STEVEN PAUL ROOSE

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Clinical trials in late-life depression: revisited
    Steven P Roose
    Department of Clinical Psychopharmacology, NY State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Geriatr Psychiatry 10:503-5. 2002
  2. ncbi request reprint Compliance: the impact of adverse events and tolerability on the physician's treatment decisions
    Steven P Roose
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Eur Neuropsychopharmacol 13:S85-92. 2003
  3. doi request reprint The development of a psychoanalytic outcome study: choices, conflicts, and consensus
    Steven P Roose
    Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Am Psychoanal Assoc 60:311-35. 2012
  4. ncbi request reprint Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease
    S P Roose
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    JAMA 279:287-91. 1998
  5. ncbi request reprint Pharmacologic treatment of depression in patients with heart disease
    Steven P Roose
    College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Psychosom Med 67:S54-7. 2005
  6. ncbi request reprint An open trial of venlafaxine for the treatment of late-life atypical depression
    Steven P Roose
    New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York 10032, USA
    Int J Geriatr Psychiatry 19:989-94. 2004
  7. ncbi request reprint Open-label study of mirtazapine orally disintegrating tablets in depressed patients in the nursing home
    Steven P Roose
    Columbia University College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Curr Med Res Opin 19:737-46. 2003
  8. ncbi request reprint The efficacy of antidepressants in the treatment of late-life depression
    Steven P Roose
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Psychopharmacol 25:S1-7. 2005
  9. ncbi request reprint Chairmen's introduction
    Steven P Roose
    Columbia University, New York State Psychiatric Institute, Unit 98, 1051 Riverside Drive, New York, NY 10032, USA
    Eur Neuropsychopharmacol 13:S67-8. 2003
  10. ncbi request reprint Depression: links with ischemic heart disease and erectile dysfunction
    Steven P Roose
    Department of Psychiatry, Columbia College of Physicians and Surgeons, New York, NY, USA
    J Clin Psychiatry 64:26-30. 2003

