Rae Silver

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. doi request reprint Mast cells on the mind: new insights and opportunities
    Rae Silver
    Department of Psychology, Barnard College, 3009 Broadway, New York, NY 10027, USA Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA Electronic address
    Trends Neurosci 36:513-21. 2013
  2. pmc Food anticipation depends on oscillators and memories in both body and brain
    Rae Silver
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Physiol Behav 104:562-71. 2011
  3. doi request reprint Circadian and homeostatic factors in arousal
    Rae Silver
    Department of Psychology, Columbia University, New York, New York 10027, USA
    Ann N Y Acad Sci 1129:263-74. 2008
  4. pmc Neurotech for neuroscience: unifying concepts, organizing principles, and emerging tools
    Rae Silver
    Psychology Department, Barnard College of Columbia University, New York, New York 10027, USA
    J Neurosci 27:11807-19. 2007
  5. pmc Day-length encoding through tonic photic effects in the retinorecipient SCN region
    Lily Yan
    Department of Psychology, Columbia University, New York, NY, USA
    Eur J Neurosci 28:2108-15. 2008
  6. pmc Androgens modulate structure and function of the suprachiasmatic nucleus brain clock
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, New York 10027, USA
    Endocrinology 152:1970-8. 2011
  7. ncbi request reprint DARPP-32 involvement in the photic pathway of the circadian system
    Lily Yan
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 26:9434-8. 2006
  8. pmc Dose-dependent effects of androgens on the circadian timing system and its response to light
    Matthew P Butler
    Columbia University, Department of Psychology, 406 Schermerhorn Hall, 1190 Amsterdam Avenue, New York, New York 10027, USA
    Endocrinology 153:2344-52. 2012
  9. pmc Phenotype matters: identification of light-responsive cells in the mouse suprachiasmatic nucleus
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 24:68-75. 2004
  10. pmc Temporal and spatial expression patterns of canonical clock genes and clock-controlled genes in the suprachiasmatic nucleus
    Toshiyuki Hamada
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Eur J Neurosci 19:1741-8. 2004

Research Grants

  1. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2006
  2. suprachiasmatic nucleus (SCN) networks and efferent signals
    Rae Silver; Fiscal Year: 2007
  3. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2007
  4. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2009
  5. suprachiasmatic nucleus (SCN) networks and efferent signals
    Rae Silver; Fiscal Year: 2009
  6. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2010
  7. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2005
  8. The Immune Response in Mast Cell Deficient Mice
    Rae Silver; Fiscal Year: 2005
  9. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 1999
  10. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 1999

Collaborators

Detail Information

Publications64

  1. doi request reprint Mast cells on the mind: new insights and opportunities
    Rae Silver
    Department of Psychology, Barnard College, 3009 Broadway, New York, NY 10027, USA Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA Electronic address
    Trends Neurosci 36:513-21. 2013
    ..New experimental tools enabling isolation of brain MCs, manipulation of MCs or their products, and measurement of MC products in very small brain volumes present unprecedented opportunities for examining these enigmatic cells. ..
  2. pmc Food anticipation depends on oscillators and memories in both body and brain
    Rae Silver
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Physiol Behav 104:562-71. 2011
    ..Cues temporally near and far from actual energy content can then be used to optimize responses to temporally predictable and unpredictable cues in the environment...
  3. doi request reprint Circadian and homeostatic factors in arousal
    Rae Silver
    Department of Psychology, Columbia University, New York, New York 10027, USA
    Ann N Y Acad Sci 1129:263-74. 2008
    ....
  4. pmc Neurotech for neuroscience: unifying concepts, organizing principles, and emerging tools
    Rae Silver
    Psychology Department, Barnard College of Columbia University, New York, New York 10027, USA
    J Neurosci 27:11807-19. 2007
    ..Funding agencies, including the National Science Foundation, explore the potential of these changing frontiers of research for developing research policies and long-term planning...
