Suzanne K Vosburg

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc A comparison among tapentadol tamper-resistant formulations (TRF) and OxyContin® (non-TRF) in prescription opioid abusers
    Suzanne K Vosburg
    Division on Substance Abuse, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Addiction 108:1095-106. 2013
  2. pmc Assessment of a formulation designed to be crush-resistant in prescription opioid abusers
    Suzanne K Vosburg
    Division on Substance Abuse, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, Department of Psychiatry, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 126:206-15. 2012
  3. ncbi request reprint An evaluation of the reinforcing effects of memantine in cocaine-dependent humans
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Drug Alcohol Depend 79:257-60. 2005
  4. pmc Using a novel alternative to drug choice in a human laboratory model of a cocaine binge: a game of chance
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, United States
    Drug Alcohol Depend 110:144-50. 2010
  5. pmc A human laboratory study investigating the effects of quetiapine on marijuana withdrawal and relapse in daily marijuana smokers
    Ziva D Cooper
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Addict Biol 18:993-1002. 2013
  6. pmc Comparison of a drug versus money and drug versus drug self-administration choice procedure with oxycodone and morphine in opioid addicts
    Sandra D Comer
    Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Behav Pharmacol 24:504-16. 2013
  7. ncbi request reprint Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, Columbia University, Columbia, New York 10032, USA
    Behav Pharmacol 18:71-5. 2007
  8. ncbi request reprint Smoked cocaine self-administration is decreased by modafinil
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 33:761-8. 2008
  9. pmc Modafinil does not serve as a reinforcer in cocaine abusers
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, United States
    Drug Alcohol Depend 106:233-6. 2010
  10. pmc Abuse liability of intravenous buprenorphine/naloxone and buprenorphine alone in buprenorphine-maintained intravenous heroin abusers
    Sandra D Comer
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Addiction 105:709-18. 2010

Detail Information

Publications45

  1. pmc A comparison among tapentadol tamper-resistant formulations (TRF) and OxyContin® (non-TRF) in prescription opioid abusers
    Suzanne K Vosburg
    Division on Substance Abuse, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Addiction 108:1095-106. 2013
    ....
  2. pmc Assessment of a formulation designed to be crush-resistant in prescription opioid abusers
    Suzanne K Vosburg
    Division on Substance Abuse, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, Department of Psychiatry, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 126:206-15. 2012
    ....
  3. ncbi request reprint An evaluation of the reinforcing effects of memantine in cocaine-dependent humans
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Drug Alcohol Depend 79:257-60. 2005
    ..Memantine was not reinforcing and subjective-effects ratings were not altered as a function of dose. Results suggest that these doses of memantine do not have abuse liability in cocaine-dependent individuals...
  4. pmc Using a novel alternative to drug choice in a human laboratory model of a cocaine binge: a game of chance
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, United States
    Drug Alcohol Depend 110:144-50. 2010
    ..The current model could be used to evaluate whether behavioral and pharmacological manipulations shift choice from cocaine to a non-drug alternative...
  5. pmc A human laboratory study investigating the effects of quetiapine on marijuana withdrawal and relapse in daily marijuana smokers
    Ziva D Cooper
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Addict Biol 18:993-1002. 2013
    ..However, quetiapine increased marijuana craving and marijuana self-administration during the relapse phase. These data do not suggest that quetiapine shows promise as a potential treatment for marijuana dependence. ..
  6. pmc Comparison of a drug versus money and drug versus drug self-administration choice procedure with oxycodone and morphine in opioid addicts
    Sandra D Comer
    Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Behav Pharmacol 24:504-16. 2013
    ..Both self-administration procedures were effective for assessing the relative reinforcing effects of drugs; preference for one procedure should be driven by the specific research question of interest. ..
  7. ncbi request reprint Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, Columbia University, Columbia, New York 10032, USA
    Behav Pharmacol 18:71-5. 2007
    ..Together, the data indicate that gabapentin does not show promise as a treatment medication for cocaine dependence...
  8. ncbi request reprint Smoked cocaine self-administration is decreased by modafinil
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 33:761-8. 2008
    ..Thus, our data support the potential of modafinil as a pharmacotherapy for cocaine dependence...
