E V Nunes

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Treatment of depression in patients with alcohol or other drug dependence: a meta-analysis
    Edward V Nunes
    Depression Evaluation Service, New York State Psychiatric Institute and Department of Psychiatry, Columbia University, New York 10032, USA
    JAMA 291:1887-96. 2004
  2. ncbi request reprint Treatment of depression in patients with opiate dependence
    Edward V Nunes
    New York State Psychiatric Institute, and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Biol Psychiatry 56:793-802. 2004
  3. ncbi request reprint Clinical and translational research: introduction to the special issue
    Edward V Nunes
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, USA
    Exp Clin Psychopharmacol 10:155-8. 2002
  4. ncbi request reprint Comorbidity of substance use with depression and other mental disorders: from Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to DSM-V
    Edward V Nunes
    New York State Psychiatric Institute and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA
    Addiction 101:89-96. 2006
  5. ncbi request reprint Treating depression in substance abusers
    Edward V Nunes
    New York State Psychiatric Institute, 1051 Riverside Drive Unit 51, New York, NY 10032, USA
    Curr Psychiatry Rep 8:363-70. 2006
  6. pmc Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: have we chosen the best designs?
    Edward V Nunes
    Columbia University Department of Psychiatry, New York State Psychiatric Institute, National Drug Abuse Clinical Trials Network, Long Island Node, New York, NY, USA
    J Subst Abuse Treat 38:S97-112. 2010
  7. ncbi request reprint Psychiatric disorders and impairment in the children of opiate addicts: prevalances and distribution by ethnicity
    E V Nunes
    Depression Evaluation Service, New York State Psychiatric Institute, NY 10032, USA
    Am J Addict 9:232-41. 2000
  8. ncbi request reprint Independent versus substance-induced major depressive disorder in substance-dependent patients: observational study of course during follow-up
    Edward V Nunes
    Department of Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute, NY, USA
    J Clin Psychiatry 67:1561-7. 2006
  9. ncbi request reprint Behavioral therapy to augment oral naltrexone for opioid dependence: a ceiling on effectiveness?
    Edward V Nunes
    New York State Psychiatric Institute, Division on Substance Abuse, New York, New York 10032, USA
    Am J Drug Alcohol Abuse 32:503-17. 2006
  10. pmc Baseline matters: the importance of covariation for baseline severity in the analysis of clinical trials
    Edward V Nunes
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, NY 10032, USA
    Am J Drug Alcohol Abuse 37:446-52. 2011

Detail Information

Publications71

  1. ncbi request reprint Treatment of depression in patients with alcohol or other drug dependence: a meta-analysis
    Edward V Nunes
    Depression Evaluation Service, New York State Psychiatric Institute and Department of Psychiatry, Columbia University, New York 10032, USA
    JAMA 291:1887-96. 2004
    ..Depression and substance abuse are common and costly disorders that frequently co-occur, but controversy about effective treatment for patients with both disorders persists...
  2. ncbi request reprint Treatment of depression in patients with opiate dependence
    Edward V Nunes
    New York State Psychiatric Institute, and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Biol Psychiatry 56:793-802. 2004
    ..Research is needed on such integrated models of care and treatment algorithms to determine their efficacy and cost effectiveness...
  3. ncbi request reprint Clinical and translational research: introduction to the special issue
    Edward V Nunes
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, USA
    Exp Clin Psychopharmacol 10:155-8. 2002
    ....
  4. ncbi request reprint Comorbidity of substance use with depression and other mental disorders: from Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to DSM-V
    Edward V Nunes
    New York State Psychiatric Institute and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA
    Addiction 101:89-96. 2006
    ..To arrive at recommendations for addressing co-occurring psychiatric and substance use disorders in the development of the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-V) criteria...
  5. ncbi request reprint Treating depression in substance abusers
    Edward V Nunes
    New York State Psychiatric Institute, 1051 Riverside Drive Unit 51, New York, NY 10032, USA
    Curr Psychiatry Rep 8:363-70. 2006
    ....
  6. pmc Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: have we chosen the best designs?