Research Grants

Detail Information

Publications49

  1. ncbi request reprint Clinical trials in late-life depression: revisited
    Steven P Roose
    Department of Clinical Psychopharmacology, NY State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Geriatr Psychiatry 10:503-5. 2002
  2. ncbi request reprint Compliance: the impact of adverse events and tolerability on the physician's treatment decisions
    Steven P Roose
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Eur Neuropsychopharmacol 13:S85-92. 2003
    ....
  3. doi request reprint The development of a psychoanalytic outcome study: choices, conflicts, and consensus
    Steven P Roose
    Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Am Psychoanal Assoc 60:311-35. 2012
    ....
  4. ncbi request reprint Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease
    S P Roose
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    JAMA 279:287-91. 1998
    ..Patients with heart disease need a safe and effective treatment for depression...
  5. ncbi request reprint Pharmacologic treatment of depression in patients with heart disease
    Steven P Roose
    College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Psychosom Med 67:S54-7. 2005
    ..Use of TCAs in patients with IHD carries a proven increased risk of cardiac morbidity and perhaps of mortality as well. The SSRI appear to be relatively safe and effective in the treatment for depression in patients with comorbid IHD...
  6. ncbi request reprint An open trial of venlafaxine for the treatment of late-life atypical depression
    Steven P Roose
    New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York 10032, USA
    Int J Geriatr Psychiatry 19:989-94. 2004
    ..This study reports the patient characteristics and treatment results of an eight-week open-label trial of venlafaxine in a sample of older depressed patients with atypical subtype...
  7. ncbi request reprint Open-label study of mirtazapine orally disintegrating tablets in depressed patients in the nursing home
    Steven P Roose
    Columbia University College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Curr Med Res Opin 19:737-46. 2003
    ..To evaluate the efficacy and tolerability of mirtazapine orally disintegrating tablets in depressed, elderly nursing home residents, under naturalistic study conditions...
  8. ncbi request reprint The efficacy of antidepressants in the treatment of late-life depression
    Steven P Roose
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Psychopharmacol 25:S1-7. 2005
    ..For future clinical trials to have maximal relevance, study design should evolve to reflect as closely as possible a typical clinical setting especially with respect to frequency and duration of patient visits...
  9. ncbi request reprint Chairmen's introduction
    Steven P Roose
    Columbia University, New York State Psychiatric Institute, Unit 98, 1051 Riverside Drive, New York, NY 10032, USA
    Eur Neuropsychopharmacol 13:S67-8. 2003
  10. ncbi request reprint Depression: links with ischemic heart disease and erectile dysfunction
    Steven P Roose
    Department of Psychiatry, Columbia College of Physicians and Surgeons, New York, NY, USA
    J Clin Psychiatry 64:26-30. 2003
    ....
  11. ncbi request reprint Antidepressant pharmacotherapy in the treatment of depression in the very old: a randomized, placebo-controlled trial
    Steven P Roose
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Psychiatry 161:2050-9. 2004
    ..This study determined the efficacy of antidepressant medication for the treatment of depression in the "old-old."..
  12. ncbi request reprint Treating depression in patients with ischaemic heart disease: which agents are best to use and to avoid?
    S P Roose
    College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Drug Saf 20:459-65. 1999
    ....
  13. ncbi request reprint Depression, anxiety, and the cardiovascular system: the psychiatrist's perspective
    S P Roose
    College of Physicians and Surgeons, Columbia University, New York, NY 10583, USA
    J Clin Psychiatry 62:19-22; discussion 23. 2001
    ....
  14. ncbi request reprint Treating sexual dysfunction: psychiatry's role in the age of sildenafil
    Steven P Roose
    Depression Research Unit, New York State Psychiatric Institute, New York, USA
    J Clin Psychiatry 63:3-4; discussion 23-5. 2002
  15. ncbi request reprint Low testosterone levels in elderly men with dysthymic disorder
    Stuart N Seidman
    Late Life Depression Clinic, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Psychiatry 159:456-9. 2002
    ..Symptoms of both HPG axis hypofunction and dysthymic disorder include dysphoria, fatigue, and low libido. The authors compared total testosterone levels in three groups of elderly men...
  16. ncbi request reprint Design makes a difference: a meta-analysis of antidepressant response rates in placebo-controlled versus comparator trials in late-life depression
    Joel R Sneed
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Geriatr Psychiatry 16:65-73. 2008
    ..No quantitative review has been conducted to test this hypothesis...
  17. ncbi request reprint Response inhibition predicts poor antidepressant treatment response in very old depressed patients
    Joel R Sneed
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Geriatr Psychiatry 15:553-63. 2007
    ..There have been mixed findings regarding the prognostic significance of age of onset, executive dysfunction, and hyperintensity burden on treatment outcome in late-life depression...
  18. ncbi request reprint Survey of psychiatric treatment among psychiatric residents in Manhattan: evidence of stigma
    Sylvia P Fogel
    Columbia University Center for Psychoanalytic Training and Research, Columbia University Department of Residency Training, New York State Psychiatric Institute, New York, USA
    J Clin Psychiatry 67:1591-8. 2006
    ..The purpose of this study was to determine the frequency and types of psychiatric treatment among residents and to assess residents' attitudes toward treatment...
  19. ncbi request reprint A survey of psychiatry residents' informed consent practices
