Research Topics
Species | C ReitzSummaryAffiliation: Columbia University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Dyslipidemia and the risk of Alzheimer's diseaseChristiane Reitz
The Gertrude H Sergievsky, The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, and the Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Curr Atheroscler Rep 15:307. 2013..The aim of this article is to provide a comprehensive review of the findings of epidemiological, genetic, and cell biology studies aiming to elucidate the role of cholesterol in the pathogenesis of AD...- Effect of genetic variation in LRRTM3 on risk of Alzheimer diseaseChristiane Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, New York, USA
Arch Neurol 69:894-900. 2012..To explore the role of leucine-rich repeat transmembrane 3 (LRRTM3) in late-onset Alzheimer disease (AD) by independent genetic epidemiologic and functional studies... 
Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associationsChristiane Reitz
The Gertrude H Sergievsky Center, The Taub Institute for Research on Alzheimer s Disease and The Aging Brain New York, NY, USA
J Alzheimers Dis 30:S127-45. 2012..The aim of this review is to summarize the findings of epidemiological and cell biological studies to elucidate the role of cholesterol in AD etiology...- Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer diseaseChristiane Reitz
Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
Arch Neurol 67:1491-7. 2010..To reexamine the association of lipid levels with Alzheimer disease (AD) using Cox proportional hazards models... - A summary risk score for the prediction of Alzheimer disease in elderly personsChristiane Reitz
The Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
Arch Neurol 67:835-41. 2010..To develop a simple summary risk score for the prediction of Alzheimer disease in elderly persons based on their vascular risk profiles... - Linking hippocampal structure and function to memory performance in an aging populationChristiane Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Arch Neurol 66:1385-92. 2009..Magnetic resonance imaging is used to assess structure and function in the hippocampal formation... - Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and WhitesChristiane Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, New York 10032, USA
Arch Neurol 66:834-40. 2009..The validity of a self-reported stroke remains inconclusive... - Memory performance is related to amyloid and tau pathology in the hippocampusC Reitz
Gertrude H Sergievsky Center Taub Institute for Research on the Aging Brain, 630 West 168 Street, Columbia University, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 80:715-21. 2009..To determine the relation of amyloid and tau pathology in the hippocampal formation to decline in memory and other cognitive functions in Alzheimer's disease (AD)... - Relation between vascular risk factors and neuropsychological test performance among elderly persons with Alzheimer's diseaseChristiane Reitz
The Gertrude H Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Neurol Sci 257:194-201. 2007..Vascular risk factors increase the risk of Alzheimer's disease (AD). The mechanisms for these associations are unclear, and may be due to misdiagnosis of a vascular dementia syndrome as AD... - Effect of smoking and time on cognitive function in the elderly without dementiaChristiane Reitz
Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 65:870-5. 2005..Smoking does not affect cognitive performance in those persons aged <75 years... - Impact of plasma lipids and time on memory performance in healthy elderly without dementiaC Reitz
Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neurology 64:1378-83. 2005..CONCLUSIONS: Plasma lipid levels or treatment with lipid lowering agents in the elderly were not associated with changes in cognitive function... - Hypertension and the risk of mild cognitive impairmentChristiane Reitz
The Gertrude H Sergievsky Center, Columbia University Medical Center, Columbia University, New York, NY 10706, USA
Arch Neurol 64:1734-40. 2007..To explore whether hypertension is associated with the risk of mild cognitive impairment (MCI), an intermediate stage of dementia, because there are conflicting data relating hypertension to the risk of Alzheimer disease... - Subclinical cerebrovascular disease in mild cognitive impairmentJ A Luchsinger
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
Neurology 73:450-6. 2009..Cerebrovascular disease (CVD) may contribute to mild cognitive impairment (MCI). We sought to determine the relation of white matter hyperintensity (WMH) volume and infarcts in brain MRI to MCI in a community-based sample... - Stroke and memory performance in elderly persons without dementiaChristiane Reitz
Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, 630 W. 168th Street, New York, NY 10032, USA
Arch Neurol 63:571-6. 2006..CONCLUSION: A history of stroke is related to a progressive decline in memory and abstract/visuospatial performance, especially among men and those without an APOEepsilon4 allele... - Plasma homocysteine and risk of mild cognitive impairmentChristiane Reitz
