A I Neugut

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Reported residential pesticide use and breast cancer risk on Long Island, New York
    Susan L Teitelbaum
    Department of Community Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Am J Epidemiol 165:643-51. 2007
  2. pmc Predictors of survival after hepatic resection among patients with colorectal liver metastasis
    X Wang
    Department of Biomedical Informatics, College of Physicians and Surgeons, New York Presbyterian Hospital, Columbia University, New York, NY 10032, USA
    Br J Cancer 97:1606-12. 2007
  3. pmc Exposure to fogger trucks and breast cancer incidence in the Long Island Breast Cancer Study Project: a case-control study
    Alexandra J White
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    Environ Health 12:24. 2013
  4. pmc Racial disparities in posttraumatic stress after diagnosis of localized breast cancer: the BQUAL study
    Neomi Vin-Raviv
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Natl Cancer Inst 105:563-72. 2013
  5. pmc Noninitiation of adjuvant chemotherapy in women with localized breast cancer: the breast cancer quality of care study
    Alfred I Neugut
    Division of Medical Oncology, Columbia University Medical Center, 722 W 168th St, Room 725, New York, NY 10032, USA
    J Clin Oncol 30:3800-9. 2012
  6. pmc Non-initiation of adjuvant hormonal therapy in women with hormone receptor-positive breast cancer: The Breast Cancer Quality of Care Study (BQUAL)
    Alfred I Neugut
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Breast Cancer Res Treat 134:419-28. 2012
  7. pmc The Breast Cancer Quality of Care Study (BQUAL): a multi-center study to determine causes for noncompliance with breast cancer adjuvant therapy
    Alfred I Neugut
    Department of Medicine, and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, School of Public Health, Columbia University Medical Center, 722 W 168th Street, New York, NY 10032, USA
    Breast J 18:203-13. 2012
  8. pmc Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Breast Cancer Res 8:R71. 2006
  9. pmc Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
    Mary Beth Terry
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    BMC Cancer 3:29. 2003
  10. ncbi request reprint Duration of adjuvant chemotherapy for colon cancer and survival among the elderly
    Alfred I Neugut
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, New York, NY 10032, USA
    J Clin Oncol 24:2368-75. 2006

Research Grants

Collaborators

Detail Information

Publications110 found, 100 shown here

  1. ncbi request reprint Reported residential pesticide use and breast cancer risk on Long Island, New York
    Susan L Teitelbaum
    Department of Community Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA
    Am J Epidemiol 165:643-51. 2007
    ..This study is the first known to suggest that self-reported use of residential pesticides may increase breast cancer risk. Further investigation in other populations is necessary to confirm these findings...
  2. pmc Predictors of survival after hepatic resection among patients with colorectal liver metastasis
    X Wang
    Department of Biomedical Informatics, College of Physicians and Surgeons, New York Presbyterian Hospital, Columbia University, New York, NY 10032, USA
    Br J Cancer 97:1606-12. 2007
    ..A substantial subgroup of patients with CLM who undergo hepatectomy experiences long-term survival. High hospital procedure volume and use of 5FU-based or HAI-based chemotherapy after resection were associated with improved prognosis...
  3. pmc Exposure to fogger trucks and breast cancer incidence in the Long Island Breast Cancer Study Project: a case-control study
    Alexandra J White
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    Environ Health 12:24. 2013
    ..Self-reported acute exposure to a fogger truck, which sprayed DDT prior to 1972, was hypothesized to increase the risk of breast cancer, particularly among women exposed at a young age or diagnosed with ER+PR+ breast cancer...
  4. pmc Racial disparities in posttraumatic stress after diagnosis of localized breast cancer: the BQUAL study
    Neomi Vin-Raviv
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Natl Cancer Inst 105:563-72. 2013
    ..This study examines changes in PTSD symptoms in the first 6 months after diagnosis and assesses racial/ethnic differences in PTSD symptomatology over time...
  5. pmc Noninitiation of adjuvant chemotherapy in women with localized breast cancer: the breast cancer quality of care study
    Alfred I Neugut
    Division of Medical Oncology, Columbia University Medical Center, 722 W 168th St, Room 725, New York, NY 10032, USA
    J Clin Oncol 30:3800-9. 2012
    ..For some women, adjuvant chemotherapy for nonmetastatic breast cancer decreases recurrences and increases survival; however, patient-physician decisions regarding chemotherapy receipt can be influenced by medical and nonmedical factors...
  6. pmc Non-initiation of adjuvant hormonal therapy in women with hormone receptor-positive breast cancer: The Breast Cancer Quality of Care Study (BQUAL)
    Alfred I Neugut
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Breast Cancer Res Treat 134:419-28. 2012
    ..Educational interventions to women about the benefits of hormonal therapy may decrease negative beliefs and increase hormone therapy initiation...
