
    ..There are now > 30 whole-body counters worldwide that have large cross-sectional and longitudinal TBK databases...
  14. ncbi Total body protein: a new cellular level mass and distribution prediction model
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 78:979-84. 2003
    ....
  15. ncbi Magnitude and variation of fat-free mass density: a cellular-level body composition modeling study
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York 10025, USA
    Am J Physiol Endocrinol Metab 284:E267-73. 2003
    ..The difference in FFM density across sex, race, and age groups was examined with the developed model. The present study thus provides a conceptual framework for the systematic study of FFM density in humans...
  16. ncbi Muscularity in adult humans: proportion of adipose tissue-free body mass as skeletal muscle
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Am J Hum Biol 13:612-9. 2001
    ..In addition, the SM/ATFM ratio was significantly lower in AIDS patients than corresponding values in healthy subjects...
  17. pmc Evaluation of specific metabolic rates of major organs and tissues: comparison between men and women
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Biol 23:333-8. 2011
    ..However, it is unknown whether gender influences the K(i) values. The aim of the present study was to compare the K(i) values observed in nonelderly nonobese men to the corresponding values in women...
  18. ncbi Hydration of fat-free body mass: new physiological modeling approach
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Am J Physiol 276:E995-E1003. 1999
    ..The present study, the first to advance a physiological hydration model, provides a conceptual framework for the TBW-fat estimation method and identifies important areas that remain to be studied...
  19. ncbi Hydration of fat-free body mass: review and critique of a classic body-composition constant
    Z Wang
    St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 69:833-41. 1999
    ..These are important issues because water dilution is the only method currently available for estimating body fat in all mammals, which range in body mass by a factor of 10(4)...
  20. doi Total body carbon and oxygen masses: evaluation of dual-energy x-ray absorptiometry estimation by in vivo neutron activation analysis
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, NY, USA
    Phys Med Biol 55:5953-63. 2010
    ..As both DXA and TBW dilutions are widely available, low-risk, low-cost techniques, the present study provides a safe and practical method for estimating elemental composition in vivo...
  21. ncbi Resting energy expenditure-fat-free mass relationship: new insights provided by body composition modeling
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Am J Physiol Endocrinol Metab 279:E539-45. 2000
    ....
  22. pmc A cellular level approach to predicting resting energy expenditure: Evaluation of applicability in adolescents
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, New York, NY, USA
    Am J Hum Biol 22:476-83. 2010
    ..A modified general REE prediction model is thus suggested which may account for the higher REE/FFM ratio observed in adolescents...
  23. ncbi Resting energy expenditure: systematic organization and critique of prediction methods
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Obes Res 9:331-6. 2001
    ....
  24. ncbi Magnitude and variation of ratio of total body potassium to fat-free mass: a cellular level modeling study
    Z Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Am J Physiol Endocrinol Metab 281:E1-7. 2001
    ..The present study provides a conceptual framework for examining the separate TBK/FFM determinants and suggests important limitations of the TBK/FFM method used in estimating total body fat in humans and other mammals...
  25. pmc Specific metabolic rates of major organs and tissues across adulthood: evaluation by mechanistic model of resting energy expenditure
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 92:1369-77. 2010
    ..5 for adipose tissue, and 12 for residual organs and tissues. However, Elia's K(i) values have never been fully evaluated...
  26. pmc Evaluation of between-methods agreement of extracellular water measurements in adults and children
    Analiza M Silva
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University Institute of Human Nutrition, College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 88:315-23. 2008
    ..Extracellular water (ECW), a relevant molecular level component for clinical assessment, is commonly obtained by 2 methods that rely on assumptions that may not be possible to test at the time the measurements are made...
  27. ncbi Body-composition differences between African American and white women: relation to resting energy requirements
    Alfredo Jones
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, Weight Control Unit, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Am J Clin Nutr 79:780-6. 2004
    ..Body composition differs between African American (AA) and white women, and the resting metabolic rate (RMR) is likely to be lower in AA women than in white women...
  28. ncbi Total body potassium differs by sex and race across the adult age span
    Qing He
    Obesity Research Center, St Luke s Roosevelt Hospital, and Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY 1025, USA
    Am J Clin Nutr 78:72-7. 2003
    ..Total body potassium (TBK) is an index of fat-free mass. Data describing changes in TBK in African American, Asian, or Hispanic populations have not been reported...
  29. ncbi DXA: potential for creating a metabolic map of organ-tissue resting energy expenditure components
    Matthew Hayes
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA
    Obes Res 10:969-77. 2002
    ....
  30. ncbi Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image
    Wei Shen
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, New York, NY, USA
    J Appl Physiol (1985) 97:2333-8. 2004
    ..Measurement of a single abdominal image can thus provide estimates of total body SM and AT for group studies of healthy adults...
