M Rosenbaum

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint School-based intervention acutely improves insulin sensitivity and decreases inflammatory markers and body fatness in junior high school students
    Michael Rosenbaum
    New York Presbyterian Hospital, New York, New York 10032, USA
    J Clin Endocrinol Metab 92:504-8. 2007
  2. ncbi request reprint Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
    Michael Rosenbaum
    Columbia University, New York, New York, USA
    J Clin Endocrinol Metab 87:2391-4. 2002
  3. pmc Racial/ethnic differences in clinical and biochemical type 2 diabetes mellitus risk factors in children
    Michael Rosenbaum
    Pediatrics Department, New York Presbyterian Hospital Columbia University Medical Center, New York, New York, USA
    Obesity (Silver Spring) 21:2081-90. 2013
  4. pmc Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome
    Nouhad Raissouni
    Division of Pediatric Endocrinology at Infants and Children s Hospital of Brooklyn at Maimonides and SUNY Downstate Medical Center, 1068 48th St, Brooklyn, NY, 11219, USA
    Int J Pediatr Endocrinol 2012:14. 2012
  5. doi request reprint Brain reorganization following weight loss
    Michael Rosenbaum
    Division of Molecular Genetics, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nestle Nutr Inst Workshop Ser 73:1-20. 2012
  6. ncbi request reprint Epidemiology of pediatric obesity
    Michael Rosenbaum
    New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Pediatr Ann 36:89-95. 2007
  7. pmc Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli
    Michael Rosenbaum
    Department of Pediatrics, Division of Molecular Genetics, Naomi Berrie Diabetes Center, Columbia University Medical Center New York Presbyterian Medical Center, New York, New York, USA
    J Clin Invest 118:2583-91. 2008
  8. ncbi request reprint Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight
    Michael Rosenbaum
    Columbia University College of Physicians and Surgeons, New York Presbyterian Medical Center, New York, NY 10032, USA
    Am J Clin Nutr 88:906-12. 2008
  9. pmc Energy intake in weight-reduced humans
    Michael Rosenbaum
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Brain Res 1350:95-102. 2010
  10. pmc Adaptive thermogenesis in humans
    M Rosenbaum
    Division of Molecular Genetics, Department of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Int J Obes (Lond) 34:S47-55. 2010

