Jing Shen

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Genetic variation in telomere maintenance genes, telomere length and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e44308. 2012
  2. pmc Dysregulation of circulating microRNAs and prediction of aggressive prostate cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University Medical Center, New York, New York, USA
    Prostate 72:1469-77. 2012
  3. pmc Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 650 West 168th Street, Black Building 1608, New York, NY 10032, USA
    Breast Cancer Res Treat 134:393-400. 2012
  4. ncbi request reprint Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, Room 505, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 15:1614-9. 2006
  5. pmc Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Breast Cancer Res 8:R71. 2006
  6. ncbi request reprint IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    Breast Cancer Res Treat 99:1-7. 2006
  7. ncbi request reprint Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street Room 505, New York, NY 10032, USA
    World J Gastroenterol 11:6056-60. 2005
  8. ncbi request reprint MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
    Carcinogenesis 26:2131-7. 2005
  9. pmc Telomere length, oxidative damage, antioxidants and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Int J Cancer 124:1637-43. 2009
  10. ncbi request reprint Short telomere length and breast cancer risk: a study in sister sets
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Cancer Res 67:5538-44. 2007

Research Grants

Collaborators

Detail Information

Publications56

  1. pmc Genetic variation in telomere maintenance genes, telomere length and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e44308. 2012
    ..Telomeres at the ends of eukaryotic chromosomes play a critical role in maintaining the integrity and stability of the genome and participate in the initiation of DNA damage/repair responses...
  2. pmc Dysregulation of circulating microRNAs and prediction of aggressive prostate cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University Medical Center, New York, New York, USA
    Prostate 72:1469-77. 2012
    ..It is becoming increasingly evident that microRNAs (miRNAs) are associated with the development and progression of prostate cancer (PCa)...
  3. pmc Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 650 West 168th Street, Black Building 1608, New York, NY 10032, USA
    Breast Cancer Res Treat 134:393-400. 2012
    ..These data suggest that unfavorable genetic variants in telomere pathway genes may help to predict breast cancer survival...
  4. ncbi request reprint Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, Room 505, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 15:1614-9. 2006
    ..These findings suggest that those polymorphisms we have investigated to date in nucleotide excision repair pathway genes explain only a small amount of the variability in DRC...
  5. pmc Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Breast Cancer Res 8:R71. 2006
    ..926, COX-2 .5209, and COX-2 .8473) may reduce overall breast cancer risk or risk for subtypes of breast cancer by modulating the inflammatory response and may interact with aspirin or any NSAID use...
  6. ncbi request reprint IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    Breast Cancer Res Treat 99:1-7. 2006
    ..Additional studies focused on the biological function of the variant-G allele and interactions with other genetic polymorphisms are necessary to confirm our findings...
  7. ncbi request reprint Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street Room 505, New York, NY 10032, USA
    World J Gastroenterol 11:6056-60. 2005
    ..To explore the interaction models of the cytochrome P-450 (CYP) 1A1 Val variant and glutathione S-transferase (GST) M1 null polymorphisms with tobacco smoking in the occurrence of intestinal gastric cancer...
  8. ncbi request reprint MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
    Carcinogenesis 26:2131-7. 2005
    ....
  9. pmc Telomere length, oxidative damage, antioxidants and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Int J Cancer 124:1637-43. 2009
    ..01). These results provided the strongest evidence to date that breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements...
  10. ncbi request reprint Short telomere length and breast cancer risk: a study in sister sets
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Cancer Res 67:5538-44. 2007
    ..3; 95% CI, 0.5-3.6 for Q4 versus Q1). If these associations are replicated in larger studies, they provide modest epidemiologic evidence that shortened telomere length may be associated with breast cancer risk...
  11. ncbi request reprint Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:336-42. 2005
    ..Further understanding of the biological function of XRCC1 variants and their interactions with PAH-DNA adducts, antioxidants, and other genes in the pathway are needed...
  12. ncbi request reprint A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer
    Jing Shen
    Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Jiangsu Province, China
    World J Gastroenterol 10:3278-83. 2004
    ..The aim of this study was to determine whether iNOS C/T polymorphism was associated with increased susceptibility to gastric cancer...
