Research Topics
| Helen Blair SimpsonSummaryAffiliation: Columbia University Country: USA Publications
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Detail Information
Publications
Treatment of obsessive-compulsive disorder complicated by comorbid eating disordersH Blair Simpson
Department of Psychiatry, Columbia University, New York, USA
Cogn Behav Ther 42:64-76. 2013..Conclusion: Simultaneous treatment of OCD and eating disorders using a multimodal approach that emphasizes ERP techniques for both OCD and eating disorders can be an effective treatment strategy for these complex cases...
Investigation of cortical glutamate-glutamine and γ-aminobutyric acid in obsessive-compulsive disorder by proton magnetic resonance spectroscopyHELEN B SIMPSON
Department of Psychiatry at Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Neuropsychopharmacology 37:2684-92. 2012..However, they may have decreased MPFC GABA levels. How GABA abnormalities might contribute to corticostriatal dysfunction in OCD deserves further study...
Serotonin 2A receptors in obsessive-compulsive disorder: a positron emission tomography study with [11C]MDL 100907Helen Blair Simpson
Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
Biol Psychiatry 70:897-904. 2011..This study used positron emission tomography with the radioligand [11C]MDL 100907 to examine whether the distribution of serotonin 2A (5-HT(2A)) receptors is altered in OCD...
Patient adherence predicts outcome from cognitive behavioral therapy in obsessive-compulsive disorderHelen Blair Simpson
Columbia University New York State Psychiatric Institute, 1051 Riverside Drive, Unit 69, New York, NY 10032, USA
J Consult Clin Psychol 79:247-52. 2011..To examine the effects of patient adherence on outcome from exposure and response prevention (EX/RP) therapy in adults with obsessive-compulsive disorder (OCD)...
A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorderHelen Blair Simpson
Anxiety Disorders Clinic, New York State Psychiatric Institute, Unit 69, 1051 Riverside Dr, New York, NY 10032, USA
Am J Psychiatry 165:621-30. 2008..The purpose of this study was to examine the effects of augmenting SRIs with exposure and ritual prevention, an established cognitive-behavioral therapy (CBT) for OCD...
Escitalopram for persistent symptoms of generalized anxiety disorder after CBT: a pilot studyFranklin R Schneier
Anxiety Disorders Clinic, New York State Psychiatric Institute, New York, NY 10032, USA
J Nerv Ment Dis 198:458-61. 2010..Escitalopram may benefit GAD patients with clinically significant symptoms after CBT and merits further study under controlled conditions in a larger sample...
Adding motivational interviewing to exposure and ritual prevention for obsessive-compulsive disorder: an open pilot trialHelen Blair Simpson
Anxiety Disorders Clinic, New York State Psychiatric Institute, New York, NY, USA
Cogn Behav Ther 37:38-49. 2008..Challenges in combining these treatments and maintaining the integrity of each as well as limitations of the study are discussed...
Response versus remission in obsessive-compulsive disorderHelen Blair Simpson
New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 67:269-76. 2006..To investigate rates of response and remission in adults with obsessive-compulsive disorder (OCD) after 12 weeks of evidence-based treatment...
Treatment of obsessive-compulsive disorder by U.S. psychiatristsCarlos Blanco
Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 67:946-51. 2006..To examine the treatment of obsessive-compulsive disorder (OCD) by a nationally representative sample of psychiatrists...
Standard criteria for relapse are needed in obsessive-compulsive disorderHelen Blair Simpson
Anxiety Disorders Clinic, New York State Psychiatric Institute, New York, New York 10032, USA
Depress Anxiety 21:1-8. 2005..Standard criteria for relapse are needed in OCD to facilitate comparisons between studies (enabling better treatment guidelines) and to advance research on mechanisms of relapse and relapse prevention...
Patient preferences for obsessive-compulsive disorder treatmentSapana R Patel
Columbia University, Department of Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 71:1434-9. 2010..To explore preferences for the treatment of obsessive-compulsive disorder (OCD). We hypothesized that OCD patients will select a combination of medication and psychotherapy as their most preferred choice overall...
Statistical choices can affect inferences about treatment efficacy: a case study from obsessive-compulsive disorder researchHelen Blair Simpson
Department of Psychiatry, Columbia University, USA
J Psychiatr Res 42:631-8. 2008..The use of appropriate statistical methods in psychiatric trials can advance public health by ensuring that valid inferences are made about treatment efficacy...
Development of a patient adherence scale for exposure and response prevention therapyHelen Blair Simpson
Anxiety Disorders Clinic, New York Psychiatric Institute, Unit 69, 1051 Riverside Drive, New York, NY 10032, USA
Behav Ther 41:30-7. 2010..Future research will need to test the scale's reliability and validity in a larger sample of patients over the course of treatment...
Challenges using motivational interviewing as an adjunct to exposure therapy for obsessive-compulsive disorderHelen Blair Simpson
New York State Psychiatric Institute, New York, NY, USA
Behav Res Ther 48:941-8. 2010..We recommend that MI be further evaluated in OCD by exploring alternative modes of delivery and by focusing on patients less ready for change than the current sample...
Prevalence of hoarding disorder in individuals at potential risk of eviction in New York City: a pilot studyCarolyn I Rodriguez
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
J Nerv Ment Dis 200:91-4. 2012..Future studies are needed to determine whether HD treatment can reduce the risk of eviction and homelessness in NYC...
Pharmacological treatment of obsessive-compulsive disorderHelen Blair Simpson
Anxiety Disorder Clinic, Columbia University, New York, New York 10032, USA
Curr Top Behav Neurosci 2:527-43. 2010..Finally, novel strategies which are based on an increased understanding of the brain mechanisms underlying OCD and which are under investigation will be reviewed...
Are there reliable neuropsychological deficits in obsessive-compulsive disorder?Helen Blair Simpson
New York State Psychiatric Institute, Unit 69, 1051 Riverside Drive, New York, NY, USA
J Psychiatr Res 40:247-57. 2006..Whether there are reliable neuropsychological deficits in OCD that can be easily identified in a clinical sample and that contribute to functional impairment remains unclear and requires further study...
