Rachel L Miller

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children
    Arunima Kohli
    Department of Pediatric Allergy and Immunology, Stanford University, 269 Campus Drive, Stanford, CA, 94305, USA
    Clin Epigenetics 4:17. 2012
  2. pmc Reproducibility and intraindividual variation over days in buccal cell DNA methylation of two asthma genes, interferon γ (IFNγ) and inducible nitric oxide synthase (iNOS)
    Dz Torrone
    Division of Pulmonary, Allergy and Critical Care of Medicine, PH8E, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA
    Clin Epigenetics 4:3. 2012
  3. pmc Prenatal allergen and diesel exhaust exposure and their effects on allergy in adult offspring mice
    Lin Lin
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Allergy Asthma Clin Immunol 6:7. 2010
  4. pmc Polycyclic aromatic hydrocarbon metabolite levels and pediatric allergy and asthma in an inner-city cohort
    Rachel L Miller
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, New York, NY 10032, USA
    Pediatr Allergy Immunol 21:260-7. 2010
  5. pmc Prenatal maternal diet affects asthma risk in offspring
    Rachel L Miller
    Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Invest 118:3265-8. 2008
  6. pmc Environmental epigenetics and asthma: current concepts and call for studies
    Rachel L Miller
    PH8E, 630 W 168th Street, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Am J Respir Crit Care Med 177:567-73. 2008
  7. pmc Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort
    Rachel L Miller
    Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, PH8C, 630 168th Street, New York, NY 10032, USA
    Chest 126:1071-8. 2004
  8. pmc Cord blood versus age 5 mononuclear cell proliferation on IgE and asthma
    Carolyn Chang
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Clin Mol Allergy 8:11. 2010
  9. ncbi request reprint Prenatal exposure, maternal sensitization, and sensitization in utero to indoor allergens in an inner-city cohort
    R L Miller
    Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Respir Crit Care Med 164:995-1001. 2001
  10. pmc Anti-cockroach and anti-mouse IgE are associated with early wheeze and atopy in an inner-city birth cohort
    Kathleen M Donohue
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Allergy Clin Immunol 122:914-20. 2008

Research Grants

  1. INDUCIBLE DOMINANT NEGATIVE OF STAT 6 IN MEMORY IGE
    Rachel Miller; Fiscal Year: 2002
  2. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2005
  3. Prenatal diesel exposure and adult onset asthma
    Rachel Miller; Fiscal Year: 2006
  4. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2006
  5. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2007
  6. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2009

