Gustavo Palacios

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA
    PLoS ONE 4:e8540. 2009
  2. ncbi request reprint Microbe hunting in laboratory animal research
    Gustavo Palacio
    Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    ILAR J 51:245-54. 2010
  3. pmc Genetic analysis of Israel acute paralysis virus: distinct clusters are circulating in the United States
    G Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    J Virol 82:6209-17. 2008
  4. pmc Characterization of the Candiru antigenic complex (Bunyaviridae: Phlebovirus), a highly diverse and reassorting group of viruses affecting humans in tropical America
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th St, Rm 1709, New York, NY 10032, USA
    J Virol 85:3811-20. 2011
  5. pmc Aguacate virus, a new antigenic complex of the genus Phlebovirus (family Bunyaviridae)
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 92:1445-53. 2011
  6. ncbi request reprint Enteroviruses as agents of emerging infectious diseases
    G Palacios
    Jerome L and Dawn Greene Infectious Disease Laboratory, Columbia University, New York, New York 10032, USA
    J Neurovirol 11:424-33. 2005
  7. pmc Human metapneumovirus infection in wild mountain gorillas, Rwanda
    Gustavo Palacios
    Center for Infection and Immunity, Columbia University, Rm 1709, 722 W 168th St, New York, NY 10032, USA
    Emerg Infect Dis 17:711-3. 2011
  8. pmc Molecular identification of mumps virus genotypes from clinical samples: standardized method of analysis
    G Palacios
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 W 168th Street, Fl 18, New York, NY 10032, USA
    J Clin Microbiol 43:1869-78. 2005
  9. pmc Rapid molecular strategy for orbivirus detection and characterization
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    J Clin Microbiol 49:2314-7. 2011
  10. pmc Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus)
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 92:2558-65. 2011

Detail Information

Publications43

  1. pmc Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA
    PLoS ONE 4:e8540. 2009
    ..Furthermore, no evidence was found for increased frequency of risk factors for H1N1pdm disease...
  2. ncbi request reprint Microbe hunting in laboratory animal research
    Gustavo Palacio
    Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    ILAR J 51:245-54. 2010
    ..To illustrate the complexity of pursuing pathogen discovery research, we include examples from our own work that are intended to provide insights into the process that led to the selection of particular strategies...
  3. pmc Genetic analysis of Israel acute paralysis virus: distinct clusters are circulating in the United States
    G Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    J Virol 82:6209-17. 2008
    ..Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence...
  4. pmc Characterization of the Candiru antigenic complex (Bunyaviridae: Phlebovirus), a highly diverse and reassorting group of viruses affecting humans in tropical America
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th St, Rm 1709, New York, NY 10032, USA
    J Virol 85:3811-20. 2011
    ..This high rate of reassortment illustrates the inaccuracy of a classification system based solely on antigenic relationships...
  5. pmc Aguacate virus, a new antigenic complex of the genus Phlebovirus (family Bunyaviridae)
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 92:1445-53. 2011
    ..collected in Central and South America. Aguacate virus appears to be a natural reassortant and serves as one more example of the high frequency of reassortment in this genus...
  6. ncbi request reprint Enteroviruses as agents of emerging infectious diseases
    G Palacios
    Jerome L and Dawn Greene Infectious Disease Laboratory, Columbia University, New York, New York 10032, USA
    J Neurovirol 11:424-33. 2005
    ..These links between enterovirus infections and emerging diseases are reviewed...
  7. pmc Human metapneumovirus infection in wild mountain gorillas, Rwanda
    Gustavo Palacios
    Center for Infection and Immunity, Columbia University, Rm 1709, 722 W 168th St, New York, NY 10032, USA
    Emerg Infect Dis 17:711-3. 2011
    ..Surveillance is needed to ensure survival of these critically endangered animals...
  8. pmc Molecular identification of mumps virus genotypes from clinical samples: standardized method of analysis
    G Palacios
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 W 168th Street, Fl 18, New York, NY 10032, USA
    J Clin Microbiol 43:1869-78. 2005
    ..This PCR assay for characterization of mumps infections coupled to a web-based analytical program provides a rapid method for identification of known and novel strains...
  9. pmc Rapid molecular strategy for orbivirus detection and characterization
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    J Clin Microbiol 49:2314-7. 2011
    ..Phylogenetic assignment is achieved by automated Web-based sequence analysis of amplification products...
  10. pmc Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus)
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 92:2558-65. 2011
    ..Phylogenetic analysis revealed similarities between SSRV and orthoreoviruses of birds, bats and other mammals that suggests potential for interspecies transmission...
  11. pmc Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South Africa
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 91:1315-24. 2010
    ..We propose MWV as a tentative novel species in the Lassa-lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics...
