Jeremy Mao

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Comparison of osteogenic potentials of visceral and subcutaneous adipose-derived cells of rabbits
    Ioana A Peptan
    Department of Bioengineering, University of Illinois, Chicago, IL 60612 7211, USA
    Plast Reconstr Surg 117:1462-70. 2006
  2. ncbi request reprint Stem cells and the future of dental care
    Jeremy J Mao
    Columbia University College of Dental Medicine, USA
    N Y State Dent J 74:20-4. 2008
  3. doi request reprint Competitive stem cell recruitment by multiple cytotactic cues
    Avital Mendelson
    Tissue Engineering and Regenerative Medicine Laboratory TERML, Columbia University Medical Center, 630 W 168 St PH7E, New York, NY 10032, USA
    Lab Chip 13:1156-64. 2013
  4. doi request reprint Stem cells in the face: tooth regeneration and beyond
    Jeremy J Mao
    Center for Craniofacial Regeneration, Columbia University Medical Center, 630 West 168 Street PH7E, New York, NY 10032, USA
    Cell Stem Cell 11:291-301. 2012
  5. doi request reprint Regenerative endodontics: barriers and strategies for clinical translation
    Jeremy J Mao
    Center for Craniofacial Regeneration, Columbia University, 630 West 168 Street, PH7E, New York, NY 10032, USA
    Dent Clin North Am 56:639-49. 2012
  6. pmc Craniofacial tissue engineering by stem cells
    J J Mao
    Columbia University College of Dental Medicine and Biomedical Engineering, 630 W 168 St PH7 CDM, New York, NY 10032, USA
    J Dent Res 85:966-79. 2006
  7. doi request reprint Labeling of mesenchymal stem cells with bioconjugated quantum dots
    Bhranti S Shah
    Tissue Engineering and Regenerative Medicine Laboratory, Department of Biomedical Engineering, College of Dental Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Methods Mol Biol 680:61-75. 2011
  8. doi request reprint Adipose tissue engineering from adult human stem cells: a new concept in biosurgery
    Jeffrey M Ahn
    Department of Otolaryngology Head and Neck Surgery, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York 10032, USA
    Facial Plast Surg 26:413-20. 2010
  9. ncbi request reprint Fibroblastic differentiation of human mesenchymal stem cells using connective tissue growth factor
    Chang H Lee
    Department of Orthodontics, University of Illinois, Chicago, IL 60612, USA
    Conf Proc IEEE Eng Med Biol Soc 1:775-8. 2006
  10. ncbi request reprint Continuing differentiation of human mesenchymal stem cells and induced chondrogenic and osteogenic lineages in electrospun PLGA nanofiber scaffold
    Xuejun Xin
    Department of Biomedical Engineering, Columbia University, College of Dental Medicine, Fu Foundation School of Engineering and Applied Sciences, New York, NY 10032, USA
    Biomaterials 28:316-25. 2007

Collaborators

  • Chang H Lee
  • J A Helms
  • S Shi
  • Sahng G Kim
  • Takahiro Suzuki
  • Stanton Gerson
  • Liu Hong
  • James Dennis
  • Scott Hollister
  • Arnold I Caplan
  • J H Elisseeff
  • Eduardo K Moioli
  • Paul A Clark
  • Adel Alhadlaq
  • Michael S Stosich
  • Avital Mendelson
  • Bhranti S Shah
  • Nicholas W Marion
  • Mo Chen
  • Xuejun Xin
  • Jeffrey M Ahn
  • D Rick Sumner
  • Gregory Yourek
  • Ioana A Peptan
  • Antonio X Xin
  • Mohamed N Rahaman
  • Priya Radhakrishnan
  • Rupal V Patel
  • Kai Hu
  • Yuk Kee Cheung
  • Kimi Kong
  • Samuel K Sia
  • Jiali Tan
  • Ziming Dong
  • Kamila Paluch
  • Eric Frank
  • Chad Allred
  • Elena Jones
  • Wenli Zhao
  • Robert DiRaddo
  • Jeffrey Ascherman
  • Azizeh Mitra Yoursef
  • Christine Rohde
  • June K Wu
  • Helaman P Erickson
  • Michael A Stroscio
  • Shan Lal
  • Barb Bastian
  • Mohammad Hussain
  • Gwendolen Reilly
  • Mohammad A Hussain
  • Celeste Gaydos
  • Jesse Guardado
  • Minghui Tang
  • Naama T Lewis
  • Blanka Sharma
  • Donald P Lennon
  • Christopher G Williams
  • Ross A Kopher
  • Aurora Lopez
  • Sara Tomkoria
  • Jing Fang
  • Rong Qiguo

