Bradley Peterson

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Cortical thinning in persons at increased familial risk for major depression
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 106:6273-8. 2009
  2. pmc A brain-based endophenotype for major depressive disorder
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, New York, New York 10032, USA
    Annu Rev Med 62:461-74. 2011
  3. ncbi request reprint Brain imaging studies of the anatomical and functional consequences of preterm birth for human brain development
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, Unit 74, 1051 Riverside Drive, New York, NY 10032, USA
    Ann N Y Acad Sci 1008:219-37. 2003
  4. pmc Morphologic features of the amygdala and hippocampus in children and adults with Tourette syndrome
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Arch Gen Psychiatry 64:1281-91. 2007
  5. pmc An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD
    Bradley S Peterson
    Department of Psychiatry, New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, New York, 10032, USA
    Am J Psychiatry 166:1286-94. 2009
  6. pmc A developmental fMRI study of self-regulatory control in Tourette's syndrome
    Rachel Marsh
    Department of Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 164:955-66. 2007
  7. doi request reprint An FMRI study of frontostriatal circuits during the inhibition of eye blinking in persons with Tourette syndrome
    Luigi Mazzone
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Psychiatry 167:341-9. 2010
  8. ncbi request reprint Altered interhemispheric connectivity in individuals with Tourette's disorder
    Kerstin J Plessen
    New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 161:2028-37. 2004
  9. pmc Interhemispheric connectivity and executive functioning in adults with Tourette syndrome
    Amy Margolis
    Brooklyn Learning Center, Brooklyn, NY 10032, USA
    Neuropsychology 20:66-76. 2006
  10. pmc Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder
    Kerstin J Plessen
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Gen Psychiatry 63:795-807. 2006

Research Grants

Detail Information

Publications91

  1. pmc Cortical thinning in persons at increased familial risk for major depression
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 106:6273-8. 2009
    ..These findings suggest that cortical thinning in the right hemisphere produces disturbances in arousal, attention, and memory for social stimuli, which in turn may increase the risk of developing depressive illness...
  2. pmc A brain-based endophenotype for major depressive disorder
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, New York, New York 10032, USA
    Annu Rev Med 62:461-74. 2011
    ..Identification of this endophenotype and its cognitive correlates provides targets for devising new preventive and therapeutic interventions for MDD...
  3. ncbi request reprint Brain imaging studies of the anatomical and functional consequences of preterm birth for human brain development
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, Unit 74, 1051 Riverside Drive, New York, NY 10032, USA
    Ann N Y Acad Sci 1008:219-37. 2003
    ....
  4. pmc Morphologic features of the amygdala and hippocampus in children and adults with Tourette syndrome
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Arch Gen Psychiatry 64:1281-91. 2007
    ....
  5. pmc An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD
    Bradley S Peterson
    Department of Psychiatry, New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, New York, 10032, USA
    Am J Psychiatry 166:1286-94. 2009
    ..The authors examined the effect of psychostimulants on brain activity in children and adolescents with ADHD performing the Stroop Color and Word Test...
  6. pmc A developmental fMRI study of self-regulatory control in Tourette's syndrome
    Rachel Marsh
    Department of Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 164:955-66. 2007
    ..The purpose of this study was to examine the age correlates of functional activity in neural circuits that subserve self-regulatory control in children and adults with Tourette's syndrome...
  7. doi request reprint An FMRI study of frontostriatal circuits during the inhibition of eye blinking in persons with Tourette syndrome
    Luigi Mazzone
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Psychiatry 167:341-9. 2010
    ..The authors sought to study activity in neural circuits that subserve the inhibition of a semi-involuntary motor behavior, eye blinking, in children and adults with Tourette syndrome and in healthy comparison subjects...
  8. ncbi request reprint Altered interhemispheric connectivity in individuals with Tourette's disorder
    Kerstin J Plessen
    New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 161:2028-37. 2004
    ..The authors assessed corpus callosum size and anatomical connectivity across the cerebral hemispheres in persons with Tourette's disorder...