  13. pmc Xeroderma pigmentosum complementation group C genotypes/diplotypes play no independent or interaction role with polycyclic aromatic hydrocarbons-DNA adducts for breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, P and S 19 418, New York, NY 10032, USA
    Eur J Cancer 44:710-7. 2008
    ..69). These data suggest that XPCs have neither independent effects nor interactions with cigarette smoking and PAH-DNA adducts for breast cancer risk. Further studies with multiple genetic polymorphisms in NER pathway are warranted...
  14. pmc Multiple genetic variants in telomere pathway genes and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, P and S 19 418, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 19:219-28. 2010
    ..To explore the etiologic role of genetic variants in telomere pathway genes and breast cancer risk...
  15. ncbi request reprint Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk
    Katherine D Crew
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 161 Fort Washington Avenue, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 16:2033-41. 2007
    ..Overall, this study suggests that the risk of breast cancer may be elevated among women with polymorphisms in NER pathway genes and detectable PAH-DNA adducts...
  16. ncbi request reprint TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population
    Guangfu Jin
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, 140 Hanzhong Road, 210029 Nanjing, China
    J Cancer Res Clin Oncol 134:345-51. 2008
    ..This population-based case-control study was to evaluate the contribution of functional polymorphisms in TGFB1 C-509T, Leu10Pro and TGFBR2 G-875A to the risk of esophageal squamous cell carcinoma (ESCC)...
  17. ncbi request reprint Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high-risk Chinese population
    Guangfu Jin
    Department of Epidemiology and Biostatistics, Cancer Research Center of Nanjing Medical University, Nanjing, China
    Cancer Sci 98:864-8. 2007
    ..55-0.82 for AGA; OR = 0.71, 95% CI = 0.57-0.88 for GGG and OR = 0.66, 95% CI = 0.52-0.84 for GAA, respectively). Our findings indicate that variant genotypes and haplotypes of EGF promoter might play a role in gastric carcinogenesis...
  18. ncbi request reprint [Study on the association between total plasma homocysteine levels, dietary habits and the risk of gastric cancer]
    Li na Wang
    Department of Epidemiology and Biostatistics, Cancer Research Center of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:528-31. 2007
    ..To explore the relationship between total plasma homocysteine (tHcy) levels, dietary habits and susceptibility of gastric cancer (CGC) in Yangzhong and Yixing cities, the two high GC risk areas in Jiangsu province...
  19. doi request reprint The role of IGFBP3 functional polymorphisms in the risk of gastric cancer in a high-risk Chinese population
    Wensen Chen
    Department of Epidemiology and Biostatistics, Cancer Research Center of Nanjing Medical University, Nanjing, China
    Eur J Cancer Prev 17:82-7. 2008
    ....
  20. ncbi request reprint Polymorphisms of MTHFD, plasma homocysteine levels, and risk of gastric cancer in a high-risk Chinese population
    Lina Wang
    Department of Epidemiology and Biostatistics, Institute of Toxicology, Nanjing Medical University, Nanjing, China
    Clin Cancer Res 13:2526-32. 2007
    ..The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase (MTHFR)...
  21. ncbi request reprint [Study on the Relationship between susceptibility of stomach neoplasm cancer and polymorphism of inducible nitric oxide synthase gene]
    Jing Shen
    Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
    Zhonghua Liu Xing Bing Xue Za Zhi 23:374-7. 2002
    ..To study the relationship between polymorphism of inducible Nitric Oxide Synthase (iNOS) gene and the susceptibility of intestinal type stomach cancer and stomach cardia cancer in Chinese people...
  22. ncbi request reprint DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer
    David O Kennedy
    Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
    J Natl Cancer Inst 97:127-32. 2005
    ..Interindividual differences in DNA repair capacity may influence cancer risk. We tested whether the nucleotide excision repair pathway was deficient in breast cancer case patients by analyzing sister pairs...
  23. ncbi request reprint Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population
    Guangfu Jin
    Department of Epidemiology and Biostatistics, Cancer Research Center of Nanjing Medical University, Nanjing, China
    Int J Cancer 120:1330-5. 2007
    ..44, 95% CI = 0.32-0.62). These findings indicate, for the first-time, that the functional variants in the promoter of TGFB1 and TGFBR2 might contribute to gastric cancer susceptibility...
  24. pmc Genome-wide aberrant DNA methylation of microRNA host genes in hepatocellular carcinoma
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY USA
    Epigenetics 7:1230-7. 2012
    ..Unexpectedly, miR-196b was significantly upregulated in tumor compared with non-tumor tissues (p = 0.0001). These data suggest that aberrant DNA methylation may lead to dysregulation of miR-10a in HCC tumor tissues...