Detail Information

Publications39

  1. ncbi request reprint Comparison of osteogenic potentials of visceral and subcutaneous adipose-derived cells of rabbits
    Ioana A Peptan
    Department of Bioengineering, University of Illinois, Chicago, IL 60612 7211, USA
    Plast Reconstr Surg 117:1462-70. 2006
    ..In the present study, the authors compared the osteogenic potentials of adipose-derived stromal cells from different anatomical sites of rabbits...
  2. ncbi request reprint Stem cells and the future of dental care
    Jeremy J Mao
    Columbia University College of Dental Medicine, USA
    N Y State Dent J 74:20-4. 2008
    ..Metallic alloys, composites and even titanium implants are not permanent solutions. In contrast, stem cell technology will generate native tissue analogs that are compatible with the patient's own...
  3. doi request reprint Competitive stem cell recruitment by multiple cytotactic cues
    Avital Mendelson
    Tissue Engineering and Regenerative Medicine Laboratory TERML, Columbia University Medical Center, 630 W 168 St PH7E, New York, NY 10032, USA
    Lab Chip 13:1156-64. 2013
    ..This new device has the rare capacity to screen molecules that induce cell migration in cancer therapy, drug development and tissue regeneration...
  4. doi request reprint Stem cells in the face: tooth regeneration and beyond
    Jeremy J Mao
    Center for Craniofacial Regeneration, Columbia University Medical Center, 630 West 168 Street PH7E, New York, NY 10032, USA
    Cell Stem Cell 11:291-301. 2012
    ..This perspective article critically analyzes the current status of our understanding of orofacial stem/progenitor cells, identifies gaps in our knowledge, and highlights pathways for the development of regenerative therapies...
  5. doi request reprint Regenerative endodontics: barriers and strategies for clinical translation
    Jeremy J Mao
    Center for Craniofacial Regeneration, Columbia University, 630 West 168 Street, PH7E, New York, NY 10032, USA
    Dent Clin North Am 56:639-49. 2012
    ..Recent work using novel biomaterial scaffolds and growth factors that orchestrate the homing of host endogenous cells represents a departure from traditional cell transplantation approaches and may accelerate clinical translation...
  6. pmc Craniofacial tissue engineering by stem cells
    J J Mao
    Columbia University College of Dental Medicine and Biomedical Engineering, 630 W 168 St PH7 CDM, New York, NY 10032, USA
    J Dent Res 85:966-79. 2006
    ..Craniofacial tissue engineering is likely to be realized in the foreseeable future, and represents an opportunity that dentistry cannot afford to miss...
  7. doi request reprint Labeling of mesenchymal stem cells with bioconjugated quantum dots
    Bhranti S Shah
    Tissue Engineering and Regenerative Medicine Laboratory, Department of Biomedical Engineering, College of Dental Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Methods Mol Biol 680:61-75. 2011
    ..Thus, quantum dots represent an effective cell labeling probe and an alternative to organic dyes and fluorescent proteins for cell labeling and cell tracking...
  8. doi request reprint Adipose tissue engineering from adult human stem cells: a new concept in biosurgery
    Jeffrey M Ahn
    Department of Otolaryngology Head and Neck Surgery, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York 10032, USA
    Facial Plast Surg 26:413-20. 2010
    ..However, the era of biosurgery replacing conventional treatments such as biologically inactive filler injections and alloplastic implants appears to be in the near future...
  9. ncbi request reprint Fibroblastic differentiation of human mesenchymal stem cells using connective tissue growth factor
    Chang H Lee
    Department of Orthodontics, University of Illinois, Chicago, IL 60612, USA
    Conf Proc IEEE Eng Med Biol Soc 1:775-8. 2006
    ..These findings have implications for engineering fibrous tissue by providing the initial evidence of a reproducible protocol for fibroblastic differentiation of hMSCs...