  5. pmc Day-length encoding through tonic photic effects in the retinorecipient SCN region
    Lily Yan
    Department of Psychology, Columbia University, New York, NY, USA
    Eur J Neurosci 28:2108-15. 2008
    ..The results suggest that the seasonal encoding of day-length by the SCN entails reorganization of its constituent oscillators by a subgroup of neurons in the SCN core that respond to tonic photic cues...
  6. pmc Androgens modulate structure and function of the suprachiasmatic nucleus brain clock
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, New York 10027, USA
    Endocrinology 152:1970-8. 2011
    ..Together, the results reveal a role for androgens in regulating circuitry in the mouse SCN, with functional consequences for clock gene expression and behavioral responses to photic phase resetting stimuli...
  7. ncbi request reprint DARPP-32 involvement in the photic pathway of the circadian system
    Lily Yan
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 26:9434-8. 2006
    ..DARPP-32 was expressed in the retina but not in the IGL or the SCN. The results indicate that DARPP-32 is involved in the retinal pathway transmitting photic information that resets the circadian clock...
  8. pmc Dose-dependent effects of androgens on the circadian timing system and its response to light
    Matthew P Butler
    Columbia University, Department of Psychology, 406 Schermerhorn Hall, 1190 Amsterdam Avenue, New York, New York 10027, USA
    Endocrinology 153:2344-52. 2012
    ..Finally, the effects of androgens on period are a result of hormonal modulation of the SCN's response to photic input rather than to a change in the inherent period of oscillators in the absence of light...
  9. pmc Phenotype matters: identification of light-responsive cells in the mouse suprachiasmatic nucleus
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 24:68-75. 2004
    ..Furthermore, the findings suggest that gastrin-releasing peptide is a potential mediator of intercellular communication between light-induced and oscillator cells within the SCN...
  10. pmc Temporal and spatial expression patterns of canonical clock genes and clock-controlled genes in the suprachiasmatic nucleus
    Toshiyuki Hamada
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Eur J Neurosci 19:1741-8. 2004
    ..The results suggest that not only is the SCN organized into light-responsive and rhythmic regions but also that the rhythmic region of the SCN itself has an ordered arrangement of SCN oscillator cells...
  11. pmc Cellular localization and function of DARPP-32 in the rodent retina
    Paul Witkovsky
    Department of Ophthalmology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Eur J Neurosci 25:3233-42. 2007
    ..We also tested for a possible circadian rhythm of Thr 34- and Thr 75-DARPP-32 and Ser 845-GluR1 expression. No significant circadian rhythm of either DARPP-32 or GluR1 phosphorylation was found...
  12. pmc A short half-life GFP mouse model for analysis of suprachiasmatic nucleus organization
    Joseph LeSauter
    Department of Psychology, Barnard College, 3009 Broadway, New York, NY 10027, USA
    Brain Res 964:279-87. 2003
    ..A surprising finding is that, at their peak expression time GFP, Per1 mRNA, PER1 and PER2 proteins are absent or not detectable in a subpopulation of SCN cells located in the core region of the nucleus...
  13. pmc Cellular location and circadian rhythm of expression of the biological clock gene Period 1 in the mouse retina
    Paul Witkovsky
    Department of Ophthalmology, New York University School of Medicine, New York, New York 10016, USA
    J Neurosci 23:7670-6. 2003
    ..Our results are the first to demonstrate a circadian rhythm of a biological clock component in identified neurons of a mammalian retina...
  14. pmc Stomach ghrelin-secreting cells as food-entrainable circadian clocks
    Joseph LeSauter
    Department of Psychology, Barnard College, 3009 Broadway, New York, NY 10027, USA
    Proc Natl Acad Sci U S A 106:13582-7. 2009
    ..It is likely that other FEOs also produce humoral signals that modulate FAA...
  15. pmc Two antiphase oscillations occur in each suprachiasmatic nucleus of behaviorally split hamsters
    Lily Yan
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 25:9017-26. 2005
    ..These results suggest a neural basis for internal coincidence of SCN oscillators, and a novel mechanism of plasticity in SCN neural networks and outputs...
