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| L SaimanSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Risk factors for hospital-acquired infections in the neonatal intensive care unitLisa Saiman
Division of Infectious Diseases, Department of Pediatrics, Columbia University, New York, NY 10032, USA
Semin Perinatol 26:315-21. 2002..An understanding of the risk factors that are associated with hospital-acquired infections is essential to design preventive strategies...
Infection control in cystic fibrosis: barriers to implementation and ideas for improvementLisa Saiman
Division of Infectious Diseases, Department of Pediatrics, Columbia University, New York, NY 10032, USA
Curr Opin Pulm Med 15:626-31. 2009..In addition, controversies regarding optimal infection control will be discussed. Finally, suggestions to improve infection control in CF will be proposed...- Open-label, follow-on study of azithromycin in pediatric patients with CF uninfected with Pseudomonas aeruginosaLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Pediatr Pulmonol 47:641-8. 2012..We now report the results of the open-label, follow-on study to assess durability of response to azithromycin and continued safety and tolerability... 
Adherence with tobramycin inhaled solution and health care utilizationBecky A Briesacher
University of Massachusetts Medical School and Meyers Primary Care Institute, Worcester, MA, USA
BMC Pulm Med 11:5. 2011..Adherence with tobramycin inhalation solution (TIS) during routine cystic fibrosis (CF) care may differ from recommended guidelines and affect health care utilization...- The mycobacteriology of non-tuberculous mycobacteriaLisa Saiman
Columbia University, New York, NY 10032, USA
Paediatr Respir Rev 5:S221-3. 2004..Pulsed- field gel electrophoresis is the method of choice to determine strain relatedness. At present, susceptibility testing for non-tuberculous mycobacteria is not fully standardised and has not been correlated with clinical outcomes... - Infection control in cystic fibrosisLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Clin Microbiol Rev 17:57-71. 2004..It will be critical to measure the dissemination, implementation, and potential impact of these guidelines to monitor changes in practice and reduction in infections... - Clinical utility of synergy testing for multidrug-resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis: 'the motion for'Lisa Saiman
Division of Infectious Diseases, Department of Pediatrics, Columbia University, New York, New York 10032, USA
Paediatr Respir Rev 8:249-55. 2007..Synergy testing has also been advocated for isolates from patients failing to respond to therapy for treatment of a pulmonary exacerbation or from patients with substantial drug allergies for whom antibiotic choices are limited... - Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum womenLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Clin Infect Dis 37:1313-9. 2003..We report that MW2, which was previously limited to the midwestern United States, has spread to the northeastern United States and has become a health care-associated pathogen... - Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trialLisa Saiman
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032 3784, USA
JAMA 290:1749-56. 2003..Treatment strategies for cystic fibrosis (CF) lung disease include antibiotics, mucolytics, and anti-inflammatory therapies. Increasing evidence suggests that macrolide antibiotics might be beneficial in patients with CF... - Evaluation of MicroScan Autoscan for identification of Pseudomonas aeruginosa isolates from cystic fibrosis patientsLisa Saiman
Department of Pediatrics, Division of Infectious Diseases, Columbia University, New York, New York 10032, USA
J Clin Microbiol 41:492-4. 2003..Extending the incubation to 48 h improved identification, but 15% of isolates remained misidentified. The MicroScan Autoscan system cannot be recommended for the identification of P. aeruginosa isolates from CF patients... - Microbiology of early CF lung diseaseLisa Saiman
Columbia University, New York 10032, USA
Paediatr Respir Rev 5:S367-9. 2004..aeruginosa from the lower airway was unlikely, but a positive culture did not predict lower airway infection. Similar findings were noted for H. influenzae and S. aureus... - The use of macrolide antibiotics in patients with cystic fibrosisLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Curr Opin Pulm Med 10:515-23. 2004..There has been much recent interest in the use of macrolide antibiotics as chronic suppressive therapy in patients with cystic fibrosis. Three recent randomized, placebo-controlled trials have been conducted... - Strategies for prevention of nosocomial sepsis in the neonatal intensive care unitLisa Saiman