    Edward V Nunes
    Columbia University Department of Psychiatry, New York State Psychiatric Institute, National Drug Abuse Clinical Trials Network, Long Island Node, New York, NY, USA
    J Subst Abuse Treat 38:S97-112. 2010
    ..Based on this review, recommendations are generated to inform the design of future effectiveness trials on treatments for substance abuse, HIV risk, and other behavioral health problems...
  7. ncbi request reprint Psychiatric disorders and impairment in the children of opiate addicts: prevalances and distribution by ethnicity
    E V Nunes
    Depression Evaluation Service, New York State Psychiatric Institute, NY 10032, USA
    Am J Addict 9:232-41. 2000
    ..The results suggest children of patients in treatment for opiate dependence from diverse ethnic groups are at risk for psychopathology. Programs for early detection and intervention should be devised and evaluated...
  8. ncbi request reprint Independent versus substance-induced major depressive disorder in substance-dependent patients: observational study of course during follow-up
    Edward V Nunes
    Department of Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute, NY, USA
    J Clin Psychiatry 67:1561-7. 2006
    ..The authors examined whether baseline and past diagnoses of DSM-IV primary (independent) or substance-induced depression or other psychiatric syndromes predict 1-year course of depression in substance-dependent patients...
  9. ncbi request reprint Behavioral therapy to augment oral naltrexone for opioid dependence: a ceiling on effectiveness?
    Edward V Nunes
    New York State Psychiatric Institute, Division on Substance Abuse, New York, New York 10032, USA
    Am J Drug Alcohol Abuse 32:503-17. 2006
    ..Future research should consider combinations of behavioral methods with new long-acting injectable or implantable naltrexone formulations...
  10. pmc Baseline matters: the importance of covariation for baseline severity in the analysis of clinical trials
    Edward V Nunes
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, NY 10032, USA
    Am J Drug Alcohol Abuse 37:446-52. 2011
    ..Such trials are expensive and time-consuming to conduct, but the underlying effect sizes tend to be modest, and often findings are disappointing, failing to show evidence of treatment effects...
  11. ncbi request reprint Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial
    David McDowell
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Drug Alcohol Depend 80:209-21. 2005
    ..The aim of this study was to test the hypothesis that desipramine would be an effective treatment in cocaine abusers with current depressive disorders...
  12. ncbi request reprint Using buprenorphine to facilitate entry into residential therapeutic community rehabilitation
    Eric D Collins
    Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Subst Abuse Treat 32:167-75. 2007
    ..The findings suggest the potential for buprenorphine to serve as a bridge, improving the viability of long-term residential treatment for managing opioid dependence...
  13. ncbi request reprint Psychopathology in children of parents with opiate dependence and/or major depression
    E V Nunes
    Department of Genetic Epidemiology, New York State Psychiatric Institute, NY 10032, USA
    J Am Acad Child Adolesc Psychiatry 37:1142-51. 1998
    ..To evaluate psychiatric disorders and impairment in school-age and adolescent children of opiate-dependent patients...
  14. ncbi request reprint Anger and depressive states among treatment-seeking drug abusers: testing the psychopharmacological specificity hypothesis
    E Aharonovich
    Division on Substance Abuse Substance Treatment and Research Services, New York State Psychiatric Institute, New York City 10032, USA
    Am J Addict 10:327-34. 2001
    ..Data are discussed in terms of diagnosis and clinical treatment implications...
  15. ncbi request reprint Suicide risk in depressed methadone-maintained patients: associations with clinical and demographic characteristics
    Jordana Phillips
    University of Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Am J Addict 13:327-32. 2004
    ..When evaluating opiate-dependent patients with depressive disorders, these features should be considered in efforts to identify those at heightened risk for suicide and plan interventions...
  16. pmc Substance use, childhood sexual abuse, and sexual risk behavior among women in methadone treatment
    Lisa R Cohen
    Department of Psychiatry, Columbia University Medical Center, New York, New York, USA lc21302columbia edu
    Am J Drug Alcohol Abuse 35:305-10. 2009
    ..Substance use and a history of childhood sexual abuse (CSA) are risk factors for unprotected sex among women, yet questions remain as to how their combined influence may differentially affect sexual risk...