Collaborators

Detail Information

Publications55

  1. pmc Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children
    Arunima Kohli
    Department of Pediatric Allergy and Immunology, Stanford University, 269 Campus Drive, Stanford, CA, 94305, USA
    Clin Epigenetics 4:17. 2012
    ..abstract:..
  2. pmc Reproducibility and intraindividual variation over days in buccal cell DNA methylation of two asthma genes, interferon γ (IFNγ) and inducible nitric oxide synthase (iNOS)
    Dz Torrone
    Division of Pulmonary, Allergy and Critical Care of Medicine, PH8E, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA
    Clin Epigenetics 4:3. 2012
    ..19 to 0.56, P = 0.06 to 0.30). Our data reveal DNA methylation as a dynamic epigenetic mechanism that can be accessed safely and reproducibly in an inner city pediatric cohort using non-invasive buccal swabs and pyrosequencing technology...
  3. pmc Prenatal allergen and diesel exhaust exposure and their effects on allergy in adult offspring mice
    Lin Lin
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Allergy Asthma Clin Immunol 6:7. 2010
    ..fumigatus) allergen and diesel exhaust particles will be associated with altered IgE production, airway inflammation, airway hyperreactivity (AHR), and airway remodeling of adult offspring...
  4. pmc Polycyclic aromatic hydrocarbon metabolite levels and pediatric allergy and asthma in an inner-city cohort
    Rachel L Miller
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, New York, NY 10032, USA
    Pediatr Allergy Immunol 21:260-7. 2010
    ..Levels of PAH metabolites were not associated with respiratory symptoms. Measures of PAH metabolites suggest considerable exposure in an urban pediatric population, and possible associations with allergic sensitization to mouse...
  5. pmc Prenatal maternal diet affects asthma risk in offspring
    Rachel L Miller
    Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Invest 118:3265-8. 2008
    ..Site-specific differences in DNA methylation and reduced transcriptional activity were detected. If these findings are confirmed, a new paradigm for asthma pathogenesis may be emerging...
  6. pmc Environmental epigenetics and asthma: current concepts and call for studies
    Rachel L Miller
    PH8E, 630 W 168th Street, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Am J Respir Crit Care Med 177:567-73. 2008
    ..There is immense promise that the study of environmental epigenetics will help us understand a theoretically preventable environmental disease...
  7. pmc Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort
    Rachel L Miller
    Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, PH8C, 630 168th Street, New York, NY 10032, USA
    Chest 126:1071-8. 2004
    ....
  8. pmc Cord blood versus age 5 mononuclear cell proliferation on IgE and asthma
    Carolyn Chang
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Clin Mol Allergy 8:11. 2010
    ..Our objective was to compare indoor allergen-induced CBMC with age 5 peripheral blood mononuclear cell (PBMC) proliferation and determine which may be associated with age 5 allergic immune responses and asthma in an inner city cohort...
  9. ncbi request reprint Prenatal exposure, maternal sensitization, and sensitization in utero to indoor allergens in an inner-city cohort
    R L Miller
    Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Respir Crit Care Med 164:995-1001. 2001
    ....
  10. pmc Anti-cockroach and anti-mouse IgE are associated with early wheeze and atopy in an inner-city birth cohort
    Kathleen M Donohue
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Allergy Clin Immunol 122:914-20. 2008
    ....
  11. pmc Children's urinary phthalate metabolites and fractional exhaled nitric oxide in an urban cohort
    Allan C Just
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 722 W 168th Street, New York, NY 10032, USA
    Am J Respir Crit Care Med 186:830-7. 2012
    ..These results suggest that these two ubiquitous phthalates, previously shown to have substantial contributions from inhalation, are positively associated with airway inflammation in children...
  12. pmc Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort
    Allan C Just
    Columbia Center for Children s Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 120:1475-80. 2012
    ..Recent cross-sectional studies suggest a link between butylbenzyl phthalate (BBzP) in house dust and childhood eczema...
  13. pmc Early-life cockroach allergen and polycyclic aromatic hydrocarbon exposures predict cockroach sensitization among inner-city children
    Matthew S Perzanowski
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 131:886-93. 2013
    ..Furthermore, exposure to combustion byproducts, including polycyclic aromatic hydrocarbons (PAHs), can augment the development of allergic sensitization...
  14. pmc Domestic airborne black carbon and exhaled nitric oxide in children in NYC
    Alexandra G Cornell
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Expo Sci Environ Epidemiol 22:258-66. 2012
    ..020). The association between airborne BC in homes and both neighborhood asthma prevalence and FeNO suggest that further public health interventions on truck emissions standards and residual oil use are warranted...
  15. pmc Time trends of polycyclic aromatic hydrocarbon exposure in New York City from 2001 to 2012: assessed by repeat air and urine samples
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E 101, 630W 168 Street, New York, NY 10032, United States
    Environ Res 131:95-103. 2014
    ....
  16. pmc Childhood exposure to fine particulate matter and black carbon and the development of new wheeze between ages 5 and 7 in an urban prospective cohort
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E, 630 W 168 St New York, NY 10032, USA
    Environ Int 45:44-50. 2012
    ..We hypothesized that childhood exposure to PM(2.5) and the soot-BC component would be associated with the report of new wheeze and development of seroatopy in an inner city birth cohort...
  17. pmc Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort
    Matthew S Perzanowski
    Columbia Center for Children s Environmental Health CCCEH, New York, NY 10032, USA
    Thorax 65:118-23. 2010
    ....
  18. pmc Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children
    Molini M Patel
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, College of Physicians and Surgeons, 630 W 168th St, NY 10032, USA
    Environ Res 111:1222-9. 2011
    ..These findings may have broad implications for other urban populations that commonly have high asthma prevalence and exposure to a high density of traffic and stationary air pollution sources...
  19. pmc Ambient metals, elemental carbon, and wheeze and cough in New York City children through 24 months of age
    Molini M Patel
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University College of Physicians and Surgeons, 630 W 168th St, New York, NY 10032, USA
    Am J Respir Crit Care Med 180:1107-13. 2009
    ..The effects of exposure to specific components of ambient fine particulate matter (PM(2.5)), including metals and elemental carbon (EC), have not been fully characterized in young children...
