Jacqueline Montes

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Development and evaluation of a self-administered version of the ALSFRS-R
    J Montes
    Eleanor and Lou Gehrig MDA ALS Research Center, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032
    Neurology 67:1294-6. 2006
  2. doi request reprint Falls and spinal muscular atrophy: exploring cause and prevention
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, 180 Ft Washington Avenue, Fifth Floor, New York, New York 10032, USA
    Muscle Nerve 47:118-23. 2013
  3. doi request reprint Fatigue leads to gait changes in spinal muscular atrophy
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, 180 Ft Washington Avenue, Fifth Floor, New York, New York 10032, USA
    Muscle Nerve 43:485-8. 2011
  4. pmc Six-Minute Walk Test demonstrates motor fatigue in spinal muscular atrophy
    J Montes
    SMA Clinical Research Center, Department of Neurology, Columbia University, 180 Ft Washington Ave, 5th Floor, New York, NY 10032, USA
    Neurology 74:833-8. 2010
  5. ncbi request reprint The Timed Up and Go test: predicting falls in ALS
    Jacqueline Montes
    Department of Neurology, College of Physicians and Surgeons, The Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University, New York, NY 10032, USA
    Amyotroph Lateral Scler 8:292-5. 2007
  6. doi request reprint Clinical outcome measures in spinal muscular atrophy
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    J Child Neurol 24:968-78. 2009
  7. pmc Adiposity is increased among high-functioning, non-ambulatory patients with spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 3791, USA
    Neuromuscul Disord 20:448-52. 2010
  8. pmc Prospective cohort study of spinal muscular atrophy types 2 and 3
    Petra Kaufmann
    Department of Neurology, Columbia University, New York, USA
    Neurology 79:1889-97. 2012
  9. doi request reprint Thigh muscle volume measured by magnetic resonance imaging is stable over a 6-month interval in spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 3791, USA
    J Child Neurol 26:1252-9. 2011
  10. doi request reprint Muscle volume estimation by magnetic resonance imaging in spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, New York 10032 3791, USA
    J Child Neurol 26:309-17. 2011

Detail Information

Publications28

  1. ncbi request reprint Development and evaluation of a self-administered version of the ALSFRS-R
    J Montes
    Eleanor and Lou Gehrig MDA ALS Research Center, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032
    Neurology 67:1294-6. 2006
    ..The self-administered ALSFRS-R showed excellent reliability (intraclass correlation = 0.93, 95% CI: 088 to 0.96) and similar sensitivity to change over time vs the standard evaluator-administered ALSFRS-R...
  2. doi request reprint Falls and spinal muscular atrophy: exploring cause and prevention
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, 180 Ft Washington Avenue, Fifth Floor, New York, New York 10032, USA
    Muscle Nerve 47:118-23. 2013
    ..Weakness and gait variability are associated with falls in other neurological disorders, and fatigue is well documented in SMA. The relationship of weakness, fatigue, and gait variability to falls has never been investigated...
  3. doi request reprint Fatigue leads to gait changes in spinal muscular atrophy
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, 180 Ft Washington Avenue, Fifth Floor, New York, New York 10032, USA
    Muscle Nerve 43:485-8. 2011
    ..The 6-minute walk test (6MWT) is a reliable measure of fatigue in SMA patients. To further evaluate fatigue, we used quantitative gait analysis during the 6MWT...
  4. pmc Six-Minute Walk Test demonstrates motor fatigue in spinal muscular atrophy
    J Montes
    SMA Clinical Research Center, Department of Neurology, Columbia University, 180 Ft Washington Ave, 5th Floor, New York, NY 10032, USA
    Neurology 74:833-8. 2010
    ..The Six-Minute Walk Test (6MWT) is an objective, easily administered, and standardized evaluation of functional exercise capacity that has been proven reliable in other neurologic disorders and in children...
  5. ncbi request reprint The Timed Up and Go test: predicting falls in ALS
    Jacqueline Montes
    Department of Neurology, College of Physicians and Surgeons, The Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University, New York, NY 10032, USA
    Amyotroph Lateral Scler 8:292-5. 2007
    ..The TUG test can guide management of patients with ALS; a time of 14 s can be used to prompt the recommendation for mobility aids to prevent falls...