Columbia University, Department of Pediatrics, Division of Infectious Diseases, New York 10032, USA
Curr Opin Pediatr 18:101-6. 2006.... - Heterogeneity of treatment response to azithromycin in patients with cystic fibrosisLisa Saiman
Department of Pediatics, Columbia University, NY 10032, USA
Am J Respir Crit Care Med 172:1008-12. 2005..2% improvement in the 168-d relative change in FEV1 among azithromycin participants compared with placebo participants... - Providing a safety net for children: investigating a multistate outbreak of Ralstonia mannitolilytica related to a contaminated reusable deviceLisa Saiman
Department of Pediatrics, Columbia University, New York, New York, USA
Pediatrics 119:1207-9. 2007 - Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosisL Saiman
Department of Pediatrics, Columbia University, 650 West 168th St, New York, NY 10032, USA
Antimicrob Agents Chemother 45:2838-44. 2001..The tested cathelicidin-derived peptides represent a novel class of antimicrobial agents and warrant further development as prophylactic or therapeutic agents for CF lung disease... - Effect of azithromycin on pulmonary function in patients with cystic fibrosis uninfected with Pseudomonas aeruginosa: a randomized controlled trialLisa Saiman
Columbia University, Department of Pediatrics, 650 W 168th St, PH 4 West, Room 420, New York, NY 10032, USA
JAMA 303:1707-15. 2010..Azithromycin is recommended as therapy for cystic fibrosis (CF) patients with chronic Pseudomonas aeruginosa infection, but there has not been sufficient evidence to support the benefit of azithromycin in other patients with CF... - Infection prevention and control in cystic fibrosisLisa Saiman
Department of Pediatrics, Columbia University, and Morgan Stanley Children s Hospital of NewYork Presbyterian, New York, New York 10032, USA
Curr Opin Infect Dis 24:390-5. 2011.... - Identification and antimicrobial susceptibility of Alcaligenes xylosoxidans isolated from patients with cystic fibrosisL Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
J Clin Microbiol 39:3942-5. 2001..xylosoxidans from other CF pathogens. Standards for processing CF specimens should be developed, and the optimal method for antimicrobial susceptibility testing of A. xylosoxidans should be determined... - Prevalence of infectious diseases among internationally adopted childrenL Saiman
Department of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
Pediatrics 108:608-12. 2001..Internationally adopted children are at increased risk of infections acquired in their country of origin. Ongoing surveillance of this unique population is needed to detect changing epidemiology and provide appropriate care... - Molecular epidemiology of staphylococcal scalded skin syndrome in premature infantsL Saiman
Department of Pediatrics, Columbia University and Columbia Presbyterian Medical Center, New York, NY 10032, USA
Pediatr Infect Dis J 17:329-34. 1998..We describe two cases of SSSS in very low birth weight infants in a neonatal intensive care unit (NICU) and the success of infection control strategies used to prevent an outbreak... - Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study groupL Saiman
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Pediatr Infect Dis J 19:319-24. 2000..Candida species are important nosocomial pathogens in neonatal intensive care unit (NICU) patients... - Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosisLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Antimicrob Agents Chemother 46:1105-7. 2002.... - Risk factors for latent tuberculosis infection among children in New York CityL Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Pediatrics 107:999-1003. 2001.... - Evaluation of reference dilution test methods for antimicrobial susceptibility testing of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosisL Saiman
Department of Pediatrics and Clinical Microbiology, Columbia University, New York, New York 10032, USA
J Clin Microbiol 37:2987-91. 1999..Thus, this broth microdilution assay can serve as a reference method and facilitate future studies to determine the optimal method for antibiotic susceptibility testing of CF strains... - Risk factors for Candida species colonization of neonatal intensive care unit patientsL Saiman