  17. pmc DSM-IV criteria-based clinical subtypes of cannabis use disorders: results from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC)
    Carlos Blanco
    New York State Psychiatric Institute, New York, NY 10032, USA
    Drug Alcohol Depend 96:136-44. 2008
    ..Future research should investigate whether there are differences in the course and treatment response of these clinical subtypes of cannabis use disorders, and the heterogeneity of other substance use disorders...
  18. pmc Comorbidity of generalized anxiety disorder and substance use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Analucia A Alegria
    New York State Psychiatric Institute, New York, USA
    J Clin Psychiatry 71:1187-95; quiz 1252-3. 2010
    ....
  19. ncbi request reprint The effect of sertraline on methadone plasma levels in methadone-maintenance patients
    S P Hamilton
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, NY 10032, USA
    Am J Addict 9:63-9. 2000
    ..Clinicians treating depressed or anxious methadone patients with second-generation antidepressants should monitor for clinical signs of increased or decreased methadone levels and consider monitoring serum methadone levels...
  20. ncbi request reprint Attentional bias towards cocaine-related stimuli: relationship to treatment-seeking for cocaine dependence
    Nehal P Vadhan
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, Columbia University New York, New York 10032, USA
    Am J Drug Alcohol Abuse 33:727-36. 2007
    ..The purpose of this study was to compare attentional bias towards cocaine-related verbal stimuli between treatment-seeking and nontreatment-seeking cocaine abusers...
  21. pmc Cognitive deficits in marijuana users: Effects on motivational enhancement therapy plus cognitive behavioral therapy treatment outcome
    Efrat Aharonovich
    Columbia University, Department of Psychiatry, College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA
    Drug Alcohol Depend 95:279-83. 2008
    ..If supported by further studies, the findings may help inform the development of interventions tailored for cognitively impaired marijuana-dependent patients...
  22. pmc A placebo-controlled trial of memantine for cocaine dependence with high-value voucher incentives during a pre-randomization lead-in period
    Adam Bisaga
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Drug Alcohol Depend 111:97-104. 2010
    ..Targeting the latter subgroup may advance medication development efforts...
  23. pmc OROS-methylphenidate or placebo for adult smokers with attention deficit hyperactivity disorder: racial/ethnic differences
    Lirio S Covey
    New York State Psychiatric Institute, Columbia University Medical Center, 1051 Riverside Drive, New York, NY 10032, United States
    Drug Alcohol Depend 110:156-9. 2010
    ..To explore racial/ethnic difference in OROS-methylphenidate (OMPH) efficacy when added to nicotine patch and counseling for treating nicotine dependence among smokers with attention deficit hyperactivity disorder (ADHD)...
  24. ncbi request reprint Early abstinence in cocaine dependence: influence of comorbid major depression
    Eric Rubin
    Division on Substance Abuse, Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, New York 10032, USA
    Am J Addict 16:283-90. 2007
    ..By Day 3, BDI scores improved for both CD and CD + MDD groups. The mood response to cocaine cessation among CD + MDD individuals resembled that of CD participants, contrary to some expectations...
  25. doi request reprint Dextromethorphan and quinidine combination for heroin detoxification
    Evaristo Akerele
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Am J Addict 17:176-80. 2008
    ..Future studies should examine dextromethorphan as an adjunct to other anti-withdrawal medications and focus more on the relationship between dextrorphan levels and withdrawal suppression...
  26. ncbi request reprint Generalizability of clinical trial results for major depression to community samples: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Carlos Blanco
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 69:1276-80. 2008
    ..The goal of this study was to assess the proportion of community-dwelling adults with major depressive episode (MDE) who would meet eligibility criteria for a traditional efficacy trial in patients with MDE...
  27. pmc Generalizability of clinical trials for alcohol dependence to community samples
    Carlos Blanco
    New York State Psychiatric Institute Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Box 69, New York, NY 10032, United States
    Drug Alcohol Depend 98:123-8. 2008
    ..Clinical trials should carefully evaluate the effects of the selected eligibility criteria on the generalizability of their results...
