Research Topics
| Maria SullivanSummaryAffiliation: Columbia University Country: USA Publications
Research Grants
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Detail Information
Publications
Abuse liability of prescription opioids compared to heroin in morphine-maintained heroin abusersSandra D Comer
Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Neuropsychopharmacology 33:1179-91. 2008..The abuse liabilities of fentanyl, morphine, oxycodone, and heroin, however, appear to be similar under these experimental conditions...- Predictors of retention in naltrexone maintenance for opioid dependence: analysis of a stage I trialMaria A Sullivan
Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA
Am J Addict 15:150-9. 2006.... - Attention deficit/hyperactivity disorder and substance abuse. Diagnostic and therapeutic considerationsM A Sullivan
Department of Psychiatry, Columbia Presbyterian Medical Center, New York, NY 10032, USA
Ann N Y Acad Sci 931:251-70. 2001..We suggest promising areas of focus for clinical research trials targeting the subpopulation of substance abusers with concurrent ADHD... - Management of relapse in naltrexone maintenance for heroin dependenceMaria A Sullivan
College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Drug Alcohol Depend 91:289-92. 2007..Time retained in treatment was examined as a function of whether lapses to opioid use occurred while adherent to naltrexone (blocked use), or after having missed naltrexone doses (unblocked)... 
Uses of coercion in addiction treatment: clinical aspectsMaria A Sullivan
Columbia College of Physicians and Surgeons New York State Psychiatric Institute, New York, NY 10032, USA
Am J Addict 17:36-47. 2008..The philosophical, historical, and societal aspects of coerced treatment are considered...- Current perspectives on smoking cessation among substance abusersMaria A Sullivan
Department of Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute at Columbia University, NY 10032, USA
Curr Psychiatry Rep 4:388-96. 2002..Smoking cessation is indicated for substance dependent persons already in recovery and may protect against relapse to the illicit drug of abuse... 
Comparison of substance use milestones in cannabis- and cocaine-dependent patientsJonathan T Horey
Division on Substance Abuse, New York Psychiatric Institute, New York, New York 10022, USA
J Addict Dis 31:60-6. 2012..To compare the progression of substance use milestones between cocaine- and cannabis-dependent patients...- Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependenceWilfrid Noel Raby
Division on Substance Abuse, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
Am J Addict 18:301-8. 2009..Experimental studies are needed to directly test the hypothesis that cannabinoid agonists exert a beneficial pharmacological effect on naltrexone maintenance and to understand the mechanism... - Comparison of clinical trial recruitment populations: treatment-seeking characteristics of opioid-, cocaine-, and cannabis-using participantsJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, New York, NY 10032, USA
J Subst Abuse Treat 40:426-30. 2011..These results have implications for clinical trial recruitment and public health efforts directed at encouraging cannabis-dependent individuals to seek treatment... - Abuse liability of oxycodone as a function of pain and drug use historyS D Comer
Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
Drug Alcohol Depend 109:130-8. 2010..These data suggest that an assessment of the reinforcing effects of opioids may be a sensitive method for differentiating opioid abusers from non-abusers... - Advances in non-nicotine pharmacotherapy for smoking cessationL S Covey
New York State Psychiatric Institute, New York 10032, USA
Drugs 59:17-31. 2000..Thus, available evidence indicates that non-nicotine drug treatments offer a promising panoply of therapeutic strategies for the addicted smoker... - Concurrent substance use and outcome in combined behavioral and naltrexone therapy for opiate dependenceS H Church
New York State Psychiatric Institute, Substance Treatment and Research Service, New York 10032, USA
Am J Drug Alcohol Abuse 27:441-52. 2001..Further research is needed to identify the optimal therapeutic stance toward other drug use during treatment for opiate dependence... - Injectable, sustained-release naltrexone for the treatment of opioid dependence: a randomized, placebo-controlled trialSandra D Comer
Division on Substance Abuse, New York State Psychiatric Institute, and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York 10032, USA
Arch Gen Psychiatry 63:210-8. 2006..Oral naltrexone can completely antagonize the effects produced by opioid agonists. However, poor compliance with naltrexone has been a major obstacle to the effective treatment of opioid dependence... - Nicotine dependence: the role for antidepressants and anxiolyticsMaria A Sullivan
New York State Psychiatric Institute, New York 10032, USA
Curr Opin Investig Drugs 3:262-71. 2002..The norepinephrinergic effects of nicotine may account for increased attentiveness and improved performance in repetitive tasks, while its anxiolytic effects are likely mediated through GABA and the endorphins... - Behavioral naltrexone therapy: an integrated treatment for opiate dependenceJami L Rothenberg
The New York State Psychiatric Institute, Division on Substance Abuse, Substance Treatment and Research Service, 1051 Riverside Drive, New York, NY 10032, USA
