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Genomes and Genes | Gustavo PalaciosSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenzaGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA
PLoS ONE 4:e8540. 2009..Furthermore, no evidence was found for increased frequency of risk factors for H1N1pdm disease...
Microbe hunting in laboratory animal researchGustavo Palacio
Mailman School of Public Health, Columbia University, New York, NY 10032, USA
ILAR J 51:245-54. 2010..To illustrate the complexity of pursuing pathogen discovery research, we include examples from our own work that are intended to provide insights into the process that led to the selection of particular strategies...- Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South AfricaGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
J Gen Virol 91:1315-24. 2010..We propose MWV as a tentative novel species in the Lassa-lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics... - Characterization of the Candiru antigenic complex (Bunyaviridae: Phlebovirus), a highly diverse and reassorting group of viruses affecting humans in tropical AmericaGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th St, Rm 1709, New York, NY 10032, USA
J Virol 85:3811-20. 2011..This high rate of reassortment illustrates the inaccuracy of a classification system based solely on antigenic relationships... - Aguacate virus, a new antigenic complex of the genus Phlebovirus (family Bunyaviridae)Gustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
J Gen Virol 92:1445-53. 2011..collected in Central and South America. Aguacate virus appears to be a natural reassortant and serves as one more example of the high frequency of reassortment in this genus... - Enteroviruses as agents of emerging infectious diseasesG Palacios
Jerome L and Dawn Greene Infectious Disease Laboratory, Columbia University, New York, New York 10032, USA
J Neurovirol 11:424-33. 2005..These links between enterovirus infections and emerging diseases are reviewed... - Human metapneumovirus infection in wild mountain gorillas, RwandaGustavo Palacios
Center for Infection and Immunity, Columbia University, Rm 1709, 722 W 168th St, New York, NY 10032, USA
Emerg Infect Dis 17:711-3. 2011..Surveillance is needed to ensure survival of these critically endangered animals... - Molecular identification of mumps virus genotypes from clinical samples: standardized method of analysisG Palacios
Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 W 168th Street, Fl 18, New York, NY 10032, USA
J Clin Microbiol 43:1869-78. 2005..This PCR assay for characterization of mumps infections coupled to a web-based analytical program provides a rapid method for identification of known and novel strains... - Genetic analysis of Israel acute paralysis virus: distinct clusters are circulating in the United StatesG Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
J Virol 82:6209-17. 2008..Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence... - Rapid molecular strategy for orbivirus detection and characterizationGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Clin Microbiol 49:2314-7. 2011..Phylogenetic assignment is achieved by automated Web-based sequence analysis of amplification products... - Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus)Gustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
J Gen Virol 92:2558-65. 2011..Phylogenetic analysis revealed similarities between SSRV and orthoreoviruses of birds, bats and other mammals that suggests potential for interspecies transmission... - MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in New York State during 2004-2005Daryl Lamson
Clinical Virology Program, Wadsworth Center, New York State Department of Health, Albany, NY, USA
J Infect Dis 194:1398-402. 2006..In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management... - Genomic and antigenic characterization of Jos virusAna Valeria Bussetti
Center for Infection and Immunity and WHO Collaborating Centre for Diagnostics, Surveillance and Immunotherapeutics for Emerging Infectious and Zoonotic Diseases, Mailman School of Public Health, Columbia University, New York, NY, USA
J Gen Virol 93:293-8. 2012..Here, we report genetic, ultrastructural and serological evidence that JOSV is an orthomyxovirus distinct from but phylogenetically related to viruses of the genus Thogotovirus... 