  20. pmc Prenatal and postnatal bisphenol A exposure and asthma development among inner-city children
    Kathleen M Donohue
    Division of Pulmonary, Allergy and Critical Care, Columbia University School of Physicians and Surgeons, New York, NY, USA
    J Allergy Clin Immunol 131:736-42. 2013
    ..Bisphenol A (BPA) is used widely to manufacture food container linings. Mouse models suggest exposure to BPA might increase allergic inflammation...
  21. pmc Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children
    Maria Jose Rosa
    Columbia Center for Children s Environmental Health CCCEH, Columbia University, New York, New York 10032, USA
    Pediatr Pulmonol 46:83-91. 2011
    ..We hypothesized that the flow independent NO parameters would be associated differentially with wheeze and seroatopy...
  22. pmc Neighborhood differences in exposure and sensitization to cockroach, mouse, dust mite, cat, and dog allergens in New York City
    Omar Olmedo
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 128:284-292.e7. 2011
    ..Asthma prevalence varies widely among neighborhoods within New York City. Exposure to mouse and cockroach allergens has been suggested as a cause...
  23. pmc Cat ownership is a risk factor for the development of anti-cat IgE but not current wheeze at age 5 years in an inner-city cohort
    Matthew S Perzanowski
    Columbia Center for Children s Environmental Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 121:1047-52. 2008
    ..Cat ownership is inversely associated with atopy and asthma in some areas of the world, but the relevance of cat ownership to allergic disease in the inner city is less known...
  24. pmc Effects of winter birth season and prenatal cockroach and mouse allergen exposure on indoor allergen-specific cord blood mononuclear cell proliferation and cytokine production
    Cynthia Lendor
    Department of Medicine, Columbia University, New York, New York 10032, USA
    Ann Allergy Asthma Immunol 101:193-9. 2008
    ..Relationships among a particular birth season, maternal allergen exposure during the birth season, and childhood development of allergies to allergens in higher concentration during the birth season may be important...
  25. pmc Polycyclic aromatic hydrocarbon exposure, obesity and childhood asthma in an urban cohort
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E 101, 630 W 168th Street, New York, NY 10032, United States Electronic address
    Environ Res 128:35-41. 2014
    ..However, the interaction between these two on asthma among young urban children has not been studied previously...
  26. pmc Spatial and temporal trends of polycyclic aromatic hydrocarbons and other traffic-related airborne pollutants in New York City
    Rafael F Narváez
    Division of Pulmonary, Allergy and Critical Care of Medicine, College of Physicians and Surgeons, Columbia University, PH8E, 630 W 168th St, New York, New York 10032, USA
    Environ Sci Technol 42:7330-5. 2008
    ..By contrast PM2.5 levels were highly intercorrelated (values ranged from 0.725 to 0.922, p < 0.01). Further policy initiatives targeting traffic-related air pollutants may be needed for a greater impact on public health...
  27. pmc Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood
    Matthew S Perzanowski
    Columbia s Center for Children s Environmental Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 117:1082-9. 2006
    ..The relevance of this aspect of the hygiene hypothesis to US inner-city communities that have disproportionately high asthma prevalence has not been determined...
  28. pmc Prenatal exposure to pesticide ingredient piperonyl butoxide and childhood cough in an urban cohort
    Bian Liu
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168 Street, PH8E 101, New York, NY 10032, USA
    Environ Int 48:156-61. 2012
    ..Further, we explored the associations between these pesticide measures and wheeze, asthma, seroatopy, and fractional exhaled nitric oxide (FeNO)...
  29. pmc Exercise-induced wheeze, urgent medical visits, and neighborhood asthma prevalence
    Timothy R Mainardi
    Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Pediatrics 131:e127-35. 2013
    ..Among these asthmatics, we hypothesized that EIW would be associated with urgent medical visits and a child's neighborhood asthma prevalence...
  30. pmc Repeated exposure to polycyclic aromatic hydrocarbons and asthma: effect of seroatopy
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Ann Allergy Asthma Immunol 109:249-54. 2012
    ..Exposure to traffic-related air pollutants, including polycyclic aromatic hydrocarbons (PAHs), can induce asthma. However, the effects of early repeated PAH exposure over time on different asthma phenotypes have not been examined...
  31. pmc Using latent class growth analysis to identify childhood wheeze phenotypes in an urban birth cohort
    Qixuan Chen
    Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 W 168th St, New York, NY 10032, USA
    Ann Allergy Asthma Immunol 108:311-315.e1. 2012
    ....
  32. pmc Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and IgE production in vivo
    Jinming Liu
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Toxicol Sci 102:76-81. 2008
    ..This study is the first to demonstrate that inhaled environmental exposures influence methylation of Th genes in vivo, supporting a new paradigm in asthma pathogenesis...
  33. pmc Prenatal exposure to polycyclic aromatic hydrocarbons, environmental tobacco smoke and asthma
    Maria Jose Rosa
    Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, NY 10032, USA
    Respir Med 105:869-76. 2011
    ..Here, we hypothesized that children exposed to both prenatal PAH and ETS may be at greater risk of asthma and seroatopy at ages 5-6 years, after controlling for current pollution exposure...
  34. pmc Relationship between maternal demoralization, wheeze, and immunoglobulin E among inner-city children
    Marilyn Reyes
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, NY, USA
    Ann Allergy Asthma Immunol 107:42-49.e1. 2011
    ..However, this relationship has not been examined in inner-city African Americans and Hispanics, populations at high risk for asthma...
  35. pmc Urban tree canopy and asthma, wheeze, rhinitis, and allergic sensitization to tree pollen in a New York City birth cohort
    Gina S Lovasi
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA
    Environ Health Perspect 121:494-500, 500e1-6. 2013
    ..Several large-scale urban tree planting projects have sought to promote respiratory health, yet evidence linking tree cover to human health is limited...
  36. ncbi request reprint Prevalence of allergy symptoms and total IgE in a New York City cohort and their association with birth order
    Inge F Goldstein
    Columbia s Children s Center for Environmental Health CCCEH, Columbia University, New York, NY, USA
    Int Arch Allergy Immunol 137:249-57. 2005
    ..As part of an ongoing prospective birth cohort study, the prevalence of early phenotypes of asthma and/or allergy was compared with those reported in other studies, and the association with birth order was evaluated...
  37. pmc The challenge of preventing environmentally related disease in young children: community-based research in New York City
    Frederica P Perera
