Shonni Silverberg

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi The diagnosis and management of asymptomatic primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nat Clin Pract Endocrinol Metab 2:494-503. 2006
  2. ncbi Asymptomatic primary hyperparathyroidism
    Shonni J Silverberg
    Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Densitom 16:14-21. 2013
  3. ncbi Aortic valve calcification in mild primary hyperparathyroidism
    Shinichi Iwata
    Department of Medicine, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 97:132-7. 2012
  4. ncbi Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop
    Shonni J Silverberg
    Columbia University College of Physicians and Surgeons, 630 West 168th Street, PH 8W 864, New York, New York 10032, USA
    J Clin Endocrinol Metab 94:351-65. 2009
  5. ncbi Cinacalcet hydrochloride reduces the serum calcium concentration in inoperable parathyroid carcinoma
    S J Silverberg
    College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 92:3803-8. 2007
  6. ncbi Rheumatic manifestations of primary hyperparathyroidism and parathyroid hormone therapy
    Mishaela R Rubin
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th Street, New York, NY 10032, USA
    Curr Rheumatol Rep 4:179-85. 2002
  7. ncbi Asymptomatic primary hyperparathyroidism: a medical perspective
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Surg Clin North Am 84:787-801. 2004
  8. ncbi "Incipient" primary hyperparathyroidism: a "forme fruste" of an old disease
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:5348-52. 2003
  9. ncbi Clinical utility of an immunoradiometric assay for parathyroid hormone (1-84) in primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:4725-30. 2003
  10. ncbi Age as a criterion for surgery in primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Med 113:681-4. 2002

Research Grants

  1. Non-Classical Manifestations of Primary Hyperparathyroidism
    Shonni Silverberg; Fiscal Year: 2007
  2. PRIMARY HYPERPARATHYROIDISM: NON-CLASSICAL MANIFESTATIONS
    Shonni Silverberg; Fiscal Year: 2009
  3. Vitamin D Deficiency in Primary Hyperparathyroidism
    Shonni J Silverberg; Fiscal Year: 2010

