Research Topics
| E SirisSummaryAffiliation: Columbia University Country: USA Publications
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Publications
What's in a name? What constitutes the clinical diagnosis of osteoporosis?E S Siris
Toni Stabile Osteoporosis Center and Metabolic Bone Diseases Program, Division of Endocrinology, Department of Medicine, Columbia University Medical Center, 180 Fort Washington Avenue, New York, NY 10032, USA
Osteoporos Int 23:2093-7. 2012....
Assessment of 10-year absolute fracture risk: a new paradigm with worldwide applicationE Siris
Osteoporos Int 19:383-4. 2008
The effect of age and bone mineral density on the absolute, excess, and relative risk of fracture in postmenopausal women aged 50-99: results from the National Osteoporosis Risk Assessment (NORA)E S Siris
College of Physicians and Surgeons, Columbia University, New York, NY, USA
Osteoporos Int 17:565-74. 2006....- Patients with hip fracture: what can be improved?Ethel S Siris
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032 3702, USA
Bone 38:S8-12. 2006..Appropriate risk factor assessment and use of current intervention strategies should markedly reduce the numbers of new fractures... - Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databasesEthel S Siris
Toni Stabile Osteoporosis Center, Department of Medicine, Columbia University Medical Center, Harkness Pavilion 9 964, 180 Fort Washington Ave, New York, NY 10032, USA
Mayo Clin Proc 81:1013-22. 2006..To characterize the relationships between adherence (complance and persistence) to bisphosphonate therapy and risk of specific fracture types in postmenopausal women... - Medical management of Paget's disease of bone: indications for treatment and review of current therapiesEthel S Siris
Department of Medicine, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York, USA
J Bone Miner Res 21:P94-8. 2006..It is not known whether resistance to other bisphosphonates in Paget's disease occurs... - Enhanced prediction of fracture risk combining vertebral fracture status and BMDE S Siris
Metabolic Bone Disease Program, Toni Stabile Osteoporosis Center, Columbia University Medical Center, New York, NY 10032 3784, USA
Osteoporos Int 18:761-70. 2007..In this analysis, for any given BMD T-score, incident fracture risk varied up to twelve fold when information regarding prevalent radiographic vertebral fracture status was considered... - Effects of risedronate on fracture risk in postmenopausal women with osteopeniaE S Siris
Toni Stabile Osteoporosis Center, Columbia University Medical Center, New York, NY, 10032, USA
Osteoporos Int 19:681-6. 2008..e., T-scores between -1 and -2.5). Risedronate reduced the fracture risk by 73% (p = 0.023) in this population of women with low femoral neck bone mass and no prevalent vertebral fractures... - Impact of osteoporosis treatment adherence on fracture rates in North America and EuropeEthel S Siris
Toni Stabile Osteoporosis Center, Department of Medicine, Columbia University Medical Center, New York, New York 10032, USA
Am J Med 122:S3-13. 2009.... - Primary care use of FRAX: absolute fracture risk assessment in postmenopausal women and older menEthel S Siris
Osteoporosis Center, Columbia University Medical Center, 180 Fort Washington Avenue, New York, NY 10032, USA
Postgrad Med 122:82-90. 2010..FRAX has the potential to demystify fracture risk assessment in primary care for patients with low bone density, directing clinical fracture prevention strategies to those who can benefit most... - Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW)E S Siris
Department of Medicine, Columbia University Medical Center, 180 Fort Washington Avenue, Harkness Pavilion 9 964, New York, NY 10032, USA
Osteoporos Int 22:27-35. 2011..Most postmenopausal women with risk factors failed to appreciate their actual risk for fracture. Improved education about osteoporosis risk factors is needed... - Estimating bisphosphonate use and fracture reduction among US women aged 45 years and older, 2001-2008Ethel S Siris
Department of Medicine, Toni Stabile Osteoporosis Center, Columbia University Medical Center, New York, NY 10032, USA
J Bone Miner Res 26:3-11. 2011..Treatment with oral bisphosphonates has prevented a substantial number of fractures. Even more fractures would have been prevented if recognition, treatment, and compliance were improved... - Skeletal effects of raloxifene after 8 years: results from the continuing outcomes relevant to Evista (CORE) studyEthel S Siris
Toni Stabile Osteoporosis Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Bone Miner Res 20:1514-24. 2005..CORE had limitations for assessing fracture risk. In a subset of 386 women, 7 years of raloxifene treatment significantly increased lumbar spine and femoral neck BMD compared from the baseline of MORE... - Bone mineral density thresholds for pharmacological intervention to prevent fracturesEthel S Siris
Metabolic Bone Disease Program, Toni Stabile Osteoporosis Center, Columbia Presbyterian Medical Center, 180 Fort Washington Avenue, New York, NY 10032 3784, USA
Arch Intern Med 164:1108-12. 2004.... - Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk AssessmentE S Siris
