Research Topics
| D S PineSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Memory and anxiety in prepubertal boys at risk for delinquencyD S Pine
Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, NY 10032, USA
J Am Acad Child Adolesc Psychiatry 38:1024-31. 1999..To examine the association between memory and anxiety symptoms in young urban-dwelling boys...- The association between childhood depression and adulthood body mass indexD S Pine
Division of Child Psychiatry, New York State Psychiatric Institute and Columbia University, New York, New York 10032, USA
Pediatrics 107:1049-56. 2001..However, there are limited data on the association between major depression in childhood and BMI in adulthood. The current study examines this association... - Differential carbon dioxide sensitivity in childhood anxiety disorders and nonill comparison groupD S Pine
New York State Psychiatric Institute, Box 74, 1051 Riverside Dr, New York, NY 10032, USA
Arch Gen Psychiatry 57:960-7. 2000.... - Social phobia and the persistence of conduct problemsD S Pine
New York State Psychiatric Institute and Columbia University, New York, USA
J Child Psychol Psychiatry 41:657-65. 2000..Various cognitive or biological factors might account for these moderating effects on conduct problems... - Cerebral laterality in adolescent major depressionD S Pine
Division of Child Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 74, New York, NY 10032 3784, USA
Psychiatry Res 93:135-44. 2000..Further studies using longitudinal and family-based designs, as well as various measures of regional brain activity, are needed to enhance understanding of associations between cerebral laterality and psychopathology across development... - Electroencephalographic asymmetries in adolescents with major depression: influence of comorbidity with anxiety disordersL M Kentgen
Department of Child Psychiatry, Unit 74, New York State Psychiatric Institute, 1051 Riverside Drive, New York, New York 10032 3784, USA
J Abnorm Psychol 109:797-802. 2000..These preliminary findings are similar to those from adult studies that suggest that MDD is associated with right parietotemporal hypoactivation... - Dichotic listening deficits and the prediction of substance use in young boysG A Wasserman
Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, NY 10032, USA
J Am Acad Child Adolesc Psychiatry 38:1032-9. 1999..The current study examines the relationship between verbal deficits, assessed through a dichotic listening test, and children's substance use... - Association between cigarette smoking and anxiety disorders during adolescence and early adulthoodJ G Johnson
Box 60, New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
JAMA 284:2348-51. 2000..Cigarette smoking is associated with some anxiety disorders, but the direction of the association between smoking and specific anxiety disorders has not been determined... - Enhanced stress reactivity in paediatric anxiety disorders: implications for future cardiovascular healthC Monk
Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, NY 10032, USA
Int J Neuropsychopharmacol 4:199-206. 2001..As such, the current data suggest that the presence of an anxiety disorder may identify youth who exhibit autonomic profiles that place them at risk for cardiac disease... - Changes in autonomic regulation with age: implications for psychopharmacologic treatments in children and adolescentsC A Galanter
New York State Psychiatric Institute and Columbia University, New York, USA
J Child Adolesc Psychopharmacol 9:257-65. 1999..Parasympathetic changes, as reflected by HPV, do not. In light of these findings, more research is needed on children's and adolescents' relative cardiac risk with psychotropic medications as opposed to adults'... - Longitudinal relationships between childhood, adolescent, and adult eating disordersL A Kotler
Department of Child Psychiatry, Columbia University, College of Physicians and Surgeons New York State Psychiatric Institute, New York, USA
J Am Acad Child Adolesc Psychiatry 40:1434-40. 2001..questions are answered: (1) How stable are eating disorder symptoms and diagnoses over a 17-year interval from childhood to adulthood? (2) Do early childhood eating problems predict the occurrence of eating disorders in adulthood?.. - Contribution of maternal smoking during pregnancy and lead exposure to early child behavior problemsG A Wasserman
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Neurotoxicol Teratol 23:13-21. 2001..Because the present smoking/child behavior associations persist after control for individual and social factors also related to behavior problems, possible biological mediators are considered... - Attention bias to threat in maltreated children: implications for vulnerability to stress-related psychopathologyDaniel S Pine
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramurral Research Program, Bethesda, MD 20817 2670, USA
Am J Psychiatry 162:291-6. 2005..They tested the hypothesis that attention bias to threatening facial photographs is associated with maltreatment and PTSD... - Autism spectrum traits in children with mood and anxiety disordersKenneth E Towbin