  12. pmc Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray
    Phenix lan Quan
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    J Clin Microbiol 45:2359-64. 2007
    ..Twenty-one different respiratory virus species were accurately characterized, including a recently identified novel genetic clade of rhinovirus...
  13. ncbi request reprint MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in New York State during 2004-2005
    Daryl Lamson
    Clinical Virology Program, Wadsworth Center, New York State Department of Health, Albany, NY, USA
    J Infect Dis 194:1398-402. 2006
    ..In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management...
  14. pmc Genomic and antigenic characterization of Jos virus
    Ana Valeria Bussetti
    Center for Infection and Immunity and WHO Collaborating Centre for Diagnostics, Surveillance and Immunotherapeutics for Emerging Infectious and Zoonotic Diseases, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 93:293-8. 2012
    ..Here, we report genetic, ultrastructural and serological evidence that JOSV is an orthomyxovirus distinct from but phylogenetically related to viruses of the genus Thogotovirus...
  15. pmc Greene SCPrimer: a rapid comprehensive tool for designing degenerate primers from multiple sequence alignments
    Omar J Jabado
    Jerome L and Dawn Greene Laboratory for Infectious Diseases, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Nucleic Acids Res 34:6605-11. 2006
    ....
  16. pmc Global distribution of novel rhinovirus genotype
    Thomas Briese
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 14:944-7. 2008
    ..Molecular dating indicates that these viruses have been circulating for at least 250 years...
  17. doi request reprint A new arenavirus in a cluster of fatal transplant-associated diseases
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    N Engl J Med 358:991-8. 2008
    ..Culture, polymerase-chain-reaction (PCR) and serologic assays, and oligonucleotide microarray analysis for a wide range of infectious agents were not informative...
  18. pmc Nonparametric methods for the analysis of single-color pathogen microarrays
    Omar J Jabado
    Center for Infection and Immunity Mailman School of Public Health Columbia University New York, NY, USA
    BMC Bioinformatics 11:354. 2010
    ..Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied...
  19. pmc Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia
    Nazir Savji
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Gen Virol 92:1676-87. 2011
    ..Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex...
  20. pmc Comprehensive viral oligonucleotide probe design using conserved protein regions
    Omar J Jabado
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    Nucleic Acids Res 36:e3. 2008
    ..In silico testing using an experimentally derived thermodynamic model indicated near complete coverage of the viral sequence database...
  21. pmc Rapid molecular strategy for filovirus detection and characterization
    Junhui Zhai
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Clin Microbiol 45:224-6. 2007
    ..Phylogenetic assignment is achieved by automated web-based sequence analysis of amplification products...
  22. ncbi request reprint Genetic detection and characterization of lujo virus, a new hemorrhagic Fever-associated arenavirus from southern Africa
    Thomas Briese
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS Pathog 5:e1000455. 2009
    ..LUJV is a novel, genetically distinct, highly pathogenic arenavirus...
  23. pmc Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa
    Thomas Briese
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
    PLoS Pathog 5:e1000455. 2009
    ..LUJV is a novel, genetically distinct, highly pathogenic arenavirus...
  24. doi request reprint Astrovirus encephalitis in boy with X-linked agammaglobulinemia
    Phenix lan Quan
    Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 16:918-25. 2010
    ..Our findings expand the spectrum of causative agents associated with encephalitis and highlight unbiased molecular technology as a valuable tool for differential diagnosis of unexplained disease...
  25. doi request reprint Rapid sequence-based diagnosis of viral infection
    Phenix lan Quan
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Antiviral Res 79:1-5. 2008
    ..Here we review the current status of viral diagnostics and the utility of various sequence-based diagnostic platforms for applications in clinical microbiology, surveillance and pathogen discovery...
  26. pmc Panmicrobial oligonucleotide array for diagnosis of infectious diseases
    Gustavo Palacios
    Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 13:73-81. 2007
    ....
  27. pmc Diversity and distribution of hantaviruses in South America
    Cadhla Firth
    Center for Infection and Immunity, Columbia University, New York, New York, USA
    J Virol 86:13756-66. 2012
    ....
  28. ncbi request reprint Severe acute respiratory syndrome coronavirus persistence in Vero cells
    Gustavo Palacios
    Greene Infectious Disease Laboratory, Mailman School of Public Health and Department of Epidemiology, Columbia University, NY 10032, USA
    Chin Med J (Engl) 118:451-9. 2005
    ..This study was conducted to investigate viral persistence...
  29. pmc MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever
    Gustavo Palacios
    Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 12:692-5. 2006
    ..We describe a diagnostic system for rapid, multiplex polymerase chain reaction identification of 10 different causes of viral hemorrhagic fevers...
  30. doi request reprint Diagnostics and discovery in viral hemorrhagic fevers
    W Ian Lipkin
    Center for Infection and Immunity, Mailman School of Public Health of Columbia University, New York, New York, USA
    Ann N Y Acad Sci 1171:E6-11. 2009
    ..This chapter reviews recent progress in the field of pathogen surveillance and discovery with a focus on viral hemorrhagic fevers...