  31. pmc Total-body skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in children and adolescents
    Jaehee Kim
    Obesity Research Center, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Clin Nutr 84:1014-20. 2006
    ..Skeletal muscle (SM) is an important compartment but is difficult to quantify in children and adolescents...
  32. ncbi Dual-energy X-ray absorptiometry lean soft tissue hydration: independent contributions of intra- and extracellular water
    Marie Pierre St-Onge
    St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New Youk, NY 10025, USA
    Am J Physiol Endocrinol Metab 287:E842-7. 2004
    ..This observation has implications for the accuracy of body fat measurements by DEXA and the use of TBW as a means of checking DEXA system calibration...
  33. ncbi Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites
    Shankuan Zhu
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center and Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, USA
    Obes Res 12:633-45. 2004
    ..The present study sought to identify the combination of BMI and WC that has the strongest association with CVD risk factors in whites...
  34. pmc Visceral adipose tissue: relations between single-slice areas and total volume
    Wei Shen
    Obesity Research Center, St Luke s Roosevelt Hospital, and the Institute of Human Nutrition, Columbia University, College of Physicians and Surgeons, 1090 Amsterdam Avenue, New York, NY 10025, USA
    Am J Clin Nutr 80:271-8. 2004
    ..However, the location of the slice with the strongest relation to VAT volume is not established...
  35. pmc Four-compartment cellular level body composition model: comparison of two approaches
    Wei Shen
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons and Institute of Human Nutrition, Weight Control Unit, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Obes Res 13:58-65. 2005
    ..The aim of this study was to develop and compare two DXA-based four-compartment [body weight=body cell mass (BCM)+extracellular fluid (ECF)+extracellular solids (ECS)+fat] cellular level models...
  36. ncbi Dual-energy x-ray absorptiometry-measured lean soft tissue mass: differing relation to body cell mass across the adult life span
    Marie Pierre St-Onge
    St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Gerontol A Biol Sci Med Sci 59:796-800. 2004
    ..001) than women; quadratic and cubic age terms were also significant or approached significance. Thus, the fraction of LST as BCM is smaller in older adults, a finding that has implications for the interpretation of DEXA results...
  37. ncbi Percentage body fat ranges associated with metabolic syndrome risk: results based on the third National Health and Nutrition Examination Survey (1988-1994)
    Shankuan Zhu
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, USA
    Am J Clin Nutr 78:228-35. 2003
    ..Increasing attention has focused on the association between body fatness and related metabolic risk factors. The quantitative link between percentage body fat (%BF) and the risk of metabolic syndrome is unknown...
  38. pmc Volume estimates by imaging methods: model comparisons with visible woman as the reference
    Wei Shen
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, New York, USA
    Obes Res 11:217-25. 2003
    ..To compare the accuracy of four volume estimation models to actual tissue and organ volumes measured in the visible woman...
  39. ncbi Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds
    Shankuan Zhu
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    Am J Clin Nutr 76:743-9. 2002
    ..Waist circumference (WC) is strongly linked to obesity-associated risks. However, currently proposed WC risk thresholds are not based on associations with obesity-related risk factors but rather with body mass index (BMI; in kg/m(2))...
  40. ncbi Body-size dependence of resting energy expenditure can be attributed to nonenergetic homogeneity of fat-free mass
    Steven B Heymsfield
    New York Obesity Research Center, St Luke s Roosevelt Hospital, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 282:E132-8. 2002
    ..These observations have important implications for the interpretation of between-individual differences in REE expressed relative to metabolically active tissue mass...
  41. ncbi Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method
    Jaehee Kim
    Obesity Research Center, St Luke s Roosevelt Hospital and the Institute of Human Nutrition, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 76:378-83. 2002
    ..A large proportion of total-body SM is found in the extremities, and a large proportion of extremity lean soft tissue is SM. A strong link should thus exist between appendicular lean soft tissue (ALST) mass and total-body SM mass...
  42. ncbi Body composition in pediatrics to geriatrics: a lesson for nutritional monitoring
    Steven B Heymsfield
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, and Institute of Human Nutrition, College of Physicians and Surgeons, New York, N Y, USA
    Nestle Nutr Workshop Ser Clin Perform Programme 7:239-50; discussion 250-5. 2002
  43. doi Advances in the understanding of specific metabolic rates of major organs and tissues in humans
    Manfred J Muller
    Institut fur Humanernahrung und Lebensmittelkunde, Christian Albrechts Universitat zu Kiel, Germany
    Curr Opin Clin Nutr Metab Care 16:501-8. 2013
    ..To present recent evidence on organ and tissue metabolic rates in humans to explain the variance in resting energy expenditure (REE)...
  44. pmc Adipose tissue quantification by imaging methods: a proposed classification
    Wei Shen
    Obesity Research Center, St Luke s Roosevelt Hospital and Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Obes Res 11:5-16. 2003
    ..This analysis leads us to propose an updated classification of total body and regional adipose tissue, providing a well-defined basis for correlating imaging studies of specific adipose tissue depots with molecular processes...