  16. pmc Brain mast cell relationship to neurovasculature during development
    Mona Khalil
    Department of Biochemistry and Molecular Biophysics, Columbia University, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Brain Res 1171:18-29. 2007
    ..The biochemical and molecular signals that induce mast cell homing in the CNS is an area of active investigation...
  17. pmc Resetting the brain clock: time course and localization of mPER1 and mPER2 protein expression in suprachiasmatic nuclei during phase shifts
    Lily Yan
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Eur J Neurosci 19:1105-9. 2004
    ....
  18. pmc A role for androgens in regulating circadian behavior and the suprachiasmatic nucleus
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Endocrinology 148:5487-95. 2007
    ..As such, the SCN regulates circadian rhythms in gonadal hormone secretion, and in turn, androgens act on their receptors within the SCN to alter circadian function...
  19. pmc Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice
    Eiko Iwahana
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Horm Behav 53:422-30. 2008
    ..The results indicate that androgenic hormones regulate circadian responses, and suggest an SCN site of action...
  20. pmc Targeted microlesions reveal novel organization of the hamster suprachiasmatic nucleus
    Lance J Kriegsfeld
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 24:2449-57. 2004
    ..Together, these findings suggest a novel fundamental property of SCN organization, with a subset of cells being critical for the maintenance of SCN function manifest in circadian rhythms in physiology and behavior...
  21. pmc Twelve-hour days in the brain and behavior of split hamsters
    Matthew P Butler
    Department of Psychology, Columbia University, New York, NY, USA
    Eur J Neurosci 36:2556-66. 2012
    ..Finally, the transduction of 24-h SCN rhythms to 12-h extra-SCN rhythms indicates that each SCN signals both ipsilateral and contralateral targets...
  22. pmc Neurogenesis and ontogeny of specific cell phenotypes within the hamster suprachiasmatic nucleus
    Michael C Antle
    Department of Psychology, Columbia University, NY 10027, USA
    Brain Res Dev Brain Res 157:8-18. 2005
    ..These comparisons suggest the possibility that these coincident appearances may be causally related, with the direction of causation to be determined...
  23. pmc Diurnal regulation of the gastrin-releasing peptide receptor in the mouse circadian clock
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Eur J Neurosci 23:1047-53. 2006
    ..Together, the present findings reveal that changes in GRPr are light driven and not endogenously organized. Diurnal variation in GRPr activity probably underlies intra-SCN signaling important for entrainment and phase shifting...
  24. pmc Basis of robustness and resilience in the suprachiasmatic nucleus: individual neurons form nodes in circuits that cycle daily
    Matthew P Butler
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Biol Rhythms 24:340-52. 2009
    ..Resilience is expressed in the ability of SCN cells to oscillate and to sustain activity-related rhythms at the behavioral level. Importantly, other aspects of pacemaker function remain to be examined...
  25. pmc Calbindin influences response to photic input in suprachiasmatic nucleus
    Toshiyuki Hamada
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 23:8820-6. 2003
    ..These results suggest a cellular basis for temporal gating of photic input to the circadian clock...
  26. pmc Brain mast cells link the immune system to anxiety-like behavior
    Katherine M Nautiyal
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Proc Natl Acad Sci U S A 105:18053-7. 2008
    ..Taken together, the data implicate brain mast cells in the modulation of anxiety-like behavior and provide evidence for the behavioral importance of neuroimmune links...
  27. pmc Targeted mutation of the calbindin D 28k gene selectively alters nonvisual photosensitivity
    Matthew P Butler
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Eur J Neurosci 33:2299-307. 2011
    ....
  28. pmc Circadian trafficking of calbindin-ir in fibers of SCN neurons
    Joseph LeSauter
    Department of Psychology, Barnard College, New York, NY, USA
    J Biol Rhythms 24:488-96. 2009
    ..There was no detectable variation in appositions from any peptidergic fiber type onto CalB cells. The present findings suggest that CalB cells relay photic information to VP oscillator cells of the SCN shell in a temporally gated manner...