Detail Information

Publications38

  1. ncbi The diagnosis and management of asymptomatic primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nat Clin Pract Endocrinol Metab 2:494-503. 2006
    ....
  2. ncbi Asymptomatic primary hyperparathyroidism
    Shonni J Silverberg
    Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Densitom 16:14-21. 2013
    ..In addition, we will summarize available information on treatment indications and options for those with asymptomatic disease...
  3. ncbi Aortic valve calcification in mild primary hyperparathyroidism
    Shinichi Iwata
    Department of Medicine, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 97:132-7. 2012
    ..It is unclear whether cardiovascular disease is present in primary hyperparathyroidism (PHPT)...
  4. ncbi Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop
    Shonni J Silverberg
    Columbia University College of Physicians and Surgeons, 630 West 168th Street, PH 8W 864, New York, New York 10032, USA
    J Clin Endocrinol Metab 94:351-65. 2009
    ..We present the results of a literature review on issues arising from the clinical presentation and natural history of PHPT...
  5. ncbi Cinacalcet hydrochloride reduces the serum calcium concentration in inoperable parathyroid carcinoma
    S J Silverberg
    College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 92:3803-8. 2007
    ....
  6. ncbi Rheumatic manifestations of primary hyperparathyroidism and parathyroid hormone therapy
    Mishaela R Rubin
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th Street, New York, NY 10032, USA
    Curr Rheumatol Rep 4:179-85. 2002
    ..Clinically overt rheumatologic and skeletal effects are mainly of historical interest. Skeletal disease is still detectable by more sensitive techniques. In certain circumstances, PTH may be protective and anabolic for the skeleton...
  7. ncbi Asymptomatic primary hyperparathyroidism: a medical perspective
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Surg Clin North Am 84:787-801. 2004
    ..These guidelines are elucidated, and new options in the medical therapeutics of primary hyperparathyroidism are discussed...
  8. ncbi "Incipient" primary hyperparathyroidism: a "forme fruste" of an old disease
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:5348-52. 2003
    ....
  9. ncbi Clinical utility of an immunoradiometric assay for parathyroid hormone (1-84) in primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:4725-30. 2003
    ..This study also provides evidence that both PTH (1-84) and PTH fragments are produced in parathyroid adenomas and that peripheral metabolism of hormone and fragment does not alter the proportion of bioactive hormone...
  10. ncbi Age as a criterion for surgery in primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Med 113:681-4. 2002
  11. ncbi Clinical practice. Asymptomatic primary hyperparathyroidism
    John P Bilezikian
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York 10032, USA
    N Engl J Med 350:1746-51. 2004
  12. ncbi Oxyphil parathyroid adenoma: a malignant presentation of a benign disease
    Jessica Fleischer
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 89:5948-51. 2004
    ..In patients with PHPT who present with severe or atypical clinical features, oxyphil adenoma should be considered...
  13. ncbi Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century
    John P Bilezikian
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Bone Miner Res 17:N2-11. 2002
  14. ncbi Dynamic and structural properties of the skeleton in hypoparathyroidism
    Mishaela R Rubin
    College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Bone Miner Res 23:2018-24. 2008
    ..032 +/- 0.028 microm(3)/microm(2)/d, p < 0.0001), were profoundly suppressed in the hypoparathyroid subjects. We conclude that hypoparathyroidism is characterized by markedly unusual structural and dynamic properties of bone...
  15. ncbi Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century
    John P Bilezikian
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:5353-61. 2002
  16. ncbi Calcimimetics: therapeutic potential in hyperparathyroidism
    Adi Cohen
    Division of Endocrinology, Columbia Presbyterian Medical Center, 622 West 168th Street, PH 8WEST 864, New York, NY 10032, USA
    Curr Opin Pharmacol 2:734-9. 2002
    ..These calcimimetic agents hold promise as potential treatments for diseases of parathyroid hyperfunction, such as primary and secondary hyperparathyroidism...
  17. ncbi The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 years
    Mishaela R Rubin
    Department of Medicine, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 93:3462-70. 2008
    ..We previously reported that calciotropic indices and bone mineral density (BMD) are stable in untreated patients for up to a decade, whereas after parathyroidectomy, normalization of biochemistries and increases in BMD ensue...
  18. ncbi Asymptomatic primary hyperparathyroidism
    John P Bilezikian
    Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arq Bras Endocrinol Metabol 50:647-56. 2006
    ..In this article, we will review important clinical and diagnostic features of asymptomatic primary hyperparathyroidism as well as considerations for surgical or medical management of the disease...
  19. ncbi Neuropsychological features in primary hyperparathyroidism: a prospective study
    MARCELLA D WALKER
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 94:1951-8. 2009
    ..Data regarding the presence, extent, and reversibility of psychological and cognitive features of primary hyperparathyroidism (PHPT) are conflicting...
  20. ncbi Three dimensional cancellous bone structure in hypoparathyroidism
    Mishaela R Rubin
    Metabolic Bone Diseases Unit, Department of Medicine, College of Physicians and Surgeons, Columbia University New York, NY, USA
    Bone 46:190-5. 2010
    ..The effect of these structural changes on bone strength remains to be determined...
  21. ncbi Normocalcemic primary hyperparathyroidism
    John P Bilezikian
    Departamento de Medicina, Columbia University, NY, NY, USA
    Arq Bras Endocrinol Metabol 54:106-9. 2010
    ..In this article, we describe this new entity, normocalcemic primary hyperparathyroidism, a forme fruste of the disease...