  45. ncbi Techniques used in measuring human body composition
    A Pietrobelli
    Obesity Research Centre, Saint Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Curr Opin Clin Nutr Metab Care 1:439-48. 1998
    ..As the dual-energy X-ray absorptiometry is now gaining acceptance, both clinically and in the research laboratory, as a useful body composition method, particular emphasis is placed on this important approach...
  46. ncbi Body composition modeling. Application to exploration of the resting energy expenditure fat-free mass relationship
    S B Heymsfield
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA
    Ann N Y Acad Sci 904:290-7. 2000
    ....
  47. ncbi Smaller organ tissue mass in the elderly fails to explain lower resting metabolic rate
    D Gallagher
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Ann N Y Acad Sci 904:449-55. 2000
    ..Further studies are required to investigate whether there is a reduction in the oxidative capacity of individual organs and tissues...
  48. pmc Constrained least absolute deviation neural networks
    Z Wang
    Division of Child Psychiatry, Columbia College of Physicians and Surgeons, New York, NY 10032, USA
    IEEE Trans Neural Netw 19:273-83. 2008
    ..The numerical simulations have also illustrated that the proposed CLADNN can be used to robustly estimate parameters for nonlinear curve fitting, which is extensively used in signal and image processing...
  49. ncbi Human body composition: advances in models and methods
    S B Heymsfield
    Obesity Research Center, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Annu Rev Nutr 17:527-58. 1997
    ..This review summarizes main body composition research concepts, examines new component-measurement methodologies, and identifies potential areas of future research...
  50. pmc Measurement of intramyocellular lipid levels with 2-D magnetic resonance spectroscopic imaging at 1.5 T
    W Shen
    Weight Control Unit, St Luke s Roosevelt Hospital, 1090 Amsterdam Ave, 14th Floor, New York, NY 10025, USA
    Acta Diabetol 40:S51-4. 2003
    ..This approach provided the spatial resolution and voxel placement flexibility permitting optimal separation of IMCL and extramyocellular lipid. Our findings demonstrate the potential of the SI approach...
  51. ncbi Techniques used in the measurement of body composition: an overview with emphasis on bioelectrical impedance analysis
    S B Heymsfield
    Department of Medicine, St Luke s Roosevel Hospital Center, New York, USA
    Am J Clin Nutr 64:478S-484S. 1996
    ..Body-composition research is a rapidly expanding area and in-depth systematic evaluation of new methods is a vital aspect of the field's growth...
  52. pmc Estimation of total body skeletal muscle mass in Chinese adults: prediction model by dual-energy X-ray absorptiometry
    Xinyu Zhao
    Obesity and Body Composition Research Center, Chronic Disease Research Institute, School of Public Health, Zhejiang University, Hangzhou, China
    PLoS ONE 8:e53561. 2013
    ..There are few reports on total body skeletal muscle mass (SM) in Chinese. The objective of this study is to establish a prediction model of SM for Chinese adults...
  53. ncbi Fasting downregulates renal water channel AQP2 and causes polyuria
    H Amlal
    Department of Medicine, University of Cincinnati Medical Center, 231 Bethesda Ave, MSB 5502, Cincinnati OH45267 0585, USA
    Am J Physiol Renal Physiol 280:F513-23. 2001
    ..We conclude that 1) fasting impairs the urinary concentrating ability in rats, and 2) the renal water-handling defect in fasting results specifically from the downregulation of AQP2 in the cortical and outer medullary collecting duct...
  54. pmc Truncal fat in relation to total body fat: influences of age, sex, ethnicity and fatness
    C H Wu
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, NY, USA
    Int J Obes (Lond) 31:1384-91. 2007
    ..To investigate the influence of age, sex, ethnicity and total fatness on central obesity in four ethnic populations...
  55. ncbi Hypertonicity-induced p38MAPK activation elicits recovery of corneal epithelial cell volume and layer integrity
    V N Bildin
    Department of Biological Sciences, College of Optometry, State University of New York, 33 West 42nd St, New York, NY 10036, USA
    J Membr Biol 193:1-13. 2003
    ..On the other hand, Erk1/2 activity restoration seems to be dependent on cell volume recovery...
  56. pmc Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice
    H G Zhang
    Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama Birmingham, Birmingham, Alabama 35294, USA
    J Clin Invest 105:813-21. 2000
    ..This organwide effect of APC-AdFasL appears to be mediated by elimination of activated T lymphocytes in the spleen before their emigration to the target organs...
  57. ncbi Low physical activity levels of modern Homo sapiens among free-ranging mammals
    M Hayes
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes (Lond) 29:151-6. 2005
    ..Our observations lend support to the hypothesis that low activity-related energy expenditure levels contribute to the rising worldwide prevalence of obesity...
