MATE ISTVAN MILAK

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Effects of tryptophan depletion on the binding of [11C]-DASB to the serotonin transporter in baboons: response to acute serotonin deficiency
    Matthew S Milak
    Department of Neuroscience, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 57:102-6. 2005
  2. ncbi request reprint Neuroanatomic correlates of psychopathologic components of major depressive disorder
    Matthew S Milak
    Departments of Psychiatry and Radiology, Department of Neuroscience, NY State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Arch Gen Psychiatry 62:397-408. 2005
  3. pmc Modeling considerations for 11C-CUMI-101, an agonist radiotracer for imaging serotonin 1A receptor in vivo with PET
    Matthew S Milak
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nucl Med 49:587-96. 2008
  4. pmc Pretreatment regional brain glucose uptake in the midbrain on PET may predict remission from a major depressive episode after three months of treatment
    Matthew S Milak
    Department of Psychiatry, Columbia University, New York, NY, United States
    Psychiatry Res 173:63-70. 2009
  5. pmc In vivo serotonin-sensitive binding of [11C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer
    Matthew S Milak
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Cereb Blood Flow Metab 31:243-9. 2011
  6. doi request reprint In vivo quantification of human serotonin 1A receptor using 11C-CUMI-101, an agonist PET radiotracer
    Matthew S Milak
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Nucl Med 51:1892-900. 2010

Research Grants

Detail Information

Publications6

  1. ncbi request reprint Effects of tryptophan depletion on the binding of [11C]-DASB to the serotonin transporter in baboons: response to acute serotonin deficiency
    Matthew S Milak
    Department of Neuroscience, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 57:102-6. 2005
    ..A ligand insensitive to EC can provide a measure of SERT unaffected by levels of 5-HT. Alternatively, serotonin depletion could accelerate internalization of SERT and reduce binding...
  2. ncbi request reprint Neuroanatomic correlates of psychopathologic components of major depressive disorder
    Matthew S Milak
    Departments of Psychiatry and Radiology, Department of Neuroscience, NY State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Arch Gen Psychiatry 62:397-408. 2005
    ..The HDRS comprises distinct symptom clusters that may be associated with different patterns of regional brain glucose metabolism...
  3. pmc Modeling considerations for 11C-CUMI-101, an agonist radiotracer for imaging serotonin 1A receptor in vivo with PET
    Matthew S Milak
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Nucl Med 49:587-96. 2008
    ..Here we determine the optimal modeling parameters for 11C-MMP under its new name, 11C-CUMI-101, in Papio anubis...
  4. pmc Pretreatment regional brain glucose uptake in the midbrain on PET may predict remission from a major depressive episode after three months of treatment
    Matthew S Milak
    Department of Psychiatry, Columbia University, New York, NY, United States
    Psychiatry Res 173:63-70. 2009
    ..Prospective studies are needed to replicate these findings and determine whether outcome prediction is limited to a specific class of antidepressants...
  5. pmc In vivo serotonin-sensitive binding of [11C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer
    Matthew S Milak
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Cereb Blood Flow Metab 31:243-9. 2011
    ....
  6. doi request reprint In vivo quantification of human serotonin 1A receptor using 11C-CUMI-101, an agonist PET radiotracer
    Matthew S Milak
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Nucl Med 51:1892-900. 2010
    ..Here, we report the optimal modeling parameters of (11)C-CUMI-101 for human PET studies...

Research Grants2

  1. Characterization of a Novel 5-HT1A Receptor Agonist PET Ligand
    MATE MILAK; Fiscal Year: 2007
    ..Training research scientists in areas of translational research such as proposed here can accelerate the translation of new PET tracers to clinical research. ..