Research Topics
| J G RabkinSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Treatment of HIV-related fatigue with armodafinil: a placebo-controlled randomized trialJudith G Rabkin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Psychosomatics 52:328-36. 2011..To evaluate the efficacy and safety of armodafinil in the treatment of fatigue in HIV+ patients, and to assess its effect on depressive symptoms and behavior once fatigue remitted...
Relationships among apathy, depression, and cognitive impairment in HIV/AIDSJ G Rabkin
Department of Psychiatry, Weill Medical College of Cornell University, New York, New York, USA
J Neuropsychiatry Clin Neurosci 12:451-7. 2000..Apathy was consistently related to depression and unrelated to neuropsychological impairment. Patient expectancies regarding medication adherence were unrelated to apathy when the analysis was controlled for depressive symptoms...
Predictors of employment of men with HIV/AIDS: a longitudinal studyJudith G Rabkin
Weill College of Medicine of Cornell University, New York, NY, USA
Psychosom Med 66:72-8. 2004..To identify patterns and predictors of work status and number of hours employed in a group of men with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)...
Mood and substance use disorders in older adults with HIV/AIDS: methodological issues and preliminary evidenceJudith G Rabkin
New York State Psychiatric Institute, and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
AIDS 18:S43-8. 2004..To review methodological issues and available data regarding the prevalence of psychiatric disorders in HIV-positive people over the age of 50 years...
How common is depression among ALS caregivers? A longitudinal studyJudith G Rabkin
Department of Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Amyotroph Lateral Scler 10:448-55. 2009..The high baseline rate of depression among caregivers of patients who planned tracheostomy decreased as caregivers instituted major changes in patient care or personal counseling...
Modafinil treatment for fatigue in HIV+ patients: a pilot studyJudith G Rabkin
New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 65:1688-95. 2004..The authors conducted a pilot study to evaluate the efficacy of modafinil for fatigue in this clinical population...
Prevalence of depressive disorders and change over time in late-stage ALSJ G Rabkin
New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
Neurology 65:62-7. 2005....
Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDSJudith G Rabkin
New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Am J Psychiatry 163:59-66. 2006..Subsyndromal major depressive disorder is common among HIV-positive adults. This study was designed to assess the efficacy of dehydroepiandrosterone (DHEA) as a potential treatment...
Predictors and course of elective long-term mechanical ventilation: A prospective study of ALS patientsJudith G Rabkin
Department of Psychiatry, Columbia University Medical Center, and New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Amyotroph Lateral Scler 7:86-95. 2006..ALS clinicians will need to recognize this motivation and provide appropriate clinical education to both patient and family...
Modafinil treatment of fatigue in patients with ALS: a placebo-controlled studyJudith G Rabkin
Department of Psychiatry, Columbia University, New York, New York, USA
Muscle Nerve 39:297-303. 2009..The number needed to treat was 1.6 (ITT). No medically serious adverse events were reported. Modafinil may be a promising intervention for fatigue in ALS patients. Replication in a larger study is needed...
HIV and depression: 2008 review and updateJudith G Rabkin
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 51, New York, NY 10032, USA
Curr HIV/AIDS Rep 5:163-71. 2008..Finally, the article summarizes international studies of depression prevalence in developing countries and the challenges regarding cross-national diagnostic definitions and measures...
Psychological effects of HAART: a 2-year studyJ G Rabkin
Department of Psychiatry, Weill College of Medicine, Cornell University, Ithaca, NY, USA
Psychosom Med 62:413-22. 2000....
Depression, distress and positive mood in late-stage cancer: a longitudinal studyJudith G Rabkin
Department of Psychiatry, Columbia University, New York, NY, USA
Psychooncology 18:79-86. 2009..To determine whether new-onset clinical depression emerges over time, and whether positive and negative mood levels change among patients with terminal cancer...
DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parametersJ G Rabkin
New York State Psychiatric Institute, NY 10032, USA
Psychoneuroendocrinology 25:53-68. 2000..A parallel group double blind clinical trial is indicated as the next step to more clearly identify therapeutic efficacy...
Modafinil and armodafinil treatment for fatigue for HIV-positive patients with and without chronic hepatitis CJ G Rabkin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Int J STD AIDS 22:95-101. 2011..Further investigation in a focused trial is warranted...