  7. pmc The Breast Cancer Quality of Care Study (BQUAL): a multi-center study to determine causes for noncompliance with breast cancer adjuvant therapy
    Alfred I Neugut
    Department of Medicine, and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, School of Public Health, Columbia University Medical Center, 722 W 168th Street, New York, NY 10032, USA
    Breast J 18:203-13. 2012
    ..This information may be useful in planning interventions to improve quality of care...
  8. pmc Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Breast Cancer Res 8:R71. 2006
    ..926, COX-2 .5209, and COX-2 .8473) may reduce overall breast cancer risk or risk for subtypes of breast cancer by modulating the inflammatory response and may interact with aspirin or any NSAID use...
  9. pmc Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
    Mary Beth Terry
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    BMC Cancer 3:29. 2003
    ....
  10. ncbi request reprint Duration of adjuvant chemotherapy for colon cancer and survival among the elderly
    Alfred I Neugut
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, New York, NY 10032, USA
    J Clin Oncol 24:2368-75. 2006
    ..However, little is known about the predictors of, or the survival associated with, duration of chemotherapy in the community...
  11. ncbi request reprint Epidemiology of anaphylaxis in the United States
    Matthew J Matasar
    Department of Medicine, New York Presbyterian Hospital, PH 18 127, 630 West 168th Street, New York, NY 10032, USA
    Curr Allergy Asthma Rep 3:30-5. 2003
    ..However, current data suggest that there are approximately 1500 annual deaths from anaphylaxis, and between 2.8 million and 42.7 million Americans are at risk of experiencing an episode of anaphylaxis during their lives...
  12. ncbi request reprint Use of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: a population-based study
    Alfred I Neugut
    Department of Medicine, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Oncol 20:2643-50. 2002
    ..We investigated the use of these treatments for stages II and III rectal cancer among the elderly and the effectiveness of these treatments on a population-based scale...
  13. ncbi request reprint Preventive oncology--lessons from preventive cardiology
    Alfred I Neugut
    Department of Medicine and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, and Columbia University, New York Presbyterian Hospital, New York, NY 10032, USA
    Lancet 363:1004-5. 2004
  14. ncbi request reprint Leisure and occupational physical activity and risk of colorectal adenomatous polyps
    A I Neugut
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Int J Cancer 68:744-8. 1996
    ..No effects were observed for females. Thus, in this study, both leisure and occupational physical activity were associated with a reduced risk of incident and metachronous adenomas among men but not women...
  15. ncbi request reprint Anaphylaxis in the United States: an investigation into its epidemiology
    A I Neugut
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Room PH18 127, New York, NY 10032, USA
    Arch Intern Med 161:15-21. 2001
    ..Anaphylaxis is a severe, life-threatening allergic reaction that affects both children and adults in the United States. However, data regarding the incidence and prevalence of anaphylaxis and the number of deaths caused by it are limited...
  16. pmc Association between prescription co-payment amount and compliance with adjuvant hormonal therapy in women with early-stage breast cancer
    Alfred I Neugut
    Herbert Irving Comprehensive Cancer Center, College of Physiciansand Surgeons, Columbia University, New York, NY, USA
    J Clin Oncol 29:2534-42. 2011
    ..Noncompliance with adjuvant hormonal therapy among women with breast cancer is common. Little is known about the impact of financial factors, such as co-payments, on noncompliance...
  17. ncbi request reprint Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients
    V R Grann
    Herbert Irving Comprehensive Cancer Center of Columbia University, School of Public Health, New York, NY 10032, USA
    J Clin Oncol 16:979-85. 1998
    ..Many question whether they should have prophylactic surgical procedures, ie, bilateral mastectomy and/or oophorectomy...
  18. ncbi request reprint Risk factors for advanced colorectal adenomas: a pooled analysis
    Mary Beth Terry
    Department of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 11:622-9. 2002
    ....
  19. ncbi request reprint Variations in the use of chemotherapy for elderly patients with advanced ovarian cancer: a population-based study
    Vijaya Sundararajan
    Department of Epidemiology, Joseph L Mailman School of Public Health, College of Physicians and Surgeons, New York University, 630 W 168th St, New York, NY 10032, USA
    J Clin Oncol 20:173-8. 2002
    ..The purpose of this study is to assess the use of chemotherapy in elderly patients with advanced ovarian cancer...
  20. ncbi request reprint Variations in the use of adjuvant chemotherapy for node-positive colon cancer in the elderly: a population-based study
    V Sundararajan
    Division of Epidemiology, Joseph L. Mailman School of Public Health, PH-18-127, 630 West 168th Street, New York, NY 10032, USA
    Cancer J 7:213-8. 2001
    ..Efforts are needed to ensure that elderly and non-Hispanic black patients receive appropriate treatment...