  29. pmc Phase shifts and Per gene expression in mouse suprachiasmatic nucleus
    Lily Yan
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Neuroreport 14:1247-51. 2003
    ..No difference was found between lines in light-induced mPer1 expression. The results suggest a more important role for mPer2 than for mPer1 gene expression in behavioral phase delays...
  30. pmc Mast cells are necessary for the hypothermic response to LPS-induced sepsis
    Katherine M Nautiyal
    Dept of Psychology, Columbia Univ, New York, NY 10027, USA
    Am J Physiol Regul Integr Comp Physiol 296:R595-602. 2009
    ..These results indicate that mast cells play a role in the regulation of thermoregulatory responses and survival following sepsis induction and suggest a brain site of action...
  31. pmc Blunted refeeding response and increased locomotor activity in mice lacking FoxO1 in synapsin-Cre-expressing neurons
    Hongxia Ren
    Berrie Diabetes Center, New York, New York
    Diabetes 62:3373-83. 2013
    ....
  32. pmc Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus
    Joseph LeSauter
    Department of Psychology, Barnard College of Columbia University, New York, New York, USA
    PLoS ONE 7:e35938. 2012
    ..Our results identify antibodies against PER1, PER2, BMAL1 and CLOCK that are useful for assessing circadian clock proteins in the SCN by immunocytochemistry...
  33. pmc Light exposure induces short- and long-term changes in the excitability of retinorecipient neurons in suprachiasmatic nucleus
    Joseph LeSauter
    Department of Psychology, Barnard College, New York, NY, USA
    J Neurophysiol 106:576-88. 2011
    ....
  34. pmc Signaling within the master clock of the brain: localized activation of mitogen-activated protein kinase by gastrin-releasing peptide
    Michael C Antle
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Neurosci 25:2447-54. 2005
    ..These findings represent a first step in deconstructing the SCN network constituting the brain clock...
  35. pmc Serotonin of mast cell origin contributes to hippocampal function
    Katherine M Nautiyal
    Psychology Department, Columbia University, 406 Schermerhorn Hall, 1190 Amsterdam Ave, New York, NY 10027, USA
    Eur J Neurosci 36:2347-59. 2012
    ..We conclude that mast cells contribute to behavioral and physiological functions of the hippocampus and note that they play a physiological role in neuroimmune interactions, even in the absence of inflammatory responses...
  36. pmc Divergent photic thresholds in the non-image-forming visual system: entrainment, masking and pupillary light reflex
    Matthew P Butler
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Proc Biol Sci 278:745-50. 2011
    ..Photosensitivity to one response, therefore, cannot be generalized to other non-image-forming functions. These results also impact practical problems in selecting appropriate lighting in laboratory animal husbandry...
  37. pmc Expression of the circadian clock gene Period 1 in neuroendocrine cells: an investigation using mice with a Per1::GFP transgene
    Lance J Kriegsfeld
    Department of Psychology, Columbia University New York, 1190 Amsterdam Avenue, New York, 10027, USA
    Eur J Neurosci 17:212-20. 2003
    ..These findings also indicate that the endocrine system represents an opportunity to study the interactions between central (SCN and neuroendocrine cells) and peripheral circadian (endocrine gland) oscillators...
  38. pmc Two forces for arousal: Pitting hunger versus circadian influences and identifying neurons responsible for changes in behavioral arousal
    Ana C Ribeiro
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:20078-83. 2007
    ..01). Because the activation of VMH neurons coincides with the earliest signs of behavioral arousal preceding a change in meal time, we infer that VMH activation is involved in the increased arousal in anticipation of food...
  39. pmc Organization of suprachiasmatic nucleus projections in Syrian hamsters (Mesocricetus auratus): an anterograde and retrograde analysis
    Lance J Kriegsfeld
    Department of Psychology, Columbia University, New York, New York 10027, USA
    J Comp Neurol 468:361-79. 2004
    ....
