Amar Sahay

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Adult hippocampal neurogenesis in depression
    Amar Sahay
    Department of Neuroscience, Division of Integrative Neuroscience, Columbia University, 1051 Riverside Drive, Box 87, PI Annex, Room 767B, New York, New York 10032, USA
    Nat Neurosci 10:1110-5. 2007
  2. ncbi Dentate gyrus neurogenesis and depression
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, NY 10032, USA
    Prog Brain Res 163:697-722. 2007
  3. ncbi Hippocampal neurogenesis and depression
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, NY 10032, USA
    Novartis Found Symp 289:152-60; discussion 160-4, 193-5. 2008
  4. ncbi Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, New York 10032, USA
    Nature 472:466-70. 2011
  5. ncbi Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis
    Kimberly N Scobie
    Department of Neuroscience and Psychiatry, Columbia University, New York, New York 10032, USA
    J Neurosci 29:9875-87. 2009
  6. ncbi Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders
    Mazen A Kheirbek
    Department of Neuroscience, Columbia University, New York, New York, USA
    Nat Neurosci 15:1613-20. 2012
  7. ncbi Pattern separation: a common function for new neurons in hippocampus and olfactory bulb
    Amar Sahay
    Departments of Neuroscience and Psychiatry, Columbia University, New York, USA
    Neuron 70:582-8. 2011
  8. ncbi Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events
    Amar Sahay
    Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 23:6671-80. 2003
  9. ncbi Secreted semaphorins modulate synaptic transmission in the adult hippocampus
    Amar Sahay
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 25:3613-20. 2005

Collaborators

Detail Information

Publications9

  1. ncbi Adult hippocampal neurogenesis in depression
    Amar Sahay
    Department of Neuroscience, Division of Integrative Neuroscience, Columbia University, 1051 Riverside Drive, Box 87, PI Annex, Room 767B, New York, New York 10032, USA
    Nat Neurosci 10:1110-5. 2007
    ..Finally, we speculate on how increased adult hippocampal neurogenesis may modulate dentate gyrus function to confer the behavioral effects of antidepressants...
  2. ncbi Dentate gyrus neurogenesis and depression
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, NY 10032, USA
    Prog Brain Res 163:697-722. 2007
    ..The implications of these findings are discussed to reevaluate the role of hippocampal neurogenesis in MDD...
  3. ncbi Hippocampal neurogenesis and depression
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, NY 10032, USA
    Novartis Found Symp 289:152-60; discussion 160-4, 193-5. 2008
    ..These findings suggest that the behavioural effects of chronic antidepressants require hippocampal neurogenesis and are mediated by an increased synaptic plasticity in the dentate gyrus...
  4. ncbi Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, New York 10032, USA
    Nature 472:466-70. 2011
    ....
  5. ncbi Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis
    Kimberly N Scobie
    Department of Neuroscience and Psychiatry, Columbia University, New York, New York 10032, USA
    J Neurosci 29:9875-87. 2009
    ..Klf-9-dependent neuronal maturation may therefore represent a candidate regulatory mechanism underlying these temporally distinct processes...
  6. ncbi Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders
    Mazen A Kheirbek
    Department of Neuroscience, Columbia University, New York, New York, USA
    Nat Neurosci 15:1613-20. 2012
    ..The development of new, pro-neurogenic compounds may therefore have therapeutic potential for patients who display pattern separation deficits...
  7. ncbi Pattern separation: a common function for new neurons in hippocampus and olfactory bulb
    Amar Sahay
    Departments of Neuroscience and Psychiatry, Columbia University, New York, USA
    Neuron 70:582-8. 2011
    ..See the related Perspective from Aimone, Deng, and Gage, "Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation," in this issue of Neuron...
  8. ncbi Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events
    Amar Sahay
    Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 23:6671-80. 2003
    ..Thus, our results show that Sema3F is the principal ligand for Npn-2-mediated axon guidance events in vivo and is a critical determinant of limbic and peripheral nervous system circuitry...
  9. ncbi Secreted semaphorins modulate synaptic transmission in the adult hippocampus
    Amar Sahay
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 25:3613-20. 2005
    ..These results suggest a novel role for semaphorins as synaptic modulators and illustrate the diverse repertoire of these guidance cues in both the formation and function of neural circuits...