  28. pmc Effectiveness of HIV/STD sexual risk reduction groups for women in substance abuse treatment programs: results of NIDA Clinical Trials Network Trial
    Susan Tross
    Department of Psychiatry, HIV Center for Clinical and Behavioral Studies, Columbia University Medical Center, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 48:581-9. 2008
    ..Because drug-involved women are among the fastest growing groups with AIDS, sexual risk reduction intervention for them is a public health imperative...
  29. pmc Do treatment improvements in PTSD severity affect substance use outcomes? A secondary analysis from a randomized clinical trial in NIDA's Clinical Trials Network
    Denise A Hien
    City College of New York, North Academic Campus, 160 Convent Ave, New York, NY 10030, USA
    Am J Psychiatry 167:95-101. 2010
    ..The purpose of the analysis was to examine the temporal course of improvement in symptoms of posttraumatic stress disorder (PTSD) and substance use disorder among women in outpatient substance abuse treatment...
  30. pmc Multisite randomized trial of behavioral interventions for women with co-occurring PTSD and substance use disorders
    Denise A Hien
    Department of Psychology, City University of New York, City College of New York, New York, NY 10030, USA
    J Consult Clin Psychol 77:607-19. 2009
    ....
  31. pmc Relationship power and sexual risk among women in community-based substance abuse treatment
    Aimee N C Campbell
    Substance Abuse Division, New York State Psychiatric Institute, New York, NY 10032, USA
    J Urban Health 86:951-64. 2009
    ..Possible explanations for these findings are discussed, and future research directions for examining power constructs and developing interventions targeting relationship power among drug-involved women are suggested...
  32. pmc The impact of trauma-focused group therapy upon HIV sexual risk behaviors in the NIDA Clinical Trials Network "Women and trauma" multi-site study
    Denise A Hien
    Department of Psychology, City College of New York, City University of New York, North Academic Campus Room 8 131, 138th Street and Convent Avenue, New York, NY 10030, USA
    AIDS Behav 14:421-30. 2010
    ..High risk women with co-occurring PTSD and addiction may benefit from treatment addressing coping skills and trauma to reduce HIV risk...
  33. pmc Substance use and high risk sexual behaviors among women in psychosocial outpatient and methadone maintenance treatment programs
    Susan Tross
    Columbia University Medical Center, Department of Psychiatry, USA
    Am J Drug Alcohol Abuse 35:368-74. 2009
    ....
  34. pmc Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence
    Wilfrid Noel Raby
    Division on Substance Abuse, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Addict 18:301-8. 2009
    ..Experimental studies are needed to directly test the hypothesis that cannabinoid agonists exert a beneficial pharmacological effect on naltrexone maintenance and to understand the mechanism...
  35. pmc Betting on change: modeling transitional probabilities to guide therapy development for opioid dependence
    Kenneth M Carpenter
    Division on Substance Abuse, New York State Psychiatric Institute, USA
    Psychol Addict Behav 23:47-55. 2009
    ..PsycINFO Database Record (c) 2009 APA, all rights reserved)...
  36. doi request reprint Provigil (modafinil) plus cognitive behavioral therapy for methamphetamine use in HIV+ gay men: a pilot study
    Martin C McElhiney
    Therapeutics, New York State Psychiatric Institute, New York, New York, USA
    Am J Drug Alcohol Abuse 35:34-7. 2009
    ..To evaluate the efficacy of modafinil combined with cognitive behavioral therapy (CBT) for treatment of methamphetamine (MA) dependence among HIV+ gay men...
  37. pmc Cognition, commitment language, and behavioral change among cocaine-dependent patients
    Efrat Aharonovich
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Psychol Addict Behav 22:557-62. 2008
    ..Future clinical studies should further investigate the relations between cognition and commitment to change and their differential contributions to treatment processes and outcome...
  38. doi request reprint Developing therapies for depression in drug dependence: results of a stage 1 therapy study
    Kenneth M Carpenter
    New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, New York, New York, USA
    Am J Drug Alcohol Abuse 34:642-52. 2008
    ....