  21. ncbi request reprint Breast biopsy and race/ethnicity among women without breast cancer
    Judith S Jacobson
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Detect Prev 30:129-33. 2006
    ....
  22. pmc B-vitamin intake, one-carbon metabolism, and survival in a population-based study of women with breast cancer
    Xinran Xu
    Department of Community and Preventive Medicine, Box 1043, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Cancer Epidemiol Biomarkers Prev 17:2109-16. 2008
    ..Our results indicate that one-carbon metabolism may be an important pathway that could be targeted to improve breast cancer survival...
  23. doi request reprint Estrogen-biosynthesis gene CYP17 and its interactions with reproductive, hormonal and lifestyle factors in breast cancer risk: results from the Long Island Breast Cancer Study Project
    Yu Chen
    Department of Environmental Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Carcinogenesis 29:766-71. 2008
    ..In conclusion, the findings suggest that the CYP17 variant C allele may increase breast cancer risk in conjunction with long-term HRT use and high BMI in postmenopausal women...
  24. ncbi request reprint Chemotherapy and cardiotoxicity in older breast cancer patients: a population-based study
    John J Doyle
    Department of Medicine and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, 161 Ft Washington, Rm 1068, New York, NY 10032, USA
    J Clin Oncol 23:8597-605. 2005
    ..We studied the cardiac effects of chemotherapy in a population-based sample of breast cancer patients aged > or = 65 years with long-term follow-up...
  25. ncbi request reprint Increased incidence of colorectal adenomas in follow-up evaluation of patients with newly diagnosed hyperplastic polyps
    E H Huang
    Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Surg Endosc 15:646-8. 2001
    ..The aim of the current study was to determine whether a patient with an index finding of hyperplastic polyp on colonoscopy is at increased risk for adenomatous polyps...
  26. ncbi request reprint Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, New York, USA
    Cancer Res 64:7634-9. 2004
    ....
  27. ncbi request reprint Increased risk of squamous cell esophageal cancer after adjuvant radiation therapy for primary breast cancer
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Epidemiol 161:330-7. 2005
    ..This finding appears to be a function of the portals used for postmastectomy radiation therapy, which do not expose the lowest third of the esophagus, where adenocarcinomas commonly arise...
  28. ncbi request reprint Improving organochlorine biomarker models for cancer research
    Mary S Wolff
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cancer Epidemiol Biomarkers Prev 14:2224-36. 2005
    ..e., PCB) or long discontinued (i.e., DDE)...
  29. doi request reprint Obesity and screening PSA levels among men undergoing an annual physical exam
    Andrew Rundle
    Department of Epidemiology, Mailman School of Public Health, and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York 10032, USA
    Prostate 68:373-80. 2008
    ..Prior reports suggest that obesity is inversely associated with screening prostate-specific antigen (PSA) levels and may reduce screening sensitivity...
  30. ncbi request reprint Delay of adjuvant chemotherapy initiation following breast cancer surgery among elderly women
    Dawn L Hershman
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons Columbia University, 161 Ft Washington Room 1068, New York, NY 10032, USA
    Breast Cancer Res Treat 99:313-21. 2006
    ..However, the occurrence of delay in the delivery of adjuvant therapy and its impact on prognosis is not well understood...
  31. ncbi request reprint Within-stage racial differences in tumor size and number of positive lymph nodes in women with breast cancer
    Russell McBride
    Department of Epidemiology, Mailman School of Public Health, New York, New York, USA
    Cancer 110:1201-8. 2007
    ..It was hypothesized that differences in the tumor size and number of positive lymph nodes within each disease stage contribute to the survival disparity...
  32. ncbi request reprint Effect of prevention strategies on survival and quality-adjusted survival of women with BRCA1/2 mutations: an updated decision analysis
    Victor R Grann
    Herbert Irving Comprehensive Cancer Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th Street, New York, NY 10032, USA
    J Clin Oncol 20:2520-9. 2002
    ..This study updates findings regarding the effects of prophylactic surgery, chemoprevention, and surveillance on the survival and quality-adjusted survival of women who test positive for BRCA1/2 mutations...
  33. ncbi request reprint Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Cancer 97:1404-11. 2003
    ....
  34. ncbi request reprint Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients with node-positive colon cancer
    Vijaya Sundararajan
    Joseph L Mailman School of Public Health, The Herbert Irving Comprehensive Cancer Center, and College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Ann Intern Med 136:349-57. 2002
    ..Although this treatment became the standard in 1990 following a National Institutes of Health Consensus Conference, among those at least 65 years of age it is less likely to be offered to older or nonwhite patients...
  35. pmc Risk of colorectal adenomas and advanced neoplasia in Hispanic, black and white patients undergoing screening colonoscopy
    B Lebwohl
    Department of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY 10032, USA
    Aliment Pharmacol Ther 35:1467-73. 2012
    ..Racial and ethnic differences in the risk of premalignant colorectal neoplasia have not been extensively studied...
