David A Talmage

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Back signaling by the Nrg-1 intracellular domain
    Jianxin Bao
    Institute of Human Nutrition, 701 West 168th St, 5 503 New York, NY 10032, USA
    J Cell Biol 161:1133-41. 2003
  2. pmc Presynaptic type III neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axons
    Melissa L Hancock
    Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, NY 10032, USA
    J Cell Biol 181:511-21. 2008
  3. pmc Retinoids arrest breast cancer cell proliferation: retinoic acid selectively reduces the duration of receptor tyrosine kinase signaling
    Ann P Tighe
    Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Exp Cell Res 301:147-57. 2004
  4. pmc Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation
    Guillermina López-Bendito
    Instituto de Neurociencias de Alicante, CSIC and Universidad Miguel Hernandez, 03550 Sant Joan d Alacant, Spain
    Cell 125:127-42. 2006
  5. pmc Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit
    Young Hwan Jo
    Department of Pathology and Cell Biology, Center for Neurobiology and Behavior, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Neuron 48:1055-66. 2005
  6. ncbi Neurobiology: new order for thought disorders
    Lorna W Role
    Nature 448:263-5. 2007
  7. pmc Mechanisms of neuregulin action
    David A Talmage
    Institute of Human Nutrition and Department of Pediatrics, Columbia University Medical Center, 630 West 168th Street, New York, NY 10024, USA
    Novartis Found Symp 289:74-84; discussion 84-93. 2008
  8. pmc Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
    Ying Jiun J Chen
    Department of Cell Biology and Pathology, School of Pubic Health, Columbia University, New York, New York, USA
    J Neurosci 28:6872-83. 2008
  9. pmc Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors
    Chongbo Zhong
    Department of Neurosciences, Columbia University, New York, New York 10032, USA
    J Neurosci 28:9111-6. 2008

Collaborators

  • Jianxin Bao
  • Lorna W Role
  • Ying Jiun J Chen
  • Chongbo Zhong
  • Melissa L Hancock
  • Guillermina López-Bendito
  • Young Hwan Jo
  • Ann P Tighe
  • Marjolijn Mertz
  • CHUANG DU
  • Melissa Hancock
  • Jay A Gingrich
  • Gorazd Rosoklija
  • Andrew J Dwork
  • Scott Small
  • Nicole Lewandowski
  • Scott Schobel
  • Madeleine A Johnson
  • Michael D Lieberman
  • Sarah E Canetta
  • Ruei Che Liu
  • Holly Moore
  • Rose E Goodchild
  • Franck Bielle
  • Juan Antonio Sanchez
  • Patrick Charnay
  • Oscar Marin
  • Alistair N Garratt
  • Aline Cautinat
  • Sonia Garel
  • Nuria Flames
  • Streamson C Chua

Detail Information

Publications9

  1. pmc Back signaling by the Nrg-1 intracellular domain
    Jianxin Bao
    Institute of Human Nutrition, 701 West 168th St, 5 503 New York, NY 10032, USA
    J Cell Biol 161:1133-41. 2003
    ..Thus, regulated proteolytic processing of Nrg-1 results in retrograde signaling that appears to mediate contact and activity-dependent survival of Nrg-1-expressing neurons...
  2. pmc Presynaptic type III neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axons
    Melissa L Hancock
    Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, NY 10032, USA
    J Cell Biol 181:511-21. 2008
    ....
  3. pmc Retinoids arrest breast cancer cell proliferation: retinoic acid selectively reduces the duration of receptor tyrosine kinase signaling
    Ann P Tighe
    Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Exp Cell Res 301:147-57. 2004
    ..These results indicate that RA-induced target genes, particularly PKCalpha, prevent sustained growth factor signaling, uncoupling activated receptor tyrosine kinases and nuclear targets that are required for cell cycle progression...
  4. pmc Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation
    Guillermina López-Bendito
    Instituto de Neurociencias de Alicante, CSIC and Universidad Miguel Hernandez, 03550 Sant Joan d Alacant, Spain
    Cell 125:127-42. 2006
    ..These results show that neuronal tangential migration constitutes a novel mechanism to control the timely arrangement of guidance cues required for axonal tract formation in the mammalian brain...
  5. pmc Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit
    Young Hwan Jo
    Department of Pathology and Cell Biology, Center for Neurobiology and Behavior, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Neuron 48:1055-66. 2005
    ..Our data provide direct electrophysiological support for the involvement of endocannabinoids and leptin as modulators of hypothalamic circuits underlying motivational aspects of feeding behavior...
  6. ncbi Neurobiology: new order for thought disorders
    Lorna W Role
    Nature 448:263-5. 2007
  7. pmc Mechanisms of neuregulin action
    David A Talmage
    Institute of Human Nutrition and Department of Pediatrics, Columbia University Medical Center, 630 West 168th Street, New York, NY 10024, USA
    Novartis Found Symp 289:74-84; discussion 84-93. 2008
    ..Of particular interest to this discussion are findings linking deficits in Nrg1-ErbB4 signalling to perturbations of synaptic transmission, myelination, and the survival of particular sets of neurons and glia...
  8. pmc Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
    Ying Jiun J Chen
    Department of Cell Biology and Pathology, School of Pubic Health, Columbia University, New York, New York, USA
    J Neurosci 28:6872-83. 2008
    ..Our findings demonstrate a role of type III Nrg1 signaling in the maintenance of corticostriatal components and in the neural circuits involved in sensorimotor gating and short-term memory...
  9. pmc Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors
    Chongbo Zhong
    Department of Neurosciences, Columbia University, New York, New York 10032, USA
    J Neurosci 28:9111-6. 2008
    ..Thus, selective alteration of the level of presynaptic type III Nrg1 dramatically affects the modulation of glutamatergic transmission at ventral hippocampal to nucleus accumbens synapses...