Deb Pal

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy
    Deb K Pal
    Department of Biostatistics, Mailman School of Public Health, and Columbia Genome Center, Columbia University and Clinical and Genetic Epidemiology Unit, New York State Psychiatric Institute, New York, 10032, USA
    Am J Hum Genet 73:261-70. 2003
  2. ncbi China begins long march to epilepsy control
    Deb K Pal
    Division of Statistical Genetics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Lancet Neurol 2:525. 2003
  3. ncbi Phenotypic features of familial febrile seizures: case-control study
    Deb K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, and Division of Statistical Genetics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Neurology 60:410-4. 2003
  4. ncbi Evaluating genetic heterogeneity in complex disorders
    Deb K Pal
    Department of Psychiatry, Joseph Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Hum Hered 53:216-26. 2002
  5. ncbi Predictors of parental adjustment to children's epilepsy in rural India
    D K Pal
    Neurosciences Unit, Institute of Child Health, University College London, UK
    Child Care Health Dev 28:295-300. 2002
  6. ncbi Help-seeking patterns for children with epilepsy in rural India: implications for service delivery
    Deb K Pal
    Neurosciences Unit, Institute of Child Health, University College London, England
    Epilepsia 43:904-11. 2002
  7. ncbi Is social support sometimes a mixed blessing?
    D K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Child Care Health Dev 31:261-3. 2005
  8. pmc Complex inheritance and parent-of-origin effect in juvenile myoclonic epilepsy
    Deb K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, Columbia University, NY 10032, USA
    Brain Dev 28:92-8. 2006
  9. pmc Evaluating candidate genes in common epilepsies and the nature of evidence
    Deb K Pal
    Epidemiology Division, Department of Psychiatry, Columbia University Medical Center, New York, New York 10032, USA
    Epilepsia 49:386-92. 2008
  10. ncbi Genetics of juvenile myoclonic epilepsy: faulty components and faulty wiring?
    Martina Durner
    Division of Statistical Genetics, Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York, USA
    Adv Neurol 95:245-54. 2005

Research Grants

  1. Genetics of Rolandic Epilepsy
    Deb Pal; Fiscal Year: 2007
  2. Genetics of Rolandic Epilepsy
    Deb Pal; Fiscal Year: 2007

