Peter S Talbot

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint 11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons
    Peter S Talbot
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    J Nucl Med 46:484-94. 2005
  2. ncbi request reprint The molecular neuroimaging of anxiety disorders
    Peter S Talbot
    Division of Functional Brain Mapping, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 31, New York, NY 10032, USA
    Curr Psychiatry Rep 6:274-9. 2004
  3. ncbi request reprint Effects of reduced endogenous 5-HT on the in vivo binding of the serotonin transporter radioligand 11C-DASB in healthy humans
    Peter S Talbot
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
    Synapse 55:164-75. 2005
  4. ncbi request reprint In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]-raclopride
    Rajesh Narendran
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Synapse 52:188-208. 2004
  5. ncbi request reprint Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans
    W Gordon Frankle
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, New York, New York, USA
    J Nucl Med 45:682-94. 2004
  6. ncbi request reprint Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652
    W Gordon Frankle
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, 1051 Riverside Dr, Box 31, New York, NY 10032, USA
    Am J Psychiatry 162:915-23. 2005
  7. ncbi request reprint Altered prefrontal dopaminergic function in chronic recreational ketamine users
    Rajesh Narendran
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Psychiatry 162:2352-9. 2005
  8. ncbi request reprint Effect of amphetamine on [(18)F]fallypride in vivo binding to D(2) receptors in striatal and extrastriatal regions of the primate brain: Single bolus and bolus plus constant infusion studies
    Mark Slifstein
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, New York 10032, USA
    Synapse 54:46-63. 2004
  9. pmc Sustained recreational use of ecstasy is associated with altered pre and postsynaptic markers of serotonin transmission in neocortical areas: a PET study with [¹¹C]DASB and [¹¹C]MDL 100907
    Nina Bl Urban
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Neuropsychopharmacology 37:1465-73. 2012
  10. ncbi request reprint Quantitative analysis of (-)-N-(11)C-propyl-norapomorphine in vivo binding in nonhuman primates
    Dah Ren Hwang
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nucl Med 45:338-46. 2004

Detail Information

Publications15

  1. ncbi request reprint 11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons
    Peter S Talbot
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    J Nucl Med 46:484-94. 2005
    ..The (-)-isomer, GR103545, is the active enantiomer of GR89696. The aim of this study was to characterize the potential of 11C-GR103545 to image kappa-OR in vivo with PET...
  2. ncbi request reprint The molecular neuroimaging of anxiety disorders
    Peter S Talbot
    Division of Functional Brain Mapping, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 31, New York, NY 10032, USA
    Curr Psychiatry Rep 6:274-9. 2004
    ..Recent findings have extended the knowledge of hippocampal abnormalities in post-traumatic stress disorder, and have highlighted the complexity of the association between cortisol and the hippocampus in this disorder...
  3. ncbi request reprint Effects of reduced endogenous 5-HT on the in vivo binding of the serotonin transporter radioligand 11C-DASB in healthy humans
    Peter S Talbot
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
    Synapse 55:164-75. 2005
    ..These results suggest that (11)C-DASB in vivo binding is not affected by reductions in endogenous 5-HT...
  4. ncbi request reprint In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]-raclopride
    Rajesh Narendran
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Synapse 52:188-208. 2004
    ..In conclusion, [11C]NPA might provide a superior radiotracer to probe presynaptic DA function with PET in health and disease...
  5. ncbi request reprint Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans
    W Gordon Frankle
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, New York, New York, USA
    J Nucl Med 45:682-94. 2004
    ..The purpose of this study was to compare these 2 agents in healthy humans...
  6. ncbi request reprint Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652
    W Gordon Frankle
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, 1051 Riverside Dr, Box 31, New York, NY 10032, USA
    Am J Psychiatry 162:915-23. 2005
    ..This study evaluated regional serotonin transporter distribution in the brain of individuals with impulsive aggression by using positron emission tomography (PET) with the serotonin transporter PET radiotracer [(11)C]McN 5652...
  7. ncbi request reprint Altered prefrontal dopaminergic function in chronic recreational ketamine users
    Rajesh Narendran
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Psychiatry 162:2352-9. 2005
    ..In this study, dopamine D1 receptor availability was assessed by using positron emission tomography and the selective D1 receptor radioligand [11C]NNC 112 in a group of 14 recreational chronic ketamine users and matched healthy subjects...
  8. ncbi request reprint Effect of amphetamine on [(18)F]fallypride in vivo binding to D(2) receptors in striatal and extrastriatal regions of the primate brain: Single bolus and bolus plus constant infusion studies
    Mark Slifstein
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, New York 10032, USA
    Synapse 54:46-63. 2004
    ....
  9. pmc Sustained recreational use of ecstasy is associated with altered pre and postsynaptic markers of serotonin transmission in neocortical areas: a PET study with [¹¹C]DASB and [¹¹C]MDL 100907
    Nina Bl Urban
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Neuropsychopharmacology 37:1465-73. 2012
    ..Alterations in mood, cognition, and impulse control associated with these changes might contribute to sustain MDMA use. The reversibility of these changes upon abstinence remains to be firmly established...
  10. ncbi request reprint Quantitative analysis of (-)-N-(11)C-propyl-norapomorphine in vivo binding in nonhuman primates
    Dah Ren Hwang
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nucl Med 45:338-46. 2004
    ..The goal of this study was to develop and evaluate analytic strategies to derive in vivo (11)C-NPA binding parameters...
  11. pmc Extended characterisation of the serotonin 2A (5-HT2A) receptor-selective PET radiotracer 11C-MDL100907 in humans: quantitative analysis, test-retest reproducibility, and vulnerability to endogenous 5-HT tone
    Peter S Talbot
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Neuroimage 59:271-85. 2012
    ..We present an extended characterisation in healthy human subjects...
  12. ncbi request reprint Neuroreceptor imaging in psychiatry: theory and applications
    W Gordon Frankle
    Departments of Psychiatry, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, New York 10032, USA
    Int Rev Neurobiol 67:385-440. 2005
  13. ncbi request reprint The role of in vivo molecular imaging with PET and SPECT in the elucidation of psychiatric drug action and new drug development
    Peter S Talbot
    Department of Psychiatry and Radiology, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, NY 10032, USA
    Eur Neuropsychopharmacol 12:503-11. 2002
    ..In therapeutic drug development, these techniques may be used to assess receptor occupancy profiles, likely drug dosages and dosing intervals which cannot be reliably assessed in humans by other methods...
  14. ncbi request reprint Anterior cingulate and subgenual prefrontal blood flow changes following tryptophan depletion in healthy males
    Peter S Talbot
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, UK
    Neuropsychopharmacology 31:1757-67. 2006
    ..The results therefore suggest that the dissociation between affective and cognitive consequences of RTD may possibly be attributable to differential effects of reduced 5-HT on these neural systems...
  15. ncbi request reprint Rapid tryptophan depletion improves decision-making cognition in healthy humans without affecting reversal learning or set shifting
    Peter S Talbot
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, UK
    Neuropsychopharmacology 31:1519-25. 2006
    ....