  36. pmc Risk of colorectal adenomas in patients with coeliac disease
    B Lebwohl
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Aliment Pharmacol Ther 32:1037-43. 2010
    ..Coeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer...
  37. ncbi request reprint Adjuvant therapy for rectal cancer in the elderly
    Seth M Cohen
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Drugs Aging 21:437-51. 2004
    ....
  38. doi request reprint Effect of breast cancer radiotherapy and cigarette smoking on risk of second primary lung cancer
    Elizabeth L Kaufman
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Clin Oncol 26:392-8. 2008
    ..Prior studies have found that postmastectomy radiotherapy (PMRT) for breast cancer (BC) increases the risk of lung cancer (LC). We explored the joint effects of cigarette smoking and PMRT on LC risk...
  39. ncbi request reprint Diabetes mellitus and the risk of prostate cancer
    David J Rosenberg
    Department of Medicine, Lenox Hill Hospital, 100 E 77th Street, New York, NY 10021, USA
    Cancer Invest 20:157-65. 2002
    ..Several studies have suggested a protective effect of diabetes mellitus on the risk of prostate cancer, though a study by our group has found an elevated risk of prostate cancer following ischemic heart disease...
  40. ncbi request reprint A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users
    Xinran Xu
    Departments of Community and Preventive Medicine and Epidemiology and Medicine, Columbia University, New York, NY, USA
    Am J Clin Nutr 85:1098-102. 2007
    ..Folic acid from multivitamins needs to be reduced by DHFR before it participates in cellular reactions...
  41. ncbi request reprint Benefits and costs of screening Ashkenazi Jewish women for BRCA1 and BRCA2
    V R Grann
    School of Public Health, and Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Oncol 17:494-500. 1999
    ..To determine the survival benefit and cost-effectiveness of screening Ashkenazi Jewish women for three specific BRCA1/2 gene mutations...
  42. ncbi request reprint Prostate-specific antigen, sex steroid hormones, and the insulin-like growth factor axis in U.S.-born, Jamaican, and Haitian black men: a pilot study
    Allen C Chen
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Urology 64:522-7. 2004
    ....
  43. ncbi request reprint OGG1 polymorphisms and breast cancer risk
    Pavel Rossner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Cancer Epidemiol Biomarkers Prev 15:811-5. 2006
    ..In addition, data on functionality of these polymorphisms are crucial to understand if these modest differences are important...
  44. pmc Choline metabolism and risk of breast cancer in a population-based study
    Xinran Xu
    Department of Community and Preventive Medicine, Mt Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    FASEB J 22:2045-52. 2008
    ..We observed a significant interaction between dietary betaine intake and the PEMT rs7926 polymorphism (P(interaction)=0.04). Our findings suggest that choline metabolism may play an important role in breast cancer etiology...
  45. ncbi request reprint Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 mutation
    Kristin Anderson
    Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Joseph L Mailman School of Public Health, Columbia University, and New York Presbyterian Hospital, New York, New York 10032, USA
    Ann Intern Med 144:397-406. 2006
    ..For BRCA1 or BRCA2 mutation carriers, decision analysis indicates that prophylactic surgery or chemoprevention leads to better survival than surveillance alone...
  46. ncbi request reprint Risk of perforation after colonoscopy and sigmoidoscopy: a population-based study
    Nicolle M Gatto
    Department of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, NY, USA
    J Natl Cancer Inst 95:230-6. 2003
    ..Although the risk of bowel perforation is often cited as a major factor in the choice between colonoscopy and sigmoidoscopy for colorectal screening, good estimates of the absolute and relative risks of perforation are lacking...
  47. ncbi request reprint Racial disparities in utilization of liver transplantation for hepatocellular carcinoma in the United States, 1998-2002
    Abby B Siegel
    Department of Medicine, Mailman School of Public Health, Columbia University, New York, New York, USA
    Am J Gastroenterol 103:120-7. 2008
    ..We assessed recent predictors of use of liver transplantation and its effect on survival for those with nonmetastatic HCC...
  48. ncbi request reprint Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study
    Xinran Xu
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Carcinogenesis 28:1504-9. 2007
    ..Although the pathway is a network of interrelated enzymes, redundancy exists; evaluating the rate-limiting enzyme and its interaction with environment and other genes within the same pathway is critical in assessing breast cancer risk...
  49. ncbi request reprint Increased risk of papillary thyroid cancer in celiac disease
    Laura Kent
    Department of Medicine, Columbia University College of Physicians and Surgeons, 161 Fort Washington Ave, Room 645, New York, 10032 New York, USA
    Dig Dis Sci 51:1875-7. 2006
    ..These patients were on a gluten-free diet. Only 1 had Hashimoto's thyroiditis, suggesting that mechanisms apart from autoimmune thyroiditis contribute to the increased risk of carcinoma of the thyroid in celiac disease...