A double-blind, placebo-controlled trial of testosterone therapy for HIV-positive men with hypogonadal symptomsJ G Rabkin
New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York 10032, USA
Arch Gen Psychiatry 57:141-7; discussion 155-6. 2000..The goal was to evaluate the efficacy of testosterone in alleviation of hypogonadal symptoms (diminished libido, depressed mood, low energy, and depleted muscle mass) in men with symptomatic human immunodeficiency virus illness...
Modafinil treatment for fatigue in HIV/AIDS: a randomized placebo-controlled studyJudith G Rabkin
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, and New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 71:707-15. 2010..To evaluate the efficacy and safety of modafinil in the treatment of fatigue in patients with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) and to assess effect on depressive symptoms...
Testosterone therapy for human immunodeficiency virus-positive men with and without hypogonadismJ G Rabkin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York 10032, USA
J Clin Psychopharmacol 19:19-27. 1999..For patients with major depression and/or dysthymia, improvement was equal to that achieved with standard antidepressants...
Wish to die in end-stage ALSS M Albert
The Eleanor and Lou Gehrig MDA ALS Research Center, Department of Neurology, Columbia University, New York, NY 10032, USA
Neurology 65:68-74. 2005..In retrospective studies, estimates of hastened dying among seriously ill patients range from <2% in one national survey to as much as 20% in end-stage disease cohorts...
Disease severity, physical limitations and depression in HIV-infected menK W Griffin
HIV Center for Clinical and Behavioral Studies, New York, USA
J Psychosom Res 44:219-27. 1998..Findings suggest that physical limitations are more important than laboratory markers of disease progression in understanding psychological adjustment to illness in HIV-infected men...
Stability and change in personality disorder symptomatology: findings from a longitudinal study of HIV+ and HIV- menJ G Johnson
Department of Psychiatry, Columbia University, New York, New York, USA
J Abnorm Psychol 106:154-8. 1997....
Fluoxetine treatment for depression in patients with HIV and AIDS: a randomized, placebo-controlled trialJ G Rabkin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York 10032, USA
Am J Psychiatry 156:101-7. 1999....
Resilience and distress among amyotrophic lateral sclerosis patients and caregiversJ G Rabkin
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Psychosom Med 62:271-9. 2000....
Prevalence of fatigue and depression in ALS patients and change over timeM C McElhiney
New York State Psychiatric Institute, Unit 51, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 80:1146-9. 2009..Amyotrophic lateral sclerosis (ALS) patients report both fatigue and depression. It is not clear how frequently each occurs, to what extent they occur together, how each relates to ALS disease status, or their stability over time...
Antidepressant treatment of depression in HIV-seropositive womenS J Ferrando
Department of Psychiatry, Weill Medical College of Cornell University, New York, NY, USA
J Clin Psychiatry 60:741-6. 1999..This study aimed to assess the effectiveness of fluoxetine and sertraline in treating depressed women who are seropositive for the human immunodeficiency virus (HIV) and to document barriers to study participation...
Hopelessness as a mediator of the association between social support and depressive symptoms: findings of a study of men with HIVJ G Johnson
Biometrics Research Unit, New York State Psychiatric Institute, Columbia University, New York, 10032, USA
J Consult Clin Psychol 69:1056-60. 2001..Increases in hopelessness predicted increases in depression after controlling for baseline social support. Low baseline social support did not predict increased depression when hopelessness was controlled statistically...
The relationship between employment and neuropsychological impairment in HIV infectionW G van Gorp
Weill Medical College, Cornell University, New York, NY 10021, USA
J Int Neuropsychol Soc 5:534-9. 1999..The results are discussed within the context of similar findings in other illnesses...
Development of the Impact of Weight Loss Scale (IWLS): a psychometric study in a sample of men with HIV/AIDSG J Wagner
Department of Psychiatry, New York State Psychiatric Institute, NY 10032, USA
AIDS Care 11:453-7. 1999..28; amount of weight loss, r = 0.30). The IWLS is a brief self-report measure with good psychometric characteristics and has potential utility in both research and clinical applications...
Health locus of control, distress, and utilization of protease inhibitors among HIV-positive menS Evans
Department of Psychiatry, Weill Medical College of Cornell University, New York, NY 10021, USA
J Psychosom Res 49:157-62. 2000..To investigate the relationship between health locus of control (HLOC), distress, and protease inhibitor (PI) utilization in gay/bisexual men in all stages of HIV illness...
