W B Valhmu
Affiliation: Columbia University
- Regulatory activities of the 5'- and 3'-untranslated regions and promoter of the human aggrecan geneW B Valhmu
Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Columbia University, New York, New York 10032, USA
J Biol Chem 273:6196-202. 1998....
- Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expressionW B Valhmu
Department of Orthopaedic Surgery, Columbia University, New York, New York 10032, USA
Arch Biochem Biophys 353:29-36. 1998....
- Time-dependent aggrecan gene expression of articular chondrocytes in response to hyperosmotic loadingG D Palmer
Cellular Engineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA
Osteoarthritis Cartilage 9:761-70. 2001..CONCLUSION: Hyperosmotic loading regulates aggrecan gene expression and cell size in isolated chondrocytes. Osmotic regulation of gene expression is also affected by the time-varying nature of loading and the presence of serum...
- Structure of the human aggrecan gene: exon-intron organization and association with the protein domainsW B Valhmu
Department of Orthopaedic Surgery, Columbia University, New York, NY 10032, USA
Biochem J 309:535-42. 1995..The correspondence between the exon organization and the protein domains argues strongly for modular assembly of the aggrecan gene...