  50. ncbi request reprint Reliability in the classification of advanced colorectal adenomas
    Mary Beth Terry
    Department of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 11:660-3. 2002
    ....
  51. ncbi request reprint Management of colorectal cancer in elderly patients: focus on the cost of chemotherapy
    Matthew J Matasar
    Department of Medicine, New College of Physicians and Surgeons, Columbia University, New York, USA
    Drugs Aging 21:113-33. 2004
    ..Nonetheless, as the effects of these novel agents upon both outcomes and costs continue to be defined, both curative and palliative treatment of colorectal cancer in the elderly patient will become more sophisticated and effective...
  52. ncbi request reprint Radiation therapy, cardiac risk factors, and cardiac toxicity in early-stage breast cancer patients
    John J Doyle
    Department of Epidemiology, Mailman School of Public, College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York, NY, USA
    Int J Radiat Oncol Biol Phys 68:82-93. 2007
    ..We studied the cardiac effects of RT and the impact of pre-existing cardiac risk factors (CRFs) in a population-based sample of older patients with breast cancer...
  53. ncbi request reprint Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk
    Mary Beth Terry
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    JAMA 291:2433-40. 2004
    ..Given the importance of estrogen in the pathogenesis of breast cancer, the ability of aspirin and other NSAIDs to protect against breast cancer could vary according to hormone receptor status...
  54. pmc Impact of socioeconomic status on extent of lymph node dissection for colon cancer
    Russell B McBride
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Cancer Epidemiol Biomarkers Prev 19:738-45. 2010
    ..We investigated whether this new standard of care was differentially adopted across racial and socioeconomic lines...
  55. ncbi request reprint One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancer
    Jia Chen
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USA
    Cancer Res 65:1606-14. 2005
    ..96) or total folate intake (OR, 1.71; 95% CI, 1.08-2.71). From a public heath perspective, it is important to identify risk factors, such as low B vitamin consumption, that may guide an effective prevention strategy against the disease...
  56. ncbi request reprint Inflammatory bowel disease in patients with celiac disease
    Alice Yang
    Department of Medicine, Pathology and Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Inflamm Bowel Dis 11:528-32. 2005
    ..We therefore studied the occurrence of these conditions in a cohort of patients with celiac disease seen at a referral center...
  57. ncbi request reprint Body size changes in relation to postmenopausal breast cancer among women on Long Island, New York
    Sybil M Eng
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10017, USA
    Am J Epidemiol 162:229-37. 2005
    ..55, 95% CI: 0.32, 0.96). These results add to the literature by focusing on the perimenopausal weight trajectory and support efforts urging women to avoid weight gain as they age...
  58. pmc Use of adjuvant 5-fluorouracil and radiation therapy after gastric cancer resection among the elderly and impact on survival
    Joshua Strauss
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Int J Radiat Oncol Biol Phys 76:1404-12. 2010
    ..We investigated the effectiveness of adjuvant chemoRT after gastric cancer resection in an elderly general population and its effects by stage...
  59. pmc Influence of health insurance, hospital factors and physician volume on receipt of immediate post-mastectomy reconstruction in women with invasive and non-invasive breast cancer
    D L Hershman
    Department of Medicine, Columbia University College of Physicians and Surgeons, Columbia University Medical Center, 161 Fort Washington Avenue, 10 1068, New York, NY 10032, USA
    Breast Cancer Res Treat 136:535-45. 2012
    ..Public policy should ensure that access to reconstructive surgery is universally available...
  60. ncbi request reprint Smoking and lung cancer risk in American and Japanese men: an international case-control study
    S D Stellman
    Division of Epidemiology, American Health Foundation, Valhalla, New York 10595, USA
    Cancer Epidemiol Biomarkers Prev 10:1193-9. 2001
    ....
  61. ncbi request reprint Outcomes of tamoxifen chemoprevention for breast cancer in very high-risk women: a cost-effectiveness analysis
    Dawn Hershman
    Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Joseph L Mailman School of Public Health, Columbia University, 630 West 168th St, New York, NY 10032, USA
    J Clin Oncol 20:9-16. 2002
    ..To estimate the effects on survival, quality-adjusted survival, and health care costs of using tamoxifen for primary prevention in subgroups of women at very high risk for breast cancer...
  62. pmc Patterns of use and risks associated with erythropoiesis-stimulating agents among Medicare patients with cancer
    Dawn L Hershman
    Columbia University Medical Center, 161 Fort Washington Ave, 10 1068, New York, NY 10032, USA
    J Natl Cancer Inst 101:1633-41. 2009
    ..Erythropoiesis-stimulating agents (erythropoietin and darbepoietin) have been approved to reduce the number of blood transfusions required during chemotherapy; however, concerns about the risks of venous thromboembolism and mortality exist...