Department of Pediatrics, Columbia University, New York, NY, USA
Pediatr Infect Dis J 20:1119-24. 2001..particularly C. parapsilosis, from the hands of health care workers. H2 blockers, third generation cephalosporins and delayed enteral feedings alter gastrointestinal tract ecology, thereby facilitating colonization... - Comparison of agar diffusion methodologies for antimicrobial susceptibility testing of Pseudomonas aeruginosa isolates from cystic fibrosis patientsJ L Burns
Department of Pediatrics, Division of Infectious Disease, University of Washington, Seattle, Washington, USA
J Clin Microbiol 38:1818-22. 2000..1 and 2.2% major errors (false resistance). Overall, both agar diffusion methods appear to be broadly acceptable for routine clinical use in susceptibility testing of CF isolates of P. aeruginosa... - Comparison of two commercial systems (Vitek and MicroScan-WalkAway) for antimicrobial susceptibility testing of Pseudomonas aeruginosa isolates from cystic fibrosis patientsJ L Burns
Department of Pediatrics, Division of Infectious Disease, Children s Hospital and Regional Medical Center, University of Washington, P O Box 5371 CH 32, Seattle, WA 98105 0371, USA
Diagn Microbiol Infect Dis 39:257-60. 2001.... - Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. The National Epidemiology of Mycosis SurveyH M Blumberg
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicinel, Atlanta, GA 30303, USA
Clin Infect Dis 33:177-86. 2001..3). Prospective clinical studies are needed to identify which antifungal agents are most protective and which high-risk patients will benefit from antifungal prophylaxis... - Predictors and outcomes for pregnant women with vaginal-rectal carriage of community-associated methicillin-resistant Staphylococcus aureusKatherine T Chen
Department of Obstetrics and Gynecology, Columbia University, New York, New York 10032, USA
Am J Perinatol 24:235-40. 2007..Additional microbiologic studies and epidemiologic studies are needed to clarify the relationship between S. aureus and GBS, given that these two colonizing organisms have the potential to become pathogens... - Respiratory microbiology of patients with cystic fibrosis in the United States, 1995 to 2005Samiya Razvi
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Chest 136:1554-60. 2009..Numerous improvements in diagnostic and therapeutic strategies for patients with cystic fibrosis (CF) have occurred during the past 2 decades. We hypothesized that these changes could impact trends in respiratory microbiology... - Gram-negative bacilli associated with catheter-associated and non-catheter-associated bloodstream infections and hand carriage by healthcare workers in neonatal intensive care unitsElaine L Larson
Department of Pediatrics, School of Nursing, Columbia University, New York, NY, USA
Pediatr Crit Care Med 6:457-61. 2005..Clean hands of providers are an unlikely source of endemic Gram-negative bacilli, suggesting that prevention strategies should focus more on control of endogenous neonatal flora or environmental sources... - The epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit, 2000-2007A J Carey
Department of Pediatrics, Division of Neonatology, Columbia University, New York, NY 10032, USA
J Perinatol 30:135-9. 2010..aureus (MRSA) infections in a neonatal intensive care unit (NICU).Study Design:A retrospective chart review was conducted from 2000-2007; demographic and clinical characteristics of infected infants and crude mortality were assessed... - An outbreak of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unitLisa Saiman
Department of Pediatrics Columbia University and New York Presbyterian Medical Center, Children's Hospital of New York, New York, New York 10032, USA
Infect Control Hosp Epidemiol 24:317-21. 2003..MRSA appears to have been transferred from our adult facility to our pediatric facility by a rotating HCW. Spa typing allowed comparison of our institution's MRSA strains with previously characterized outbreak clones... - Outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit linked to artificial nailsArchana Gupta
Department of Pediatrics, Columbia University, New York-Presbyterian Hospital, New York, New York 10032, USA
Infect Control Hosp Epidemiol 25:210-5. 2004..87; CI95, 1.75 to 35.36) were associated with infection or colonization with clone A. CONCLUSION: Short, well-groomed, natural nails should be mandatory for HCWs with direct patient contact.. - Safety and tolerability of linezolid in childrenLisa Saiman