  9. pmc Interhemispheric connectivity and executive functioning in adults with Tourette syndrome
    Amy Margolis
    Brooklyn Learning Center, Brooklyn, NY 10032, USA
    Neuropsychology 20:66-76. 2006
    ..In the control group only, better left-hand performance accompanied larger PFC volumes but not CC cross-sectional area. PFC dysfunction might have precluded executive control of interference in the TS group...
  10. pmc Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder
    Kerstin J Plessen
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Gen Psychiatry 63:795-807. 2006
    ....
  11. doi request reprint Basal ganglia surface morphology and the effects of stimulant medications in youth with attention deficit hyperactivity disorder
    Loren J Sobel
    Department of Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Psychiatry 167:977-86. 2010
    ..The authors examined the morphologic features of the basal ganglia nuclei (caudate, putamen, and globus pallidus) in children with ADHD...
  12. pmc Identification of a circuit-based endophenotype for familial depression
    Marc J Dubin
    The New York State Psychiatric Institute, New York, NY 10032, USA
    Psychiatry Res 201:175-81. 2012
    ..These findings support a model of pathogenesis in which hypoplasia within a neural network for attention and emotional processing predisposes to depression...
  13. ncbi request reprint Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Gen Psychiatry 60:1201-8. 2003
    ..Appreciation of whether volumetric abnormalities are early features of BD or whether the abnormalities represent neurodegenerative changes associated with illness duration is limited by the paucity of data in juvenile samples...
  14. pmc Increased number of subcortical hyperintensities on MRI in children and adolescents with Tourette's syndrome, obsessive-compulsive disorder, and attention deficit hyperactivity disorder
    Jose A Amat
    Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 163:1106-8. 2006
    ..To investigate whether cerebral hyperintensities on T2-weighted magnetic resonance images (MRI) are associated with childhood neuropsychiatric disorders...
  15. doi request reprint Neuropsychological near normality and brain structure abnormality in schizophrenia
    Bruce E Wexler
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park St, New Haven, CT 06519, USA
    Am J Psychiatry 166:189-95. 2009
    ....
  16. pmc The circumplex model of affect: an integrative approach to affective neuroscience, cognitive development, and psychopathology
    Jonathan Posner
    Columbia College of Physicians and Surgeons, New York, NY 10032, USA
    Dev Psychopathol 17:715-34. 2005
    ..Moreover, the model offers new theoretical and empirical approaches to studying the development of affective disorders as well as the genetic and cognitive underpinnings of affective processing within the central nervous system...
  17. ncbi request reprint An FMRI Stroop task study of ventromedial prefrontal cortical function in pathological gamblers
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Am J Psychiatry 160:1990-4. 2003
    ..The authors used the Stroop paradigm to test attention and response inhibition during the presentation of congruent and incongruent stimuli in male pathological gamblers and a group of comparison subjects...
  18. pmc Correction of eddy-current distortions in diffusion tensor images using the known directions and strengths of diffusion gradients
    Jiancheng Zhuang
    Magnetic Resonance Imaging Unit, Department of Psychiatry, Columbia College of Physicians and Surgeons, New York, New York, USA
    J Magn Reson Imaging 24:1188-93. 2006
    ..To correct eddy-current artifacts in diffusion tensor (DT) images without the need to obtain auxiliary scans for the sole purpose of correction...
  19. doi request reprint Enlargement of thalamic nuclei in Tourette syndrome
    Ann M Miller
    Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, USA
    Arch Gen Psychiatry 67:955-64. 2010
    ..Previous imaging studies have shown modifications of the basal ganglia and cortical targets in individuals with Tourette syndrome (TS), but less is known regarding the role of the thalamus in TS pathogenesis...
  20. doi request reprint A slice of pi : an exploratory neuroimaging study of digit encoding and retrieval in a superior memorist
    Amir Raz
    MRI Unit in the Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA
    Neurocase 15:361-72. 2009
    ....
  21. pmc A developmental fMRI study of self-regulatory control
    Rachel Marsh
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Hum Brain Mapp 27:848-63. 2006
    ....
  22. pmc The rapid and automatic combination of proton MRSI data using multi-channel coils without water suppression
    Zhengchao Dong
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Magn Reson Imaging 25:1148-54. 2007
    ....