Longitudinal improvement in psychomotor processing speed is associated with potent combination antiretroviral therapy in HIV-1 infectionStephen J Ferrando
Department of Psychiatry, Weill Medical College of Cornell University, USA
J Neuropsychiatry Clin Neurosci 15:208-14. 2003..This study contributes to the growing literature documenting the longitudinal benefit provided by potent antiretroviral therapy for neuropsychological function, particularly psychomotor processing speed, in patients with HIV illness...
Antidepressant specificity in atypical depressionM R Liebowitz
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY
Arch Gen Psychiatry 45:129-37. 1988..This is consonant with some but not other recent findings and requires replication. Overall, the concept of atypical depression as a subtype that is preferentially responsive to monoamine oxidase inhibitors is supported...
Sexual risk behavior changes among HIV+ and HIV-female injecting drug users over 4 yearsC Dolezal
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, NY 10032, USA
Women Health 27:1-17. 1998....
A prospective cohort study of neuropsychological test performance in ALSPaul H Gordon
Department of Neurology, Columbia University, New York, NY, USA
Amyotroph Lateral Scler 11:312-20. 2010..The strongest neuropsychological predictors of cognitive status were measures of executive, episodic memory and language function. Cognitively impaired patients had shorter survival time...
Testosterone versus fluoxetine for depression and fatigue in HIV/AIDS: a placebo-controlled trialJudith G Rabkin
New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychopharmacol 24:379-85. 2004..Accordingly, this double-blind trial was designed to determine whether testosterone, as well as fluoxetine, is superior to placebo for depression, fatigue, or both...
Increase in body cell mass and decrease in wasting are associated with increasing potency of antiretroviral therapy for HIV infectionStephen J Ferrando
Department of Psychiatry, Weill Medical College of Cornell University, New York, New York, USA
AIDS Patient Care STDS 19:216-23. 2005....
Neuropsychiatric predictors of return to work in HIV/AIDSWilfred G van Gorp
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
J Int Neuropsychol Soc 13:80-9. 2007..These findings indicate that memory is a key neuropsychiatric variable that is perhaps most relevant to HIV+ persons' quest to return to work...
Provigil (modafinil) plus cognitive behavioral therapy for methamphetamine use in HIV+ gay men: a pilot studyMartin C McElhiney
Therapeutics, New York State Psychiatric Institute, New York, New York, USA
Am J Drug Alcohol Abuse 35:34-7. 2009..To evaluate the efficacy of modafinil combined with cognitive behavioral therapy (CBT) for treatment of methamphetamine (MA) dependence among HIV+ gay men...
Difficulties in interpersonal relationships associated with personality disorders and axis I disorders: a community-based longitudinal investigationJ G Johnson
Columbia University, NY, USA
J Pers Disord 14:42-56. 2000..The present findings are of particular interest because they suggest that PDs are associated with loneliness, social conflict, and a lack of social support among men in the community, whether or not Axis I disorders are present...
Palliative care for patients with amyotrophic lateral sclerosis: "prepare for the worst and hope for the best"Hiroshi Mitsumoto
Eleanor and Lou Gehrig ALS MDA Center, College of Physicians and Surgeons, Columbia University, Neurological Institute, New York, NY 10032, USA
JAMA 298:207-16. 2007....
Depression and distress in older HIV+ adultsJudith G Rabkin
GMHC Treat Issues 21:3-5. 2007
Research Grants
- Modafinil Treatment for Fatigue in HIV+ PatientsJudith Rabkin; Fiscal Year: 2007..The major aims concern modafinil efficacy for fatigue compared to placebo, safety in terms of effects on immunologic/virologic measures, and impact on depressive symptoms when present at baseline. ..
- DYING AT HOME OF AIDS & CANCER: PREFERENCES & OUTCOMESJudith Rabkin; Fiscal Year: 2004..The data collected in the preliminary study will be used in the full-scale study. ..
- DHEA EFFECTS ON MOOD IN DEPRESSED HIV+ PATIENTSJudith Rabkin; Fiscal Year: 2003..This will permit the investigators to assess potential underlying mechanisms for the putative therapeutic effects of DHEA on mood, libido, and body composition. ..