  63. ncbi request reprint Racial disparities in treatment and survival of male breast cancer
    Katherine D Crew
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Oncol 25:1089-98. 2007
    ..We analyzed race and other predictors of treatment and survival among men with stage I-III breast cancer...
  64. pmc Cigarette smoking and risk of lung metastasis from esophageal cancer
    Julian A Abrams
    Department of Medicine, Columbia University Medical Center, 630 West 168th Street, Black Building 10 508, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 17:2707-13. 2008
    ..We investigated the association of cigarette smoking with lung metastasis in esophageal cancer...
  65. pmc Obesity and microvascular invasion in hepatocellular carcinoma
    Abby B Siegel
    Department of Medicine, Columbia University, New York, New York 10032, USA
    Cancer Invest 28:1063-9. 2010
    ..We hypothesized that hepatocellular carcinoma (HCC) patients with higher Body Mass Index (BMI) might have more microvascular invasion (MVI) in their tumors...
  66. doi request reprint Body composition, abdominal fat distribution, and prostate-specific antigen test results
    Andrew Rundle
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 730, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 18:331-6. 2009
    ..Under plasma volume dilution theory, PSA levels are inversely associated with both lean and fat mass and are independent of body fat distribution patterns...
  67. pmc Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean
    Victor R Grann
    Departments of Medicine, Epidemiology, and Health Policy, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Br J Haematol 143:288-93. 2008
    ..A better understanding of these associations may help to improve cancer outcomes among individuals of African ancestry...
  68. pmc The timing of cranial radiation in elderly patients with newly diagnosed glioblastoma multiforme
    Rose Lai
    Department of Neurology, The Neurological Institute, Columbia University, 710 West 168th Street, Room 204, New York, NY 10032, USA
    Neuro Oncol 12:190-8. 2010
    ..Although effort should be made to initiate radiotherapy as soon as possible after surgical resection/biopsy, a brief delay similar to that experienced by our cohort does not have a significant impact on survival...
  69. pmc Multiple genetic variants in telomere pathway genes and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 630 West 168th Street, P and S 19 418, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 19:219-28. 2010
    ..To explore the etiologic role of genetic variants in telomere pathway genes and breast cancer risk...
  70. pmc Surgeon characteristics and use of breast conservation surgery in women with early stage breast cancer
    Dawn L Hershman
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York, New York 10032, USA
    Ann Surg 249:828-33. 2009
    ..Aside from clinical factors, this decision may be associated with surgeon and patient characteristics. We investigated the effect of surgeon characteristics on the BCS rate...
  71. doi request reprint Breast cancer-related preferences among women with and without BRCA mutations
    Victor R Grann
    Herbert Irving Comprehensive Cancer Center, Department of Medicine, and Joseph L Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Breast Cancer Res Treat 119:177-84. 2010
    ..Our findings support the use of average-risk individuals' time trade-off preference ratings for health care policy development...
  72. ncbi request reprint Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke
    Beatrice Faraglia
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, New York, NY 10032, USA
    Carcinogenesis 24:719-25. 2003
    ..In this study, genetic polymorphisms did not significantly affect the formation of 4-ABP-DNA adducts in breast cancer cases, perhaps due to the small number of samples...
  73. ncbi request reprint Therapy-induced thoracic malignancies
    Lydia B Zablotska
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Clin Chest Med 25:217-24. 2004
    ..Potential signs and symptoms of thoracic malignancies should be approached with heightened vigilance in any patient who has a history of radiation exposure, regardless of how remote...
  74. ncbi request reprint Effectiveness of platinum-based chemotherapy among elderly patients with advanced ovarian cancer
    Dawn Hershman
    Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, 161 Fort Washington, New York, NY 10032, USA
    Gynecol Oncol 94:540-9. 2004
    ..We previously showed that only about half of women over the age of 65 years with this disease received platinum-based chemotherapy, and that the likelihood of receiving it decreases with age...
  75. ncbi request reprint Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:336-42. 2005
    ..Further understanding of the biological function of XRCC1 variants and their interactions with PAH-DNA adducts, antioxidants, and other genes in the pathway are needed...
  76. ncbi request reprint Hormone receptor status and survival in a population-based cohort of patients with breast carcinoma
    Victor R Grann
    Division of Medical Oncology, Department of Medicine, Columbia University Medical Center, New York, New York 10032, USA
    Cancer 103:2241-51. 2005
    ..The objective of this study was to assess hormone receptor status as an independent predictor of survival in a population-based cohort of women with breast carcinoma who were followed for up to 11 years...
