W Rosner

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. doi request reprint Interactions of sex hormone-binding globulin with target cells
    William Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center, College of, Physicians and Surgeons, Columbia University, New York, NY 10019, USA
    Mol Cell Endocrinol 316:79-85. 2010
  2. ncbi request reprint Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane
    W Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center and College of Physicians and Surgeons, Columbia University, New York, NY 10019, USA
    J Steroid Biochem Mol Biol 69:481-5. 1999
  3. ncbi request reprint Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement
    William Rosner
    St Luke s Roosevelt Hospital Center, 1000 Tenth Avenue, AJA 403, New York, New York 10019, USA
    J Clin Endocrinol Metab 92:405-13. 2007
  4. pmc Challenges to the measurement of estradiol: an endocrine society position statement
    William Rosner
    MD, St Luke s Roosevelt Hospital Center, Department of Medicine, Endocrinology, AJA 403, 1000 10th Avenue, New York, New York 10019
    J Clin Endocrinol Metab 98:1376-87. 2013
  5. pmc Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicing
    Atif M Nakhla
    Department of Urology, Columbia University, New York, NY 10032, USA
    BMC Mol Biol 10:37. 2009
  6. doi request reprint Toward excellence in testosterone testing: a consensus statement
    William Rosner
    St Luke s Roosevelt Hospital Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10019, USA
    J Clin Endocrinol Metab 95:4542-8. 2010
  7. ncbi request reprint Sex hormone-binding globulin is synthesized in target cells
    S M Kahn
    Department of Medicine, St Luke s Roosevelt Hospital Center, and College of Physicians and Surgeons, Columbia University, New York, New York 10019, USA
    J Endocrinol 175:113-20. 2002
  8. ncbi request reprint Proscar and propecia--a therapeutic perspective
    William Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center, 1000 Tenth Avenue, New York, NY 10019, USA
    J Clin Endocrinol Metab 89:3096-8. 2004
  9. ncbi request reprint Sex difference in the effect of obesity on 24-hour mean serum gonadotropin levels
    G W Strain
    Division of Endocrinology and Metabolism, Mount Sinai Medical Center, New York, USA
    Horm Metab Res 35:362-6. 2003
  10. ncbi request reprint Assays for testosterone in plasma: untested assays for an unproven syndrome
    W Rosner
    St Luke s Roosevelt Hospital and The College of Physicians and Surgeons, Columbia University, USA
    Ann Endocrinol (Paris) 64:115. 2003

Research Grants

  1. PROSTATIC STEROIDS AND SECOND MESSENGERS
    William Rosner; Fiscal Year: 2001
  2. Human Subjects Research Enhancements Programs
    William Rosner; Fiscal Year: 2002