  23. pmc Neuroimaging studies of normal brain development and their relevance for understanding childhood neuropsychiatric disorders
    Rachel Marsh
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, The New York State Psychiatric Institute, and The College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 47:1233-51. 2008
    ..To review the maturational events that occur during prenatal and postnatal brain development and to present neuroimaging findings from studies of healthy individuals that identify the trajectories of normal brain development...
  24. doi request reprint Neural systems subserving valence and arousal during the experience of induced emotions
    Tiziano Colibazzi
    Division of Child and Adolescent Psychiatry, The New York State Psychiatric Institute, Columbia College of Physicians and Surgeons, New York, NY 10032, USA
    Emotion 10:377-89. 2010
    ....
  25. pmc Unifying the analyses of anatomical and diffusion tensor images using volume-preserved warping
    Dongrong Xu
    MRI Unit, College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, New York, USA
    J Magn Reson Imaging 25:612-24. 2007
    ....
  26. pmc Statistical analyses of brain surfaces using Gaussian random fields on 2-D manifolds
    Ravi Bansal
    New York State Psychiatric Institute, New York, NY 10032, USA
    IEEE Trans Med Imaging 26:46-57. 2007
    ....
  27. pmc Voxel-wise comparisons of the morphology of diffusion tensors across groups of experimental subjects
    Ravi Bansal
    New York State Psychiatric Institute, New York, NY 10032, USA
    Psychiatry Res 156:225-45. 2007
    ..Finally, analyses of in vivo DT data using our method reveal significant between-group differences in diffusivity along fiber tracts within white matter, whereas analyses based on FA values failed to detect some of these differences...
  28. pmc Partner-matching for the automated identification of reproducible ICA components from fMRI datasets: algorithm and validation
    Zhishun Wang
    The MRI Unit and The Division of Child and Adolescent Psychiatry, Columbia University, New York, New York, USA
    Hum Brain Mapp 29:875-93. 2008
    ....
  29. pmc Inhibitory deficits in Tourette's syndrome
    Emily R Stern
    Department of Psychiatry, University of Michigan, 4250 Plymouth Road, 2701 Rachel Upjohn Building, Ann Arbor, MI 48109, USA
    Dev Psychobiol 50:9-18. 2008
    ..In particular, we will consider the extent to which the cognitive and emotional development of persons with TS may be affected by specific neurobiological characteristics of the disorder...
  30. pmc Study of the development of fetal baboon brain using magnetic resonance imaging at 3 Tesla
    Feng Liu
    Department of Psychiatry, New York State Psychiatric Institute, Columbia University Medical Center, 1051 Riverside Drive, New York, NY 10032, USA
    Neuroimage 40:148-59. 2008
    ..This protocol for in utero MRI of fetal baboon brains will help to advance the use of nonhuman primate models to study fetal brain development longitudinally...
  31. pmc Spectral resolution amelioration by deconvolution (SPREAD) in MR spectroscopic imaging
    Zhengchao Dong
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Magn Reson Imaging 29:1395-405. 2009
    ..To develop, implement, and evaluate a novel postprocessing method for enhancing the spectral resolution of in vivo MR spectroscopic imaging (MRSI) data...
  32. pmc Functional disturbances within frontostriatal circuits across multiple childhood psychopathologies
    Rachel Marsh
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Dr, Unit 74, New York, NY 10032, USA
    Am J Psychiatry 166:664-74. 2009
    ..Findings from these studies can be used as a reference frame against which to compare the aberrant development of these processes in individuals across a wide range of childhood psychopathologies...
  33. pmc Calculation of the confidence intervals for transformation parameters in the registration of medical images
    Ravi Bansal
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Med Image Anal 13:215-33. 2009
    ..Thus, our method precisely quantified confidence in the registration of images that contain varying amounts of misregistration and varying anatomy across individuals...
  34. pmc Normal development of brain circuits
    Gregory Z Tau
    Division of Child and Adolescent Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY, USA
    Neuropsychopharmacology 35:147-68. 2010
    ....
  35. pmc The ellipsoidal area ratio: an alternative anisotropy index for diffusion tensor imaging
    Dongrong Xu
    MRI Unit, Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Magn Reson Imaging 27:311-23. 2009
    ....