  6. doi request reprint Clinical outcome measures in spinal muscular atrophy
    Jacqueline Montes
    Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    J Child Neurol 24:968-78. 2009
    ..Following is an evidence-based review of available clinical outcome measures in spinal muscular atrophy...
  7. pmc Adiposity is increased among high-functioning, non-ambulatory patients with spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 3791, USA
    Neuromuscul Disord 20:448-52. 2010
    ....
  8. pmc Prospective cohort study of spinal muscular atrophy types 2 and 3
    Petra Kaufmann
    Department of Neurology, Columbia University, New York, USA
    Neurology 79:1889-97. 2012
    ..To characterize the natural history of spinal muscular atrophy type 2 and type 3 (SMA 2/3) beyond 1 year and to report data on clinical and biological outcomes for use in trial planning...
  9. doi request reprint Thigh muscle volume measured by magnetic resonance imaging is stable over a 6-month interval in spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 3791, USA
    J Child Neurol 26:1252-9. 2011
    ..Relative constancy of muscle volume estimation and correlation with established functional measures suggest a role for segmental magnetic resonance imaging as a biomarker of treatment effect in future therapeutic trials...
  10. doi request reprint Muscle volume estimation by magnetic resonance imaging in spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, New York 10032 3791, USA
    J Child Neurol 26:309-17. 2011
    ..14) than type 3. Reproducibility, tolerability, and strong correlation with clinical measures make magnetic resonance imaging a candidate biomarker for clinical research...
  11. doi request reprint Spinal muscular atrophy type III: trying to understand subtle functional change over time--a case report
    Sally Dunaway
    SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032, USA
    J Child Neurol 27:779-85. 2012
    ..However, she walked with assistance 2 years longer than expected. Our report highlights possible precipitating factors that could affect the natural history of spinal muscular atrophy type III...
  12. ncbi request reprint Outcome measures for early phase clinical trials
    Paul H Gordon
    Department of Neurology, The Eleanor and Lou Gehrig MDA ALS Research Center, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Amyotroph Lateral Scler 8:270-3. 2007
    ..The ALSFRS-R most strongly predicted survival and provided the most complete data, but large changes may be necessary before patients perceive treatment effects...
  13. doi request reprint Design and evaluation of a hybrid passive and active gravity neutral orthosis (GNO)
    Benjamin Koo
    Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, NY 10032 USA
    Conf Proc IEEE Eng Med Biol Soc 2009:1573-6. 2009
    ..The goal of this project is the development and evaluation of a mechanical arm orthosis to both encourage and assist functional arm movement while providing the user a sense of independence and control over one's own body...
  14. doi request reprint Bioelectrical impedance analysis can be a useful screen for excess adiposity in spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, New York, New York 10032 3791, USA
    J Child Neurol 25:1348-54. 2010
    ..Although insufficiently accurate for use as a research tool, bioelectrical impedance can have application as a well-tolerated, noninvasive, easily used screening tool for excess adiposity in patients with spinal muscular atrophy...
  15. doi request reprint Reliability of telephone administration of the PedsQL Generic Quality of Life Inventory and Neuromuscular Module in spinal muscular atrophy (SMA)
    Sally Dunaway
    SMA Clinical Research Center, Columbia University Medical Center, New York, NY, USA
    Neuromuscul Disord 20:162-5. 2010
    ..Notably, telephone administration is reliable in children as young as 8 years...
  16. doi request reprint Web-based data management for a phase II clinical trial in ALS
    Richard Buchsbaum
    Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Amyotroph Lateral Scler 10:374-7. 2009
    ..Given sufficient resources, a comprehensive web-based data management system can meet the need for clean, available data in clinical trials in ALS and similar diseases, and can contribute significantly to their efficient execution...
  17. doi request reprint An integrated motion capture system for evaluation of neuromuscular disease patients
    Viktor Gamarnik
    Biomedical Engineering Department, Columbia University, New York, NY 10027, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:218-21. 2009
    ..The highly interdisciplinary effort has led to significant progress toward the implementation of a new device, which is accurate, clinically relevant, and highly affordable...