  39. pmc Effects of major depressive disorder and attention-deficit/hyperactivity disorder on the outcome of treatment for cocaine dependence
    Frances R Levin
    New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Subst Abuse Treat 34:80-9. 2008
    ....
  40. ncbi request reprint A randomized placebo-controlled trial of gabapentin for cocaine dependence
    Adam Bisaga
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Drug Alcohol Depend 81:267-74. 2006
    ..Gabapentin is an anticonvulsant medication that increases human brain GABA levels. We evaluated the safety and efficacy of gabapentin combined with relapse-prevention therapy in the treatment of cocaine-dependent individuals...
  41. ncbi request reprint Predictors of retention in naltrexone maintenance for opioid dependence: analysis of a stage I trial
    Maria A Sullivan
    Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA
    Am J Addict 15:150-9. 2006
    ....
  42. ncbi request reprint Behavioral naltrexone therapy: an integrated treatment for opiate dependence
    Jami L Rothenberg
    The New York State Psychiatric Institute, Division on Substance Abuse, Substance Treatment and Research Service, 1051 Riverside Drive, New York, NY 10032, USA
    J Subst Abuse Treat 23:351-60. 2002
    ..Thus, attrition continues to be a serious problem for naltrexone maintenance, although further efforts to develop interventions such as BNT are warranted...
  43. ncbi request reprint Temperament characteristics, as assessed by the tridimensional personality questionnaire, moderate the response to sertraline in depressed opiate-dependent methadone patients
    Wilfrid Noel Raby
    Substance Treatment and Research Service S T A R S, Division on Substance Abuse, Department of Psychiatry, New York State Psychiatric Institute and Columbia University, 1051 Riverside Drive, NYC, NY 10032, USA
    Drug Alcohol Depend 81:283-92. 2006
    ..These results suggest that temperament dimensions may be important for identifying substance dependent patients more likely to benefit from pharmacological interventions for comorbid depressive disorders...
  44. ncbi request reprint Cognitive deficits predict low treatment retention in cocaine dependent patients
    Efrat Aharonovich
    College of Physicians and Surgeons, Department of Psychiatry, Columbia University, Division on Substance Abuse, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 81:313-22. 2006
    ..Modified behavioral and pharmacologic interventions should be considered to target mild cognitive impairments to improve substance treatment outcome...
  45. ncbi request reprint Treatment of methadone-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placebo
    Frances R Levin
    New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
    Drug Alcohol Depend 81:137-48. 2006
    ..Taken together, sustained-release methylphenidate or sustained-release bupropion did not provide a clear advantage over placebo in reducing ADHD symptoms or additional cocaine use in methadone-maintained patients...
  46. ncbi request reprint Education and training in psychopharmacology
    Carlos Blanco
    Department of Psychiatry, Columbia University 1051 Riverside Dr, Box 69, New York, New York 10032, USA
    Acad Psychiatry 29:124-7. 2005
  47. ncbi request reprint Utility of lead-in period in cocaine dependence pharmacotherapy trials
    Adam Bisaga
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, NY, USA
    Drug Alcohol Depend 77:7-11. 2005
    ..Findings of this study suggest that route and level of cocaine use during lead-in be used as a covariate in models testing treatment effect...
  48. ncbi request reprint The effect of sertraline and environmental context on treating depression and illicit substance use among methadone maintained opiate dependent patients: a controlled clinical trial
    Kenneth M Carpenter
    Division on Substance Abuse, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, 1051 Riverside Drive, Box 120, New York, NY, 10032, USA
    Drug Alcohol Depend 74:123-34. 2004
    ..They also suggest future research should examine a pharmacological treatment that is combined with a behavioral intervention targeting the accessibility of reinforcement or reducing the impact of aversive environmental interactions...
  49. ncbi request reprint Severity of dependence and motivation for treatment: comparison of marijuana- and cocaine-dependent treatment seekers
    Frances R Levin
    New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
    J Addict Dis 25:33-41. 2006
    ....