Mood and Anxiety Program, National Institute of Mental Health, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Child Adolesc Psychopharmacol 15:452-64. 2005..These results demonstrate a need to develop valid and reliable instruments to screen for ASDs in children presenting outside of ASD clinics... - Deficits in social cognition and response flexibility in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, NIMH, 15K North Dr, Room 102, MSC 2670, Bethesda, MD 20892, USA
Am J Psychiatry 162:1644-51. 2005..The purpose of this study was to test the hypothesis that youths with bipolar disorder would perform more poorly than matched healthy comparison subjects on measures of social cognition, motor inhibition, and response flexibility... - Comorbid anxiety in phenotypes of pediatric bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorders Program, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
J Child Adolesc Psychopharmacol 15:534-48. 2005..Adult BPD studies suggest comorbid anxiety disorders are common and impact treatment outcome. We explored the association of comorbid anxiety with two phenotypes of pediatric BPD... - Editorial: Answering questions in developmental science: separating the wheat from the chaffDaniel S Pine
J Child Psychol Psychiatry 48:1157-9. 2007 - Does major depressive disorder in parents predict specific fears and phobias in offspring?Matthew G Biel
Department of Child and Adolescent Psychiatry, NYU Child Study Center, NYU School of Medicine, New York University, New York, USA
Depress Anxiety 25:379-82. 2008..Elevated rates of specific fears in offspring of parents with MDD+anxiety disorder may be a function of more severe parental psychopathology, increased genetic loading, or unmeasured environmental influences... - Memory deficits in children with and at risk for anxiety disordersRoma A Vasa
Johns Hopkins University School of Medicine, Baltimore, Maryland 21211, USA
Depress Anxiety 24:85-94. 2007..These findings are relevant to understanding the phenomenology of childhood anxiety disorders and may provide insights into the neural circuits underlying these disorders... - Behavioral alterations in reward system function: the role of childhood maltreatment and psychopathologyAmanda E Guyer
Mood and Anxiety Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 45:1059-67. 2006..To examine in children the influence of maltreatment and associated psychiatric sequelae on behavioral responses to reward stimuli... - Chronic versus episodic irritability in youth: a community-based, longitudinal study of clinical and diagnostic associationsEllen Leibenluft
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
J Child Adolesc Psychopharmacol 16:456-66. 2006..In psychiatric nosology, a distinction is made between chronic and episodic irritability. This study examines the validity of this distinction... - Specificity of facial expression labeling deficits in childhood psychopathologyAmanda E Guyer
Mood and Anxiety Program MAP, National Institute of Mental Health NIMH, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
J Child Psychol Psychiatry 48:863-71. 2007..We examined whether face-emotion labeling deficits are illness-specific or an epiphenomenon of generalized impairment in pediatric psychiatric disorders involving mood and behavioral dysregulation... - Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulationMelissa A Brotman
Emotion and Development Branch and the Genetic Basis of Mood and Anxiety Disorders Unit, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Psychiatry 164:1238-41. 2007..The authors compared axis I diagnoses in parents of children with narrow phenotype bipolar disorder and parents of youth with severe mood dysregulation... - Association between lung function and mental health problems among adults in the United States: findings from the First National Health and Nutrition Examination SurveyRenee D Goodwin
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Epidemiol 165:383-8. 2007..Future studies are needed to determine the mechanisms of these associations... - Performance on a virtual reality spatial memory navigation task in depressed patientsNeda F Gould
Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, NIMH, Mark O Hatfield Clinical Research Center, 10 Center Dr, Bethesda, MD 20892, USA
Am J Psychiatry 164:516-9. 2007..Findings on spatial memory in depression have been inconsistent. A navigation task based on virtual reality may provide a more sensitive and consistent measure of the hippocampal-related spatial memory deficits associated with depression... - Cognitive flexibility in phenotypes of pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 9000 Rockville Pike, MSC 2670 Building 15K Room 204, Bethesda MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 46:341-55. 2007..6 +/- 2.4 years). Cognitive flexibility is relevant to symptoms of BD involving dysfunctional reward systems (e.g., excessive goal-directed activity and pleasure-seeking in mania; anhedonia in depression)... - Response to 5% carbon dioxide in children and adolescents: relationship to panic disorder in parents and anxiety disorders in subjectsDaniel S Pine
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, MD 20817, USA
Arch Gen Psychiatry 62:73-80. 2005..Exaggerated responses to CO(2) inhalation have been reported in adults with PD and their unaffected adult relatives, as well as in clinic-referred children with anxiety disorders... 