Toni Stabile Osteoporosis Center, Columbia Presbyterian Medical Center, 180 Fort Washington Ave, New York, NY 10032 3784, USA
JAMA 286:2815-22. 2001..Large segments of the population at risk for osteoporosis and fracture have not been evaluated, and the usefulness of peripheral measurements for short-term prediction of fracture risk is uncertain... - Pins and plaster aren't enough: a call for the evaluation and treatment of patients with osteoporotic fracturesEthel S Siris
Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
J Clin Endocrinol Metab 88:3482-6. 2003..A call to action is necessary to reduce the human and economic costs associated with this serious and treatable disease... - Effects of raloxifene on fracture severity in postmenopausal women with osteoporosis: results from the MORE study. Multiple Outcomes of Raloxifene EvaluationE Siris
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Osteoporos Int 13:907-13. 2002.... - Predictive value of low BMD for 1-year fracture outcomes is similar for postmenopausal women ages 50-64 and 65 and Older: results from the National Osteoporosis Risk Assessment (NORA)Ethel S Siris
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032 3784, USA
J Bone Miner Res 19:1215-20. 2004..In a large cohort of postmenopausal women > or =50 years of age, we found the relationship of BMD measured at peripheral sites and subsequent 1-year fracture risk to be similar between women <65 and those > or =65 years of age... - Comparison of bone mineral density of the phalanges, lumbar spine, hip, and forearm for the assessment of osteoporosis in postmenopausal womenJ E Mulder
Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
J Clin Densitom 3:373-81. 2000..Within the limitations of single-site measurements, BMD measured by ADXA has adequate sensitivity to identify women with low BMD at the femoral neck, if an appropriate T-score criterion is used... - Assessment of inpatient fragility fracture education and outpatient follow-up at an urban tertiary care institutionRichard S Yoon
Department of Orthopaedic Surgery, Columbia University, New York 10032, USA
Endocr Pract 14:58-68. 2008..To assess the impact of inpatient fragility fracture education on follow-up care at an urban tertiary care center with a multidisciplinary inpatient education and follow-up initiative... - An approach to identifying osteopenic women at increased short-term risk of fracturePaul D Miller
Colorado Center for Bone Research, 3190 S. Wadsworth Boulevard, Suite 250, Lakewood, CO 80227, USA
Arch Intern Med 164:1113-20. 2004..5 to -1.0 who are at increased risk of fracture within 12 months. It can be used in clinical practice to guide assessment and treatment decisions... - Rapid loss of hip fracture protection after estrogen cessation: evidence from the National Osteoporosis Risk AssessmentJohn Yates
Merck and Company, Inc, Upper Gwynedd, Pennsylvania, USA
Obstet Gynecol 103:440-6. 2004..The objective of this study was to evaluate the association between HT cessation and hip fracture risk... - Impact of recent fracture on health-related quality of life in postmenopausal womenSusan K Brenneman
Outcomes Research and Management, Merck and Co, Inc WP39 170, West Point, PA 19486, USA
J Bone Miner Res 21:809-16. 2006..The impact of spine, hip, or rib fractures was greater than that of wrist fractures in both age groups... - Recency and duration of postmenopausal hormone therapy: effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) studyElizabeth Barrett-Connor
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
Menopause 10:412-9. 2003.... - Osteoporosis and fracture risk in women of different ethnic groupsElizabeth Barrett-Connor
Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0607, USA
J Bone Miner Res 20:185-94. 2005..Weight explained differences in BMD, except among blacks, who had the highest BMD. One SD decrease in BMD predicted a 50% increased fracture risk in each group. Despite similar relative risks, absolute fracture rates differed... - Prediction of fracture risk in postmenopausal white women with peripheral bone densitometry: evidence from the National Osteoporosis Risk AssessmentPaul D Miller
Colorado Center for Bone Research, Lakewood, Colorado 80227, USA
J Bone Miner Res 17:2222-30. 2002..We conclude that low BMD found by peripheral technologies, regardless of the site measured, is associated with at least a twofold increased risk of fracture within 1 year, even at skeletal sites other than the one measured... - NICE recommendations for the prevention of osteoporotic fractures in postmenopausal womenPierre D Delmas
INSERM Research Unit 831 and University of Lyon, Hopital E. Herriot, Pavillon F, 69437 Lyon Cedex 03, France
Bone 42:16-8. 2008 - Familial aggregation of Paget's disease of bone. 1991Ethel S Siris
J Bone Miner Res 20:542-7. 2005 - Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapyMichael F Holick
Boston University School of Medicine, 715 Albany Street, M1013, Boston, Massachusetts 02118, USA
J Clin Endocrinol Metab 90:3215-24. 2005..To evaluate serum 25-hydroxyvitamin D [25(OH)D] concentrations and factors related to vitamin D inadequacy in postmenopausal North American women receiving therapy to treat or prevent osteoporosis...