  50. ncbi request reprint Verbal abilities as predictors of retention among adolescents in a therapeutic community
    Jeffrey J Wilson
    Department of Psychiatry, Division on Substance Abuse, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 66, New York, NY 10032, USA
    Child Psychiatry Hum Dev 36:393-401. 2006
    ..Remediation of verbal communication skills may be an overlooked aspect of the therapeutic process in treating adolescent substance abusers...
  51. ncbi request reprint Behavior therapy for depression in drug dependence (BTDD): results of a stage Ia therapy development pilot
    Kenneth M Carpenter
    Division on Substance Abuse, New York State Psychiatric Institute and Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Drug Alcohol Abuse 32:541-8. 2006
    ..There were no changes in opiate and cocaine use. BTDD may be a useful adjunct to methadone maintenance for treating comorbid depressive disorders...
  52. ncbi request reprint Neurological soft signs and disruptive behavior among children of opiate dependent parents
    Jeffrey J Wilson
    Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Child Psychiatry Hum Dev 34:19-34. 2003
    ....
  53. ncbi request reprint Management of relapse in naltrexone maintenance for heroin dependence
    Maria A Sullivan
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Drug Alcohol Depend 91:289-92. 2007
    ..Time retained in treatment was examined as a function of whether lapses to opioid use occurred while adherent to naltrexone (blocked use), or after having missed naltrexone doses (unblocked)...
  54. ncbi request reprint Concurrent cannabis use during treatment for comorbid ADHD and cocaine dependence: effects on outcome
    Efrat Aharonovich
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Am J Drug Alcohol Abuse 32:629-35. 2006
    ..02). This study is the first to examine concurrent cannabis use in cocaine dependent patients diagnosed with ADHD...
  55. ncbi request reprint Concurrent substance use and outcome in combined behavioral and naltrexone therapy for opiate dependence
    S H Church
    New York State Psychiatric Institute, Substance Treatment and Research Service, New York 10032, USA
    Am J Drug Alcohol Abuse 27:441-52. 2001
    ..Further research is needed to identify the optimal therapeutic stance toward other drug use during treatment for opiate dependence...
  56. ncbi request reprint Pergolide mesylate for cocaine abuse: a controlled preliminary trial
    F R Levin
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, NY 10032, USA
    Am J Addict 8:120-7. 1999
    ..Comparing an agent to both an active control and placebo group may better predict whether a promising new agent will have clinical utility compared to the standard open trial...
  57. ncbi request reprint Atypical features and treatment response in the National Institute of Mental Health Treatment of Depression Collaborative Research Program
    J W Stewart
    New York State Psychiatric Institute, New York, USA
    J Clin Psychopharmacol 18:429-34. 1998
    ..Failure to identify this subtype underestimates imipramine's benefit in the appropriately treated subgroup. Comparisons of other treatments with imipramine may be misleading if they do not account for diagnostic subtype...
  58. ncbi request reprint Divalproex treatment for youth with explosive temper and mood lability: a double-blind, placebo-controlled crossover design
    S J Donovan
    Department of Therapeutics, Division of Epidemiology of Brain Disorders, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Psychiatry 157:818-20. 2000
    ..The authors sought to replicate open-label findings showing that specific criteria for explosive temper and mood lability identify disruptive youth who improve while receiving the anticonvulsant divalproex sodium...
  59. ncbi request reprint Smoking cessation treatment in community-based substance abuse rehabilitation programs
    Malcolm S Reid
    Department of Psychiatry, New York University School of Medicine, New York, NY, USA
    J Subst Abuse Treat 35:68-77. 2008
    ..Substance abuse treatment programs should not hesitate to implement SC for established patients...
  60. ncbi request reprint Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action
    CHARLES P O'BRIEN
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104 6178, USA
    Biol Psychiatry 56:703-13. 2004
  61. ncbi request reprint "Outer-directed irritability": a distinct mood syndrome in explosive youth with a disruptive behavior disorder?
    Stephen J Donovan
    Department of Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 64:698-701. 2003
    ....