  9. pmc Modafinil does not serve as a reinforcer in cocaine abusers
    Suzanne K Vosburg
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, United States
    Drug Alcohol Depend 106:233-6. 2010
    ..Results suggest that modafinil does not have abuse liability in cocaine abusers...
  10. pmc Abuse liability of intravenous buprenorphine/naloxone and buprenorphine alone in buprenorphine-maintained intravenous heroin abusers
    Sandra D Comer
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Addiction 105:709-18. 2010
    ..This randomized, double-blind, cross-over study was conducted to assess the intravenous abuse potential of buprenorphine/naloxone compared with buprenorphine in buprenorphine-maintained injection drug users (IDUs)...
  11. pmc Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse
    Margaret Haney
    Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Psychopharmacology (Berl) 211:233-44. 2010
    ..Only a small percentage of individuals seeking treatment for their marijuana use achieves sustained abstinence, suggesting more treatment options are needed...
  12. pmc Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study
    Gillinder Bedi
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Psychopharmacology (Berl) 212:675-86. 2010
    ..HIV-negative marijuana smokers require higher than recommended dronabinol doses to experience expected effects...
  13. pmc Effects of acute oral naltrexone on the subjective and physiological effects of oral D-amphetamine and smoked cocaine in cocaine abusers
    Sandra D Comer
    Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, and College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Neuropsychopharmacology 38:2427-38. 2013
    ..Future studies should continue to evaluate NTX as a potential anti-craving medication for COC dependence. ..
  14. ncbi request reprint Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence
    Daniel J Brooks
    New York State Psychiatry Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
    J Addict Dis 25:15-25. 2006
    ..Diagnostic services capable of identifying cognitive deficits among MMP with ADHD and/or CD are needed to maximize the likelihood of treatment success and to serve as an indicator for the efficacy of therapeutic approaches...
  15. pmc Effects of repeated oxycodone administration on its analgesic and subjective effects in normal, healthy volunteers
    Ziva D Cooper
    Department of Psychiatry, Division on Substance Abuse, New York Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Behav Pharmacol 23:271-9. 2012
    ..These data also suggest that intermittent administration may enhance the analgesic effects of oxycodone, while also increasing some of the drug's positive subjective effects related to abuse liability...
  16. pmc Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse
    Margaret Haney
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY, 10032, USA
    Psychopharmacology (Berl) 197:157-68. 2008
    ..Individuals seeking treatment for their marijuana use rarely achieve sustained abstinence...
  17. pmc Nabilone decreases marijuana withdrawal and a laboratory measure of marijuana relapse
    Margaret Haney
    Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 38:1557-65. 2013
    ..Thus, nabilone maintenance produced a robust attenuation of marijuana withdrawal symptoms and a laboratory measure of relapse even with once per day dosing. These data support testing of nabilone for patients seeking marijuana treatment...
  18. pmc Buprenorphine/naloxone as a promising therapeutic option for opioid abusing patients with chronic pain: reduction of pain, opioid withdrawal symptoms, and abuse liability of oral oxycodone
    Perrine Roux
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, and College of Physicians and Surgeons, Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
    Pain 154:1442-8. 2013
    ..These data suggest that Bup/Nx was effective in reducing pain and supplemental oxycodone use. Importantly, adequate management of pain and withdrawal symptoms by Bup/Nx may reduce oxycodone preference in this population...
  19. pmc Predictors of marijuana relapse in the human laboratory: robust impact of tobacco cigarette smoking status
    Margaret Haney
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Biol Psychiatry 73:242-8. 2013
    ..Few marijuana smokers in treatment achieve sustained abstinence, yet factors contributing to high relapse rates are unknown...
  20. ncbi request reprint Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep
    Margaret Haney
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 45:545-54. 2007
    ..This placebo-controlled within-subjects study evaluated marijuana and dronabinol across a range of behaviors: eating topography, mood, cognitive performance, physiologic measures, and sleep...
  21. pmc The subjective, reinforcing, and analgesic effects of oxycodone in patients with chronic, non-malignant pain who are maintained on sublingual buprenorphine/naloxone
    Jermaine D Jones
    Division on Substance Abuse, New York State Psychiatric Institute College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 36:411-22. 2011
    ..These data suggest that sublingual Bup/Nx has the potential as an analgesic medication and further research should investigate its use in treating patients with chronic pain who abuse opioids...