Collaborators

Detail Information

Publications24

  1. ncbi request reprint School-based intervention acutely improves insulin sensitivity and decreases inflammatory markers and body fatness in junior high school students
    Michael Rosenbaum
    New York Presbyterian Hospital, New York, New York 10032, USA
    J Clin Endocrinol Metab 92:504-8. 2007
    ..Risk factors for type 2 diabetes mellitus (T2DM) include obesity, family history, dyslipidemia, a proinflammatory state, impaired insulin secretory capacity, and insulin resistance...
  2. ncbi request reprint Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
    Michael Rosenbaum
    Columbia University, New York, New York, USA
    J Clin Endocrinol Metab 87:2391-4. 2002
    ..These data indicate that decrease leptin concentrations resulting from loss of fat mass account for some aspects of the endocrine/metabolic phenotype associated with the weight-reduced state...
  3. pmc Racial/ethnic differences in clinical and biochemical type 2 diabetes mellitus risk factors in children
    Michael Rosenbaum
    Pediatrics Department, New York Presbyterian Hospital Columbia University Medical Center, New York, New York, USA
    Obesity (Silver Spring) 21:2081-90. 2013
    ....
  4. pmc Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome
    Nouhad Raissouni
    Division of Pediatric Endocrinology at Infants and Children s Hospital of Brooklyn at Maimonides and SUNY Downstate Medical Center, 1068 48th St, Brooklyn, NY, 11219, USA
    Int J Pediatr Endocrinol 2012:14. 2012
    ..abstract:..
  5. doi request reprint Brain reorganization following weight loss
    Michael Rosenbaum
    Division of Molecular Genetics, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nestle Nutr Inst Workshop Ser 73:1-20. 2012
    ..Brain responses to food and the observed changes in energy expenditure that occur during maintenance of a reduced weight are largely reversed by the administration of the adipocyte-derived hormone, leptin. ...
  6. ncbi request reprint Epidemiology of pediatric obesity
    Michael Rosenbaum
    New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Pediatr Ann 36:89-95. 2007
  7. pmc Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli
    Michael Rosenbaum
    Department of Pediatrics, Division of Molecular Genetics, Naomi Berrie Diabetes Center, Columbia University Medical Center New York Presbyterian Medical Center, New York, New York, USA
    J Clin Invest 118:2583-91. 2008
    ..These data are consistent with a model of the weight-reduced state as one of relative leptin deficiency...
  8. ncbi request reprint Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight
    Michael Rosenbaum
    Columbia University College of Physicians and Surgeons, New York Presbyterian Medical Center, New York, NY 10032, USA
    Am J Clin Nutr 88:906-12. 2008
    ..An important clinical issue is whether this reduction, which predisposes to weight regain, persists over time...
  9. pmc Energy intake in weight-reduced humans
    Michael Rosenbaum
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Brain Res 1350:95-102. 2010
    ..Much of this biological opposition to sustained weight loss is mediated by the adipocyte-derived hormone "leptin."..
  10. pmc Adaptive thermogenesis in humans
    M Rosenbaum
    Division of Molecular Genetics, Department of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Int J Obes (Lond) 34:S47-55. 2010
    ..Important inferences can be drawn for therapeutic strategies by recognizing obesity as a disease in which the human body actively opposes the 'cure' over long periods of time beyond the initial resolution of symptomatology...
  11. pmc Effects of weight loss and leptin on skeletal muscle in human subjects
    Kenneth M Baldwin
    Department of Physiology and Biophysics, School of Medicine, University of California at Irvine, Irvine, California, USA
    Am J Physiol Regul Integr Comp Physiol 301:R1259-66. 2011
    ..These findings are consistent with the leptin-reversible increase in skeletal muscle chemomechanical work efficiency and decrease in the ratio of glycolytic/oxidative enzyme activities observed in subjects following dietary weight loss...
  12. pmc Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight
    Michael Rosenbaum
    Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Invest 115:3579-86. 2005
    ..These responses suggest that the weight-reduced state may be regarded as a condition of relative leptin insufficiency. Prevention of weight regain might be achievable by strategies relevant to reversing this leptin-insufficient state...
  13. ncbi request reprint beta-Cell function and insulin sensitivity in early adolescence: association with body fatness and family history of type 2 diabetes mellitus
    Michael Rosenbaum
    Department of Pediatrics, New York Presbyterian Medical Center, New York, New York 10032, USA
    J Clin Endocrinol Metab 89:5469-76. 2004
    ..These findings are consistent with a model for the physiology of T2DM in which a familial beta-cell dysfunction is unmasked by increasing insulin resistance secondary to overweight in this predominantly Latino population...
  14. ncbi request reprint Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function
    M Rosenbaum
    Rockefeller University, The Laboratory of Human Behavior and Metabolism, New York, NY, USA
    Am J Clin Nutr 71:1421-32. 2000
    ..Weight gain and loss increases and decreases energy expenditure, respectively, out of proportion to changes in metabolic mass...
  15. ncbi request reprint Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects
    Michael Rosenbaum
    Div of Molecular Genetics, Russ Berrie Medical Science Pavilion, 6th Fl, 1150 St Nicholas Ave, New York, NY 10032, USA
    Am J Physiol Regul Integr Comp Physiol 285:R183-92. 2003
    ..8 (20.5)%, P = 0.043]. Changes in muscle efficiency at altered body weight accounted for 35% of the change in daily energy expended in physical activity...
  16. ncbi request reprint Sexual dimorphism in circulating leptin concentrations is not accounted for by differences in adipose tissue distribution
    M Rosenbaum
    Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, USA
    Int J Obes Relat Metab Disord 25:1365-71. 2001
    ..Gender-related differences in the relative amounts of SAT and VAT may account for the greater circulating leptin concentration relative to fat-mass in females than males...
  17. ncbi request reprint Effects of weight change on plasma leptin concentrations and energy expenditure
    M Rosenbaum
    Laboratory of Human Behaviour and Metabolism, Rockefeller University, New York, New York 10021, USA
    J Clin Endocrinol Metab 82:3647-54. 1997
    ....
  18. pmc Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects
    Rochelle Goldsmith
    Department of Medicine, Division of Exercise Physiology, New York, New York, USA
    Am J Physiol Regul Integr Comp Physiol 298:R79-88. 2010
    ....
  19. ncbi request reprint Metabolic and hemodynamic responses to exercise in subcutaneous adipose tissue and skeletal muscle
    M Boschmann
    Laboratory of Human Behavior and Metabolism, The Rockefeller University, New York, USA
    Int J Sports Med 23:537-43. 2002
    ..It is concluded that lipids stored in muscle are rather used than lipids stored in adipose tissue for fueling the energy metabolism of muscle during exercise. During exercise, lipid mobilization is much greater in women than in men...
  20. pmc Effects of chronic weight perturbation on energy homeostasis and brain structure in mice
    Y Ravussin
    1Department of Pediatrics, Division of Molecular Genetics, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Physiol Regul Integr Comp Physiol 300:R1352-62. 2011
    ..The mouse model described here could help to identify the molecular/cellular mechanisms underlying both the defense mechanisms against sustained weight loss and the upward resetting of those mechanisms following sustained weight gain...
  21. ncbi request reprint Sexual dimorphism in the energy content of weight change
    A Pietrobelli
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University Institute of Human Nutrition, College of Physicians and Surgeons, New York, USA
    Int J Obes Relat Metab Disord 26:1339-48. 2002
    ..The energy content of weight change is assumed to be sex- and age-neutral at 3,500 kcal/pound or 32.2 MJ/kg...
  22. ncbi request reprint Diet composition and energy balance in humans
    J Hirsch
    Laboratory of Human Behavior and Metabolism, The Rockefeller University, New York, NY 10021 6399, USA
    Am J Clin Nutr 67:551S-555S. 1998
    ..The reverse occurred with a reduction in body weight. The set point at which energy storage is defended is clearly different in obese persons...
  23. doi request reprint Relationship between energy balance and complications after subarachnoid hemorrhage
    Neeraj Badjatia
    Departments of Neurology, Neurosurgery, and Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA
    JPEN J Parenter Enteral Nutr 34:64-9. 2010
    ..Subarachnoid hemorrhage patients are hypermetabolic and at risk for developing medical complications. A relationship was hypothesized between energy balance and complications following subarachnoid hemorrhage...
  24. pmc Obesity is associated with macrophage accumulation in adipose tissue
    Stuart P Weisberg
    Division of Moleuclar Genetics, Department of Pediatrics, Columbia University, New York, New York 10032, USA
    J Clin Invest 112:1796-808. 2003
    ..Adipose tissue macrophage numbers increase in obesity and participate in inflammatory pathways that are activated in adipose tissues of obese individuals...