  36. doi request reprint Cerebellar morphology in Tourette syndrome and obsessive-compulsive disorder
    Russell H Tobe
    Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    Ann Neurol 67:479-87. 2010
    ..Few studies, however, have investigated the role of the cerebellum in Tourette syndrome (TS), a condition defined by the presence of semi-involuntary movements and sounds...
  37. pmc A virtual reality-based FMRI study of reward-based spatial learning
    Rachel Marsh
    The MRI Unit, Division of Child and Adolescent Psychiatry, Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, United States
    Neuropsychologia 48:2912-21. 2010
    ....
  38. ncbi request reprint What is an image?
    Andrew J Gerber
    Division of Child and Adolescent Psychiatry, Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 47:245-8. 2008
  39. pmc An affective circumplex model of neural systems subserving valence, arousal, and cognitive overlay during the appraisal of emotional faces
    Andrew J Gerber
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, Division of Child and Adolescent Psychiatry, New York, NY 10032, USA
    Neuropsychologia 46:2129-39. 2008
    ..The simultaneous assessment of the effects of arousal and valence proved essential for the identification of neural systems contributing to the processing of emotional faces...
  40. pmc The neurophysiological bases of emotion: An fMRI study of the affective circumplex using emotion-denoting words
    Jonathan Posner
    Columbia College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
    Hum Brain Mapp 30:883-95. 2009
    ..Based on the circumplex model, we predicted a linear relationship between neural activity and incremental changes in these two affective dimensions...
  41. pmc Deficient activity in the neural systems that mediate self-regulatory control in bulimia nervosa
    Rachel Marsh
    Department of Psychiatry, New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, New York, New York
    Arch Gen Psychiatry 66:51-63. 2009
    ..Disturbances in neural systems that mediate voluntary self-regulatory processes may contribute to bulimia nervosa (BN) by releasing feeding behaviors from regulatory control...
  42. pmc Seamless warping of diffusion tensor fields
    Dongrong Xu
    MRI Unit, Columbia University Department of Psychiatry, and New York State Psychiatric Institute, Unit 74, New York, NY 10032, USA
    IEEE Trans Med Imaging 27:285-99. 2008
    ..Once the bijection has been achieved and tensors have been correctly relocated to the template space, we can appropriately reorient tensors in the template space using a warping method based on Procrustean estimation...
  43. pmc Using Perturbation theory to reduce noise in diffusion tensor fields
    Ravi Bansal
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Med Image Anal 13:580-97. 2009
    ....
  44. ncbi request reprint Perceptual-motor skill learning in Gilles de la Tourette syndrome. Evidence for multiple procedural learning and memory systems
    Rachel Marsh
    The Division of Child and Adolescent Psychiatry in the Department of Psychiatry, The New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 74, New York, NY 10032, USA
    Neuropsychologia 43:1456-65. 2005
    ....
  45. ncbi request reprint Ecological nuances in functional magnetic resonance imaging (fMRI): psychological stressors, posture, and hydrostatics
    Amir Raz
    MRI Unit, Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 74, New York, NY 10032, USA
    Neuroimage 25:1-7. 2005
    ..Recognizing the central role of fMRI in unraveling the neural mechanisms of cognition, we outline ways to address these limitations...
  46. ncbi request reprint ROC-based assessments of 3D cortical surface-matching algorithms
    Ravi Bansal
    New York State Psychiatric Institute, New York, NY 10032, USA
    Neuroimage 24:150-62. 2005
    ..The GD and NN algorithms, moreover, are both vulnerable to detecting false-positive activations at points of high curvature, particularly along large fissures, cisterns, and cortical sulci...
  47. ncbi request reprint Habit learning in Tourette syndrome: a translational neuroscience approach to a developmental psychopathology
    Rachel Marsh
    Division of Child and Adolescent Psychiatry in the Department of Psychiatry, New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, New York 10032, USA
    Arch Gen Psychiatry 61:1259-68. 2004
    ..The etiology of Tourette syndrome (TS) involves disturbances in the structure and function of the basal ganglia. The basal ganglia mediate habit learning...