Agoraphobia and panic. Prospective-longitudinal relations suggest a rethinking of diagnostic conceptsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychother Psychosom 77:147-57. 2008..The aim of the current study is to prospectively examine the 10-year natural course of PA, PD and AG in the first three decades of life, their stability and their reciprocal transitions...- Face-emotion processing in offspring at risk for panic disorderDaniel S Pine
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, MD 20817 2670, USA
J Am Acad Child Adolesc Psychiatry 44:664-72. 2005..This study tested the hypotheses that offspring of parents with PD and offspring with anxiety disorders display relatively greater sensitivity and attention allocation to fear provocation... 
Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disordersKarina Blair
Mood and Anxiety Program, NIMH, NIH, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
Am J Psychiatry 165:1193-202. 2008..Functional magnetic resonance imaging assessed the neural response to facial expressions in generalized social phobia and generalized anxiety disorder...- Lung disease and internalizing disorders. Is childhood abuse a shared etiologic factor?Renee D Goodwin
Columbia University, New York, NY 10032, USA
J Psychosom Res 55:215-9. 2003..To investigate the role of childhood abuse in the relationship between panic attack, depression and lung disease among adults in the population... - Neurological soft signs and disruptive behavior among children of opiate dependent parentsJeffrey J Wilson
Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Child Psychiatry Hum Dev 34:19-34. 2003.... - Consequences and correlates of adolescent depressionSherry Glied
Department of Health Policy and Management, Mailman School of Public Health, Columbia University, New York, NY, USA
Arch Pediatr Adolesc Med 156:1009-14. 2002..02; P<.001), and suicidal ideation (odds ratio, 16.59; P<.001). CONCLUSION: High levels of depressive symptoms are correlated with serious and significant consequences, even after controlling for life circumstances... - Asthma and panic attacks among youth in the communityRenee D Goodwin
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Asthma 40:139-45. 2003..To determine the association between asthma and panic attacks among youth in the community... - Respiratory disease and panic attacks among adults in the United StatesRenee D Goodwin
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
Chest 122:645-50. 2002..To determine the association between respiratory disease and panic attacks among adults in the US population... - Clinical correlates of episodicity in juvenile maniaRobinder K Bhangoo
The Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
J Child Adolesc Psychopharmacol 13:507-14. 2003..The latter hypothesis should be tested in a sample where relatives are interviewed directly... - Relationship between separation anxiety disorder, parental panic disorder, and atopic disorders in children: a controlled high-risk studyMarcia J Slattery
Mayo Clinic, Rochester, MN 55905, USA
J Am Acad Child Adolesc Psychiatry 41:947-54. 2002..Results do not appear to support that having both childhood SAD and a parent with PD confers increased risk for atopic disorders above and beyond either condition alone... - Generalizability and correlates of clinically derived panic subtypes in the populationRenee D Goodwin
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
Depress Anxiety 15:69-74. 2002..Observed differences between these subtypes may influence results from clinical samples... - Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorderChristian Grillon
NIMH MAP, 15K North Dr, Bldg 15k, Rm 113, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 165:898-904. 2008..The authors tested the hypothesis that elevated anxious reactivity, specifically toward unpredictable aversive events, is a psychophysiological correlate of panic disorder... - Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disordersMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Biol Psychiatry 61:819-21. 2007..Although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness... - A functional magnetic resonance imaging investigation of uncertainty in adolescents with anxiety disordersAmy L Krain
New York University Child Study Center, New York University School of Medicine, New York, NY 10016, USA
Biol Psychiatry 63:563-8. 2008..As such, the present study examines the relationship between IU and neural responses to uncertainty in anxious adolescents... - Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of lifeKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Arch Gen Psychiatry 64:903-12. 2007.... - Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorderChristopher S Monk
Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109 1043, USA
Arch Gen Psychiatry 65:568-76. 2008..Disturbed interactions between these structures may underlie pediatric anxiety. To date, no study has selectively examined responses to briefly presented threats in GAD or in pediatric anxiety... - Facial emotion labeling deficits in children and adolescents at risk for bipolar disorderMelissa A Brotman
Mood and Anxiety Disorders Program, NIMH, NIH, Bethesda, MD 20892, USA
Am J Psychiatry 165:385-9. 2008.... - Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigmJennifer Y F Lau
Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, 15K North Drive, MSC 2670, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 47:94-102. 2008..Adult data suggest that anxiety disorders involve elevated fear but intact differential conditioning. We used a novel paradigm to assess fear conditioning in pediatric anxiety patients... - Elucidating risk mechanisms of gene-environment interactions on pediatric anxiety: integrating findings from neuroscienceJennifer Y F Lau
Mood and Anxiety Program, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
Eur Arch Psychiatry Clin Neurosci 258:97-106. 2008..Exploring these relationships during development is crucial, given that these early life processes may potentially shape longer-term patterns of emotional behavior, and therefore life-long trajectories of anxiety... - Autism spectrum disorder scale scores in pediatric mood and anxiety disordersDaniel S Pine
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K North Drive, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 47:652-61. 2008..To compare scores on autism spectrum disorder (ASD) symptom scales in healthy youths and youths with mood or anxiety disorders... - Processing of differentially valued rewards and punishments in youths with bipolar disorder or severe mood dysregulationGeoff Rau
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1289, USA
J Child Adolesc Psychopharmacol 18:185-96. 2008..Therefore, we hypothesized that SMD, but not BD, youths would be impaired on a decision-making task that has identified reward- and punishment-processing deficits in individuals with psychopathy... - Recognition of facial emotions among maltreated children with high rates of post-traumatic stress disorderCarrie L Masten
Department of Psychology, University of California, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095, USA
Child Abuse Negl 32:139-53. 2008..However, research has provided little evidence indicating how high rates of PTSD might relate to maltreated children's processing of emotions... - Elevated fear conditioning to socially relevant unconditioned stimuli in social anxiety disorderShmuel Lissek
NIMH, NIH, 15K North Dr, Rm 200, Bethesda, MD 20892 2670, USA
Am J Psychiatry 165:124-32. 2008..This study represents the first effort to assess the conditioning correlates of social anxiety disorder within an ecologically enhanced paradigm... - Assessing gene-environment interactions on anxiety symptom subtypes across childhood and adolescenceJennifer Y F Lau
US National Institute of Mental Health, 15K, North Drive, Bethesda, MD 20892 2670, USA
Dev Psychopathol 19:1129-46. 2007..We interpret these preliminary findings tentatively in the context of gene-environment interaction on anxiety in general, and on early separation and later panic anxiety in particular... - Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxietyAmanda E Guyer
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Dr, Room 208, Bethesda, MD 20892 2670, USA
Arch Gen Psychiatry 65:1303-12. 2008..Such fear-circuitry dysfunction may also manifest when anticipated social evaluation leads socially anxious adolescents to misperceive peers as threatening... - Different psychophysiological and behavioral responses elicited by frustration in pediatric bipolar disorder and severe mood dysregulationBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Section on Development and Affective Neuroscience, NIMH Mood and Anxiety Program, Bethesda, MD 20892, USA
Am J Psychiatry 164:309-17. 2007..e., a history of at least one manic or hypomanic episode with euphoric mood) as well as those with no diagnosis (i.e., healthy comparison children)... - Classical fear conditioning in the anxiety disorders: a meta-analysisShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Behav Res Ther 43:1391-424. 2005.... - Memory and learning in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 44:461-9. 2005..To test the hypothesis that patients with pediatric bipolar disorder (PBPD) would demonstrate impairment relative to diagnosis-free controls of comparable age, gender, and IQ on measures of memory functioning... - Face-memory and emotion: associations with major depression in children and adolescentsDaniel S Pine
Section on Development and Affective Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, Bethesda, Maryland, USA
J Child Psychol Psychiatry 45:1199-208. 2004..The study also examines the relationship between parental MDD and memory performance in offspring... - A neuroimaging method for the study of threat in adolescentsChristopher S Monk
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Dev Psychobiol 43:359-66. 2003..Those who reported increased fear showed right amygdala activation during the threat condition and left amygdala activation in the safe condition. These procedures offer a promising tool for studying youth with anxiety disorders... - Irritability in pediatric mania and other childhood psychopathologyEllen Leibenluft
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health DHHS, 10 Center Drive, Room 4N 208, MSC 1255, Bethesda, MD 20892, USA
Ann N Y Acad Sci 1008:201-18. 2003..Examples of such paradigms are described, and the pharmacology of irritability is reviewed briefly... - Neuropsychological performance in pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health Mood and Anxiety Disorders Program, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-1255, USA
Biol Psychiatry 55:32-9. 2004..Our work suggests altered ventrolateral prefrontal cortex function, especially when linked to other lesion and neuroimaging studies... - Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in children and adolescentsJoseph T Coyle