  40. pmc Food-entrained circadian rhythms are sustained in arrhythmic Clk/Clk mutant mice
    SiNae Pitts
    Dept of Psychology, Columbia University, 1190 Amsterdam Ave MC 5501, New York, NY 10027, USA
    Am J Physiol Regul Integr Comp Physiol 285:R57-67. 2003
    ..This is the first demonstration that the Clock gene is not necessary for the expression of a circadian, food-entrained behavior and suggests that the FEO is mediated by a molecular mechanism distinct from that of the SCN...
  41. pmc Photoperiod and reproductive condition are associated with changes in RFamide-related peptide (RFRP) expression in Syrian hamsters (Mesocricetus auratus)
    Alex O Mason
    Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
    J Biol Rhythms 25:176-85. 2010
    ....
  42. pmc Minireview: The neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals
    Ilia N Karatsoreos
    Department of Psychology, Columbia University, 406 Schermerhorn Hall, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Endocrinology 148:5640-7. 2007
    ..Thus, this system has multiple levels of regulation; the SCN regulates circadian rhythms in gonadal hormone secretion, and hormones feed back to influence SCN functions...
  43. pmc Mast cells in the rat brain synthesize gonadotropin-releasing hormone
    Mona H Khalil
    Department of Biochemistry and Molecular Biophysics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurobiol 56:113-24. 2003
    ....
  44. pmc Is cognitive functioning impaired in methamphetamine users? A critical review
    Carl L Hart
    Department of Psychology, Columbia University, New York, NY 10032, USA
    Neuropsychopharmacology 37:586-608. 2012
    ..The implications of this situation are multiple, with consequences for scientific research, substance-abuse treatment, and public policy...
  45. pmc Blood-borne donor mast cell precursors migrate to mast cell-rich brain regions in the adult mouse
    Katherine M Nautiyal
    Department of Psychology, Columbia University, New York, NY 10027, United States
    J Neuroimmunol 240:142-6. 2011
    ..In contrast, in Kit(W-sh/W-sh) mice, transfusion results in mast cells in the pinna of the ear, but not the brain...
  46. pmc Brain mast cells are influenced by chemosensory cues associated with estrus induction in female prairie voles (Microtus ochrogaster)
    Lance J Kriegsfeld
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Horm Behav 44:377-84. 2003
    ....
  47. pmc Differential induction and localization of mPer1 and mPer2 during advancing and delaying phase shifts
    Lily Yan
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Eur J Neurosci 16:1531-40. 2002
    ..The results indicate that the time course and the localization of light-induced Per gene expression in SCN reveals important aspects of intra-SCN communication...
  48. pmc Gates and oscillators: a network model of the brain clock
    Michael C Antle
    Department of Psychology, Columbia University, New York, NY 10027, USA
    J Biol Rhythms 18:339-50. 2003
    ..The model explains how individual SCN cells oscillate independently and yet work together to produce a coherent rhythm...
  49. ncbi request reprint Gene-hormone-environment interactions in the regulation of aggressive responses: elegant analysis of complex behavior
    Donald Pfaff
    Laboratory of Neurobiology and Behavior, Rockefeller University, New York, NY 10021, USA
    Sci STKE 2007:pe55. 2007
    ..The effects of estrogens on aggression are modulated by day length and involve both genomic and nongenomic routes of hormone action...
  50. ncbi request reprint The skinny on body weight regulation: the role of retinoid signaling in photoperiod-mediated weight loss
    Lance J Kriegsfeld
    Department of Psychology, Columbia University, New York, New York 10027, USA
    Endocrinology 145:11-2. 2004
  51. ncbi request reprint Circadian rhythms have broad implications for understanding brain and behavior
    Rae Silver
    Department of Psychology, Barnard College, Columbia University, New York, NY, USA Department of Psychology, Columbia University, Mail Code 5501, 1190 Amsterdam Avenue, New York, NY, 10027, USA Department of Pathology and Cell Biology, Columbia University Health Sciences, New York, NY, USA
    Eur J Neurosci 39:1866-80. 2014
    ....