  48. ncbi request reprint A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 60:601-9. 2003
    ..We sought to characterize state- and trait-related functional impairment in frontal systems in bipolar disorder...
  49. ncbi request reprint Neuroimaging of developmental psychopathologies: the importance of self-regulatory and neuroplastic processes in adolescence
    Alexandra L Spessot
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, Unit 74, 1051 Riverside Drive, New York, NY 10032, USA
    Ann N Y Acad Sci 1021:86-104. 2004
    ....
  50. ncbi request reprint A functional magnetic resonance imaging study of language processing and its cognitive correlates in prematurely born children
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, New York 10032, USA
    Pediatrics 110:1153-62. 2002
    ..Our aim was to compare brain activity associated with phonologic and semantic processing of language between term and preterm children using functional magnetic resonance imaging (fMRI)...
  51. ncbi request reprint Conceptual, methodological, and statistical challenges in brain imaging studies of developmentally based psychopathologies
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and New York State Psychiatric Institute, New York, NY 10032, USA
    Dev Psychopathol 15:811-32. 2003
    ....
  52. ncbi request reprint Basal Ganglia volumes in patients with Gilles de la Tourette syndrome
    Bradley S Peterson
    Division of Child and Adolescent Psychiatry, The Department of Psychiatry, New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, New York 10032, USA
    Arch Gen Psychiatry 60:415-24. 2003
    ....
  53. ncbi request reprint Regional brain volumes and their later neurodevelopmental correlates in term and preterm infants
    Bradley S Peterson
    Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, New York 10032, USA
    Pediatrics 111:939-48. 2003
    ..To compare regional brain volumes measured in term and preterm infants, and to correlate regional volumes with measures of neurodevelopmental outcome...
  54. ncbi request reprint Indeterminacy & compromise formation: implications for a psychoanalytic theory of mind
    Bradley S Peterson
    Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, Unit 74, New York, NY 10032, USA
    Int J Psychoanal 83:1017-35. 2002
    ..This simultaneous gratification afforded by compromise formation is why neurotic symptoms are so intractable to treatment. If conflict is one defining feature of the mind, then indeterminacy and compromise formation are the others...
  55. pmc Cortisol levels and hippocampus volumes in healthy preadolescent children
    Christoph P Wiedenmayer
    Department of Psychiatry, Columbia University, New York, New York 10032, USA
    Biol Psychiatry 60:856-61. 2006
    ..The objective of this study was to examine possible associations of serum cortisol levels with hippocampal volumes and morphology in healthy children...
  56. ncbi request reprint An event-related functional MRI study comparing interference effects in the Simon and Stroop tasks
    Bradley S Peterson
    The Division of Child and Adolescent Psychiatry, Department of Psychiatry, the New York State Psychiatric Institute and the College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Brain Res Cogn Brain Res 13:427-40. 2002
    ..Therefore, despite the widely differing stimulus characteristics employed by these tasks, the neural systems that subserve successful task performance are likely to be similar as well...
  57. pmc A statistical framework for the classification of tensor morphologies in diffusion tensor images
    Hongtu Zhu
    MRI Unit, Department of Psychiatry, Columbia University Medical Center, USA
    Magn Reson Imaging 24:569-82. 2006
    ..We also show that the P values for test statistics are more sensitive tools for classifying tensor morphologies than are invariant measures of anisotropy alone...
  58. doi request reprint Automated artifact detection and removal for improved tensor estimation in motion-corrupted DTI data sets using the combination of local binary patterns and 2D partial least squares
    Zhenyu Zhou
    MRI Unit, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Magn Reson Imaging 29:230-42. 2011
    ..g., the bootstrapping estimation) that use univariate or multivariate regression methods to fit MRI data to a pre-specified model...
  59. pmc An improved representation of regional boundaries on parcellated morphological surfaces
    Xuejun Hao
    MRI Unit, Psychiatry Department, Columbia University and the New York State Psychiatric Institute, USA
    Comput Med Imaging Graph 35:206-19. 2011
    ....