A new arenavirus in a cluster of fatal transplant-associated diseasesGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
N Engl J Med 358:991-8. 2008..Culture, polymerase-chain-reaction (PCR) and serologic assays, and oligonucleotide microarray analysis for a wide range of infectious agents were not informative...- Greene SCPrimer: a rapid comprehensive tool for designing degenerate primers from multiple sequence alignmentsOmar J Jabado
Jerome L. and Dawn Greene Laboratory for Infectious Diseases, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Nucleic Acids Res 34:6605-11. 2006.... - Global distribution of novel rhinovirus genotypeThomas Briese
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Emerg Infect Dis 14:944-7. 2008..Molecular dating indicates that these viruses have been circulating for at least 250 years... - Nonparametric methods for the analysis of single-color pathogen microarraysOmar J Jabado
Center for Infection and Immunity Mailman School of Public Health Columbia University New York, NY, USA
BMC Bioinformatics 11:354. 2010..Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied... - Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarrayPhenix lan Quan
Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
J Clin Microbiol 45:2359-64. 2007..Twenty-one different respiratory virus species were accurately characterized, including a recently identified novel genetic clade of rhinovirus... - Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern AustraliaNazir Savji
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
J Gen Virol 92:1676-87. 2011..Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex... - Genetic detection and characterization of lujo virus, a new hemorrhagic Fever-associated arenavirus from southern AfricaThomas Briese
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America
PLoS Pathog 5:e1000455. 2009..LUJV is a novel, genetically distinct, highly pathogenic arenavirus... - Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern AfricaThomas Briese
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA
PLoS Pathog 5:e1000455. 2009..LUJV is a novel, genetically distinct, highly pathogenic arenavirus... - Astrovirus encephalitis in boy with X-linked agammaglobulinemiaPhenix lan Quan
Columbia University, New York, New York 10032, USA
Emerg Infect Dis 16:918-25. 2010..Our findings expand the spectrum of causative agents associated with encephalitis and highlight unbiased molecular technology as a valuable tool for differential diagnosis of unexplained disease... - Comprehensive viral oligonucleotide probe design using conserved protein regionsOmar J Jabado
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
Nucleic Acids Res 36:e3. 2008..In silico testing using an experimentally derived thermodynamic model indicated near complete coverage of the viral sequence database... - Rapid molecular strategy for filovirus detection and characterizationJunhui Zhai
Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Clin Microbiol 45:224-6. 2007..Phylogenetic assignment is achieved by automated web-based sequence analysis of amplification products... - Rapid sequence-based diagnosis of viral infectionPhenix lan Quan
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Antiviral Res 79:1-5. 2008..Here we review the current status of viral diagnostics and the utility of various sequence-based diagnostic platforms for applications in clinical microbiology, surveillance and pathogen discovery... - Diversity and distribution of hantaviruses in South AmericaCadhla Firth
Center for Infection and Immunity, Columbia University, New York, New York, USA
J Virol 86:13756-66. 2012.... - Severe acute respiratory syndrome coronavirus persistence in Vero cellsGustavo Palacios
Greene Infectious Disease Laboratory, Mailman School of Public Health and Department of Epidemiology, Columbia University, NY 10032, USA
Chin Med J (Engl) 118:451-9. 2005..Persistence is associated with selected mutations in the SARS-CoV genome. This model may provide insight into SARS-related lung pathology and mechanisms by which humans and animals can serve as reservoirs for infection... - MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic feverGustavo Palacios
Columbia University, New York, New York 10032, USA
Emerg Infect Dis 12:692-5. 2006..We describe a diagnostic system for rapid, multiplex polymerase chain reaction identification of 10 different causes of viral hemorrhagic fevers... - Novel borna virus in psittacine birds with proventricular dilatation diseaseKirsi S Honkavuori
Columbia University, New York, NY, USA
Emerg Infect Dis 14:1883-6. 2008..Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds... - Diagnostics and discovery in viral hemorrhagic feversW Ian Lipkin
Center for Infection and Immunity, Mailman School of Public Health of Columbia University, New York, New York, USA
