Kausik Si

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint A neuronal isoform of the aplysia CPEB has prion-like properties
    Kausik Si
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, USA
    Cell 115:879-91. 2003
  2. ncbi request reprint A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia
    Kausik Si
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, USA
    Cell 115:893-904. 2003
  3. pmc Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia
    Maria Concetta Miniaci
    Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive New York, NY 10032, USA
    Neuron 59:1024-36. 2008
  4. pmc Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse
    Maurizio Giustetto
    Center for Neurobiology and Behavior, College of Physicians and Surgeons, New York State Psychiatric Institute, and Howard Hughes Medical Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:13680-5. 2003
  5. pmc Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus
    Martin Theis
    Howard Hughes Medical Institute and Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:9602-7. 2003
  6. ncbi request reprint The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth
    Craig H Bailey
    Center for Neurobiology and Behavior, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 44:49-57. 2004
  7. ncbi request reprint RISC-y Memories
    Erica White-Grindley
    The Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Cell 124:23-6. 2006
  8. pmc Phosphorylation of mammalian eukaryotic translation initiation factor 6 and its Saccharomyces cerevisiae homologue Tif6p: evidence that phosphorylation of Tif6p regulates its nucleocytoplasmic distribution and is required for yeast cell growth
    Uttiya Basu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Mol Cell Biol 23:6187-99. 2003

Collaborators

Detail Information

Publications8

  1. ncbi request reprint A neuronal isoform of the aplysia CPEB has prion-like properties
    Kausik Si
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, USA
    Cell 115:879-91. 2003
    ..We hypothesize that conversion of CPEB to a prion-like state in stimulated synapses helps to maintain long-term synaptic changes associated with memory storage...
  2. ncbi request reprint A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia
    Kausik Si
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, USA
    Cell 115:893-904. 2003
    ..We suggest that Aplysia CPEB is one of the stabilizing components of the synaptic mark...
  3. pmc Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia
    Maria Concetta Miniaci
    Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive New York, NY 10032, USA
    Neuron 59:1024-36. 2008
    ....
  4. pmc Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse
    Maurizio Giustetto
    Center for Neurobiology and Behavior, College of Physicians and Surgeons, New York State Psychiatric Institute, and Howard Hughes Medical Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:13680-5. 2003
    ..The transport of eEF1A protein and its mRNA to nerve terminals suggests that the translation factor plays a role in the local protein synthesis that is essential for maintaining newly formed synapses...
  5. pmc Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus
    Martin Theis
    Howard Hughes Medical Institute and Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:9602-7. 2003
    ..Coexpression of mCPEB-1 and the B region-containing splice isoforms suggests that a variety of different signaling pathways can recruit CPEB activity in hippocampal neurons...
  6. ncbi request reprint The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth
    Craig H Bailey
    Center for Neurobiology and Behavior, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 44:49-57. 2004
    ....
  7. ncbi request reprint RISC-y Memories
    Erica White-Grindley
    The Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Cell 124:23-6. 2006
    ..2006) observe persistent local protein synthesis in the antennal lobe synapses of the fruit fly following olfactory-avoidance learning. This protein synthesis is regulated by the RNA-induced silencing complex (RISC)...
  8. pmc Phosphorylation of mammalian eukaryotic translation initiation factor 6 and its Saccharomyces cerevisiae homologue Tif6p: evidence that phosphorylation of Tif6p regulates its nucleocytoplasmic distribution and is required for yeast cell growth
    Uttiya Basu
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA
    Mol Cell Biol 23:6187-99. 2003
    ..These results suggest that phosphorylatable Ser-174 and Ser-175 play a critical role in the nuclear export of Tif6p...