Columbia University, New York, NY, USA
Pediatr Infect Dis J 22:S193-200. 2003..CONCLUSIONS: Linezolid was safe and well-tolerated in pediatric patients with community-acquired pneumonia, otitis media, SSSIs and infections caused by Gram-positive resistant pathogens... - Nonsusceptible Streptococcus pneumoniae in children with chronic otitis media with effusion and recurrent otitis media undergoing ventilating tube placementJ Haddad
Division of Pediatric Otolaryngology Head and Neck Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Pediatr Infect Dis J 19:432-7. 2000..If these children undergo ventilating tube placement, there is an opportunity to culture middle ear fluid and the nasopharynx to determine carriage of NSP... - Concordance of Gastrointestinal Tract Colonization and Subsequent Bloodstream Infections With Gram-negative Bacilli in Very Low Birth Weight Infants in the Neonatal Intensive Care UnitAnn Smith
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA
Pediatr Infect Dis J 29:831-5. 2010.... - Antimicrobial resistance patterns of colonizing flora on nurses' hands in the neonatal intensive care unitHeather A Cook
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Infect Control 35:231-6. 2007..The purpose of this study was to examine effects of hand hygiene product and skin condition on the antimicrobial resistance patterns of colonizing hand flora among nurses... - Epidemiology of methicillin-susceptible Staphylococcus aureus in the neonatal intensive care unitPhilip L Graham
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Infect Control Hosp Epidemiol 23:677-82. 2002..Future studies should address cost-effective surveillance strategies for endemic infections... - Epidemiology of enterococci in a neonatal intensive care unitJennifer Duchon
College of Physicians and Surgeons of Columbia University, New York, New York, USA
Infect Control Hosp Epidemiol 29:374-6. 2008..Surveillance triggered by even a single clinical culture positive for VRE may be justified in the neonatal intensive care unit, because a single culture result may represent a large hidden reservoir of VRE-colonized infants... - Nosocomial rotavirus in a pediatric hospitalA J Ratner
Department of Pediatrics, Babies and Children's Hospital of New York, New York-Presbyterian Medical Center, Columbia University, College of Physicians and Surgeons, New York City, USA
Infect Control Hosp Epidemiol 22:299-301. 2001..Improved compliance with infection control and case-finding among patients and healthcare workers halted the outbreak... - Nosocomial transmission of methicillin-resistant Staphylococcus aureus from a mother to her preterm quadruplet infantsAnne-Sophie Morel
Department of Pediatrics, Division of Infectious Diseases and New York-Presbyterian Hospital, Columbia University, New York, NY 10032, USA
Am J Infect Control 30:170-3. 2002..CONCLUSIONS: Use of gowns and gloves by the family members of women with multiple gestations should be recommended to prevent transmission of potential pathogens in the NICU... - Risk factors for candidemia in critically ill infants: a matched case-control studyKristina N Feja
Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA
J Pediatr 147:156-61. 2005.... - Evaluation and treatment of neonates with suspected late-onset sepsis: a survey of neonatologists' practicesLorry G Rubin
Department of Pediatrics, Schneider Children's Hospital of the North Shore-Long Island Jewish Health System, New Hyde Park, New York, USA
Pediatrics 110:e42. 2002.... - Epidemiology and diagnosis of hospital-acquired conjunctivitis among neonatal intensive care unit patientsJanet Haas
Columbia University School of Nursing, New York, NY, USA
Pediatr Infect Dis J 24:586-9. 2005..The NNIS definition failed to detect 38% of clinical infections. Consideration should be given to revising the definition of conjunctivitis for the NICU population... - Update on the epidemiology and management of Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus, in patients with cystic fibrosisAnne Stone
Department of Pediatrics, Division of Pediatric Pulmonary Medicine, Morgan Stanley Children s Hospital of New York Presbyterian Hospital, New York, New York 10032, USA
Curr Opin Pulm Med 13:515-21. 2007..aureus... - Hospital-acquired infections in the NICU: epidemiology for the new millenniumAlison J Carey
