Etienne Sibille

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Gene expression profiling of depression and suicide in human prefrontal cortex
    Etienne Sibille
    Department of Psychiatry, Columbia University, New York, NY, USA
    Neuropsychopharmacology 29:351-61. 2004
  2. ncbi request reprint Molecular aging in human prefrontal cortex is selective and continuous throughout adult life
    Loubna Erraji-Benchekroun
    Department of Psychiatry, Columbia University, New York, New York, USA
    Biol Psychiatry 57:549-58. 2005
  3. pmc A molecular signature of depression in the amygdala
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, BST W1643, Pittsburgh, PA 15213, USA
    Am J Psychiatry 166:1011-24. 2009
  4. pmc GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, PA, USA
    Int J Neuropsychopharmacol 14:721-34. 2011
  5. pmc Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry
    Jennifer Joeyen-Waldorf
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15219, USA
    Biol Psychiatry 71:627-32. 2012
  6. pmc Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    J Neurosci Methods 167:198-206. 2008
  7. pmc Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation
    Inna Gaisler-Salomon
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Hippocampus 22:1027-39. 2012
  8. pmc Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction
    Hanga C Galfalvy
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    BMC Bioinformatics 4:37. 2003
  9. ncbi request reprint Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide
    Helene Bach-Mizrachi
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Neuropsychopharmacology 31:814-24. 2006
  10. pmc Sleep-dependent gene expression in the hippocampus and prefrontal cortex following long-term potentiation
    Rodrigo N Romcy-Pereira
    The Rockefeller University, New York, NY, United States
    Physiol Behav 98:44-52. 2009

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Gene expression profiling of depression and suicide in human prefrontal cortex
    Etienne Sibille
    Department of Psychiatry, Columbia University, New York, NY, USA
    Neuropsychopharmacology 29:351-61. 2004
    ....
  2. ncbi request reprint Molecular aging in human prefrontal cortex is selective and continuous throughout adult life
    Loubna Erraji-Benchekroun
    Department of Psychiatry, Columbia University, New York, New York, USA
    Biol Psychiatry 57:549-58. 2005
    ..Aging leads to morphologic and functional changes in the brain and is associated with increased risk for psychiatric and neurological disorders...
  3. pmc A molecular signature of depression in the amygdala
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, BST W1643, Pittsburgh, PA 15213, USA
    Am J Psychiatry 166:1011-24. 2009
    ....
  4. pmc GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, PA, USA
    Int J Neuropsychopharmacol 14:721-34. 2011
    ..Results were not explained by other clinical, demographic or technical parameters. In summary, MDD was characterized by low DLPFC SST, whereas decreased PV mRNA appears to distinguish BPD from MDD...
  5. pmc Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry
    Jennifer Joeyen-Waldorf
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15219, USA
    Biol Psychiatry 71:627-32. 2012
    ....
  6. pmc Large-scale estimates of cellular origins of mRNAs: enhancing the yield of transcriptome analyses
    Etienne Sibille
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    J Neurosci Methods 167:198-206. 2008
    ..As this approach can be applied post hoc, we provide tables of ratios for analysis of existing mouse and human brain datasets...
  7. pmc Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation
    Inna Gaisler-Salomon
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Hippocampus 22:1027-39. 2012
    ..The maturity-onset reduction in NR1 gene expression and in contextual learning supports the premise that glutaminase inhibition in adulthood should prove therapeutic in schizophrenia...
  8. pmc Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction
    Hanga C Galfalvy
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    BMC Bioinformatics 4:37. 2003
    ..We introduce the idea of using sex-chromosome genes as an alternative to spiked-in control genes or simulations for assessment of microarray data and analysis methods...
  9. ncbi request reprint Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide
    Helene Bach-Mizrachi
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Neuropsychopharmacology 31:814-24. 2006
    ..Higher TPH2 mRNA expression may explain more TPH protein observed in depressed suicides and reflect a homeostatic response to deficient brain serotonergic transmission...
  10. pmc Sleep-dependent gene expression in the hippocampus and prefrontal cortex following long-term potentiation
    Rodrigo N Romcy-Pereira
    The Rockefeller University, New York, NY, United States
    Physiol Behav 98:44-52. 2009
    ....
  11. pmc The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice
    Jennifer Joeyen-Waldorf
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Brain Res 1286:84-93. 2009
    ..This sex-by-SERT double dissociation provides a framework to investigate molecular substrates of emotionality regulation in concert with serotonin function and may contribute to the sexually dimorphic features of mood disorders...