  60. ncbi request reprint Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, VA Depression Research Center REAP, VA Connecticut Healthcare System 116 A, 950 Campbell Avenue, West Haven, CT 06516, USA
    Ann N Y Acad Sci 1021:376-83. 2004
    ..This potential neurodevelopmental model for BD could have important implications for the recognition of early signs of the disorder and for age-specific treatment strategies...
  61. pmc Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Bipolar Disord 7:570-6. 2005
    ..Here we use a within-subject longitudinal design to investigate whether amygdala volume abnormalities persist in adolescents and young adults with BD over a time interval of approximately 2 years...
  62. pmc Correlates of intellectual ability with morphology of the hippocampus and amygdala in healthy adults
    Jose A Amat
    The Division of Child Psychiatry in the Department of Psychiatry, Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY 10032, USA
    Brain Cogn 66:105-14. 2008
    ..These findings suggest that a smaller anterior hippocampus contributes to an increased efficiency of neural processing that subserves overall intelligence...
  63. pmc Latent volumetric structure of the human brain: Exploratory factor analysis and structural equation modeling of gray matter volumes in healthy children and adults
    Tiziano Colibazzi
    The New York State Psychiatric Institute and Columbia College of Physician and Surgeons, New York, New York 10032, USA
    Hum Brain Mapp 29:1302-12. 2008
    ..These modeling techniques may prove useful in the future for the study of structural networks in disease populations...
  64. pmc The neural bases of obsessive-compulsive disorder in children and adults
    Tiago V Maia
    Columbia University and New York State Psychiatric Institute, NY 10032, USA
    Dev Psychopathol 20:1251-83. 2008
    ..Converging evidence from these various lines of research supports a causal role for the cortico-basal ganglia-thalamo-cortical loops that involve the OFC and ACC in the pathogenesis of OCD in children and adults...
  65. doi request reprint Brain morphometry using anatomical magnetic resonance imaging
    Ravi Bansal
    The authors are with the Department of Psychiatry, Columbia University, New York
    J Am Acad Child Adolesc Psychiatry 47:619-21. 2008
  66. doi request reprint Techniques for in utero, longitudinal MRI of fetal brain development in baboons at 3T
    Feng Liu
    Department of Psychiatry, Columbia University Medical Center, New York, NY 10032, USA
    Methods 50:147-56. 2010
    ..In conclusion, in utero MRI of fetal baboon brains greatly enhances the use of nonhuman primate models to study fetal brain development longitudinally...
  67. ncbi request reprint Detection of functional connectivity using temporal correlations in MR images
    Michelle Hampson
    Department of Diagnostic Radiology, Yale University School of Medicine, 333 Cedar Street, Fitkin Basement, PO Box 208042, New Haven, CT 06520 8042, USA
    Hum Brain Mapp 15:247-62. 2002
    ..These findings suggest that the proposed methodology can reveal the presence and strength of functional connections in high-level cognitive systems...
  68. ncbi request reprint Assessment of symptom exacerbations in a longitudinal study of children with Tourette's syndrome or obsessive-compulsive disorder
    Haiqun Lin
    Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 41:1070-7. 2002
    ..A second major aim was to assess whether fluctuations in tic and OC symptom severity covaried with one another...
  69. ncbi request reprint Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment
    Denis G Sukhodolsky
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 42:98-105. 2003
    ..To examine the association of disruptive behavior with social, adaptive, and family functioning in Tourette's syndrome (TS) with and without comorbid attention-deficit/hyperactivity disorder (ADHD)...
  70. ncbi request reprint Neural and behavioral substrates of mood and mood regulation
    Richard J Davidson
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Biol Psychiatry 52:478-502. 2002
    ..Training interdisciplinary clinical scientists who meaningfully draw upon both behavioral and neuroscientific literatures and methods is critically required for the realization of these goals...
  71. ncbi request reprint Detecting determinism in short time series, with an application to the analysis of a stationary EEG recording
    Jaeseung Jeong
    National Creative Research Initiative, Center for Neurodynamics and Department of Physics, Korea University, Seoul 136 701, South Korea
    Biol Cybern 86:335-42. 2002
    ..This method can be used to analyze determinism in short time series, such as those from physiological recordings, that can be modeled using differentiable dynamical processes...