Division of Neonatology, Columbia University Medical Center, New York Presbyterian Hospital, 3959 Broadway, CHC 115, New York, NY 10032, USA
Clin Perinatol 35:223-49, x. 2008..This review focuses on two major pathogens that cause nosocomial infection, Candida and methicillin-resistant Staphylococcus aureus. The difficult diagnosis of meningitis in the neonate also is discussed... - Infection control recommendations for patients with cystic fibrosis: microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmissionLisa Saiman
Department of Pediatrics, Columbia University, New York, New York, USA
Infect Control Hosp Epidemiol 24:S6-52. 2003 - Attributable costs and length of stay of an extended-spectrum beta-lactamase-producing Klebsiella pneumoniae outbreak in a neonatal intensive care unitPatricia W Stone
School of Nursing, Columbia University, New York, New York, 10032, USA
Infect Control Hosp Epidemiol 24:601-6. 2003..Further research is needed to estimate the societal costs of these infections and the cost-effectiveness of preventive interventions... - Risk factors for late-onset health care-associated bloodstream infections in patients in neonatal intensive care unitsSharon E Perlman
Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Infect Control 35:177-82. 2007.... - Molecular epidemiology of gram-negative bacilli from infected neonates and health care workers' hands in neonatal intensive care unitsValerie Waters
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Clin Infect Dis 38:1682-7. 2004..In contrast, only 9% of strains that caused infections were cultured from nurses' hands. These data suggest that practices in addition to hand hygiene are needed to prevent horizontal transmission of GNB in the NICU... - Antimicrobial susceptibility and synergy studies of Stenotrophomonas maltophilia isolates from patients with cystic fibrosisPablo San Gabriel
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Antimicrob Agents Chemother 48:168-71. 2004..To determine appropriate treatment for patients with CF, it is important to monitor the prevalence, antimicrobial susceptibility, and clinical impact of S. maltophilia in this patient population... - Colistin susceptibility testing: evaluation of reliability for cystic fibrosis isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophiliaSamuel M Moskowitz
Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA
J Antimicrob Chemother 65:1416-23. 2010..To assess the reliability of four standard testing methods, this pilot study used a challenge set that included polymyxin-resistant isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia... - Development of a statewide collaborative to decrease NICU central line-associated bloodstream infectionsJ Schulman
Department of Pediatrics Newborn Medicine, Weill Cornell Medical College, Weill Cornell Medical Center, New York, NY, USA
J Perinatol 29:591-9. 2009.... - Persistence of immunity to varicella-zoster virus after vaccination of healthcare workersL Saiman
Department of Pediatrics, Columbia University, College of Phyicians and Surgeons, New York City, New York 10032, USA
Infect Control Hosp Epidemiol 22:279-83. 2001..CONCLUSIONS: The VZV vaccine effectively protected HCWs from varicella, particularly from serious disease. Currently available serological tests are not optimal, and improved assays are needed... - Epidemiology of nontuberculous mycobacteria in patients without HIV infection, New York CityEthan E Bodle
Columbia University, New York, New York, USA
Emerg Infect Dis 14:390-6. 2008..avium complex (MAC) (27%, (p < 0.01). NTM disease in patients without HIV is increasing. Laboratory-based surveillance may be useful for detecting non-MAC and non-respiratory tract disease... - The gastrointestinal tract serves as the reservoir for Gram-negative pathogens in very low birth weight infantsPhilip L Graham
Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA
Pediatr Infect Dis J 26:1153-6. 2007..Ninety-five percent (18 of 19) of paired bloodstream infection or antecedent rectal cultures were genotypically concordant. The gastrointestinal tract is the reservoir for most cases of Gram-negative sepsis in this population... - In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosisYunhua Chen
Department of Pediatrics, Columbia University, 622 West 168th St, PH4W-470, New York, NY 10032, USA
Antimicrob Agents Chemother 49:2510-1. 2005..Doripenem had somewhat better activity than established antimicrobial agents... - Effect of antiseptic handwashing vs alcohol sanitizer on health care-associated infections in neonatal intensive care unitsElaine L Larson