    Bret R Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, USA
    J Clin Psychiatry 68:558-65. 2007
    ..A survey was used to investigate whether psychiatry residents obtained informed consent for treatment from 3 hypothetical patients...
  20. ncbi request reprint Do psychiatry residents obtain informed consent for psychotherapy?
    Bret R Rutherford
    Columbia University Center for Psychoanalytic Research and Training, USA
    J Am Psychoanal Assoc 54:1343-7. 2006
  21. pmc Randomized double-blind placebo-controlled donepezil augmentation in antidepressant-treated elderly patients with depression and cognitive impairment: a pilot study
    Gregory H Pelton
    Late Life Depression Clinic, The Memory Disorders Center, and The Division of Geriatric Psychiatry, New York State Psychiatric Institute, NY, USA
    Int J Geriatr Psychiatry 23:670-6. 2008
    ..To assess combined antidepressant and cognitive enhancer treatment in elderly patients presenting with depression plus cognitive impairment...
  22. pmc The vascular depression subtype: evidence of internal validity
    Joel R Sneed
    Department of Psychology, Queens College, City University of New York, Queens, New York 10032, USA
    Biol Psychiatry 64:491-7. 2008
    ..Vascular depression has been proposed as a unique diagnostic subtype in late life, yet no study has evaluated whether the specified clinical features associated with the illness are jointly indicative of an underlying diagnostic class...
  23. pmc Does study design influence outcome?. The effects of placebo control and treatment duration in antidepressant trials
    Bret R Rutherford
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Psychother Psychosom 78:172-81. 2009
    ..This study investigated whether placebo control and treatment duration affect the outcome in antidepressant RCTs...
  24. doi request reprint Effects of testosterone replacement in middle-aged men with dysthymia: a randomized, placebo-controlled clinical trial
    Stuart N Seidman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    J Clin Psychopharmacol 29:216-21. 2009
    ..8%) of 13 in the testosterone group and 1 (10%) of 10 in the placebo group (P = 0.03). Testosterone replacement may be an effective antidepressant strategy for late-onset male dysthymia...
  25. doi request reprint Study design affects participant expectations: a survey
    Bret R Rutherford
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    J Clin Psychopharmacol 29:179-81. 2009
    ..The goal of this survey was to determine whether respondents report higher expectations of improvement in comparator versus placebo-controlled clinical trials...
  26. doi request reprint Dropout rate of training cases: who and when
    Margaret Hamilton
    Columbia University College of Physicians and Surgeons, USA
    J Am Psychoanal Assoc 57:695-702. 2009
    ..This high dropout rate raises many questions about the reasons for it and suggests that there are critical educational issues regarding supervision and/or regarding candidates' technique during the induction phase...
  27. doi request reprint A prospective study of career development and analytic practice: the first five years
    Sabrina Cherry
    Columbia University College of Physicians and Surgeons, USA
    J Am Psychoanal Assoc 57:703-20. 2009
    ..These data are important for training programs, both in preparing their graduates for future practice and in supporting their postgraduate experience...
  28. doi request reprint A quality-based review of randomized controlled trials of psychodynamic psychotherapy
    Andrew J Gerber
    Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, New York, 10032, USA
    Am J Psychiatry 168:19-28. 2011
    ..The authors report results from application of the RCT-PQRS to 94 randomized controlled trials of psychodynamic psycho-therapy published between 1974 and May 2010...
  29. ncbi request reprint The specificity of neuropsychological impairment in predicting antidepressant non-response in the very old depressed
    Joel R Sneed
    Department of Psychiatry, Columbia State University, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Geriatr Psychiatry 23:319-23. 2008
    ..2007). The purpose of this study was to ascertain whether this effect is specific to response inhibition or whether impairment in other cognitive domains also predicts non-response...
  30. ncbi request reprint Talking about medication
    Robert Alan Glick
    Columbia University Center for Psychoanalytic Training and Research, USA
    J Am Psychoanal Assoc 54:745-62. 2006
    ..In these situations, effective analysis requires the analyst to be "bilingual," to hold in mind both the analytic and the pharmacological model...
  31. ncbi request reprint Vascular depression: A distinct diagnostic subtype?
    Joel R Sneed
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Biol Psychiatry 60:1295-8. 2006
    ..g., expert consensus), and vascular depression might serve as a prototype for future psychiatric classification...
  32. ncbi request reprint The sexual effects of testosterone replacement in depressed men: randomized, placebo-controlled clinical trial
    Stuart N Seidman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Sex Marital Ther 32:267-73. 2006
    ..Both T replacement and placebo were associated with improvement in sexual function and mood, but differences between T and placebo were not distinguishable...
  33. ncbi request reprint High-dose sildenafil citrate for selective serotonin reuptake inhibitor-associated ejaculatory delay: open clinical trial
    Stuart N Seidman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, and the New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 64:721-5. 2003
    ..Sildenafil citrate is effective for erectile dysfunction and appears to be safe at doses up to 200 mg...
  34. ncbi request reprint Sertraline treatment of elderly patients with depression and cognitive impairment
    D P Devanand
    Late Life Depression Clinic, Memory Disorders Center, Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 26, New York, NY 10032, USA
    Int J Geriatr Psychiatry 18:123-30. 2003