  22. ncbi Human chorionic gonadotropin measurements in parathyroid carcinoma
    Mishaela R Rubin
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Eur J Endocrinol 159:469-74. 2008
    ..We investigated whether hCG can distinguish PtCa cancer from benign disease and add prognostic information...
  23. ncbi Vitamin D deficiency influences histomorphometric features of bone in primary hyperparathyroidism
    Emily M Stein
    College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Bone 48:557-61. 2011
    ..Vitamin D deficiency is common in patients with primary hyperparathyroidism (PHPT). The presence of low levels of vitamin D may affect the skeletal consequences of PHPT...
  24. ncbi An N-terminal molecular form of parathyroid hormone (PTH) distinct from hPTH(1 84) is overproduced in parathyroid carcinoma
    Mishaela R Rubin
    College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Clin Chem 53:1470-6. 2007
    ..We investigated whether N-PTH is also overproduced in parathyroid cancer and whether N-PTH concentration is influenced by calcimimetic therapy...
  25. ncbi Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism
    Mishaela R Rubin
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:1174-8. 2003
    ..Calcium and bone marker changes were therefore similar to those observed with ERT in PHPT. This short-term study suggests that raloxifene may be a useful approach to the treatment of postmenopausal women with mild PHPT...
  26. ncbi Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the third international workshop
    John P Bilezikian
    Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 94:335-9. 2009
    ..CONSENSUS PROCESS: Consensus was achieved by a group meeting. Statements were prepared and reviewed by all authors who represented the Planning Committee and the participating professional societies...
  27. ncbi Non-classical target organs in primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Bone Miner Res 17:N117-25. 2002
    ..With available data suggesting that many asymptomatic patients with PHPT can be safely followed without parathyroidectomy, this information will be of key importance in the management of such individuals...
  28. ncbi Vitamin D deficiency and primary hyperparathyroidism
    Shonni J Silverberg
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Bone Miner Res 22:V100-4. 2007
    ....
  29. ncbi Carotid artery plaque thickness is associated with increased serum calcium levels: the Northern Manhattan study
    Mishaela R Rubin
    Department of Medicine, Columbia University College of Physicians and Surgeons, PH8W 864, 630 W 168th St, New York, NY 10032, USA
    Atherosclerosis 194:426-32. 2007
    ..We investigated the association between serum calcium and carotid plaque thickness, a powerful early predictor of clinical coronary and cerebrovascular events...
  30. ncbi Prevention of bone loss after withdrawal of tamoxifen
    Adi Cohen
    Department of Medicine, Division of Endocrinology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Endocr Pract 14:162-7. 2008
    ..The objective of this study was to assess, in a randomized, double-blind, placebo-controlled trial, whether administration of alendronate (70 mg weekly) would prevent bone loss associated with tamoxifen discontinuation...
  31. ncbi Arterial stiffness in mild primary hyperparathyroidism
    Mishaela R Rubin
    Columbia University, College of Physicians and Surgeons, Department of Medicine, PH8-864, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 90:3326-30. 2005
    ..05). The diagnosis of primary hyperparathyroidism was therefore an independent predictor of increased AIx, an early measure of arterial stiffness, and the increase was associated with evidence of more active parathyroid disease...
  32. ncbi Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan study
    Angela L Carrelli
    Department of Medicine, College of Physicians and Surgeons, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Stroke 42:2240-5. 2011
    ..The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events...
  33. ncbi Bone quality determined by Fourier transform infrared imaging analysis in mild primary hyperparathyroidism
    Ruth Zoehrer
    Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK Social Health Insurance Vienna, Vienna, Austria
    J Clin Endocrinol Metab 93:3484-9. 2008
    ..Hence, there is need to characterize this disorder with particular attention to the skeleton...
  34. ncbi Parathyroidectomy in asymptomatic primary hyperparathyroidism: improves "bones" but not "psychic moans"
    MARCELLA D WALKER
    J Clin Endocrinol Metab 92:1613-5. 2007
  35. ncbi Alendronate in primary hyperparathyroidism: a double-blind, randomized, placebo-controlled trial
    Aliya A Khan
    McMaster University, 331 209 Sheddon Avenue, Oakville, Ontario, Canada L6J 1X8
    J Clin Endocrinol Metab 89:3319-25. 2004
    ..Significant reductions in bone turnover occur with stable serum calcium and PTH levels. Alendronate may be a useful alternative to parathyroidectomy in asymptomatic PHPT among those with low BMD...
  36. ncbi Vascular calcification and osteoporosis--the nature of the nexus
    Mishaela R Rubin
    J Clin Endocrinol Metab 89:4243-5. 2004
  37. ncbi Editorial: HRPT2 in parathyroid cancer: a piece of the puzzle
    Mishaela R Rubin
    J Clin Endocrinol Metab 90:5505-7. 2005
  38. ncbi New observations on bone quality in mild primary hyperparathyroidism as determined by quantitative backscattered electron imaging
    Paul Roschger
    Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 4th Department, Hanusch Hospital, Vienna, Austria
    J Bone Miner Res 22:717-23. 2007
    ..A strong correlation between bone turnover status and degree and heterogeneity of mineralization was found. Further studies are needed before we can draw conclusions about fracture risk in this disorder...

Research Grants8

  1. Non-Classical Manifestations of Primary Hyperparathyroidism
    Shonni Silverberg; Fiscal Year: 2007
    ....
  2. PRIMARY HYPERPARATHYROIDISM: NON-CLASSICAL MANIFESTATIONS
    Shonni Silverberg; Fiscal Year: 2009
    ..abstract_text> ..
  3. Vitamin D Deficiency in Primary Hyperparathyroidism
    Shonni J Silverberg; Fiscal Year: 2010
    ....