School of Nursing, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, 630 W 168th Street, New York, NY 10032, USA
Arch Pediatr Adolesc Med 159:377-83. 2005.... - Molecular epidemiology of Serratia marcescens outbreaks in two neonatal intensive care unitsVladana Milisavljevic
Department of Pediatrics, School of Nursing, Columbia University, New York, New York, USA
Infect Control Hosp Epidemiol 25:719-21. 2004..Sinks did not harbor the outbreak strains. Antimicrobial susceptibility patterns did not prove to be an accurate predictor of strain relatedness for S. marcescens... - Validation of a multicenter computer-based surveillance system for hospital-acquired bloodstream infections in neonatal intensive care departmentsPhilip L Graham
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Am J Infect Control 32:232-4. 2004..The sensitivity (84%), specificity (99%), and positive (84%) and negative (99%) predictive values of NYARP were excellent when coagulase-negative staphylococcal bloodstream infections were removed... - Linezolid treatment of vancomycin-resistant Enterococcus faecium ventriculitisPhilip L Graham
Departments of Pediatrics and Epidemiology, Columbia, University, New York, NY 10032, USA
Pediatr Infect Dis J 21:798-800. 2002..The patient tolerated the therapy without adverse effects... - Epidemiology of candidemia at a Children's hospital, 2002 to 2006Natalie Neu
Departments of Pediatrics, Columbia University Medical Center, New York, New York, USA
Pediatr Infect Dis J 28:806-9. 2009..There are few recent studies evaluating trends in the epidemiology of candidemia including changes in species or utilization of antifungal agents in children... - Antibiotic use in neonatal intensive care units and adherence with Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial ResistanceSameer J Patel
Division of Infectious Diseases, Department of Pediatrics, Columbia University, New York, NY, USA
Pediatr Infect Dis J 28:1047-51. 2009.... - Staphylococcus aureus nasal colonization among pediatric cystic fibrosis patients and their household contactsAnne Stone
Division of Pediatric Pulmonology, Department of Pediatrics, Columbia University, New York, NY, USA
Pediatr Infect Dis J 28:895-9. 2009..Little is known about the prevalence of Staphylococcus aureus nasal colonization and the epidemiology of methicillin-susceptible and methicillin-resistant S. aureus (MRSA) among cystic fibrosis (CF) patients and their household members... - Changes in the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unitAlison J Carey
Department of Pediatrics, Division of Neonatology, Drexel University College of Medicine, St Christopher s Hospital For Children, Philadelphia, Pennsylvania 19134, USA
Infect Control Hosp Epidemiol 31:613-9. 2010..To determine whether the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) had changed in a level III neonatal intensive care unit (NICU)... - Pulmonary infections in patients with cystic fibrosisSujatha Rajan
Department of Pediatrics, Division of Pediatric Infectious Diseases, Columbia University, New York, NY 10032, USA
Semin Respir Infect 17:47-56. 2002..Novel strategies to disrupt biofilm formation, stimulate chloride conductance, and replace abnormal CFTR are currently being studied... - Completeness of pediatric TB reporting in New York CityPablo San Gabriel
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Public Health Rep 118:144-53. 2003..Hospital-based sources were used to develop alternative surveillance to assess completeness of reporting for pediatric TB in northern Manhattan and Harlem from 1993 through 1995... - Genetic relatedness of Staphylococcus epidermidis from infected infants and staff in the neonatal intensive care unitVladana Milisavljevic
Department of Pediatrics, Columbia University, New York, NY, USA
Am J Infect Control 33:341-7. 2005..epidermidis isolates were shared between infants and nurses. Hand hygiene alone is inadequate to prevent S. epidermidis infections, and additional strategies are needed to prevent cross transmission in NICU populations... - Risk factors for late onset gram-negative sepsis in low birth weight infants hospitalized in the neonatal intensive care unitPhilip L Graham
Department of Pediatrics, Columbia University, New York Presbyterian Hospital, New York, NY, USA