  77. ncbi request reprint Patterns and outcomes of chemotherapy for elderly patients with stage II ovarian cancer: a population-based study
    Dawn Hershman
    The Department of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, New York, NY 10032, USA
    Gynecol Oncol 92:293-9. 2004
    ..The purpose of this study was to assess the patterns of use of chemotherapy in women with stage II ovarian cancer, and to compare the survival of treated and untreated patients aged 65+ years in a population-based sample...
  78. ncbi request reprint ADH3 genotype, alcohol intake and breast cancer risk
    Mary Beth Terry
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA, and Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Carcinogenesis 27:840-7. 2006
    ..9, 95 % CI=1.2-7.1; postmenopausal women OR=1.8, 95% CI=0.9-3.8). These population-based data support the hypothesis that fast metabolizers of alcohol have a higher risk of breast cancer risk, from alcohol intake than slow metabolizers...
  79. ncbi request reprint Incidences and trends of second cancers in female breast cancer patients: a fixed inception cohort-based analysis (United States)
    Guo Pei Yu
    Biostatistics and Epidemiology Service, The New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, USA
    Cancer Causes Control 17:411-20. 2006
    ..To determine incidences and time trends of second cancers among female breast cancer patients...
  80. ncbi request reprint Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk
    Pavel Rossner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 15:639-44. 2006
    ..In summary, our results suggest that urinary markers of lipid peroxidation and oxidative DNA damage may be associated with breast cancer risk...
  81. ncbi request reprint Incidence rates of acute promyelocytic leukemia among Hispanics, blacks, Asians, and non-Hispanic whites in the United States
    Matthew J Matasar
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Eur J Cancer Prev 15:367-70. 2006
    ....
  82. ncbi request reprint Estimating the effect of an intensive surveillance program on stage of breast carcinoma at diagnosis: a propensity score analysis
    N Mitra
    Division of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Cancer 91:1709-15. 2001
    ..The authors used propensity score adjustment to investigate the impact of intensive screening on stage of breast carcinoma at diagnosis in women who were at elevated risk for breast carcinoma...
  83. ncbi request reprint Risk of colorectal neoplasia associated with the adenomatous polyposis coli E1317Q variant
    M J Hall
    Departments of Medicine and Epidemiology, College of Physicians and Surgeons, and The Mailman School of Public Health, Columbia University, New York, NY, USA
    Ann Oncol 20:1517-21. 2009
    ..Using a case-control design, we investigated this relationship within a clinic-based cohort followed through the Integrated Cancer Prevention Center and the Tel-Aviv Sourasky Medical Center...
  84. ncbi request reprint Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer
    J S Jacobson
    Herbert Irving Comprehensive Cancer Center and Joseph L. Mailman School of Public Health, Columbia University, and Weill-Cornell Medical College, New York, NY 10032, USA
    J Clin Oncol 19:2739-45. 2001
    ..Our study illustrates the feasibility and value of standard clinical trial methodology in assessing the efficacy and safety of herbal agents...
  85. ncbi request reprint Risk of duodenal adenoma in celiac disease
    S Devi Rampertab
    Dept of Medicine and Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, USA
    Scand J Gastroenterol 38:831-3. 2003
    ..While the adenoma-carcinoma sequence appears to operate in the small bowel as in the large bowel, the risk of duodenal adenomas in celiac patients is unknown...
  86. ncbi request reprint Knowledge, beliefs, and barriers relevant to colorectal cancer screening in an urban population: a pilot study
    R L Wolf
    Department of Health and Behavior Studies, Teachers College, Columbia University, New York, New York, USA
    Fam Community Health 24:34-47. 2001
    ..Participants' willingness to engage in detailed telephone conversations about CRC and CRC screening was encouraging...
  87. ncbi request reprint Characteristics of adult celiac disease in the USA: results of a national survey
    S N Stavropoulos
    Department of Medicine, Columbia University College of Physicians and Surgeons, and School of Public Health, Columbia University, New York, New York, USA
    Am J Gastroenterol 96:126-31. 2001
    ..Improved quality of life after diagnosis is common. An increased risk of developing small intestine malignancies is present...
  88. ncbi request reprint Environmental tobacco smoke and breast cancer incidence
    Marilie D Gammon
    Department of Epidemiology, School of Public Health, University of North Carolina, CB 7435 McGavern Greenberg Hall, Chapel Hill, NC 27599 7435, USA
    Environ Res 96:176-85. 2004
    ..42 for ER+ PR+, 95% CI, 1.00, 2.00). Our data suggest that if there is an effect for ETS on breast cancer, that effect is restricted to selected subgroups of women, such as those with long-term exposure from a smoking spouse...
  89. ncbi request reprint Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
    Cancer Epidemiol Biomarkers Prev 13:1485-94. 2004
    ..Our results support an inverse association for fruit and vegetable intake among postmenopausal but not premenopausal breast cancer, which may be more pronounced among women with ER+ tumors...