  58. ncbi EGF stimulates growth by enhancing capacitative calcium entry in corneal epithelial cells
    H Yang
    SUNY, College of Optometry, Biological Sciences, 33 West 42nd Street, New York, NY 10036, USA
    J Membr Biol 194:47-58. 2003
    ..EGF induces CCE through its stimulation of Erkl/2 activity, whereas PKA stimulation suppresses these effects of EGF. TRP4 may be a component of plasma membrane SOC activity, which is stimulated by ICS calcium depletion...
  59. ncbi Normal development of mice lacking metablastin (P19), a phosphoprotein implicated in cell cycle regulation
    U K Schubart
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 271:14062-6. 1996
    ..Although the data suggest that metablastin is not essential for mammalian development, the knockout mice should prove valuable in exploring the role of this protein in cell cycle regulation...
  60. ncbi Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development
    R Zent
    Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0693, USA
    Dev Biol 238:289-302. 2001
    ..These data may help to partially explain the renal phenotype seen in integrin alpha3 and alpha3/alpha6 subunit-deficient animals...
  61. pmc Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split
    X Yu
    Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, New York 10021, USA
    Mol Cell Biol 21:4614-25. 2001
    ..These observations implicate AES as a selective repressor of ligand-dependent AR-mediated transcription that acts by directly interacting with AR and by targeting the basal transcription machinery...
  62. ncbi Cell signaling pathways mediating epidermal growth factor stimulation of Na:K:2Cl cotransport activity in rabbit corneal epithelial cells
    H Yang
    College of Optometry, Department of Biological Sciences, State University of New York, 33 W. 42nd Street, New York, NY 10036, USA
    J Membr Biol 183:93-101. 2001
    ..Taken together, EGF stimulates Erk1/2; p38 and cPLA2 activity. Their stimulation increases PGE2 and cAMP levels resulting in PKA and NKCC activation...
  63. ncbi MEK1/2 inhibitors promote Ara-C-induced apoptosis but not loss of Deltapsi(m) in HL-60 cells
    C Yu
    Department of Medicine, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Biochem Biophys Res Commun 286:1011-8. 2001
    ....
  64. ncbi Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors
    Shankuan Zhu
    Injury Research Center and Department of Family and Community Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Clin Nutr 81:409-15. 2005
    ..However, WC cutoffs for other race-ethnicity groups remain unknown...
  65. ncbi Extracellular water: greater expansion with age in African Americans
    Analiza M Silva
    Exercise and Health Laboratory, Faculty of Human Movement Technical University of Lisbon, Portugal
    J Appl Physiol 99:261-7. 2005
    ..05). The ECW compartment and E/I are thus variably larger, according to race, in healthy older subjects independent of sex, lean soft tissue, and fat mass...
  66. ncbi Three-compartment model: critical evaluation based on neutron activation analysis
    Analiza M Silva
    Exercise and Health Laboratory, Faculty of Human Movement, Technical University of Lisbon, 1495 688 Lisbon, Portugal
    Am J Physiol Endocrinol Metab 287:E962-9. 2004
    ..The present study results provide a critical evaluation of potential errors in the classic 3C model and present new formulas for use in selected populations...
  67. ncbi Comparison of visceral adipose tissue mass in adult African Americans and whites
    Daniel J Hoffman
    Department of Nutritional Sciences, Rutgers University, Room 230 Davison Hall, 26 Nichol Avenue, Room 228B, New Brunswick, NJ 08901, USA
    Obes Res 13:66-74. 2005
    ..This study was designed to measure the extent to which race is associated with VAT, controlling for total adipose tissue (TAT) mass and testosterone...
  68. ncbi Extracellular water across the adult lifespan: reference values for adults
    Analiza M Silva
    Exercise and Health Laboratory, Faculty of Human Movement, Technical University of Lisbon, Portugal
    Physiol Meas 28:489-502. 2007
    ....
  69. ncbi Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women
    Zhao Chen
    College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    J Nutr 137:2775-80. 2007
    ..We conclude that DXA is a reliable method for cross-sectional assessments of SMM in older women...
  70. ncbi The end of body composition methodology research?
    Steven B Heymsfield
    Curr Opin Clin Nutr Metab Care 8:591-4. 2005
    ..than small, incremental improvements in available methods, is there no longer a need for developing new body composition methods? This review examines the question: are we approaching the 'end' of body composition methodology research?..

Research Grants2

  1. Exploring Growth Energy Expenditure in Normal-Weight and Overweight Children
    ZiMian Wang; Fiscal Year: 2007
    ..Therefore, this study has the potential to answer an important question regarding the energy cost for synthesizing new BCM, and to contribute to our understanding of energy metabolism in growing normal-weight and overweight children. ..