Pediatr Infect Dis J 25:113-7. 2006..We investigated risk factors for late onset Gram-negative sepsis in very low birth weight (<1500 g) NICU patients... - A review of antimicrobial control strategies in hospitalized and ambulatory pediatric populationsSameer J Patel
Department of Pediatrics, Division of Pediatric Infectious Diseases, New York Presbyterian Hospital, New York, NY 10032, USA
Pediatr Infect Dis J 26:531-7. 2007..Thus, it is difficult to determine the most effective interventions. Future studies should be designed to overcome the biases encountered in current publications... - Prevalence of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in pregnant womenKatherine T Chen
Department of Obstetrics and Gynecology and Epidemiology, Columbia University, New York, New York 10032, USA
Obstet Gynecol 108:482-7. 2006..To estimate the extent of Staphylococcus aureus vaginal-rectal colonization among pregnant women as severe S aureus infections have emerged in pregnant and postpartum women and infants... - Effectiveness of barrier precautions and surveillance cultures to control transmission of multidrug-resistant organisms: a systematic review of the literatureSally W Aboelela
Center for Interdisciplinary Research on Antimicrobial Resistance, Columbia University School of Nursing, New York, NY 10032, USA
Am J Infect Control 34:484-94. 2006..We focused on control measures that have a great potential to affect patient care, patient services, and hospital cost/resources: barrier precautions/patient isolation and surveillance cultures... - Nontuberculous mycobacterial infections in pediatric hematopoietic stem cell transplant recipients: case report and review of the literatureOuzama Nicholson
Department of Pediatrics, Columbia University, New York, NY, USA
Pediatr Infect Dis J 25:263-7. 2006..We reviewed NTM infections among pediatric HSCT patients at our institution from 2000-2004 and identified 2 additional cases. Fourteen published case reports of NTM disease in children are reviewed... - Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patientsThor Wagner
Department of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, NY, USA
Chest 128:912-9. 2005..This effect is less predictable against CIs than the prototypic strain PAO1... - Novel influenza A(H1N1) in a pediatric health care facility in New York City during the first wave of the 2009 pandemicYolanda Miroballi
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Arch Pediatr Adolesc Med 164:24-30. 2010..To describe the burden of care experienced by our pediatric health care facility in New York, New York, from May 3, 2009, to July 31, 2009, during the novel influenza A(H1N1) pandemic that began in spring 2009... - A survey of latent tuberculosis infection among laboratory healthcare workers in New York CityElizabeth Garber
TB study group, Division of Infectious Diseases, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Infect Control Hosp Epidemiol 24:801-6. 2003..Only one HCW had been treated for active TB. CONCLUSIONS: The prevalence of positive TSTs was high among laboratory HCWs, but the TST conversion rate was low. Higher rates of treatment for latent TB infection are desirable... - Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosisJuyan Zhou
Division of Infectious Diseases, Department of Pediatrics, Columbia University, College of Physicians and Surgeons, 650 West 168th Street, PH 4 West Room 470, New York, NY 10032, USA
Antimicrob Agents Chemother 51:1085-8. 2007..Minocycline, meropenem, and ceftazidime were the most active, inhibiting 38%, 26%, and 23% of strains, respectively. Synergy was rarely noted (range, 1% to 15% of strains per antibiotic combination)... - Compliance of clinical microbiology laboratories in the United States with current recommendations for processing respiratory tract specimens from patients with cystic fibrosisJuyan Zhou
Division of Infectious Diseases, Department of Pediatrics, Columbia University, College of Physicians and Surgeons, 650 West 168th St, PH 4 West Room 470, New York, NY 10032, USA
J Clin Microbiol 44:1547-9. 2006..Standardizing laboratory practices will improve treatment, infection control, and our understanding of the changing epidemiology of CF microbiology... - Survey of infection control policies for patients with cystic fibrosis in the United StatesJuyan Zhou
Department of Pediatrics, Columbia University, New York, NY 10032, USA