Collaborators

Detail Information

Publications16

  1. doi request reprint Interactions of sex hormone-binding globulin with target cells
    William Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center, College of, Physicians and Surgeons, Columbia University, New York, NY 10019, USA
    Mol Cell Endocrinol 316:79-85. 2010
    ..Subsequently, it became clear that the cell membranes of selected tissues contained a receptor for SHBG (R(SHBG)). This review deals with what is known of that receptor - its anatomy, physiology and biochemistry...
  2. ncbi request reprint Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane
    W Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center and College of Physicians and Surgeons, Columbia University, New York, NY 10019, USA
    J Steroid Biochem Mol Biol 69:481-5. 1999
    ..These and other downstream effects of this system are reviewed...
  3. ncbi request reprint Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement
    William Rosner
    St Luke s Roosevelt Hospital Center, 1000 Tenth Avenue, AJA 403, New York, New York 10019, USA
    J Clin Endocrinol Metab 92:405-13. 2007
    ..The objective of the study was to evaluate the current state of clinical assays for total and free testosterone...
  4. pmc Challenges to the measurement of estradiol: an endocrine society position statement
    William Rosner
    MD, St Luke s Roosevelt Hospital Center, Department of Medicine, Endocrinology, AJA 403, 1000 10th Avenue, New York, New York 10019
    J Clin Endocrinol Metab 98:1376-87. 2013
    ..Such levels of estradiol are too low to be routinely measured accurately or precisely, and further evolution of analytical methods and the way in which estradiol is standardized is needed...
  5. pmc Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicing
    Atif M Nakhla
    Department of Urology, Columbia University, New York, NY 10032, USA
    BMC Mol Biol 10:37. 2009
    ..The SHBG gene was previously shown to express a second major transcript of unknown function, derived from an upstream promoter (P(T)), and two minor transcripts...
  6. doi request reprint Toward excellence in testosterone testing: a consensus statement
    William Rosner
    St Luke s Roosevelt Hospital Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10019, USA
    J Clin Endocrinol Metab 95:4542-8. 2010
    ..A group of concerned stakeholders was convened to address this problem...
  7. ncbi request reprint Sex hormone-binding globulin is synthesized in target cells
    S M Kahn
    Department of Medicine, St Luke s Roosevelt Hospital Center, and College of Physicians and Surgeons, Columbia University, New York, New York 10019, USA
    J Endocrinol 175:113-20. 2002
    ..We have reviewed the current state of knowledge on the SHBG gene and the role of SHBG in steroid signaling (we shall not address its function as a plasma-binding protein)...
  8. ncbi request reprint Proscar and propecia--a therapeutic perspective
    William Rosner
    Department of Medicine, St Luke s Roosevelt Hospital Center, 1000 Tenth Avenue, New York, NY 10019, USA
    J Clin Endocrinol Metab 89:3096-8. 2004
  9. ncbi request reprint Sex difference in the effect of obesity on 24-hour mean serum gonadotropin levels
    G W Strain
    Division of Endocrinology and Metabolism, Mount Sinai Medical Center, New York, USA
    Horm Metab Res 35:362-6. 2003
    ..Our results mandate that possible sex differences be investigated in all cases of dysregulation...
  10. ncbi request reprint Assays for testosterone in plasma: untested assays for an unproven syndrome
    W Rosner
    St Luke s Roosevelt Hospital and The College of Physicians and Surgeons, Columbia University, USA
    Ann Endocrinol (Paris) 64:115. 2003
  11. ncbi request reprint Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods
    Karen K Miller
    Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 89:525-33. 2004
    ..0001), but is a unitless number without reference to the physical reality of free T. We conclude that the mass action equation and equilibrium dialysis are the preferred methods for use in diagnosing androgen deficiency in women...
  12. doi request reprint Sex hormone-binding globulin influences gene expression of LNCaP and MCF-7 cells in response to androgen and estrogen treatment
    Scott M Kahn
    Columbia University Roosevelt Hospital, Department of Urology, New York, NY, USA
    Adv Exp Med Biol 617:557-64. 2008
    ....
  13. ncbi request reprint Sex hormone-binding globulin in the human prostate is locally synthesized and may act as an autocrine/paracrine effector
    Daniel J Hryb
    Department of Medicine, St Luke s Roosevelt Hospital Center, and College of Physicians and Surgeons, Columbia University, New York, New York 10019, USA
    J Biol Chem 277:26618-22. 2002
    ..These observations are consistent with the hypothesis that SHBG, destined to participate in signaling at the cell membrane, is locally regulated and produced...
  14. ncbi request reprint Sex steroids and the free hormone hypothesis
    William Rosner
    Cell 124:455-6; author reply 456-7. 2006
  15. ncbi request reprint Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response
    Margaret Wierman
    J Sex Med 4:1782-3; author reply 1784-5. 2007
  16. ncbi request reprint Androgen therapy in women: an Endocrine Society Clinical Practice guideline
    Margaret E Wierman
    University of Colorado at Denver and Health Sciences Center, Aurora, CO 80010, USA
    J Clin Endocrinol Metab 91:3697-710. 2006
    ..The objective was to provide guidelines for the therapeutic use of androgens in women...

Research Grants6

  1. PROSTATIC STEROIDS AND SECOND MESSENGERS
    William Rosner; Fiscal Year: 2001
    ....
  2. Human Subjects Research Enhancements Programs
    William Rosner; Fiscal Year: 2002
    ..All such monthly reviews and quizzes will be archived for review. All of the above activities will be designed to be continued after the completion of the initial year of support. ..