  72. ncbi request reprint Mapping cortical gray matter asymmetry patterns in adolescents with heavy prenatal alcohol exposure
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California at Los Angeles, 90095, USA
    Neuroimage 17:1807-19. 2002
    ....
  73. ncbi request reprint Mapping cortical change across the human life span
    Elizabeth R Sowell
    University of California at Los Angeles, Laboratory of Neuro Imaging, Department of Neurology, 710 Westwood Plaza, Los Angeles, California 90095, USA
    Nat Neurosci 6:309-15. 2003
    ..Our findings also indicate that the posterior temporal cortices, primarily in the left hemisphere, which typically support language functions, have a more protracted course of maturation than any other cortical region...
  74. ncbi request reprint Sex and spatial position effects on object location memory following intentional learning of object identities
    Gerianne M Alexander
    Yale Child Study Center, New Haven, CT 06520, USA
    Neuropsychologia 40:1516-22. 2002
    ....
  75. ncbi request reprint A method for determinism in short time series, and its application to stationary EEG
    Jaeseung Jeong
    National Creative Research Initiative Center for Neuro dynamics, Department of Physics, Korea University, Seoul 136 701 South Korea
    IEEE Trans Biomed Eng 49:1374-9. 2002
    ..This method can be useful for analyzing determinism in short time series, such as those from physiological recordings...
  76. ncbi request reprint Testing the prenatal hormone hypothesis of tic-related disorders: gender identity and gender role behavior
    Gerianne M Alexander
    Texas A and M University, Department of Psychology, College Station, 77843, USA
    Dev Psychopathol 16:407-20. 2004
    ..These findings therefore support the hypothesis that an altered androgen-dependent process of sexual differentiation during prenatal life may contribute to the development of tic-related disorders...
  77. pmc Ferritin levels and their association with regional brain volumes in Tourette's syndrome
    Daniel A Gorman
    Department of Psychiatry, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Am J Psychiatry 163:1264-72. 2006
    ..The authors measured peripheral iron indices in a large group of Tourette's syndrome and comparison subjects and explored associations of ferritin levels with regional brain volumes...
  78. pmc Functional brain asymmetry, attentional modulation, and interhemispheric transfer in boys with Tourette syndrome
    Kerstin J Plessen
    Center for Child and Adolescent Mental Health, University of Bergen, Norway
    Neuropsychologia 45:767-74. 2007
    ..When instructed to focus attention on the left ear stimulus, however, performance deteriorated in the TS group. Correlations with CC area further supported the hypothesized presence of deviant callosal functioning in the TS group...
  79. pmc A statistical analysis of brain morphology using wild bootstrapping
    Hongtu Zhu
    Department of Biostatistics and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, NC 27599 7420, USA
    IEEE Trans Med Imaging 26:954-66. 2007
    ..We demonstrate the application of this robust test procedure to the detection of statistically significant differences in the morphology of the hippocampus over time across gender groups in a large sample of healthy subjects...
  80. pmc Neuroimaging of tic disorders with co-existing attention-deficit/hyperactivity disorder
    Kerstin J Plessen
    Center for Child and Adolescent Mental Health, University of Bergen, Norway
    Eur Child Adolesc Psychiatry 16:60-70. 2007
    ..Recently, both conditions have been subject to neuroimaging studies, with the aim of understanding their underlying neurobiological correlates...
  81. pmc Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome
    Michael H Bloch
    Child Study Center, Yale University School of Medicine, New Haven, CT, USA
    Neurology 65:1253-8. 2005
    ..Currently no clinical measures can predict whose tic symptoms will persist into adulthood. Previous cross-sectional imaging studies have identified reduced caudate nucleus volumes in subjects with TS...
  82. pmc Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87 years of age
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 17:1550-60. 2007
    ..Given the large sample and the large range of ages studied, these results help to address controversies in the study of central nervous system sexual dimorphisms...
  83. pmc Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome
    Michael H Bloch
    Yale Child Study Center, and General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    Arch Pediatr Adolesc Med 160:65-9. 2006
    ..One half to two thirds of children with TS experience a reduction or complete resolution of tic symptoms during adolescence. At least one third of adults with TS have comorbid obsessive-compulsive disorder (OCD)...