  22. ncbi request reprint Memantine increases cardiovascular but not behavioral effects of cocaine in methadone-maintained humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Pharmacol Biochem Behav 83:47-55. 2006
    ..Taken together, these findings corroborate earlier data suggesting that this dose of memantine will not be helpful in the pharmacotherapy of cocaine abuse...
  23. ncbi request reprint Modafinil attenuates disruptions in cognitive performance during simulated night-shift work
    Carl L Hart
    Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 31:1526-36. 2006
    ..Therapeutic doses of modafinil attenuated night-shift-associated disruptions, but the larger dose produced some sleep impairments when administered during day-shift work...
  24. doi request reprint Methamphetamine self-administration by humans subjected to abrupt shift and sleep schedule changes
    Matthew G Kirkpatrick
    Department of Psychology, Columbia University, New York, USA
    Psychopharmacology (Berl) 203:771-80. 2009
    ..Methamphetamine attenuates disruptions that occur after changes in work shifts. The reinforcing effects of the drug during shift work have yet to be characterized...
  25. ncbi request reprint Depot naltrexone: antagonism of the reinforcing, subjective, and physiological effects of heroin
    Maria A Sullivan
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Psychopharmacology (Berl) 189:37-46. 2006
    ..Although it is highly effective in completely antagonizing the effects of opioids, medication noncompliance is a difficult obstacle to treatment. Therefore, a sustained-release form of naltrexone may improve treatment outcome...
  26. pmc Abuse liability of prescription opioids compared to heroin in morphine-maintained heroin abusers
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 33:1179-91. 2008
    ..The abuse liabilities of fentanyl, morphine, oxycodone, and heroin, however, appear to be similar under these experimental conditions...
  27. ncbi request reprint Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial
    David McDowell
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Drug Alcohol Depend 80:209-21. 2005
    ..The aim of this study was to test the hypothesis that desipramine would be an effective treatment in cocaine abusers with current depressive disorders...
  28. ncbi request reprint Relationship between rate of infusion and reinforcing strength of oxycodone in humans
    Sandra D Comer
    Department of Psychiatry, Columbia University, New York, New York, USA
    J Opioid Manag 5:203-12. 2009
    ..Specifically, these "abuse-deterrent formulations" could prevent patients from tampering with their medications to enhance their euphoric and reinforcing effects...
  29. ncbi request reprint Reinforcing effects of oral Delta9-THC in male marijuana smokers in a laboratory choice procedure
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians, Surgeons of Columbia University, NY 10032, USA
    Psychopharmacology (Berl) 181:237-43. 2005
    ..Oral Delta-9-tetrahydrocannabinol (Delta(9)-THC; Marinol) is medically available for the treatment of nausea associated with cancer chemotherapy and for wasting syndromes related to HIV/AIDS. Little is known about its reinforcing effects...
  30. pmc Impact of in-patient research participation on subsequent heroin use patterns: implications for ethics and public health
    Perrine Roux
    Substance Use Research Center, NYSPI, Columbia University, New York, NY 10032, USA
    Addiction 107:642-9. 2012
    ..The primary objective of this study was to assess whether participation in such research alters the frequency of heroin use by non-treatment-seeking opioid-dependent volunteers after study completion...
  31. ncbi request reprint Evaluation of the reinforcing and subjective effects of heroin in combination with dextromethorphan and quinidine
    Suzanne K Vosburg
    Department of Psychiatry New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, USA
    J Opioid Manag 7:451-61. 2011
    ..Studies have suggested that the N-methyl-D-aspartate antagonist dextromethorphan may be useful in the treatment of opioid dependence...
  32. pmc Evaluation of potential sex differences in the subjective and analgesic effects of morphine in normal, healthy volunteers
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
    Psychopharmacology (Berl) 208:45-55. 2010
    ..To date, there have been few experimental studies investigating this effect in humans, and the conclusions have been equivocal...
  33. pmc Oxycodone abuse in New York City: characteristics of intravenous and intranasal users
    Jermaine D Jones
    Division on Substance Abuse, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Addict 20:190-5. 2011
    ..Additional research is needed to confirm these observed differences, yet these data may assist treatment efforts by providing information to guide targeted treatment and population-specific interventions. ..