  62. ncbi request reprint Changes in the prevalence of non-medical prescription drug use and drug use disorders in the United States: 1991-1992 and 2001-2002
    Carlos Blanco
    Department of Epidemiology, Columbia University and the New York State Psychiatric Institute, New York, NY 10032, United States
    Drug Alcohol Depend 90:252-60. 2007
    ..To examine changes in the prevalence of non-medical prescription drug use and DSM-IV non-medical prescription abuse and dependence in the United States between 1991-1992 and 2001-2002...
  63. ncbi request reprint Therapeutic infusions of ketamine: do the psychoactive effects matter?
    E Dakwar
    New York State Psychiatric Institute, New York, NY, United States Columbia College of Physicians and Surgeons, New York, NY, United States Electronic address
    Drug Alcohol Depend 136:153-7. 2014
    ..This analysis evaluates the mystical-type effects of ketamine, which may have therapeutic potential according to prior research, and assesses whether these effects mediate improvements in dependence-related deficits, 24h postinfusion...
  64. ncbi request reprint Pathological gambling: addiction or compulsion?
    C Blanco
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
    Semin Clin Neuropsychiatry 6:167-76. 2001
    ..Improved understanding of the conceptualization of this disorder may help improve the quality of the treatments available...
  65. pmc Generalizability of clinical trials for cannabis dependence to community samples
    Mayumi Okuda
    New York State Psychiatric Institute Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Drug Alcohol Depend 111:177-81. 2010
    ..Clinical trials should carefully evaluate the effects of eligibility criteria on the generalizability of their results. Even in efficacy trials, stringent exclusionary criteria could limit the representativeness of study results...
  66. ncbi request reprint New-onset mania and psychosis following heroin detoxification and naltrexone maintenance
    Maria A Sullivan
    Am J Addict 14:486-7. 2005
  67. pmc Treatment programs in the National Drug Abuse Treatment Clinical Trials Network
    Dennis McCarty
    Oregon Health and Science University, 3181 SW Sam Jackson Park Road, CB669, Portland, OR 97239, USA
    Drug Alcohol Depend 92:200-7. 2008
    ..Conversely, programs with accreditation had less social model influence. The CTN is an ambitious effort to engage community-based treatment organizations into research and more fully integrate research and practice...
  68. pmc Direct care workers in the National Drug Abuse Treatment Clinical Trials Network: characteristics, opinions, and beliefs
    Dennis McCarty
    Department of Public Health and Preventive Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Psychiatr Serv 58:181-90. 2007
    ..Individuals with direct care responsibilities in 348 drug abuse treatment units were surveyed to obtain a description of the workforce and to assess support for evidence-based therapies...
  69. ncbi request reprint Providing live supervision via teleconferencing improves acquisition of motivational interviewing skills after workshop attendance
    Jennifer L Smith
    Montclair State University, Montclair, New Jersey, USA
    Am J Drug Alcohol Abuse 33:163-8. 2007
    ..Teleconferencing Supervision may help facilitate the proficient use of MI community clinicians following workshop instruction...
  70. ncbi request reprint Genomewide suggestive linkage of opioid dependence to chromosome 14q
    Herbert M Lachman
    Division of Basic Research, Department of Psychiatry and Behavioral Sciences, Albert Einstein College of MedicineBronx, NY 10461, USA
    Hum Mol Genet 16:1327-34. 2007
    ..05). Our linkage data suggest specific chromosomal loci for future fine-mapping genetic analysis and support the hypothesis that ethnic and gender specific genes underlie addiction susceptibility...
  71. pmc Organizational Readiness for Change and opinions toward treatment innovations
    Bret E Fuller
    Oregon Health and Science University, Portland, OR 97239, USA
    J Subst Abuse Treat 33:183-92. 2007
    ..The analysis provides evidence of the ORC's utility in assessing agency strengths and needs during the implementation of evidence-based practices...

Research Grants29

  1. BEHAVIORAL THERAPY FOR DEPRESSION IN DRUG DEPENDENCE
    Edward Nunes; Fiscal Year: 1999
    ..3. To test the theory that an increase in response-contingent reinforcement will produce an improvement in depression and reduced drug use. ..