Am J Infect Control 36:220-2. 2008..Although routine mask use by patients remains an unresolved issue, many policies advocated this practice. Future studies should address barriers to implementation of these evidence-based guidelines and continue to monitor implementation... - Nosocomial transmission of Mycobacterium tuberculosis in a children's hospitalE H Lee
Department of Pediatrics, Children's Hospital of New York-Presbyterian, New York, USA
Int J Tuberc Lung Dis 9:689-92. 2005..adult facilities, including the importance of screening the adult visitors of children admitted with suspected TB... - Plesiomonas shigelloides sepsis and splenic abscess in an adolescent with sickle-cell diseaseK Ampofo
Division of Pediatric Infectious Diseases, The Children's Hospital of New York, New York-Presbyterian Medical Center, New York, NY, USA
Pediatr Infect Dis J 20:1178-9. 2001..Despite the high mortality rate reported in extraintestinal P. shigelloides infection, the patient survived after drainage of the abscess and treatment with antibiotics... - Hospital-acquired infections in the neonatal intensive care unit. IntroductionLisa Saiman
Semin Perinatol 26:313-4. 2002 - Infection control recommendations for patients with cystic fibrosis: Microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmissionLisa Saiman
Am J Infect Control 31:S1-62. 2003 - Factors associated with hand hygiene practices in two neonatal intensive care unitsBevin Cohen
Oceanside High School, Oceanside, NY, USA
Pediatr Infect Dis J 22:494-9. 2003..In this study use of an alcohol-based product was associated with significantly improved hand hygiene and should be encouraged, as recommended in the new CDC hand hygiene guideline... - Impact of staffing on bloodstream infections in the neonatal intensive care unitJeannie P Cimiotti
Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, Philadelphia, 19104 6096, USA
Arch Pediatr Adolesc Med 160:832-6. 2006..To examine the association between registered nurse staffing and healthcare-associated bloodstream infections in infants in the neonatal intensive care unit (NICU)... - Prevalence and clinical relevance of Staphylococcus warneri in the neonatal intensive care unitJeannie P Cimiotti
Center for Health Outcomes and Policy Research, Philadelphia, PA 19104, USA
Infect Control Hosp Epidemiol 28:326-30. 2007..To describe the prevalence of Staphylococcus warneri on the hands of nurses and the clinical relevance of this organism among neonates in the neonatal intensive care unit (NICU)... - Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypesDao Nguyen
Children s Hospital and Regional Medical Center, Seattle, Washington, USA
Pediatr Pulmonol 42:533-41. 2007..The in vitro effect of AZM on PLC correlates with FEV(1) response to AZM. This suggests that AZM anti-virulence effects may be predictive of clinical response and play a role in the mechanism of action of AZM in CF patients... - A low incidence of nontuberculous mycobacterial infections in pediatric hematopoietic stem cell transplantation recipientsElif Unal
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Biol Blood Marrow Transplant 12:1188-97. 2006..Multicenter studies are needed to identify the risk factors, early diagnostic criteria, and optimal therapy... - Bloodstream infections in patients given treatment with intravenous prostanoidsAlexander J Kallen
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Infect Control Hosp Epidemiol 29:342-9. 2008..An investigation was conducted to determine rates of prostanoid-associated BSI in this patient population and possible risk factors for infection... - The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosisJeffrey L Blumer
Rainbow Babies and Children s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Chest 128:2336-46. 2005.... - Perspectives on antimicrobial resistance: establishing an interdisciplinary research approachElaine L Larson
School of Nursing and Mailman School of Public Health, USA
Am J Infect Control 33:410-8. 2005
Research Grants
- Applied Research in Antimicrobial Resistance: Studies of Susceptibility TestingLisa Saiman; Fiscal Year: 2007..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
- Improving Antimicrobial Prescribing Practices in the Neonatal Intensive Care UnitLisa Saiman; Fiscal Year: 2009..abstract_text> ..
- Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB InfectionsLisa Saiman; Fiscal Year: 2009..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
- Improving Antimicrobial Prescribing Practices in the Neonatal Intensive Care UnitLisa Saiman; Fiscal Year: 2010..abstract_text> ..