  52. ncbi request reprint GnRH, brain mast cells and behavior
    Ann Judith Silverman
    Department of Anatomy and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Prog Brain Res 141:315-25. 2002
  53. doi request reprint Time of day influences the voluntary intake and behavioral response to methamphetamine and food reward
    Diana R Keith
    Department of Psychology, Columbia University, New York, NY, USA
    Pharmacol Biochem Behav 110:117-26. 2013
    ..The results indicate that time of day is an important variable mediating the voluntary intake and behavioral effects of reinforcers. ..
  54. pmc Residual effects of intranasal methamphetamine on sleep, mood, and performance
    Audrey Y Perez
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 94:258-62. 2008
    ..Methamphetamine did not produce any negative residual effects on early next-day performance. Future studies should assess methamphetamine-related residual effects following repeated doses administered over consecutive days...
  55. pmc The role of Period1 in non-photic resetting of the hamster circadian pacemaker in the suprachiasmatic nucleus
    Toshiyuki Hamada
    Age Dimension Research Center, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6th site 1 1 1, Higashi, Tsukuba, Ibaraki, 305 8562, Japan
    Neurosci Lett 362:87-90. 2004
    ..These results indicate that the decrease in expression of Per1 is a cause rather than a consequence of non-photic phase shifts...
  56. ncbi request reprint The eye is necessary for a circadian rhythm in the suprachiasmatic nucleus
    Han S Lee
    Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Nat Neurosci 6:111-2. 2003
  57. pmc Phase resetting light pulses induce Per1 and persistent spike activity in a subpopulation of biological clock neurons
    Sandra J Kuhlman
    Department of Physiology, University of Kentucky, Lexington, Kentucky 40536 0084, USA
    J Neurosci 23:1441-50. 2003
    ....
  58. ncbi request reprint Suckling and genital stroking induces Fos expression in hypothalamic oxytocinergic neurons of rabbit pups
    Mario Caba
    Lab Biologi a de la Reproducción, IIB, Universidad Veracruzana, A P 114, Xalapa, Ver 91, 000, Mexico
    Brain Res Dev Brain Res 143:119-28. 2003
    ..In conclusion, our results show that the oxytocinergic system of the SON and PVN is differentially activated by suckling of milk and anogenital stroking, and that the vagal-hypothalamic axis is mature in 7-day-old rabbits...
  59. pmc Nature's food anticipatory experiment: entrainment of locomotor behavior, suprachiasmatic and dorsomedial hypothalamic nuclei by suckling in rabbit pups
    Mario Caba
    Lab Biol of Reproduction, IIB, Universidad Veracruzana, A P 114, Xalapa 91000, Ver Mexico
    Eur J Neurosci 27:432-43. 2008
    ..The results indicate that rabbit pups show food anticipatory activity, and that timing of nursing differentially affects PER1 expression in the SCN and DMH...
  60. pmc AII amacrine neurons of the rat retina show diurnal and circadian rhythms of parvalbumin immunoreactivity
    Robert Gabriel
    Department of General Zoology and Neurobiology, University of Pecs, 7601 Pécs, u 6, Ifjúság, Hungary
    Cell Tissue Res 315:181-6. 2004
    ..We conclude that PA-IR in the rat retina shows an underlying circadian rhythm that is enhanced by cyclic light. The regulation may involve translocation of the protein between cell compartments and/or new protein synthesis...
  61. pmc Gates and oscillators II: zeitgebers and the network model of the brain clock
    Michael C Antle
    Department of Psychology, University of Calgary, Calgary, AB, Canada
    J Biol Rhythms 22:14-25. 2007
    ....
  62. pmc The regulation of neuroendocrine function: Timing is everything
    Lance J Kriegsfeld
    Department of Psychology and Helen Wills Neuroscience Institute, 3210 Tolman Hall, 1650, University of California, Berkeley, CA 94720 1650, USA
    Horm Behav 49:557-74. 2006
    ....