  25. doi request reprint Potentially functional polymorphisms of the vascular endothelial growth factor gene and risk of gastric cancer
    Qiao Ke
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, Nanjing, China
    Mol Carcinog 47:647-51. 2008
    ..In conclusion, our data did not support a significant association between VEGF SNPs and the risk of GC...
  26. ncbi request reprint DNA adducts, DNA repair genotype/phenotype and cancer risk
    Regina M Santella
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th St, New York, NY 10032, USA
    Mutat Res 592:29-35. 2005
    ..Analysis of samples from these two studies have demonstrated the utility of measurement of DNA adducts as biomarkers of exposure and that DNA repair capacity, measured by genotyping or phenotyping, can influence risk...
  27. doi request reprint Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population
    Juan Wu
    Department of Epidemiology and Biostatistics, Cancer Center, Nanjing Medical University, Nanjing, China
    Mol Carcinog 48:626-32. 2009
    ..68, 95% CI = 0.46-0.99), compared with those carrying the GG genotype. Our results indicate that IL4 T-168C and IL2 G-330T promoter polymorphisms may contribute to the etiology of gastric cardia cancer in Chinese populations...
  28. pmc Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY, USA
    Epigenetics 8:34-43. 2013
    ..These results demonstrate the significance of aberrant DNA methylation in HCC tumorigenesis...
  29. doi request reprint Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-type gastric cancer in a Chinese population
    Yan Lu
    Department of Epidemiology and Biostatistics, Cancer Center, Nanjing Medical University, Nanjing, China
    Int J Cancer 127:2183-9. 2010
    ..83, 95% CI: 1.29-2.60 and OR = 1.84, 95% CI: 1.33-2.56, respectively). These findings provide further evidence supporting that the genetic variants of PSCA gene may contribute to the gastric carcinogenesis...
  30. ncbi request reprint E-cadherin gene C-160A promoter polymorphism and risk of non-cardia gastric cancer in a Chinese population
    Yan Lu
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, Nanjing 210029, Jiangsu Province, China
    World J Gastroenterol 11:56-60. 2005
    ..To test the hypothesis that E-cadherin gene (CDH1) C-160A promoter variant genotype is associated with an increased risk for developing gastric cancer...
  31. pmc Prognostic significance of gene-specific promoter hypermethylation in breast cancer patients
    Yoon Hee Cho
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th St, New York, NY 10032, USA
    Breast Cancer Res Treat 131:197-205. 2012
    ..002), although confidence intervals were wide. Our results suggest that promoter methylation, particularly for a panel of genes, has the potential to be used as a biomarker for predicting prognosis in breast cancer...
  32. pmc Silencing of Hint1, a novel tumor suppressor gene, by promoter hypermethylation in hepatocellular carcinoma
    Yu Jing Zhang
    Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 630 W 168th St, New York, NY 10032, USA
    Cancer Lett 275:277-84. 2009
    ..These results suggest that promoter hypermethylation of Hint1 may play a role in hepatocarcinogenesis...
  33. ncbi request reprint [Meta-analysis on the relationship between IL8-251 gene polymorphism and gastric cancer]
    Yan Lu
    Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
    Zhonghua Yu Fang Yi Xue Za Zhi 41:39-42. 2007
    ..To evaluate the relationship between IL8-251 gene polymorphisms and gastric cancer...
  34. ncbi request reprint Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population
    Lina Wang
    Department of Epidemiology and Biostatistics, School of Public Health, Cancer Research Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing, and Yixing People s Hospital, Yixing City, Jiangsu 210029, China
    Eur J Cancer 42:3206-11. 2006
    ..Further large and functional studies are needed to confirm our findings...
  35. pmc Genome-wide DNA methylation profiles in hepatocellular carcinoma
    Jing Shen
    Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
    Hepatology 55:1799-808. 2012
    ..At least one of these genes was hypermethylated in 87% of the cases, suggesting that measurement of DNA methylation in plasma samples is feasible...
  36. ncbi request reprint [The distributive features of three kinds of metabolic genes polymorphisms in population of Han nationality in south area of China]
    Jing Shen
    School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, 210029 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19:302-7. 2002
    ..To find out the distributive features of some metabolic genes polymorphisms in Han population of south area of China...
