D C Paik

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm
    David C Paik
    Department of Ophthalmology and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Exp Mol Med 36:524-33. 2004
  2. pmc Initial studies using aliphatic beta-nitro alcohols for therapeutic corneal cross-linking
    David C Paik
    Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Invest Ophthalmol Vis Sci 50:1098-105. 2009
  3. doi request reprint Phlegmonous gastritis and group A streptococcal toxic shock syndrome in a patient following functional endoscopic sinus surgery
    David C Paik
    Department of Surgery, Christiana Care Health System, Christiana Hospital, Newark, DE, USA
    Surg Infect (Larchmt) 11:545-9. 2010
  4. ncbi request reprint The nitrite/collagen reaction: non-enzymatic nitration as a model system for age-related damage
    D C Paik
    Harkness Eye Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Connect Tissue Res 42:111-22. 2001
  5. pmc Aliphatic beta-nitroalcohols for therapeutic corneoscleral cross-linking: chemical mechanisms and higher order nitroalcohols
    David C Paik
    Department of Ophthalmology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Invest Ophthalmol Vis Sci 51:836-43. 2010
  6. ncbi request reprint Nitrite-induced cross-linking alters remodeling and mechanical properties of collagenous engineered tissues
    David C Paik
    Department of Ophthalmology, Columbia University, New York, New York 10032, USA
    Connect Tissue Res 47:163-76. 2006
  7. ncbi request reprint Short chain aliphatic beta-nitro alcohols for corneoscleral cross-linking: corneal endothelial toxicity studies
    David C Paik
    Dept of Ophthalmology, Columbia University, College of Physicians and Surgeons, 635 W 165th St, Rm 840, New York, NY 10032, USA
    J Refract Surg 24:S741-7. 2008
  8. doi request reprint Aliphatic beta-nitro alcohols for non-enzymatic collagen cross-linking of scleral tissue
    David C Paik
    Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Exp Eye Res 87:279-85. 2008
  9. ncbi request reprint The nitrite/elastin reaction: implications for in vivo degenerative effects
    D C Paik
    Department of Surgery, Columbia University, St Luke s Roosevelt Hospital Center, New York, USA
    Connect Tissue Res 36:241-51. 1997
  10. ncbi request reprint Oxindolealanine in age-related human cataracts
    Lilia A Rousseva
    Department of Ophthalmology, Columbia University, New York, NY 10032, USA
    Exp Eye Res 85:861-8. 2007

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm
    David C Paik
    Department of Ophthalmology and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Exp Mol Med 36:524-33. 2004
    ..The upregulation of av mRNA and the avb3 integrin in blood vessels surrounded by a matrix expressing tenascin, indicates that angiogenesis is an ongoing process in the mature aortic aneurysm...
  2. pmc Initial studies using aliphatic beta-nitro alcohols for therapeutic corneal cross-linking
    David C Paik
    Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Invest Ophthalmol Vis Sci 50:1098-105. 2009
    ..Thus, this study was undertaken to evaluate these agents as potential pharmacologic alternatives to UVAR...
  3. doi request reprint Phlegmonous gastritis and group A streptococcal toxic shock syndrome in a patient following functional endoscopic sinus surgery
    David C Paik
    Department of Surgery, Christiana Care Health System, Christiana Hospital, Newark, DE, USA
    Surg Infect (Larchmt) 11:545-9. 2010
    ..The etiology remains unclear, although Streptococcus species is isolated frequently. The optimum treatment has not been delineated clearly but likely involves a combination of antibiotics with or without surgical resection...
  4. ncbi request reprint The nitrite/collagen reaction: non-enzymatic nitration as a model system for age-related damage
    D C Paik
    Harkness Eye Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Connect Tissue Res 42:111-22. 2001
    ..Thus, we propose non-enzymatic nitration as an in vitro model system for human collagen age-related damage...
  5. pmc Aliphatic beta-nitroalcohols for therapeutic corneoscleral cross-linking: chemical mechanisms and higher order nitroalcohols
    David C Paik
    Department of Ophthalmology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Invest Ophthalmol Vis Sci 51:836-43. 2010
    ..The present study was performed to identify the specific chemistry involved under physiologic conditions, with the intent of identifying more effective agents...
  6. ncbi request reprint Nitrite-induced cross-linking alters remodeling and mechanical properties of collagenous engineered tissues
    David C Paik
    Department of Ophthalmology, Columbia University, New York, New York 10032, USA
    Connect Tissue Res 47:163-76. 2006
    ..Thus, we concluded that NEN reactions may contribute to alterations in the biomechanical properties of collagen-containing tissues consistent with the age-related functional decline observed in human disease...
  7. ncbi request reprint Short chain aliphatic beta-nitro alcohols for corneoscleral cross-linking: corneal endothelial toxicity studies
    David C Paik
    Dept of Ophthalmology, Columbia University, College of Physicians and Surgeons, 635 W 165th St, Rm 840, New York, NY 10032, USA
    J Refract Surg 24:S741-7. 2008
    ..The present study was conducted to determine the cytotoxic threshold for these agents in vitro and to draw comparisons to commonly used topical ophthalmic agents...
  8. doi request reprint Aliphatic beta-nitro alcohols for non-enzymatic collagen cross-linking of scleral tissue
    David C Paik
    Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Exp Eye Res 87:279-85. 2008
    ..Since beta-nitro alcohols are known to have reasonable toxicity profiles, these agents could find utility as pharmacologic cross-linking agents for scleral thinning disease...
  9. ncbi request reprint The nitrite/elastin reaction: implications for in vivo degenerative effects
    D C Paik
    Department of Surgery, Columbia University, St Luke s Roosevelt Hospital Center, New York, USA
    Connect Tissue Res 36:241-51. 1997
    ....
  10. ncbi request reprint Oxindolealanine in age-related human cataracts
    Lilia A Rousseva
    Department of Ophthalmology, Columbia University, New York, NY 10032, USA
    Exp Eye Res 85:861-8. 2007
    ..The results suggest that OIA levels are elevated in human cataractous lenses thus providing further evidence to implicate tryptophan oxidation in this process...
  11. pmc Consumption of cured meats and prospective risk of chronic obstructive pulmonary disease in women
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 87:1002-8. 2008
    ..Nitrites generate oxidative-nitrative stress and were shown in animal models to cause emphysema. Prospective epidemiologic data on cured meats and chronic obstructive pulmonary disease (COPD), however, are sparse...
  12. ncbi request reprint Nitrite-modified extracellular matrix proteins deleteriously affect retinal pigment epithelial cell function and viability: a comparison study with nonenzymatic glycation mechanisms
    Zhen Wang
    Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, USA
    Curr Eye Res 30:691-702. 2005
    ..As a comparison, retinal pigment epithelium (RPE) cell behavior on glycolaldehyde-modified matrices (GMM) was also studied...