- JISTIC: identification of significant targets in cancerFelix Sanchez-Garcia
Department of Computer Science, Columbia University, New York, NY, USA
BMC Bioinformatics 11:189. 2010..As datasets measuring copy number aberrations in tumors accumulate, a major challenge has become to distinguish between those mutations that drive the cancer versus those passenger mutations that have no effect...
- Principles and strategies for developing network models in cancerDana Pe'er
Department of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, New York, NY 10027, USA
Cell 144:864-73. 2011..In conclusion, we discuss how a network-level understanding of cancer can be used to predict drug response and guide therapeutics...