Ann N Y Acad Sci 1171:E6-11. 2009..This chapter reviews recent progress in the field of pathogen surveillance and discovery with a focus on viral hemorrhagic fevers... - NS1 protein secretion during the acute phase of West Nile virus infectionJoanne Macdonald
Jerome L and Dawn Greene Infectious Disease Laboratory, Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 W 168th St, Rm 1801, New York, NY 10032, USA
J Virol 79:13924-33. 2005..Moreover, the 4G4-ACE was found to be superior in performance to both the IgM and plaque assays during this time period, suggesting that NS1 is a viable early diagnostic marker of WNV infection... - Panmicrobial oligonucleotide array for diagnosis of infectious diseasesGustavo Palacios
Columbia University, New York, New York 10032, USA
Emerg Infect Dis 13:73-81. 2007.... - Heart and skeletal muscle inflammation of farmed salmon is associated with infection with a novel reovirusGustavo Palacios
Center for Infection and Immunity, Columbia University, New York, New York, United States of America
PLoS ONE 5:e11487. 2010.... - Identifying hosts of families of viruses: a machine learning approachAnil Raj
Department of Applied Physics and Applied Mathematics, Columbia University, New York, New York, United States of America
PLoS ONE 6:e27631. 2011..Furthermore, the predictive motifs robustly selected by the learning algorithm are found to show strong host-specificity and occur in highly conserved regions of the viral proteome... - Diagnostic system for rapid and sensitive differential detection of pathogensThomas Briese
Columbia University, New York, NY 10032, USA
Emerg Infect Dis 11:310-3. 2005..We describe a diagnostic system for rapid, sensitive, multiplex discrimination of microbial gene sequences and report its application for detecting 22 respiratory pathogens in clinical samples... - Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesisAlice Nemajerova
Department of Pathology, State University of New York at Stony Brook, Stony Brook, NY, USA
PLoS ONE 4:e7784. 2009..Collectively, our data imply that tumor suppressive properties of p73 are highly dependent on cellular context, wherein p73 plays a major role in T cell development and neoplasia... - Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of ratsHaitao Lv
Department of Medicine, Albert Einstein College of Medicine, 1301 Morris Park Avenue, Price Center Room 368, New York, New York 10461, USA
Analyst 136:2260-9. 2011..The changes in the levels of biomarker metabolites allowed the phenotypical determination of the metabolic perturbations induced by indomethacin in a time-dependent manner... - Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg virusesKavitha Yaddanapudi
Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY 10032, USA
FASEB J 20:2519-30. 2006..In contrast, only rhesus T cells were sensitive to REBOV peptides. These findings are consistent with the observation that REBOV is not pathogenic in humans and have implications for understanding the pathogenesis of filoviral HF... - A role of HAUSP in tumor suppression in a human colon carcinoma xenograft modelKerstin Becker
Department of Pathology, Stony Brook University, Stony Brook, New York, USA
Cell Cycle 7:1205-13. 2008..Our data suggest that changes in HAUSP modulate tumor growth and apoptotic sensitivity in vivo... - Molecular identification of enterovirus by analyzing a partial VP1 genomic region with different methodsG Palacios
Neurovirosis Division, Virology Department, National Institute for Infectious Disease, Dr Carlos G Malbran, Buenos Aires, Argentina
J Clin Microbiol 40:182-92. 2002..Finally, although phylogenetic inference is the most demanding method in terms of knowledge of the user, it remained the best option analyzed... - Molecular epidemiology of echovirus 30: temporal circulation and prevalence of single lineagesG Palacios
Neurovirosis Division, Virology Department, Instituto Nacional de Enfermedades Infecciosas ANLIS Dr Carlos G Malbran, Buenos Aires, Argentina
J Virol 76:4940-9. 2002..This pattern of evolution is clearly different from that of other enteroviruses. A single lineage at a time appears to be circulating worldwide. This behavior may be related to the epidemic activity of EV30... - Molecular identification of adenoviruses in clinical samples by analyzing a partial hexon genomic regionI Casas
Jerome L. and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 772 W. 168th Street, Floor 18, New York, NY 10032, USA
J Clin Microbiol 43:6176-82. 2005..Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing... - Use of a short fragment of the C-terminal E gene for detection and characterization of two new lineages of dengue virus 1 in IndiaC Domingo
Laboratorio de Arbovirus y Enfermedades Víricas Importadas, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Carretera Majadahonda Pozuelo Km 2, Majadahonda 28220, Madrid, Spain
J Clin Microbiol 44:1519-29. 2006..We propose the use of this methodology as a tool for real-time epidemiological surveillance of dengue virus infections and their pathogenesis...