A Tomlinson

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough
    K Basler
    Zoologisches Institut, Universitat Zurich, Switzerland
    Genes Dev 4:728-39. 1990
  2. ncbi rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye
    A Tomlinson
    Howard Hughes Medical Institute, University of California, Berkeley 94720
    Cell 55:771-84. 1988
  3. ncbi Decoding vectorial information from a gradient: sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye
    A Tomlinson
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Development 126:5725-38. 1999
  4. ncbi Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor
    A Tomlinson
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Mol Cell 7:487-95. 2001
  5. ncbi Independent regulation of anterior/posterior and equatorial/polar polarity in the Drosophila eye; evidence for the involvement of Wnt signaling in the equatorial/polar axis
    M Wehrli
    Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Development 125:1421-32. 1998
  6. ncbi Transducing properties of Drosophila Frizzled proteins
    W R Strapps
    Department of Genetics and Development, Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 701 West 168 Street, Room 602, New York, NY 10032, USA
    Development 128:4829-35. 2001
  7. ncbi Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker
    G Campbell
    Department of Genetics and Development, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Cell 96:553-62. 1999
  8. ncbi The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila
    G Campbell
    Department of Genetics and Development, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, HHSC, Room 1120, New York, NY 10032, USA columbia edu
    Development 125:4483-93. 1998
  9. ncbi Linking Frizzled and Wnt signaling in Drosophila development
    A Tomlinson
    Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Development 124:4515-21. 1997
  10. ncbi Epithelial planar polarity in the developing Drosophila eye
    M Wehrli
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York 10032, USA
    Development 121:2451-9. 1995

Collaborators

Detail Information

Publications18

  1. ncbi Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough
    K Basler
    Zoologisches Institut, Universitat Zurich, Switzerland
    Genes Dev 4:728-39. 1990
    ..We propose that in wild type, rough functions autonomously in the specification of R2/5 photoreceptor cell identity but by itself cannot initiate neural development...
  2. ncbi rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye
    A Tomlinson
    Howard Hughes Medical Institute, University of California, Berkeley 94720
    Cell 55:771-84. 1988
    ..Taken together, our results suggest that the role of the rough gene product may be to regulate the sending of signals by photoreceptors R2 and R5 to their neighbors in the developing ommatidia...
  3. ncbi Decoding vectorial information from a gradient: sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye
    A Tomlinson
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Development 126:5725-38. 1999
    ..As a consequence of this reciprocal cell fate decision, the R4 cell moves asymmetrically relative to the R3 cell, initiating the appropriate chiral pattern of the remaining cells of the ommatidium...
  4. ncbi Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor
    A Tomlinson
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Mol Cell 7:487-95. 2001
    ....
  5. ncbi Independent regulation of anterior/posterior and equatorial/polar polarity in the Drosophila eye; evidence for the involvement of Wnt signaling in the equatorial/polar axis
    M Wehrli
    Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Development 125:1421-32. 1998
    ..Further, we show that the polarizing information acting in this equatorial/polar axis (Eq/Pl) is established in at least two steps - the activity of one signaling molecule functions to establish the graded activity of a second signal...
  6. ncbi Transducing properties of Drosophila Frizzled proteins
    W R Strapps
    Department of Genetics and Development, Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 701 West 168 Street, Room 602, New York, NY 10032, USA
    Development 128:4829-35. 2001
    ..The presence of this subset implies that the N terminus is necessary but not sufficient and suggests that the ability to transduce the polarity signal is widely distributed throughout the protein...
  7. ncbi Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker
    G Campbell
    Department of Genetics and Development, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Cell 96:553-62. 1999
    ....
  8. ncbi The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila
    G Campbell
    Department of Genetics and Development, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, HHSC, Room 1120, New York, NY 10032, USA columbia edu
    Development 125:4483-93. 1998
    ..Dll is also required for the normal development of the wing, primarily for the differentiation of the wing margin...
  9. ncbi Linking Frizzled and Wnt signaling in Drosophila development
    A Tomlinson
    Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Development 124:4515-21. 1997
    ..Taken together our results significantly strengthen the case for Fz acting in a Wnt signaling pathway in Drosophila...
  10. ncbi Epithelial planar polarity in the developing Drosophila eye
    M Wehrli
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York 10032, USA
    Development 121:2451-9. 1995
    ..We suggest that the movement of the morphogenetic wave may be causal in establishing the planar polarity of this epithelium...
  11. ncbi RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila
    G Campbell
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Development 120:2957-66. 1994
    ..This suggests that RK2 is not required for early glial determination, but rather for aspects of glial differentiation or function that are required for embryonic viability...
  12. ncbi arrow encodes an LDL-receptor-related protein essential for Wingless signalling
    M Wehrli
    University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Nature 407:527-30. 2000
    ..Thus, our data suggests a new and conserved function for this LRP subfamily in Wingless/Wnt signal reception...
  13. ncbi Dorsal-ventral signaling in the Drosophila eye
    V Papayannopoulos
    Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers, The State University, Piscataway, NJ 08854, USA
    Science 281:2031-4. 1998
    ..These observations imply that the developmental homology between Drosophila wings and vertebrate limbs extends to Drosophila eyes...
  14. ncbi A LIM-homeodomain combinatorial code for motor-neuron pathway selection
    S Thor
    Molecular Neurobiology Laboratory, The Salk Institute, San Diego, California 92186, USA
    Nature 397:76-80. 1999
    ..Our results provide evidence that lim3 and islet constitute a combinatorial code that generates distinct motor-neuron identities...
  15. ncbi Axis specification in the developing Drosophila appendage: the role of wingless, decapentaplegic, and the homeobox gene aristaless
    G Campbell
    Medical Research Council Laboratory of Molecular Biology, Cambridge, England
    Cell 74:1113-23. 1993
    ..The proximodistal axis may be specified via a mechanism involving a direct interaction between cells expressing wg, dpp, and possibly al...
  16. ncbi The dominant Drop eye mutations of Drosophila melanogaster define two loci implicated in normal eye development
    R Tearle
    Department of Biochemistry, Adelaide University, Australia
    Mol Gen Genet 244:426-34. 1994
    ....
  17. ncbi Transcriptional regulation of the Hedgehog effector CI by the zinc-finger gene combgap
    G L Campbell
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Development 127:4095-103. 2000
    ..cg encodes a putative DNA-binding protein that regulates both transcriptional activation and repression of the ci gene...
  18. ncbi Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila
    A Tomlinson
    Howard Hughes Medical Institute, University of California, Berkeley 94720
    Cell 51:143-50. 1987
    ..The protein is mostly localized at the apices of the cells, in microvilli, but is also found deeper in the tissue where certain cells contact the R8 cell. This finding suggests that R8 expresses a ligand for the sevenless protein...