  18. doi request reprint Observational study of spinal muscular atrophy type 2 and 3: functional outcomes over 1 year
    Petra Kaufmann
    Department of Neurology, Columbia University, 710 W 168th St, 2nd Floor, New York, NY 10032, USA
    Arch Neurol 68:779-86. 2011
    ..To characterize the short-term course of spinal muscular atrophy (SMA) in a genetically and clinically well-defined cohort of patients with SMA...
  19. doi request reprint A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS
    Paul H Gordon
    Department of Neurology, Columbia University, New York, USA
    Amyotroph Lateral Scler 9:212-22. 2008
    ..This phase II design was efficient, leading to treatment selection after just 60 patients, and can be used in other phase II trials to assess different agents...
  20. doi request reprint Weakness and fatigue in diverse neuromuscular diseases
    Jacqueline Montes
    1Department of Neurology, Columbia University Medical Center, New York, NY, USA
    J Child Neurol 28:1277-83. 2013
    ..In spinal muscular atrophy, weakness did not change, but fatigue increased significantly. These findings suggest independent mechanisms underlying weakness and fatigue in diverse neuromuscular conditions. ..
  21. doi request reprint Independent mobility after early introduction of a power wheelchair in spinal muscular atrophy
    Sally Dunaway
    Neurology Department, Columbia University Medical Center, New York, NY 10032, USA
    J Child Neurol 28:576-82. 2013
    ..9 months (range: 73-458 days). Introduction of early power mobility is feasible in spinal muscular atrophy patients under age 2 years and should be introduced in late infancy when children typically acquire locomotor skills...
  22. ncbi request reprint Quantitative objective markers for upper and lower motor neuron dysfunction in ALS
    H Mitsumoto
    Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University, New York, NY 10032, USA
    Neurology 68:1402-10. 2007
    ..To investigate the value of objective biomarkers for upper (UMN) and lower (LMN) motor neuron involvement in ALS...
  23. ncbi request reprint Randomized controlled phase II trial of glatiramer acetate in ALS
    P H Gordon
    Department of Neurology, Columbia University, NY, USA
    Neurology 66:1117-9. 2006
    ..01). Treated patients showed enhanced lymphocyte proliferation (p = 0.02). The safety profile and immune effects support conducting larger trials of dose selection and efficacy...
  24. ncbi request reprint A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS
    G Levy
    Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Neurology 66:660-3. 2006
    ..The combination of a small pool of patients at any given time with the availability of many potential neuroprotective agents to be tested in ALS requires efficient phase II trial designs...
  25. pmc Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
    Petra Kaufmann
    Department of Neurology, Clinical Coordinating Center, Columbia University, New York, NY 10032, USA
    Ann Neurol 66:235-44. 2009
    ..Our aims were to choose between two high doses of CoQ10 for ALS, and to determine if it merits testing in a Phase III clinical trial...
  26. pmc Increased fat mass and high incidence of overweight despite low body mass index in patients with spinal muscular atrophy
    Douglas M Sproule
    Division of Pediatric Neurosciences, Department of Neurology, SMA Clinical Research Center, Columbia University Medical Center, Harkness Pavilion, HP 514, 180 Fort Washington Avenue, New York, NY 10032 3791, USA
    Neuromuscul Disord 19:391-6. 2009
    ..Children with SMA have reduced lean and increased fat mass compared to healthy children. Obesity is a potentially important modifiable source of morbidity in SMA...
  27. ncbi request reprint Olfactory ensheathing glia injections in Beijing: misleading patients with ALS
    Sheena Chew
    Department of Neurology, Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University, New York, NY 10032, USA
    Amyotroph Lateral Scler 8:314-6. 2007
    ..Clinics that give experimental and potentially harmful treatments outside the construct of well-designed clinical trials put patients at risk and do a disservice to the ALS community...
  28. doi request reprint The role of exercise in amyotrophic lateral sclerosis
    Amy Chen
    Department of Neurology, Columbia University, 710 West 168th Street, 9th Floor, New York, NY 10032, USA
    Phys Med Rehabil Clin N Am 19:545-57, ix-x. 2008
    ..In this article, the authors review the literature on the role of exercise in patients who have ALS, and briefly compare what is known about exercise in other neuromuscular diseases...