  90. ncbi request reprint Obesity and awareness of obesity as risk factors for breast cancer in six ethnic groups
    Nathan S Consedine
    Intercultural Institute on Human Development and Aging, 191 Willoughby Street, Suite 1A, Brooklyn, NY 11201, USA
    Obes Res 12:1680-9. 2004
    ..To document BMI and knowledge regarding obesity as a risk factor for breast cancer among subpopulations of African-, Caribbean-, and European-American women and to consider the variables predicting obesity in these diverse groups...
  91. ncbi request reprint Dietary flavonoid intake and breast cancer risk among women on Long Island
    Brian N Fink
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Am J Epidemiol 165:514-23. 2007
    ..These results suggest that US women can consume sufficient levels of flavonoids to benefit from their potential chemopreventive effects...
  92. ncbi request reprint Active and passive cigarette smoke and breast cancer survival
    Sharon K Sagiv
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Ann Epidemiol 17:385-93. 2007
    ..The association between active and passive cigarette smoking before breast cancer diagnosis and survival was investigated among a cohort of invasive breast cancer cases (n = 1273) participating in a population-based case-control study...
  93. ncbi request reprint Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis
    Marilie D Gammon
    Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
    Arch Environ Health 59:640-9. 2004
    ..These data provide only modest support for an association between PAH-DNA adducts and breast cancer development...
  94. ncbi request reprint Fruits, vegetables, and micronutrient intake in relation to breast cancer survival
    Brian N Fink
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    Breast Cancer Res Treat 98:199-208. 2006
    ..To determine whether fruit, vegetable, and micronutrient intake 1 year prior to breast cancer diagnosis is associated with a reduction in the subsequent risk of all-cause or breast cancer-specific mortality...
  95. ncbi request reprint Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 27:1876-82. 2006
    ..These data indicate that GSTA1 genotypes related to reduced GSTA1 expression are associated with increased breast cancer primarily among women with lower consumption of cruciferous vegetables and among current smokers...
  96. ncbi request reprint Health belief model factors in mammography screening: testing for interactions among subpopulations of Caribbean women
    Nathan S Consedine
    Psychology Department, Long Island University, 1 University Plaza, Brooklyn, NY 11201, USA
    Ethn Dis 15:444-52. 2005
    ..To explore the implementation of health belief models in breast cancer screening and elucidate its potential to offer avenues for intervention among variables that may be easily amenable to change...
  97. ncbi request reprint Association of ampullary and colorectal malignancies
    Ananya Das
    Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Cancer 100:524-30. 2004
    ....
  98. ncbi request reprint Dietary flavonoid intake and breast cancer survival among women on Long Island
    Brian N Fink
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 16:2285-92. 2007
    ..However, the effects of flavonoids on survival are not known. In a population-based cohort of breast cancer patients, we investigated whether dietary flavonoid intake before diagnosis is associated with subsequent survival...
  99. ncbi request reprint Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts
    Marilie D Gammon
    Department of Epidemiology, University of North Carolina, School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
    Cancer Epidemiol Biomarkers Prev 11:677-85. 2002
    ..These data indicate that PAH-DNA adduct formation may influence breast cancer development, although the association does not appear to be dose dependent and may have a threshold effect...
  100. ncbi request reprint Weight gain prior to diagnosis and survival from breast cancer
    Rebecca J Cleveland
    Department of Epidemiology, University of North Carolina, CB 7435 McGavran Greenberg Hall, Chapel Hill, NC 27599 7435, USA
    Cancer Epidemiol Biomarkers Prev 16:1803-11. 2007
    ....
  101. ncbi request reprint Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hil, NC 27516, USA
    Breast Cancer Res Treat 99:235-40. 2006
    ....

Research Grants7

  1. COLORECTAL CANCER AND OTHER CANCERS OF THE GI TRACT
    Alfred Neugut; Fiscal Year: 2005
    ..abstract_text> ..
  2. Training Program in Cancer-Related Population Sciences
    Alfred Neugut; Fiscal Year: 2007
    ..Our R25 Training Program utilizes the rich research environment of the Herbert Irving Comprehensive Cancer Center, New York Presbyterian Hospital, Harlem Hospital, the Washington Heights/Harlem communities, and New York City. ..
  3. Cancer in Older Minority Populations
    Alfred Neugut; Fiscal Year: 2003
    ..Coordination of this P20 will be facilitated by the geographic proximity of the two institutions, their scientific strengths, and their commitment to similar programs. ..
  4. Cancer Epidemiology/Biostastistics/Environmental Health
    Alfred Neugut; Fiscal Year: 2006
    ..abstract_text> ..
  5. Cancer in Older Minority Populations Caribbean American*
    Alfred Neugut; Fiscal Year: 2007
    ..This partnership has a unique study population, a successful existing relationship, and an emphasis on population science research. ..