    ....
  35. ncbi request reprint Conducting analysis after September 11: implications for psychoanalytic technique
    Deborah L Cabaniss
    Columbia University Center for Psychoanalytic Training and Research, USA
    J Am Psychoanal Assoc 52:449-50. 2004
  36. ncbi request reprint The impact of graduation from analytic training
    Sabrina Cherry
    Columbia University Center for Psychoanalytic Training and Research, USA
    J Am Psychoanal Assoc 52:459-60. 2004
  37. ncbi request reprint Personal psychiatric treatment among psychiatric residents in Manhattan: evidence of stigma
    Sylvia Emmerich
    Columbia University Center for Psychoanalytic Training and Research, USA
    J Am Psychoanal Assoc 52:460-3. 2004
  38. ncbi request reprint The impact of graduation from psychoanalytic training
    Sabrina Cherry
    Columbia University College of Physicians and Surgeons, USA
    J Am Psychoanal Assoc 52:833-49. 2004
    ..For candidates, graduation profoundly impacts the structure of professional and personal life, but does not mean an end to learning...
  39. ncbi request reprint Psychoanalytic practice in the early postgraduate years
    Sabrina Cherry
    Columbia University College of Physicians and Surgeons, USA
    J Am Psychoanal Assoc 52:851-71. 2004
    ..Only one of the CA respondents met current APsaA immersion criteria for training analyst appointment...
  40. ncbi request reprint Candidate progression in analytic institutes: a multi-center study
    Deborah L Cabaniss
    Columbia University Center for Psychoanalytic Training and Research, Deborah L Cabaniss, 903 Park Avenue, NY, NY 10021 USA
    Int J Psychoanal 84:77-94. 2003
    ....
  41. ncbi request reprint Determining the duration of antidepressant treatment: application of signal detection methodology and the need for duration adaptive designs (DAD)
    Harold A Sackeim
    Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032, USA
    Biol Psychiatry 59:483-92. 2006
    ..With remission now the treatment goal, antidepressant trial duration has increased. However, most patients do not remit and are exposed to prolonged, ineffective treatment...
  42. ncbi request reprint Intramuscular testosterone supplementation to selective serotonin reuptake inhibitor in treatment-resistant depressed men: randomized placebo-controlled clinical trial
    Stuart N Seidman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    J Clin Psychopharmacol 25:584-8. 2005
    ..Treatment-resistant depression is a persistent clinical problem. Exogenous testosterone therapy has psychotropic effects and has been proposed as an antidepressant supplement, although this strategy has received limited systematic study...
  43. ncbi request reprint Optimal length of antidepressant trials in late-life depression
    Harold A Sackeim
    Department of Biological Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Psychopharmacol 25:S34-7. 2005
    ....
  44. ncbi request reprint Conducting analysis after September 11: implications for psychoanalytic technique
    Deborah L Cabaniss
    Columbia University College of Physicians and Surgeons, USA
    J Am Psychoanal Assoc 52:717-34. 2004
    ..These responses suggest that these analysts made decisions to alter their technique in certain ways in the wake of a catastrophic event shared by the community...
  45. ncbi request reprint Randomized, double-blind, placebo-controlled trial of fluoxetine treatment for elderly patients with dysthymic disorder
    D P Devanand
    Late Life Depression Clinic, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
    Am J Geriatr Psychiatry 13:59-68. 2005
    ..The authors compared the efficacy and side effects of fluoxetine and placebo in elderly outpatients with dysthymic disorder...
  46. ncbi request reprint An open treatment trial of venlafaxine for elderly patients with dysthymic disorder
    D P Devanand
    Late Life Depression Clinic and the Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
    J Geriatr Psychiatry Neurol 17:219-24. 2004
    ..These results indicate that in elderly patients with DD, placebo-controlled trials of a dual reuptake inhibitor such as venlafaxine would be needed to assess its efficacy or to compare its efficacy to that of other antidepressants...
  47. ncbi request reprint Treatment of depression in patients with heart disease
    Steven P Roose
    College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Biol Psychiatry 54:262-8. 2003
    ..Use of TCAs in patients with IHD carries a proven increased risk of cardiac morbidity and perhaps of mortality as well. The SSRIs appear to be relatively safe and effective treatment for depression in patients with comorbid IHD...
  48. ncbi request reprint Identifying and treating cognitive impairments in elderly patients
    Steven P Roose
    Department of Psychiatry, Columbia University, New York, NY, USA
    J Clin Psychiatry 68:e31. 2007
    ..This interactive Case and Comment follows Mr. P through the initial diagnosis and treatment of MCI and introduces measurements to predict his likelihood of converting to Alzheimer's disease...
  49. doi request reprint A new scale for assessing the quality of randomized clinical trials of psychotherapy
    James H Kocsis
    Weill Cornell Medical College, New York, NY 10065, USA
    Compr Psychiatry 51:319-24. 2010
    ..In 2004, the American Psychiatric Association's Committee on Research on Psychiatric Treatments appointed a subcommittee to investigate the status of empirical evidence with regard to psychodynamic psychotherapy...

Research Grants7

  1. ANTIDEPRESSANT TREATMENT OF MELANCHOLIA IN LATE LIFE
    Steven Roose; Fiscal Year: 2001
    ..Finally, The applicants expect HRQOL to show continued improvement during the continuation phase in euthymic patients and an advantage for the SSRI in HRQOL improvement due to a superior side effect profile. ..
  2. RESEARCH TRAINING IN GERIATRIC NEUROPSYCHIATRY
    Steven Roose; Fiscal Year: 2007
    ..This competing renewal strengthens the training program with greater emphasis on basic and translational research relevant to aging and late-life disorders. ..