  34. ncbi request reprint Predictors of retention in naltrexone maintenance for opioid dependence: analysis of a stage I trial
    Maria A Sullivan
    Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA
    Am J Addict 15:150-9. 2006
    ....
  35. ncbi request reprint Amantadine does not modulate reinforcing, subjective, or cardiovascular effects of cocaine in humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA
    Pharmacol Biochem Behav 76:401-7. 2003
    ..These findings, taken together with the decidedly mixed literature, suggest that amantadine (100 mg bid) will not have a role in the treatment of cocaine dependence...
  36. ncbi request reprint Sex differences and hormonal influences on response to mechanical pressure pain in humans
    William J Kowalczyk
    Division on Substance Abuse, New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    J Pain 11:330-42. 2010
    ..These results demonstrate subtle menstrual-cycle effects in NMW and OCW. Sex differences were few, with more group differences and trends emerging between OCW and men, as opposed to men and NMW...
  37. pmc Effects of research setting on observed depressive symptoms in marijuana users
    John J Mariani
    Division on Substance Abuse, New York State Psychiatric Institute, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Subst Abuse Treat 37:431-4. 2009
    ..e., treatment-seekers are more likely to be experiencing some degree of clinical distress), it is notable that treatment-seeking, and not marijuana use per se, is associated with significantly higher rates of depression...
  38. ncbi request reprint Marijuana withdrawal in humans: effects of oral THC or divalproex
    Margaret Haney
    New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 29:158-70. 2004
    ..Divalproex worsened mood and cognitive performance during marijuana abstinence. These data suggest that oral THC, but not divalproex, may be useful in the treatment of marijuana dependence...
  39. pmc Course of weight change during naltrexone versus methadone maintenance for opioid-dependent patients
    David J Mysels
    Division of Addiction Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Opioid Manag 7:47-53. 2011
    ..micro-Opiate receptor agonism has been associated with weight gain, whereas micro-antagonists have been associated with weight neutrality, or even weight loss...
  40. ncbi request reprint Impact of attention-deficit hyperactivity disorder and other psychopathology on treatment retention among cocaine abusers in a therapeutic community
    Frances Rudnick Levin
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive Unit 66, New York City, NY 10032, USA
    Addict Behav 29:1875-82. 2004
    ..Future investigations may be useful to determine whether pharmacologic or nonpharmacologic interventions might improve treatment outcome...
  41. ncbi request reprint Utility of lead-in period in cocaine dependence pharmacotherapy trials
    Adam Bisaga
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, NY, USA
    Drug Alcohol Depend 77:7-11. 2005
    ..Findings of this study suggest that route and level of cocaine use during lead-in be used as a covariate in models testing treatment effect...
  42. ncbi request reprint Pharmacotherapy for marijuana dependence: a double-blind, placebo-controlled pilot study of divalproex sodium
    Frances Rudnick Levin
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
    Am J Addict 13:21-32. 2004
    ..The design of a preliminary clinical trial should include a psychosocial/behavioral intervention emphasizing motivation and medication compliance and a placebo control group...
  43. ncbi request reprint The effect of sertraline and environmental context on treating depression and illicit substance use among methadone maintained opiate dependent patients: a controlled clinical trial
    Kenneth M Carpenter
    Division on Substance Abuse, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, 1051 Riverside Drive, Box 120, New York, NY, 10032, USA
    Drug Alcohol Depend 74:123-34. 2004
    ..They also suggest future research should examine a pharmacological treatment that is combined with a behavioral intervention targeting the accessibility of reinforcement or reducing the impact of aversive environmental interactions...
  44. ncbi request reprint Anxiety sensitivity among children of parents with anxiety disorders: a controlled high-risk study
    Salvatore Mannuzza
    NYU Child Study Center, New York University School of Medicine, New York, NY, USA
    J Anxiety Disord 16:135-48. 2002
    ..We conclude that parental anxiety or mood disorder does not predispose offspring to high anxiety sensitivity...
  45. ncbi request reprint Does marijuana use cause long-term cognitive deficits?
    Erik W Gunderson
    JAMA 287:2652; author reply 2652-3. 2002