Research Topics
| John J MarianiSummaryAffiliation: Columbia University Country: USA Publications
Research Grants
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Detail Information
Publications
Psychostimulant treatment of cocaine dependenceJohn J Mariani
Division of Substance Abuse, New York State Psychiatric Institute, New York, NY 10032, USA
Psychiatr Clin North Am 35:425-39. 2012..Biases against using controlled substances as a treatment for cocaine dependence should be challenged, much in the way the use of agonist treatment transformed the treatment of opioid dependence despite initial resistance from the field...- Quantification and comparison of marijuana smoking practices: blunts, joints, and pipesJohn J Mariani
New York State Psychiatric Institute, Division on Substance Abuse, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Drug Alcohol Depend 113:249-51. 2011..Individual variability in use practices limits the utility of this method to estimating within-subject comparisons, rather than between subject comparisons... - Comparison of clinical trial recruitment populations: treatment-seeking characteristics of opioid-, cocaine-, and cannabis-using participantsJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, New York, NY 10032, USA
J Subst Abuse Treat 40:426-30. 2011..These results have implications for clinical trial recruitment and public health efforts directed at encouraging cannabis-dependent individuals to seek treatment... - Effects of research setting on observed depressive symptoms in marijuana usersJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
J Subst Abuse Treat 37:431-4. 2009..e., treatment-seekers are more likely to be experiencing some degree of clinical distress), it is notable that treatment-seeking, and not marijuana use per se, is associated with significantly higher rates of depression... - Levetiracetam for the treatment of co-occurring alcohol dependence and anxiety: case series and reviewJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, New York, New York 10032, USA
Am J Drug Alcohol Abuse 34:683-91. 2008..There is pre-clinical and clinical evidence that levetiracetam, a newer generation anticonvulsant medication, may be efficacious in the treatment of co-occurring alcohol use and anxiety disorders... - Antisocial behavioral syndromes in cocaine and cannabis dependenceJohn J Mariani
New York State Psychiatric Institute, Division on Substance Abuse, New York, NY 10032, USA
Am J Drug Alcohol Abuse 34:405-14. 2008..Antisocial behavioral syndromes are commonly diagnosed in patients with SUD and future research should evaluate prognostic implications of AABS compared to ASPD in a variety of clinical treatment settings... - Quetiapine treatment of zolpidem dependenceJohn J Mariani
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Am J Addict 16:426. 2007 - Treatment strategies for co-occurring ADHD and substance use disordersJohn J Mariani
New York State Psychiatric Institute, New York, New York, USA
Am J Addict 16:45-54; quiz 55-6. 2007..Recommendations for treatment planning and clinical management for patients with co-occurring ADHD and SUD are discussed... 
A randomized, open-label, controlled trial of gabapentin and phenobarbital in the treatment of alcohol withdrawalJohn J Mariani
Department of Psychiatry, Division on Substance Abuse, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Am J Addict 15:76-84. 2006..Given gabapentin's favorable pharmacokinetic profile, further study of its effectiveness in treating alcohol withdrawal is warranted...- Comparison of substance use milestones in cannabis- and cocaine-dependent patientsJonathan T Horey
Division on Substance Abuse, New York Psychiatric Institute, New York, New York 10022, USA
J Addict Dis 31:60-6. 2012..To compare the progression of substance use milestones between cocaine- and cannabis-dependent patients... - Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trialFrances R Levin
New York State Psychiatric Institute, Division of Substance Abuse, New York, NY 10032, USA
Drug Alcohol Depend 116:142-50. 2011..Future trials might test higher doses, combinations of dronabinol with other medications with complementary mechanisms, or with more potent behavioral interventions... - A placebo controlled trial of memantine as an adjunct to oral naltrexone for opioid dependenceAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
Drug Alcohol Depend 119:e23-9. 2011..Preclinical findings suggest that the inhibition of NMDA glutamatergic neurotransmission may have beneficial effects in the treatment of opioid dependence... 
The utility of attention-deficit/hyperactivity disorder screening instruments in individuals seeking treatment for substance use disordersElias Dakwar
New York State Psychiatric Institute, Columbia University, College of Physicians and Surgeons, 1051 Riverside Dr, Unit 66, New York, NY 10032, USA
J Clin Psychiatry 73:e1372-8. 2012..The aim of this study was to determine the sensitivity, specificity, and positive and negative predictive values of 3 commonly used ADHD screening instruments in cocaine-dependent individuals...- A placebo-controlled trial of memantine for cocaine dependence with high-value voucher incentives during a pre-randomization lead-in periodAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
Drug Alcohol Depend 111:97-104. 2010..Targeting the latter subgroup may advance medication development efforts... - Extended-release mixed amphetamine salts and topiramate for cocaine dependence: a randomized controlled trialJohn J Mariani
Division of Substance Abuse, New York State Psychiatric Institute, New York 10032, USA
Biol Psychiatry 72:950-6. 2012..Amphetamine and topiramate have both shown promise for the treatment of cocaine dependence in preclinical and early-stage clinical studies... - Assessment of riboflavin as a tracer substance: Comparison of a qualitative to a quantitative method of riboflavin measurementAbigail J Herron
St Luke s Roosevelt Hospital Center, 324 W 108th Street, 505, New York, NY 10025, United States Columbia University College of Physicians and Surgeons, Department of Psychiatry, 630 West 168th Street, New York, NY 10032, United States Electronic address
Drug Alcohol Depend 128:77-82. 2013..This study compares qualitative visual inspection of fluorescence to quantitative fluorometric analysis of riboflavin concentration in its ability to detect the presence of riboflavin in urine... - A comparison of psychosocial and cognitive functioning between depressed and non-depressed patients with cannabis dependenceAlex M Secora
Division of Substance Abuse, New York State Psychiatric Institute, New York, NY 10032, USA
J Addict Dis 29:325-37. 2010..Based on the authors' results, they concluded that the additive effects of cannabis dependency and depression may only be limited to psychosocial domains and may not extend to cognitive functioning... - Pharmacotherapy for alcohol-related disorders: what clinicians should knowJohn J Mariani
Department of Psychiatry, Division on Substance Abuse, Columbia University, College of Physicians and Surgeons, USA
Harv Rev Psychiatry 12:351-66. 2004..The routine exclusion of alcohol-dependent patients from pharmacotherapy trials of psychiatric disorders presents a barrier to gathering more data. Recommendations for future research are discussed... - Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinolFrances R Levin
New York State Psychiatric Institute, Division on Substance Abuse, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
Drug Alcohol Depend 106:65-8. 2010..We propose that the lack of THCV detection may be due to the variability of available cannabis strains smoked by marijuana users in community settings... - A case report of maintenance valproic acid treatment failing to protect against alcohol withdrawalJohn J Mariani
Am J Addict 14:397-8. 2005
Research Grants
- Anticonvulsant Pharmacotherapy for Sedative-Hypnotic Use DisordersJohn Mariani; Fiscal Year: 2007..Development of an effective treatment strategy would have a direct positive impact on public health. ..