Bret Rutherford

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint The role of patient expectancy in placebo and nocebo effects in antidepressant trials
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, Department of Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Box 98, New York, NY 10032
    J Clin Psychiatry 75:1040-6. 2014
  2. ncbi request reprint Clinic visits in late-life depression trials: effects on signal detection and therapeutic outcome
    Bret R Rutherford
    New York State Psychiatric Institute, New York, NY Columbia University College of Physicians and Surgeons, New York, NY Electronic address
    Am J Geriatr Psychiatry 22:1452-61. 2014
  3. pmc A model of placebo response in antidepressant clinical trials
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, USA
    Am J Psychiatry 170:723-33. 2013
  4. pmc Less is more in antidepressant clinical trials: a meta-analysis of the effect of visit frequency on treatment response and dropout
    Bret R Rutherford
    New York State Psychiatric Institute, 1051 Riverside Dr, Box 98, New York, NY 10032, USA
    J Clin Psychiatry 74:703-15. 2013
  5. pmc A randomized, prospective pilot study of patient expectancy and antidepressant outcome
    B R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    Psychol Med 43:975-82. 2013
  6. pmc Does differential drop-out explain the influence of study design on antidepressant response? A meta-analysis
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, United States
    J Affect Disord 140:57-65. 2012
  7. pmc Contribution of spontaneous improvement to placebo response in depression: a meta-analytic review
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 98, New York, NY 10032, USA
    J Psychiatr Res 46:697-702. 2012
  8. pmc Deconstructing pediatric depression trials: an analysis of the effects of expectancy and therapeutic contact
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 50:782-95. 2011
  9. pmc Antidepressant study design affects patient expectancy: a pilot study
    B Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 40:781-8. 2010
  10. pmc Study design affects participant expectations: a survey
    Bret R Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    J Clin Psychopharmacol 29:179-81. 2009

Detail Information

Publications16

  1. ncbi request reprint The role of patient expectancy in placebo and nocebo effects in antidepressant trials
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, Department of Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Box 98, New York, NY 10032
    J Clin Psychiatry 75:1040-6. 2014
    ..To determine whether patient expectancy plays a role in observed placebo and nocebo effects in 2 clinical trials...
  2. ncbi request reprint Clinic visits in late-life depression trials: effects on signal detection and therapeutic outcome
    Bret R Rutherford
    New York State Psychiatric Institute, New York, NY Columbia University College of Physicians and Surgeons, New York, NY Electronic address
    Am J Geriatr Psychiatry 22:1452-61. 2014
    ..This meta-analysis investigated how the supportive care provided in antidepressant clinical trials for late-life depression influences response and drop-out rates...
  3. pmc A model of placebo response in antidepressant clinical trials
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, USA
    Am J Psychiatry 170:723-33. 2013
    ....
  4. pmc Less is more in antidepressant clinical trials: a meta-analysis of the effect of visit frequency on treatment response and dropout
    Bret R Rutherford
    New York State Psychiatric Institute, 1051 Riverside Dr, Box 98, New York, NY 10032, USA
    J Clin Psychiatry 74:703-15. 2013
    ..We investigated how the number of follow-up visits affects response rates and dropout among patients in antidepressant trials for major depressive disorder (MDD)...
  5. pmc A randomized, prospective pilot study of patient expectancy and antidepressant outcome
    B R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    Psychol Med 43:975-82. 2013
    ..COMP conditions. We also tested the correlations between baseline expectancy score and final improvement in depressive symptoms across study groups...
  6. pmc Does differential drop-out explain the influence of study design on antidepressant response? A meta-analysis
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, United States
    J Affect Disord 140:57-65. 2012
    ..Increased patient expectancy in comparator trials has been hypothesized to explain this finding, but previous analyses have not accounted for the increased drop-out observed in placebo-controlled trials...
  7. pmc Contribution of spontaneous improvement to placebo response in depression: a meta-analytic review
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 98, New York, NY 10032, USA
    J Psychiatr Res 46:697-702. 2012
    ....
  8. pmc Deconstructing pediatric depression trials: an analysis of the effects of expectancy and therapeutic contact
    Bret R Rutherford
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 50:782-95. 2011
    ..This study investigated how study type, mean patient age, and amount of contact with research staff affected response rates to medication and placebo in acute antidepressant trials for pediatric depression...
  9. pmc Antidepressant study design affects patient expectancy: a pilot study
    B Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 40:781-8. 2010
    ....
  10. pmc Study design affects participant expectations: a survey
    Bret R Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    J Clin Psychopharmacol 29:179-81. 2009
    ..The goal of this survey was to determine whether respondents report higher expectations of improvement in comparator versus placebo-controlled clinical trials...
  11. pmc Does study design influence outcome?. The effects of placebo control and treatment duration in antidepressant trials
    Bret R Rutherford
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Psychother Psychosom 78:172-81. 2009
    ..This study investigated whether placebo control and treatment duration affect the outcome in antidepressant RCTs...
  12. ncbi request reprint Divergent fates of the medical humanities in psychiatry and internal medicine: should psychiatry be rehumanized?
    Bret R Rutherford
    Department of Psychiatry, NY State Psychiatric Institute, New York, NY 10032, USA
    Acad Psychiatry 32:206-13. 2008
    ....
  13. ncbi request reprint A survey of psychiatry residents' informed consent practices
    Bret R Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, USA
    J Clin Psychiatry 68:558-65. 2007
    ..A survey was used to investigate whether psychiatry residents obtained informed consent for treatment from 3 hypothetical patients...
  14. ncbi request reprint Do psychiatry residents obtain informed consent for psychotherapy?
    Bret R Rutherford
    Columbia University Center for Psychoanalytic Research and Training, USA
    J Am Psychoanal Assoc 54:1343-7. 2006
  15. ncbi request reprint An open trial of aripiprazole augmentation for SSRI non-remitters with late-life depression
    Bret Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    Int J Geriatr Psychiatry 22:986-91. 2007
    ..To evaluate the efficacy and tolerability of aripiprazole augmentation in elderly depressed patients who did not reach remission after treatment with an SSRI...
  16. ncbi request reprint Design makes a difference: a meta-analysis of antidepressant response rates in placebo-controlled versus comparator trials in late-life depression
    Joel R Sneed
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Geriatr Psychiatry 16:65-73. 2008
    ..No quantitative review has been conducted to test this hypothesis...