  63. ncbi request reprint Orchestrating time: arrangements of the brain circadian clock
    Michael C Antle
    Department of Psychology, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada
    Trends Neurosci 28:145-51. 2005
    ..The coordinated interaction of these functionally distinct cells is integral to the coherent functioning of the brain clock...
  64. pmc Targeted mutation of the calbindin D28K gene disrupts circadian rhythmicity and entrainment
    Lance J Kriegsfeld
    Department of Psychology and Helen Wills Neuroscience Institute, 3210 Tolman Hall, University of California, Berkeley, CA 94720, USA
    Eur J Neurosci 27:2907-21. 2008
    ..Together, the developmental pattern of CalB expression in mouse SCN, the presence of CalB in photoresponsive ganglion cells and the abnormalities seen in CalB-/- mice suggest an important role for CalB in mouse circadian function...

Research Grants20

  1. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2006
    ..The work also contributes to a better understanding of circadian changes associated with puberty, andropause, sleep regulation and some aspects of sex differences. ..
  2. suprachiasmatic nucleus (SCN) networks and efferent signals
    Rae Silver; Fiscal Year: 2007
    ..The hypothesis is that we will be able to delineate the relationship between activity of specific intra-SCN networks and brain target sites thereby addressing the long-sought explanation for SCN heterogeneity. ..
  3. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2007
    ..The work also contributes to a better understanding of circadian changes associated with puberty, andropause, sleep regulation and some aspects of sex differences. ..
  4. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2009
    ..The work also contributes to a better understanding of circadian changes associated with puberty, andropause, sleep regulation and some aspects of sex differences. ..
  5. suprachiasmatic nucleus (SCN) networks and efferent signals
    Rae Silver; Fiscal Year: 2009
    ..The hypothesis is that we will be able to delineate the relationship between activity of specific intra-SCN networks and brain target sites thereby addressing the long-sought explanation for SCN heterogeneity. ..
  6. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2010
    ..The work also contributes to a better understanding of circadian changes associated with puberty, andropause, sleep regulation and some aspects of sex differences. ..
  7. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2005
    ..abstract_text> ..
  8. The Immune Response in Mast Cell Deficient Mice
    Rae Silver; Fiscal Year: 2005
    ..This application will determine whether mast cells play a role in mounting an immune response in the brain. ..
  9. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 1999
    ..which in turn are driven by SCN pacemakers (or, are all cells pacemakers)? Do different subsets of SCN cells regulate different rhythms (reach different targets)? Or, is there a core of cells that regulates all circadian rhythms? ..
  10. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 1999
    ..which in turn are driven by SCN pacemakers (or, are all cells pacemakers)? Do different subsets of SCN cells regulate different rhythms (reach different targets)? Or, is there a core of cells that regulates all circadian rhythms? ..
  11. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2000
    ..which in turn are driven by SCN pacemakers (or, are all cells pacemakers)? Do different subsets of SCN cells regulate different rhythms (reach different targets)? Or, is there a core of cells that regulates all circadian rhythms? ..
  12. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2001
    ..which in turn are driven by SCN pacemakers (or, are all cells pacemakers)? Do different subsets of SCN cells regulate different rhythms (reach different targets)? Or, is there a core of cells that regulates all circadian rhythms? ..
  13. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2002
    ..abstract_text> ..
  14. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2003
    ..abstract_text> ..
  15. Society for Research on Biological Rhythms Meeting
    Rae Silver; Fiscal Year: 2003
    ..A similar request is made for the 9th meeting, to be held in 2004. ..
  16. PHYSIOLOGICAL DISSECTION OF THE SCN
    Rae Silver; Fiscal Year: 2004
    ..abstract_text> ..
  17. suprachiasmatic nucleus (SCN) networks and efferent signals
    Rae Silver; Fiscal Year: 2010
    ..The hypothesis is that we will be able to delineate the relationship between activity of specific intra-SCN networks and brain target sites thereby addressing the long-sought explanation for SCN heterogeneity. ..