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Avenue, New York, NY 10032, USA
    Environ Health Perspect 110:197-204. 2002
    ..In turn, communities become better equipped to relay environmental health concerns to policy makers. In this paper we describe the center's research and its academic-community partnership and present some preliminary findings...
  38. pmc Assessment of benzo(a)pyrene-equivalent carcinogenicity and mutagenicity of residential indoor versus outdoor polycyclic aromatic hydrocarbons exposing young children in New York City
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, College of Physicians and Surgeons, Columbia University, PH8E, New York, NY 10032, USA
    Int J Environ Res Public Health 7:1889-900. 2010
    ..01). These findings suggest that at levels encountered in New York City air, especially during the heating season, residential exposure to PAH may pose an increased risk of cancer and mutation...
  39. doi request reprint Epigenetic regulation: the interface between prenatal and early-life exposure and asthma susceptibility
    Mariangels De Planell-Saguer
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York
    Environ Mol Mutagen 55:231-43. 2014
    ..As the field advances this may involve an individually tailored approach to the prevention, early detection, and treatment of disease based on the knowledge of an individual's epigenetic profile...
  40. pmc Epigenetics, asthma, and allergic diseases: a review of the latest advancements
    Stephanie Lovinsky-Desir
    Division of Pediatric Pulmonary, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Curr Allergy Asthma Rep 12:211-20. 2012
    ..The field has certainly advanced significantly in the past year...
  41. pmc Urinary naphthol metabolites and chromosomal aberrations in 5-year-old children
    Manuela A Orjuela
    Department of Pediatrics, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 21:1191-202. 2012
    ..Although prenatal (maternal) PAH exposure predicts chromosomal aberrations in cord blood, few studies have examined chromosomal aberrations in school-age children and none has examined their association with metabolites of specific PAHs...
  42. pmc Distribution and determinants of mouse allergen exposure in low-income New York City apartments
    Ginger L Chew
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Health Perspect 111:1348-51. 2003
    ..However, high levels of mouse allergen were also found in many homes where mothers reported never seeing mice...
  43. pmc Methods for detecting interactions between imprinted genes and environmental exposures using birth cohort designs with mother-offspring pairs
    Shuang Wang
    Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Hum Hered 71:196-208. 2011
    ....
  44. pmc Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure
    Marija Kundakovic
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Proc Natl Acad Sci U S A 110:9956-61. 2013
    ....
  45. pmc Antigen-specific immune responses to influenza vaccine in utero
    Deepa Rastogi
    Children s Hospital at Montefiore, Albert Einstein College of Medicine, New York, New York, USA
    J Clin Invest 117:1637-46. 2007
    ..These results suggest that B and T cell immune responses occur in the fetus following vaccination against influenza and have important implications for determining when immune responses to environmental exposures begin...
  46. pmc Polycyclic aromatic hydrocarbons impair function of β2-adrenergic receptors in airway epithelial and smooth muscle cells
    Phillip Factor
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Hospital, New York, NY 10003, USA
    Am J Respir Cell Mol Biol 45:1045-9. 2011
    ....
  47. ncbi request reprint Children's environmental health research--highlights from the Columbia Center for Children's Environmental Health
    Frederica Perera
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Ann N Y Acad Sci 1076:15-28. 2006
    ..This article summarizes the recent findings from the Center's projects in the context of current research in children's environmental health...
  48. ncbi request reprint Anaphylaxis in the United States: an investigation into its epidemiology
    A I Neugut
    Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Room PH18 127, New York, NY 10032, USA
    Arch Intern Med 161:15-21. 2001
    ..Anaphylaxis is a severe, life-threatening allergic reaction that affects both children and adults in the United States. However, data regarding the incidence and prevalence of anaphylaxis and the number of deaths caused by it are limited...
  49. pmc T-helper type 2 polarization among asthmatics during and following pregnancy
    D Rastogi
    Division of Pulmonary, Allergy, Critical Care, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Clin Exp Allergy 36:892-8. 2006
    ..While increased production of T helper cytokines has been reported to occur in both asthma and pregnancy, the effect of T-helper type 2 (Th2) polarization on asthma symptoms during pregnancy has not been well-characterized...
  50. ncbi request reprint Effect of Antiasthma Simplified Herbal Medicine Intervention on neutrophil predominant airway inflammation in a ragweed sensitized murine asthma model
    Kamal D Srivastava
    Division of Allergy and Immunology, Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, New York
    Ann Allergy Asthma Immunol 112:339-47.e1-2. 2014
    ..The effects of Antiasthma Simplified Herbal Medicine Intervention (ASHMI), a traditional Chinese medicine formula reported to be efficacious in asthmatic patients and murine asthma models, on neutrophil predominant asthma are unknown...
  51. pmc Air pollution and childhood asthma: recent advances and future directions
    Molini M Patel
    Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, NY 10032, USA
    Curr Opin Pediatr 21:235-42. 2009
    ....
  52. ncbi request reprint T-cell responses and hypersensitivity to influenza and egg antigens among adults with asthma immunized with the influenza vaccine
    Rachel L Miller
    Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, NY 10032, USA
    J Allergy Clin Immunol 112:606-8. 2003
    ..The American Lung Association Asthma Clinical Research Centers (ALA-ACRC) reported that the inactivated influenza vaccine is safe for patients with asthma and recommended its use to reduce the morbidity associated with infection...
  53. pmc A SOCS-1 promoter variant is associated with total serum IgE levels
    Justin Mostecki
    Department of Microbiology, Columbia University, New York, NY 10032, USA
    J Immunol 187:2794-802. 2011
    ..These data suggest that genetic variation in the SOCS-1 promoter may affect IgE production...
  54. ncbi request reprint Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group
    Phil Lieberman
    Division of Allergy Immunology, Department of Medicine, University of Tennessee College of Medicine, Germantown, Tennessee, USA
    Ann Allergy Asthma Immunol 97:596-602. 2006
    ..To improve understanding of the epidemiology of anaphylaxis...
  55. doi request reprint Modifications improve an offline exhaled nitric oxide collection device for use with young children
    Matthew S Perzanowski
    J Allergy Clin Immunol 122:213; author reply 214. 2008