  37. pmc DNA methylation changes correlate with Gleason score and tumor stage in prostate cancer
    Lissette Delgado-Cruzata
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 650 West 168th Street, New York, NY 10032, USA
    DNA Cell Biol 31:187-92. 2012
    ..These data, although preliminary, suggest that aberrant methylation may be a useful marker to identify PCa patients with clinically aggressive disease...
  38. pmc Activated checkpoint kinase 2 expression and risk for oral squamous cell carcinoma
    Angela J Yoon
    College of Dental Medicine, Division of Oral and Maxillofacial Pathology, Columbia University Medical Center, 630 West 168th Street, PH15W 1562, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 16:2768-72. 2007
    ..Included in both groups were lesions with histologically confirmed dysplasia and those that lacked histologic evidence of atypia...
  39. pmc Expression of activated checkpoint kinase 2 and histone 2AX in exfoliative oral cells after exposure to ionizing radiation
    Angela J Yoon
    Columbia University College of Dental Medicine, Columbia University Medical Center, 630 West 168th Street, PH15W 1562, New York, NY 10032, USA
    Radiat Res 171:771-5. 2009
    ..Both biomarkers showed statistically significant increases in levels of expression after the radiation exposure (P < 0.001). This suggests that pChk2 and gamma-H2AX may serve as sensitive indicators of low-dose radiation exposure...
  40. ncbi request reprint Telomere length in hepatocellular carcinoma and paired adjacent non-tumor tissues by quantitative PCR
    Yujing Zhang
    Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, New York, New York, USA
    Cancer Invest 25:668-77. 2007
    ..The relationship between telomere length shortening, chemical carcinogen exposure, and genetic and epigenetic changes in hepatocarcinogenesis needs further investigation...
  41. ncbi request reprint Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA
    Yu Jing Zhang
    Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, New York 10032, USA
    Clin Cancer Res 13:2378-84. 2007
    ..We explored the possible diagnostic value of aberrant promoter hypermethylation of three tumor suppressor genes in serum DNA for early detection of HCC...
  42. doi request reprint Evaluation of environmental and personal susceptibility characteristics that modify genetic risks
    Jing Shen
    Dept of Environmental Health Sciences, Columbia University, New York, NY, USA
    Methods Mol Biol 471:163-77. 2009
    ..The role of genetic and epigenetic factors in cancer development is discussed. Preventive approaches, especially in the epigenetic field, show promise. A discussion about different epidemiological methods with examples is provided...
  43. ncbi request reprint [Heavy metal content and ecological risk warning assessment of vegetable soils in Chongming Island, Shanghai City]
    Jun Wang
    Key Laboratory of Geo information Science of the Ministry of Education, College of Resources and Environment Science, East China Normal University, Shanghai 200062, China
    Huan Jing Ke Xue 28:647-53. 2007
    ..562. The order of ecological risk was Baozhen town (I(ER) = 1.799) > Chengqiaozhen town (I(ER) = 1.636) > Chenjiazhen (I(ER) = 1.368). The three towns were all light warning situation...
  44. ncbi request reprint dUTP Pyrophosphatase, its appearance in extracellular compartment may serve as a potential biomarker for N-methyl-N'-nitro-N-nitrosoguanidine exposure in mammalian cells
    Meiping Wu
    Department of Pathology and Pathophysiology, Center for Environmental Genomics, Zhejiang University School of Medicine, 353 Yan An Road, Hangzhou, Zhejiang 310031, P R China
    Proteomics 6:3001-7. 2006
    ..The appearance of DUT-N in culture medium and its down-regulation in cell lysate was confirmed by Western blot. These data suggest that these proteins, especially DUT-N, could be used as candidate biomarkers for monitoring MNNG exposure...
  45. ncbi request reprint Preliminary study on proteomics of gastric carcinoma and its clinical significance
    Hong Gang Qian
    Department of Surgery, Peking University School of Clinical Oncology, Beijing Cancer Hospital, Haidian District, Beijing 100036, China
    World J Gastroenterol 11:6249-53. 2005
    ..To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer...
  46. pmc Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history
    Zhuoqi Liu
    Peking University School of Oncology and Beijing Institute for Cancer Research and Beijing Cancer Hospital, Hai Dian District, Beijing, 100036, PR China
    BMC Microbiol 8:81. 2008
    ..H. pylori infection was determined by H. pylori-specific 23S rRNA PCR, ELISA, and13C-urea breath test assays. Mutations of the 23S rRNA gene were detected by RFLP assays...