The Gertrude H Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, N Y, USA
Dement Geriatr Cogn Disord 27:11-7. 2009..We sought to explore whether fasting plasma homocysteine is associated with the risk of mild cognitive impairment (MCI), an intermediate stage to dementia... - Endophenotypes in normal brain morphology and Alzheimer's disease: a reviewC Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Neuroscience 164:174-90. 2009..Given that the pathways from genotypes to end-stage phenotypes are circuitous at best, identifying endophenotypes more proximal to the effects of genetic variation may expedite the attempts to link genetic variants to disorders... - Aggregation of vascular risk factors and risk of incident Alzheimer diseaseJ A Luchsinger
Taub Institute for Research of Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
Neurology 65:545-51. 2005..The prevalence of Alzheimer disease (AD) is increasing in the elderly, and vascular risk factors may increase its risk... - Frequency of subclinical heart disease in elderly persons with dementiaChristiane Reitz
Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
Am J Geriatr Cardiol 16:183-8. 2007..With the increasing prevalence of Alzheimer's disease and vascular dementia, clinicians have to be more attentive to the presence of structural heart disease and its complications in persons with these conditions... - Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 1Richard Mayeux
Gertrude H Sergievsky Center, Columbia University, New York, NY, USA
Alzheimers Dement 7:15-34. 2011..Biomarkers for AD could also facilitate studies of the interactions of various forms of neurodegenerative disorders with cerebrovascular disease, resulting in "mixed dementia"... - Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern ManhattanAdam M Brickman
Departmentof Neurology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032
Arch Neurol 65:1053-61. 2008..Aging is accompanied by a decrease in brain volume and by an increase in cerebrovascular disease... - Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individualsJoseph H Lee
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, 630 W 168th St, New York, NY 10032, USA
Arch Neurol 68:320-8. 2011.... - Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohortAdam M Brickman
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Arch Neurol 67:564-9. 2010..Elevated blood pressure (BP) and fluctuation in BP may lead to cerebrovascular disease through ischemic changes and compromised cerebral autoregulation... - Plasma lipid levels in the elderly are not associated with the risk of mild cognitive impairmentChristiane Reitz
Gertrude H Sergievsky Center, Mailman School of Public Health, Columbia University College of Physicians and Surgeons, New York, N Y, USA
Dement Geriatr Cogn Disord 25:232-7. 2008..Baseline data were collected from 1992 to 1994, follow-up data were collected at 18-month intervals... - The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's diseaseJoseph H Lee
Sergievsky Center, 630 W 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 8:384-91. 2008..However, putative variants have not yet been identified. Further research is necessary to determine its utility as a diagnostic marker of AD or as a target for new therapeutic approaches... 
Relation of diabetes to mild cognitive impairmentJose A Luchsinger
Department of Medicine, Taub Institute for Research of Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY 10032, USA
Arch Neurol 64:570-5. 2007..Type 2 diabetes mellitus is an important risk factor for Alzheimer disease and is more prevalent in elderly minority persons compared with non-Hispanic white persons...- Comparison of clinical manifestations in Alzheimer disease and dementia with Lewy bodiesAngela Nervi
Gertrude H Sergievsky Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Columbia University, New York, NY 10032, USA
Arch Neurol 65:1634-9. 2008..The clinical delineation of dementia with Lewy bodies (DLB) from Alzheimer disease (AD) remains unclear... - Relation of plasma lipids to Alzheimer disease and vascular dementiaChristiane Reitz
Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
Arch Neurol 61:705-14. 2004..CONCLUSIONS: We found a weak relation between non-HDL-C, LDL-C, and HDL-C levels and the risk of VaD. Lipid levels and the use of agents to lower them do not seem to be associated with the risk of AD... - Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementiaChristiane Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J Alzheimers Dis 19:229-51. 2010..In addition, we discuss the potentials and difficulties researchers face in designing appropriate studies for gene discovery... - Use of genetic variation as biomarkers for Alzheimer's diseaseChristiane Reitz
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Ann N Y Acad Sci 1180:75-96. 2009..Here, we review the usefulness of genetic variation as diagnostic tools and biomarkers in LOAD and discuss the potentials and difficulties researchers face in designing appropriate studies for gene discovery...