Research Grants7

  1. INDUCIBLE DOMINANT NEGATIVE OF STAT 6 IN MEMORY IGE
    Rachel Miller; Fiscal Year: 2002
    ..Both the memory allergic response to antigenic stimulation and the polyclonal IgE response will be studied. In addition, the components of the memory response that are affected by Stat6 activity will be analyzed. (End of Abstract) ..
  2. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2005
    ..The primary goals are to determine whether diesel-related exposure can induce the development of allergy and/or asthma, and to identify its contribution relative to other urban exposures. ..
  3. Prenatal diesel exposure and adult onset asthma
    Rachel Miller; Fiscal Year: 2006
    ..Aim 4: Determine a) the differential gene expression following in utero diesel exposure, and b) whether differential gene expression following prenatal diesel exposure is associated with adult asthma. ..
  4. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2006
    ..The primary goals are to determine whether diesel-related exposure can induce the development of allergy and/or asthma, and to identify its contribution relative to other urban exposures. ..
  5. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2007
    ..The primary goals are to determine whether diesel-related exposure can induce the development of allergy and/or asthma, and to identify its contribution relative to other urban exposures. ..
  6. Urban Diesel Exposure and Inner City Asthma
    Rachel Miller; Fiscal Year: 2009
    ..The primary goals are to determine whether diesel-related exposure can induce the development of allergy and/or asthma, and to identify its contribution relative to other urban exposures. ..