Collaborators

Detail Information

Publications25

  1. pmc BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy
    Deb K Pal
    Department of Biostatistics, Mailman School of Public Health, and Columbia Genome Center, Columbia University and Clinical and Genetic Epidemiology Unit, New York State Psychiatric Institute, New York, 10032, USA
    Am J Hum Genet 73:261-70. 2003
    ....
  2. ncbi China begins long march to epilepsy control
    Deb K Pal
    Division of Statistical Genetics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Lancet Neurol 2:525. 2003
  3. ncbi Phenotypic features of familial febrile seizures: case-control study
    Deb K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, and Division of Statistical Genetics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Neurology 60:410-4. 2003
    ..To identify phenotypic features of febrile seizures that can be used to reduce heterogeneity and thereby increase power in linkage analysis...
  4. ncbi Evaluating genetic heterogeneity in complex disorders
    Deb K Pal
    Department of Psychiatry, Joseph Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Hum Hered 53:216-26. 2002
    ..In complex disorders, the assumptions of the Admixture test are violated. We therefore explore how the estimate of alpha relates to the true proportion of linked families with a complex disorder in a population or dataset...
  5. ncbi Predictors of parental adjustment to children's epilepsy in rural India
    D K Pal
    Neurosciences Unit, Institute of Child Health, University College London, UK
    Child Care Health Dev 28:295-300. 2002
    ..The objective of our study was to test the hypothesis that maternal satisfaction with social support, measured at the beginning of treatment, would predict parental adjustment to the child's epilepsy after 1 year of treatment...
  6. ncbi Help-seeking patterns for children with epilepsy in rural India: implications for service delivery
    Deb K Pal
    Neurosciences Unit, Institute of Child Health, University College London, England
    Epilepsia 43:904-11. 2002
    ....
  7. ncbi Is social support sometimes a mixed blessing?
    D K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Child Care Health Dev 31:261-3. 2005
    ..Child behavioural problems in epilepsy originate from a poorly understood interplay between intrinsic, family and social factors...
  8. pmc Complex inheritance and parent-of-origin effect in juvenile myoclonic epilepsy
    Deb K Pal
    Clinical and Genetic Epidemiology Unit, Department of Psychiatry, Columbia University, NY 10032, USA
    Brain Dev 28:92-8. 2006
    ..We investigated evidence for maternal inheritance, female excess and patterns of familial seizure risk in a well-characterized sample of JME families...
  9. pmc Evaluating candidate genes in common epilepsies and the nature of evidence
    Deb K Pal
    Epidemiology Division, Department of Psychiatry, Columbia University Medical Center, New York, New York 10032, USA
    Epilepsia 49:386-92. 2008
    ..We conclude that adopting the perspective of integrating coherent and consistent evidence from different experimental approaches is a more appropriate requirement for proceeding to functional studies...
  10. ncbi Genetics of juvenile myoclonic epilepsy: faulty components and faulty wiring?
    Martina Durner
    Division of Statistical Genetics, Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York, USA
    Adv Neurol 95:245-54. 2005
  11. ncbi Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India
    D K Pal
    Neurosciences Unit, University College London, UK
    Lancet 351:19-23. 1998
    ..We undertook a randomised comparison of phenobarbital and phenytoin to assess the acceptability and efficacy of phenobarbital as monotherapy for childhood epilepsy in rural India...
  12. ncbi Validation of a Bengali adaptation of the Conners' Parent Rating Scale (CPRS-48)
    D K Pal
    Neurosciences Unit, Institute of Child Health, University College London, Wolfson Centre, UK
    Br J Med Psychol 72:525-33. 1999
    ..This study in rural India aimed to validate a translated version of the CPRS-48 for use in a study of anti-epileptic drug side-effects...
  13. ncbi Case-control and qualitative study of attrition in a community epilepsy programme in rural India
    D K Pal
    Neurosciences Unit, Institute of Child Health, University College London Medical School, UK
    Seizure 9:119-23. 2000
    ..Very poor families without a male head or with long journey times are at high risk of dropout. People with severe impairments need appropriate integrated rehabilitation...
  14. pmc Neurocysticercosis and epilepsy in developing countries
    D K Pal
    Neurosciences Unit, Institute of Child Health, University College London, UK
    J Neurol Neurosurg Psychiatry 68:137-43. 2000
    ..Either approach requires detailed economic evaluation...
  15. ncbi Epilepsy control in the 21st century: leave no child behind
    Deb K Pal
    Epilepsia 44:273-5. 2003
  16. pmc An autosomal dominant genetically heterogeneous variant of rolandic epilepsy and speech disorder
    Steven L Kugler
    Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Epilepsia 49:1086-90. 2008
    ..No abnormalities were found by cytogenetic analysis. Linkage analysis excluded loci at 11p, 15q, 16p12, and Xq22 for related phenotypes, suggesting genetic heterogeneity...
  17. pmc High risk of reading disability and speech sound disorder in rolandic epilepsy families: case-control study
    Tara Clarke
    Department of Epidemiology, Mailman School of Public Health, New York, New York 10032, USA
    Epilepsia 48:2258-65. 2007
    ....
  18. pmc Autosomal dominant inheritance of centrotemporal sharp waves in rolandic epilepsy families
    Bhavna Bali
    Department of Epidemiology, Columbia University, New York, New York 10032, USA
    Epilepsia 48:2266-72. 2007
    ..Previous studies have varied considerably in methodology, especially in the control of bias and confounding. We aimed to test the hypothesis of autosomal dominant inheritance of CTS in a well-designed family segregation analysis study...
  19. pmc Is Rolandic epilepsy associated with abnormal findings on cranial MRI?
    Jerrold L Boxerman
    Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, USA
    Epilepsy Res 75:180-5. 2007
    ..87, 95% CI: 0.18-4.33 after adjusting for potential demographic and technical factors. We conclude that routine cranial MRI abnormalities are common in RE, but no more common than in controls, and not specific for RE...
  20. pmc The state of the art in the genetic analysis of the epilepsies
    David A Greenberg
    Division of Statistical Genetics, Mailman School of Public Health, Columbia University Medical Center, 122 West 168th Street, 6th Floor, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 7:320-8. 2007
    ....
  21. pmc Malic enzyme 2 may underlie susceptibility to adolescent-onset idiopathic generalized epilepsy
    David A Greenberg
    Division of Statistical Genetics, Department of Psychiatry, and Columbia University Genome Center, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Am J Hum Genet 76:139-46. 2005
    ..The results suggest that GABA synthesis disruption predisposes to common IGE and that clinical seizures are triggered when mutations at other genes, or perhaps other insults, are present...
  22. ncbi Social integration of children with epilepsy in rural India
    Deb K Pal
    Neurosciences Unit, Institute of Child Health, University College, London, UK
    Soc Sci Med 54:1867-74. 2002
    ..The assessment of remediable risk and protective factors in the family and community is an important practical area for research in community-based rehabilitation...
  23. doi Attention impairment in rolandic epilepsy: systematic review
    Peregrine Murphy Kavros
    Department of Epidemiology, Columbia University Medical Center, New York, New York, USA
    Epilepsia 49:1570-80. 2008
    ..Impairments in distributed attention systems may inform a disease model for RE, as well as direct interventions...
  24. ncbi Distinct phenotype of early childhood inflammatory bowel disease
    Thankam Paul
    Division of Pediatric Gastroenterology, Nutrition and Liver Disease, Hasbro Childrens Hospital, Brown Medical School, Providence, RI, USA
    J Clin Gastroenterol 40:583-6. 2006
    ..Our goals were to answer 2 questions: (1) Is the presentation of early-onset inflammatory bowel disease (IBD) similar to typical adolescent-onset IBD? (2) Is there variability in familial aggregation in childhood IBD?..
  25. ncbi Genetic influence on rolandic epilepsy
    Bhavna Bali
    Ann Neurol 57:464-5; author reply 465. 2005

Research Grants5

  1. Genetics of Rolandic Epilepsy
    Deb Pal; Fiscal Year: 2007
    ..Furthermore, genetic discoveries from this research will stimulate discoveries in related severe idiopathic focal childhood epilepsies and neurodevelopmental biology. ..
  2. Genetics of Rolandic Epilepsy
    Deb Pal; Fiscal Year: 2007
    ..Furthermore, genetic discoveries from this research will stimulate discoveries in related severe idiopathic focal childhood epilepsies and neurodevelopmental biology. ..