  84. pmc Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder
    Denis G Sukhodolsky
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    Am J Psychiatry 162:1125-32. 2005
    ....
  85. pmc Thinning of sensorimotor cortices in children with Tourette syndrome
    Elizabeth R Sowell
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, 635 Charles Young Drive South, Suite 225, Los Angeles, California 90095, USA
    Nat Neurosci 11:637-9. 2008
    ..Correlations of cortical thickness in sensorimotor regions with tic symptoms suggest that these brain regions are important in the pathogenesis of Tourette syndrome...
  86. ncbi request reprint Dimensional complexity of the EEG in patients with posttraumatic stress disorder
    Jeong Ho Chae
    Department of Psychiatry, College of Medicine, Catholic University of Korea, Seoul, South Korea
    Psychiatry Res 131:79-89. 2004
    ..This study supports the hypotheses that PTSD patients exhibit disturbed cortical information processing, and that non-linear dynamical analysis of the EEG can be a tool for detecting changes in neurodynamics of the brain in PTSD...
  87. pmc A note on the validity of statistical bootstrapping for estimating the uncertainty of tensor parameters in diffusion tensor images
    Ying Yuan
    Department of Statistics and Operations, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    IEEE Trans Med Imaging 27:1506-14. 2008
    ..Our findings raise serious concerns about the use of bootstrap methods to quantify the uncertainty of fiber pathways when those pathways pass through voxels that contain either isotropic tensors, oblate tensors, or multiple tensors...
  88. ncbi request reprint Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder
    Elizabeth R Sowell
    University of California at Los Angeles, Laboratory of Neuro Imaging, Department of Neurology, 710 Westwood Plaza, Room 4 238, Los Angeles, CA 90095 1769, USA
    Lancet 362:1699-707. 2003
    ..We aimed to map these features in patients with attention-deficit hyperactivity disorder...
  89. ncbi request reprint Cavum septi pellucidi in Tourette syndrome
    Karen J Kim
    Department of Internal Medicine, University of California San Francisco, San Francisco, California, USA
    Biol Psychiatry 54:76-85. 2003
    ..The goal of this study was to characterize systematically the CSP and the related cavum vergae in individuals with Tourette syndrome (TS)...
  90. ncbi request reprint Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI
    Hilary P Blumberg
    Department of Psychiatry and Diagnostic Radiology and the Yale Child Study Center, Yale University School of Medicine, New Haven, Conn, 06516, USA
    Am J Psychiatry 160:1345-7. 2003
    ..This study investigated whether the functional abnormalities in prefrontal systems observed in adult bipolar disorder are manifested in adolescents with this illness...
  91. pmc A functional magnetic resonance imaging study of the long-term influences of early indomethacin exposure on language processing in the brains of prematurely born children
    Laura R Ment
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, New Haven, Connecticut 06520, USA
    Pediatrics 118:961-70. 2006
    ..Previous studies have demonstrated that indomethacin lowers the incidence and decreases the severity of intraventricular hemorrhage, as well as improves the cognitive outcome, in prematurely born male infants...

Research Grants18

  1. Neuroanatomical MRI Studies of Childhood Disorders
    Bradley Peterson; Fiscal Year: 2007
    ....
  2. MRI of Infants Exposed Prenatally to Drugs of Abuse
    Bradley Peterson; Fiscal Year: 2007
    ..Defining these consequences will in turn help to identify the pathophysiological mediators and suggest possible prevention and early intervention strategies. ..
  3. MRI IN CHILDHOOD NEUROPSYCHIATRIC DISORDERS
    Bradley Peterson; Fiscal Year: 2007
    ....
  4. FMRI STUDIES OF IMPULSE CONTROL IN CHILDHOOD DISORDERS
    Bradley Peterson; Fiscal Year: 2002
    ..These studies should provide important new insights into the underlying neurobiological basis of each disorder. ..
  5. Identifying Brain-Based Biomarkers for ASD & their Biological Subtypes
    Bradley S Peterson; Fiscal Year: 2010
    ..Our proposed research plan will advance public health by enabling strategies for prevention, early detection, and personalized treatment of ASDs. ..