  2. MI Training: Live Supervision by Tele-Conference
    Edward Nunes; Fiscal Year: 2006
    ..It is hypothesized that counselors trained with TCS-MI will achieve superior MI skills, as measured by the Motivational Interview Skill Coding (MISC) system, compared to controls. ..
  3. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2006
    ....
  4. Drug Abuse Treatment Development and Research Mentoring
    Edward Nunes; Fiscal Year: 2007
    ..The ultimate goals are to improve the treatment of drug dependent patients through clinical research and to help foster the next generation of clinician-researchers. ..
  5. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Maria Sullivan; Fiscal Year: 2007
    ....
  6. Clinical Trials Network: Long Island Regional Node
    Edward Nunes; Fiscal Year: 2007
    ..We will also continue to encourage and seek outside funding for studies conducted on the CTN platform. ..
  7. CU PARTNERS: NY/LONG ISLAND REGIONAL NODE
    Edward Nunes; Fiscal Year: 2007
    ..abstract_text> ..
  8. Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment Site
    Edward V Nunes; Fiscal Year: 2010
    ..The data from this study can also be used by the FDA to evaluate the benefits of this treatment that could improve the lives of patients suffering from opioid addiction. ..
  9. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2004
    ....
  10. DRUG ABUSE PHARMACOTHERAPY: METHODOLOGIC INITIATIVES
    Edward Nunes; Fiscal Year: 2005
    ..The applicant will continue to pursue a training plan focused on methodology and statistics of clinical trials, behavioral interventions, and the responsible conduct of research. ..
  11. MI Training: Live Supervision by Tele-Conference
    Edward Nunes; Fiscal Year: 2005
    ..It is hypothesized that counselors trained with TCS-MI will achieve superior MI skills, as measured by the Motivational Interview Skill Coding (MISC) system, compared to controls. ..
  12. BEHAVIORAL THERAPY FOR DEPRESSION IN DRUG DEPENDENCE
    Edward Nunes; Fiscal Year: 2000
    ..3. To test the theory that an increase in response-contingent reinforcement will produce an improvement in depression and reduced drug use. ..
  13. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2000
    ....
  14. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2001
    ....
  15. BEHAVIORAL THERAPY FOR DEPRESSION IN DRUG DEPENDENCE
    Edward Nunes; Fiscal Year: 2001
    ..3. To test the theory that an increase in response-contingent reinforcement will produce an improvement in depression and reduced drug use. ..
  16. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2001
    ....
  17. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2002
    ....
  18. BEHAVIORAL THERAPY FOR DEPRESSION IN DRUG DEPENDENCE
    Edward Nunes; Fiscal Year: 2002
    ..3. To test the theory that an increase in response-contingent reinforcement will produce an improvement in depression and reduced drug use. ..
  19. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2003
    ....
  20. MI Training: Live Supervision by Tele-Conference
    Edward Nunes; Fiscal Year: 2003
    ..It is hypothesized that counselors trained with TCS-MI will achieve superior MI skills, as measured by the Motivational Interview Skill Coding (MISC) system, compared to controls. ..
  21. OPIATE DEPENDENCE: COMBINED NALTREXONE/BEHAVIOR THERAPY
    Edward Nunes; Fiscal Year: 2004
    ....
  22. MI Training: Live Supervision by Tele-Conference
    Edward Nunes; Fiscal Year: 2004
    ..It is hypothesized that counselors trained with TCS-MI will achieve superior MI skills, as measured by the Motivational Interview Skill Coding (MISC) system, compared to controls. ..
  23. CU PARTNERS: NY/LONG ISLAND REGIONAL NODE
    Edward Nunes; Fiscal Year: 2005
    ..abstract_text> ..
  24. Training Motivational Interviewing Using Live Supervision
    Edward V Nunes; Fiscal Year: 2010
    ..This could have considerable potential to promote the adoption of new treatments into real-world practice, improving the quality of the clinical workforce and the quality of care delivered in the substance abuse treatment system. ..