Andrew F Teich
Affiliation: Columbia University
- Comparison among some models of orientation selectivityAndrew F Teich
Center for Neurobiology and Behavior, Mahoney Center for Brain and Behaviour Research, and Department of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA
J Neurophysiol 96:404-19. 2006..Because orientation-tuned V1 cells show a continuum of simple- to complex-cell behavior, the MRM provides the best description of V1 data...
- A reliable way to detect endogenous murine β-amyloidAndrew F Teich
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, New York, United States of America
PLoS ONE 8:e55647. 2013..Here, we examine the background signal of several murine β-amyloid ELISAs, and conclude that the majority of the background is from non-APP derived proteins. Most importantly, we identify ELISAs that eliminate this background signal...
- Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant?Andrew F Teich
Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, PH15 124, New York, NY 10032, USA
Biochem J 446:165-77. 2012....
- V1 orientation plasticity is explained by broadly tuned feedforward inputs and intracortical sharpeningAndrew F Teich
Department of Pathology, Columbia University, New York, New York 10032, USA
Vis Neurosci 27:57-73. 2010..We predict that the plastic properties must be absent for cells whose orientation tuning arises from a feedforward mechanism...
- Learning and adaptation in a recurrent model of V1 orientation selectivityAndrew F Teich
Center for Neurobiology and Behavior and Department of Physiology and Cellular Biophysics, Columbia University, New York, New York 10032, USA
J Neurophysiol 89:2086-100. 2003..Instead, human adaptation studies can be better accounted for by the learning data from behaving animals. Our work suggests that adaptation in behaving subjects may be viewed as a short-term form of learning...
- 5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulationGakuji Hashimoto
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
J Alzheimers Dis 32:437-45. 2012..Taken all together, these experiments demonstrate that 5-HT4 receptor stimulation induces expression of MMP-9 which cleaves AβPP through α-secretase-like activity, leading to an increase of sAβPPα levels and a reduction of Aβ load...