  31. pmc Novel borna virus in psittacine birds with proventricular dilatation disease
    Kirsi S Honkavuori
    Columbia University, New York, NY, USA
    Emerg Infect Dis 14:1883-6. 2008
    ..Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds...
  32. pmc NS1 protein secretion during the acute phase of West Nile virus infection
    Joanne Macdonald
    Jerome L and Dawn Greene Infectious Disease Laboratory, Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 W 168th St, Rm 1801, New York, NY 10032, USA
    J Virol 79:13924-33. 2005
    ..Moreover, the 4G4-ACE was found to be superior in performance to both the IgM and plaque assays during this time period, suggesting that NS1 is a viable early diagnostic marker of WNV infection...
  33. pmc Heart and skeletal muscle inflammation of farmed salmon is associated with infection with a novel reovirus
    Gustavo Palacios
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 5:e11487. 2010
    ....
  34. pmc Identifying hosts of families of viruses: a machine learning approach
    Anil Raj
    Department of Applied Physics and Applied Mathematics, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e27631. 2011
    ..Furthermore, the predictive motifs robustly selected by the learning algorithm are found to show strong host-specificity and occur in highly conserved regions of the viral proteome...
  35. pmc Diagnostic system for rapid and sensitive differential detection of pathogens
    Thomas Briese
    Columbia University, New York, NY 10032, USA
    Emerg Infect Dis 11:310-3. 2005
    ..We describe a diagnostic system for rapid, sensitive, multiplex discrimination of microbial gene sequences and report its application for detecting 22 respiratory pathogens in clinical samples...
  36. pmc Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis
    Alice Nemajerova
    Department of Pathology, State University of New York at Stony Brook, Stony Brook, NY, USA
    PLoS ONE 4:e7784. 2009
    ..Collectively, our data imply that tumor suppressive properties of p73 are highly dependent on cellular context, wherein p73 plays a major role in T cell development and neoplasia...
  37. doi request reprint Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats
    Haitao Lv
    Department of Medicine, Albert Einstein College of Medicine, 1301 Morris Park Avenue, Price Center Room 368, New York, New York 10461, USA
    Analyst 136:2260-9. 2011
    ..The changes in the levels of biomarker metabolites allowed the phenotypical determination of the metabolic perturbations induced by indomethacin in a time-dependent manner...
  38. ncbi request reprint Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses
    Kavitha Yaddanapudi
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY 10032, USA
    FASEB J 20:2519-30. 2006
    ..In contrast, only rhesus T cells were sensitive to REBOV peptides. These findings are consistent with the observation that REBOV is not pathogenic in humans and have implications for understanding the pathogenesis of filoviral HF...
  39. pmc A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model
    Kerstin Becker
    Department of Pathology, Stony Brook University, Stony Brook, New York, USA
    Cell Cycle 7:1205-13. 2008
    ..Our data suggest that changes in HAUSP modulate tumor growth and apoptotic sensitivity in vivo...
  40. pmc Molecular identification of enterovirus by analyzing a partial VP1 genomic region with different methods
    G Palacios
    Neurovirosis Division, Virology Department, National Institute for Infectious Disease, Dr Carlos G Malbran, Buenos Aires, Argentina
    J Clin Microbiol 40:182-92. 2002
    ..Finally, although phylogenetic inference is the most demanding method in terms of knowledge of the user, it remained the best option analyzed...
  41. pmc Molecular epidemiology of echovirus 30: temporal circulation and prevalence of single lineages
    G Palacios
    Neurovirosis Division, Virology Department, Instituto Nacional de Enfermedades Infecciosas ANLIS Dr Carlos G Malbran, Buenos Aires, Argentina
    J Virol 76:4940-9. 2002
    ..This pattern of evolution is clearly different from that of other enteroviruses. A single lineage at a time appears to be circulating worldwide. This behavior may be related to the epidemic activity of EV30...
  42. pmc Molecular identification of adenoviruses in clinical samples by analyzing a partial hexon genomic region
    I Casas
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 772 W 168th Street, Floor 18, New York, NY 10032, USA
    J Clin Microbiol 43:6176-82. 2005
    ..Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing...
  43. pmc Use of a short fragment of the C-terminal E gene for detection and characterization of two new lineages of dengue virus 1 in India
    C Domingo
    Laboratorio de Arbovirus y Enfermedades Víricas Importadas, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Carretera Majadahonda Pozuelo Km 2, Majadahonda 28220, Madrid, Spain
    J Clin Microbiol 44:1519-29. 2006
    ..We propose the use of this methodology as a tool for real-time epidemiological surveillance of dengue virus infections and their pathogenesis...