J Subst Abuse Treat 23:351-60. 2002..Thus, attrition continues to be a serious problem for naltrexone maintenance, although further efforts to develop interventions such as BNT are warranted... - Response: providing relief, avoiding euphoriaDennis Paul
Addict Sci Clin Pract 4:26-7. 2008 - Dextromethorphan and quinidine combination for heroin detoxificationEvaristo Akerele
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
Am J Addict 17:176-80. 2008..Future studies should examine dextromethorphan as an adjunct to other anti-withdrawal medications and focus more on the relationship between dextrorphan levels and withdrawal suppression... - Treatment of depression in patients with opiate dependenceEdward V Nunes
New York State Psychiatric Institute, and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Biol Psychiatry 56:793-802. 2004..Research is needed on such integrated models of care and treatment algorithms to determine their efficacy and cost effectiveness... - Sustained-release naltrexone: novel treatment for opioid dependenceSandra D Comer
College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, Department of Psychiatry, Unit 120, New York, NY 10032, USA
Expert Opin Investig Drugs 16:1285-94. 2007..The present paper describes the development of sustained-release naltrexone formulations and discusses the clinical issues associated with their use in treating opioid dependence... - Reducing hospital presentations for opioid overdose in patients treated with sustained release naltrexone implantsGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
Drug Alcohol Depend 79:351-7. 2005..However, given the high prevalence of poly-substance use among dependent heroin users, programs offering this type of treatment should also focus on preventing, detecting and managing poly-substance use... - Memantine produces modest reductions in heroin-induced subjective responses in human research volunteersSandra D Comer
Division on Substance Abuse, New York State Psychiatric Institute, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
Psychopharmacology (Berl) 193:235-45. 2007..Previous studies have demonstrated an interaction between opioids and noncompetitive antagonists at N-methyl-D: -aspartate (NMDA) receptors, but few studies have examined the utility of these medications for treating opioid dependence... - Socially sanctioned coercion mechanisms for addiction treatmentEdgar P Nace
University of Texas, Southwestern Medical School, Dallas, TX, USA
Am J Addict 16:15-23. 2007..This unmet need, coupled with the evidence for positive clinical outcomes, highlights the call for implementing socially sanctioned mechanisms of coercion... - Effects of alternative reinforcer and craving on the choice to smoke cigarettes in the laboratoryAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA
Hum Psychopharmacol 22:41-7. 2007..This paradigm models the motivational component associated with choice to smoke and could be used to evaluate the effects of pharmacological and behavioral interventions to decrease cigarette smoking... - Comparison of intravenous buprenorphine and methadone self-administration by recently detoxified heroin-dependent individualsSandra D Comer
The New York State Psychiatric Institute and College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
J Pharmacol Exp Ther 315:1320-30. 2005..These results demonstrate that under these experimental conditions, buprenorphine and methadone were equally effective in producing reinforcing and subjective effects... - Depot naltrexone: antagonism of the reinforcing, subjective, and physiological effects of heroinMaria A Sullivan
Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
Psychopharmacology (Berl) 189:37-46. 2006..CONCLUSIONS: The present results extend our previous findings by showing that the reinforcing effects of heroin were reduced for 4-5 weeks after administration of 384 mg depot naltrexone... - New-onset mania and psychosis following heroin detoxification and naltrexone maintenanceMaria A Sullivan
Am J Addict 14:486-7. 2005 - Behavioral therapy to augment oral naltrexone for opioid dependence: a ceiling on effectiveness?Edward V Nunes
New York State Psychiatric Institute, Division on Substance Abuse, New York, New York 10032, USA
Am J Drug Alcohol Abuse 32:503-17. 2006..Future research should consider combinations of behavioral methods with new long-acting injectable or implantable naltrexone formulations... - Sex differences and hormonal influences on response to cold pressor pain in humansWilliam J Kowalczyk
Division on Substance Abuse, New York State Psychiatric Institute, and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Pain 7:151-60. 2006....
Research Grants
- Predictors of Relapse to Prescription Opioid Abuse Among Pain PatientsMaria Sullivan; Fiscal Year: 2009..These questions are of immediate clinical relevance to the treatment of chronic pain with opioid therapy. ..
- Predictors of Relapse to Prescription Opioid Abuse Among Pain PatientsMaria Sullivan; Fiscal Year: 2007..These questions are of immediate clinical relevance to the treatment of chronic pain with opioid therapy. ..
- Predictors of Relapse to Prescription Opioid Abuse Among Pain PatientsMaria A Sullivan; Fiscal Year: 2010..These questions are of immediate clinical relevance to the treatment of chronic pain with opioid therapy. ..