  47. ncbi request reprint Epidemics of type 1 diabetes in China
    Ze Yang
    Institute of Geriatrics, Ministry of Health, Beijing, China
    Pediatr Diabetes 6:122-8. 2005
    ..A Poisson regression model with a sine wave function was applied to evaluate the seasonal trends. A scan statistic was used to examine the occurrence of an epidemic...
  48. ncbi request reprint Involvement of the nitric oxide-cyclic GMP pathway and neuronal nitric oxide synthase in ATP-induced Ca2+ signalling in cochlear inner hair cells
    Jing Shen
    Hearing Research Laboratory, Department of Otolaryngology, Kansai Medical University, Fumizonocho 10 15, Moriguchi, Osaka 570 8507, Japan
    Eur J Neurosci 21:2912-22. 2005
    ..Thereafter, NO can be produced and conversely inhibits the Ca(2+) influx via the NO-cGMP-PKG pathway by a feedback mechanism...
  49. ncbi request reprint Crocetin inhibits mRNA expression for tumor necrosis factor-alpha, interleukin-1beta, and inducible nitric oxide synthase in hemorrhagic shock
    Rongjie Yang
    Department of Surgery, Shock Trauma Research Center, University of Missouri Kansas City, Kansas City, Missouri, USA
    JPEN J Parenter Enteral Nutr 30:297-301. 2006
    ....
  50. ncbi request reprint Diagnosis of gastric cancer using decision tree classification of mass spectral data
    Yahui Su
    Peking University School of Oncology and Beijing Cancer Hospital and Institute, Haidian, Beijing, China
    Cancer Sci 98:37-43. 2007
    ..Therefore, the decision tree analysis of serum proteomic patterns has the potential to be used in gastric cancer diagnosis...
  51. doi request reprint The synergistic reversal effect of multidrug resistance by quercetin and hyperthermia in doxorubicin-resistant human myelogenous leukemia cells
    Jing Shen
    Affiliated Hospital, Academy of Military Medical Sciences, Beijing, China
    Int J Hyperthermia 24:151-9. 2008
    ..This study aimed to evaluate the multidrug resistance (MDR) reversal activity of quercetin (Que) in combination with hyperthermia (HT) in human myelogenous leukemia cells K562/A...
  52. ncbi request reprint Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea
    Hiroko Takeda-Nakazawa
    Hearing Research Laboratory, Department of Otolaryngology, Kansai Medical University, Fumizonocho 10 15, Moriguchi, Osaka 570 8507, Japan
    Hear Res 227:59-70. 2007
    ..NO conversely inhibits the Ca(2+) response via the NO-cGMP-PKG pathway by a feedback mechanism...
  53. ncbi request reprint A serum proteomic pattern for the detection of colorectal adenocarcinoma using surface enhanced laser desorption and ionization mass spectrometry
    Xing Pan Liu
    Department of Surgery, Beijing Cancer Hospital, School of Oncology, Peking University, Beijing, China
    Cancer Invest 24:747-53. 2006
    ....
  54. ncbi request reprint [Heavy metals accumulation in river sediments of Chongming Island, Shanghai City, and its environmental risk]
    Jun Wang
    Key Laboratory of Geographic Information Science of Education Ministry, School of Resources and Environment Science, East China Normal University, Shanghai 200062, China
    Ying Yong Sheng Tai Xue Bao 18:1518-22. 2007
    ....
  55. doi request reprint Proteomic analysis of different temporal expression patterns induced by N-methyl-N'-nitro-N-nitrosoguanidine treatment
    Jing Shen
    Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou 310058, China
    J Proteome Res 7:2999-3009. 2008
    ..We also carried out a network analysis of these proteins and the data suggest a central role for some key regulators in different pathways...
  56. ncbi request reprint Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea
    Hiroko Takeda-Nakazawa
    Hearing Research Laboratory, Department of Otolaryngology, Kansai Medical University, Fumizonocho 10 15, Moriguchi, Osaka 570 8507, Japan
    Hear Res 230:93-104. 2007
    ..NO conversely inhibits the Ca2+ response via the NO-cGMP-PKG pathway by a feedback mechanism...

Research Grants1