  12. pmc Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder
    Adam Tripp
    Department of Psychiatry, University of Pittsburgh, USA
    Am J Psychiatry 169:1194-202. 2012
    ....
  13. pmc Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex
    Jean Philippe Guilloux
    Department of Psychiatry, 3811 O Hara Street, BST W1643, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Neurosci Methods 197:21-31. 2011
    ....
  14. ncbi request reprint Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex
    Paul Pavlidis
    Department of Biomedical Informatics and Columbia Genome Center, Columbia University, New York, New York 10032, USA
    Neurochem Res 29:1213-22. 2004
    ....
  15. pmc A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism
    Li Chun Lin
    Translational Neuroscience Program, Department of Psychiatry, and Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Mol Brain 4:18. 2011
    ..We hypothesized that sex differences in molecular structure may contribute to differential mood regulation and disease vulnerability...
  16. pmc Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders
    Etienne Sibille
    Department of Psychiatry, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15219, USA
    Dialogues Clin Neurosci 15:53-65. 2013
    ....
  17. pmc Brain molecular aging, promotion of neurological disease and modulation by sirtuin 5 longevity gene polymorphism
    Christin Glorioso
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neurobiol Dis 41:279-90. 2011
    ..Confirming this pathway and its regulation by common genetic variants would provide new strategies for predicting, delaying, and treating neurological diseases...
  18. pmc Reduced somatostatin in subgenual anterior cingulate cortex in major depression
    Adam Tripp
    Department of Psychiatry, University of Pittsburgh, PA 15312, USA
    Neurobiol Dis 42:116-24. 2011
    ..Specifically, alterations in SST signaling and/or SST-bearing GABA neurons may represent a critical pathophysiological entity that contributes to sgACC dysfunction and that matches to the high female vulnerability to develop MDD...
  19. pmc Between destiny and disease: genetics and molecular pathways of human central nervous system aging
    Christin Glorioso
    Department of Psychiatry, Center for Neuroscience, Translational Neuroscience Program, University of Pittsburgh, Pittsburgh, PA 15312, USA
    Prog Neurobiol 93:165-81. 2011
    ..Finally, we discuss the implications of this model for understanding basic mechanisms of brain aging and for the future investigation of therapeutic approaches...
  20. pmc Anticipated brain molecular aging in major depression
    Gaelle Douillard-Guilloux
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15219, USA
    Am J Geriatr Psychiatry 21:450-60. 2013
    ..Here, we characterize the global interaction of MDD-related gene changes with age, starting from our previous report of downregulated brain-derived neurotrophic factor (BDNF) and BDNF-dependent genes in the amygdala of women with MDD...
  21. pmc Neonatal testosterone partially organizes sex differences in stress-induced emotionality in mice
    Marianne L Seney
    Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA 15219, USA
    Neurobiol Dis 46:486-96. 2012
    ....
  22. pmc The RNA binding domain of Jerky consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs
    Wencheng Liu
    Department of Pharmacology, Weill Medical College of Cornell University Graduate Program in Neuroscience, Weill Graduate School of Medical Sciences of Cornell University, New York, New York 10021, USA
    Mol Cell Biol 23:4083-93. 2003
    ..These data suggest that epileptogenesis in Jerky-deficient mice most likely involves pathways associated with ribosome biogenesis and neuronal survival and/or apoptosis...
  23. pmc Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells
    Leonardo D'Aiuto
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    PLoS ONE 7:e49700. 2012
    ....
  24. pmc MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis
    Dongwan D Kang
    Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Nucleic Acids Res 40:e15. 2012
    ..The application and simulation results concluded a systematic quality assessment framework for genomic meta-analysis...
  25. pmc Differentially expressed genes in major depression reside on the periphery of resilient gene coexpression networks
    Chris Gaiteri
    Department of Psychiatry, Center for Neuroscience, University of Pittsburgh Pittsburgh, PA, USA
    Front Neurosci 5:95. 2011
    ....
  26. ncbi request reprint Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice
    Noelia V Weisstaub
    Department of Biology, Columbia University and the New York State Psychiatric Institute, New York, NY 10032, USA
    Science 313:536-40. 2006
    ..These findings indicate a specific role for cortical 5HT2AR function in the modulation of conflict anxiety, consistent with models of cortical, "top-down" influences on risk assessment...
  27. ncbi request reprint SERT-ainly involved in depression, but when?
    Etienne Sibille
    Am J Psychiatry 163:8-11. 2006