J Am Acad Child Adolesc Psychiatry 42:1494-503. 2003..National efforts are required to restructure healthcare delivery and provider training and to immediately develop more advanced research on pathophysiology, prevention, and services delivery effectiveness... - Facial expression recognition in adolescents with mood and anxiety disordersErin B McClure
National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 2670, USA
Am J Psychiatry 160:1172-4. 2003..The authors examined facial expression recognition in adolescents with mood and anxiety disorders... - Treating children and adolescents with selective serotonin reuptake inhibitors: how long is appropriate?Daniel S Pine
National Institute of Mental Health, Intramural Research Program, Bethesda, Maryland 20892 1381, USA
J Child Adolesc Psychopharmacol 12:189-203. 2002..Third, SSRI treatment should be reinitiated in children who exhibit signs of relapse during this medication-free trial... - Emotion recognition deficits in pediatric anxiety disorders: implications for amygdala researchJosh Easter
Section on Development and Affective Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland 20892-2670, USA
J Child Adolesc Psychopharmacol 15:563-70. 2005..CONCLUSION: As this study was conducted in a sample undergoing a neuroimaging investigation of amygdala integrity, future analyses will examine associations among amygdala function, clinical anxiety, and face-recognition abilities... - The strong situation: a potential impediment to studying the psychobiology and pharmacology of anxiety disordersShmuel Lissek
DHHS, NIH, National Institute of Mental Health, Mood and Anxiety Disorders Program, Bethesda, MD 20892 2670, USA
Biol Psychol 72:265-70. 2006.... - Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorderEllen Leibenluft
Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 164:52-60. 2007..They also compared activation in medicated versus unmedicated children with bipolar disorder and in children with bipolar disorder and attention deficit hyperactivity disorder (ADHD) versus those with bipolar disorder without ADHD... - Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorderErin B McClure
Emotional Development and Affective Neuroscience Branch, Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH DHHS, Bethesda, MD 20892, USA
Arch Gen Psychiatry 64:97-106. 2007..However, in pediatric anxiety, no research has examined attention modulation of neural response to threat cues... - An fMRI examination of developmental differences in the neural correlates of uncertainty and decision-makingAmy L Krain
NYU Child Study Center, NYU School of Medicine, New York, NY 10016, USA
J Child Psychol Psychiatry 47:1023-30. 2006..The present study examines potential developmental differences in frontal regions associated with uncertain decision-making, and tests the impact of IU on these circuits... - Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in childrenMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Biol Psychiatry 60:991-7. 2006..This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). This study examines prevalence, concurrent Axis I diagnoses, and longitudinal outcome of SMD in an epidemiologic sample... - Onset of spontaneous panic attacks: a prospective study of risk factorsWilliam Coryell
University of Iowa Carver College of Medicine, Department of Psychiatry, 2 205 MEB, Iowa City, IA 52242, USA
Psychosom Med 68:754-7. 2006..An association of those features with a subsequent onset of panic attacks would compose additional evidence that they are trait markers for panic disorder... - fMRI predictors of treatment outcome in pediatric anxiety disordersErin B McClure
Department of Psychology, Georgia State University, P O Box 5010, Atlanta, GA 30302 5010, USA
Psychopharmacology (Berl) 191:97-105. 2007..Interest has emerged in this phenomenon as a possible biological marker for individuals who are likely to benefit from tailored treatment approaches... - Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorderChristopher S Monk
Department of Psychology, University of Michigan, 2000 East Hall, 530 Church St, Ann Arbor, MI 48109, USA
Am J Psychiatry 163:1091-7. 2006.... - Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorderBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 2670, USA
Proc Natl Acad Sci U S A 103:8900-5. 2006..Results implicate deficient emotion-attention interactions in the pathophysiology of BD in youth and suggest that developmental psychobiology approaches to chronic mental illness have broad applicability... - Stress responsivity and HPA axis activity in juveniles: results from a home-based CO2 inhalation studyThomas A Terleph
NIMH, NIH, Bldg 15 K, Rm 110, MSC 2670, Bethesda, MD 20817 2670, USA
Am J Psychiatry 163:738-40. 2006..The current home-based study tested the hypothesis that parental panic disorder and offspring response to CO(2) are associated with elevated cortisol levels in juvenile offspring... - Adolescent life events as predictors of adult depressionDaniel S Pine
National Institute of Mental Health, Intramural Research Program, Building 10, Room 4N-222, Bethesda, MD 20892-1381, USA
J Affect Disord 68:49-57. 2002..However, this association with generalized anxiety disorder was limited to females. CONCLUSIONS: Life events in adolescence predict risk for major depression during early adulthood...