  10. ncbi request reprint Continuing differentiation of human mesenchymal stem cells and induced chondrogenic and osteogenic lineages in electrospun PLGA nanofiber scaffold
    Xuejun Xin
    Department of Biomedical Engineering, Columbia University, College of Dental Medicine, Fu Foundation School of Engineering and Applied Sciences, New York, NY 10032, USA
    Biomaterials 28:316-25. 2007
    ..Consistent with previous work, these findings also suggest that nanofibers may serve as accommodative milieu for not only hMSCs, but also as a 3D carrier vehicle for lineage specific cells...
  11. pmc CTGF directs fibroblast differentiation from human mesenchymal stem/stromal cells and defines connective tissue healing in a rodent injury model
    Chang H Lee
    Tissue Engineering and Regenerative Medicine Laboratory, College of Dental Medicine, Columbia University, New York, New York, USA
    J Clin Invest 120:3340-9. 2010
    ..The knowledge that fibroblasts have a mesenchymal origin may enrich our understanding of organ fibrosis, cancer stroma, ectopic mineralization, scarring, and regeneration...
  12. ncbi request reprint Mesenchymal stem cells and tissue engineering
    Nicholas W Marion
    College of Dental Medicine Fu Foundation School of Engineering and Applied Sciences, Columbia University, New York, New York, USA
    Methods Enzymol 420:339-61. 2006
    ....
  13. ncbi request reprint Adipose tissue engineering from human adult stem cells: clinical implications in plastic and reconstructive surgery
    Michael S Stosich
    College of Dental Medicine and Department of Biomedical Engineering, Columbia University, New York, NY 10032, USA
    Plast Reconstr Surg 119:71-83; discussion 84-5. 2007
    ..This study investigated the shape and dimension maintenance of engineered adipose tissue from adult human mesenchymal stem cells...
  14. pmc Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues
    Eduardo K Moioli
    Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory, College of Dental Medicine, New York, New York, United States of America
    PLoS ONE 3:e3922. 2008
    ....
  15. ncbi request reprint Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering
    Eduardo K Moioli
    Columbia University, Tissue Engineering and Regenerative Medicine Laboratory TERML, College of Dental Medicine, Fu Foundation School of Engineering and Applied Sciences, Department of Biomedical Engineering, New York, NY 10032, USA
    Adv Drug Deliv Rev 59:308-24. 2007
    ....
  16. ncbi request reprint Autologous stem cell regeneration in craniosynostosis
    Eduardo K Moioli
    Tissue Engineering and Regenerative Medicine Laboratory, Columbia University, College of Dental Medicine, New York, NY 10032, USA
    Bone 42:332-40. 2008
    ..The engineered soft tissue-bone interface may have implications in the repair of tendons, ligaments, periosteum and periodontal ligament...
  17. doi request reprint Bioengineering strategies to generate vascularized soft tissue grafts with sustained shape
    Michael S Stosich
    Tissue Engineering and Regenerative Medicine Laboratory, Department of Biomedical Engineering, Columbia University Medical Center, College of Dental Medicine, New York, NY 10032, USA
    Methods 47:116-21. 2009
    ..Ongoing studies have begun to demonstrate the feasibility towards an ultimate goal to generate vascularized soft tissue grafts that maintain anatomically desirable shape and dimensions...
  18. ncbi request reprint Inhibition of osteogenic differentiation of human mesenchymal stem cells
    Eduardo K Moioli
    Department of Biomedical Engineering, College of Dental Medicine, Columbia University, Fu Foundation School of Engineering and Applied Sciences, New York, New York 10032, USA
    Wound Repair Regen 15:413-21. 2007
    ....
  19. pmc Chondrogenesis by chemotactic homing of synovium, bone marrow, and adipose stem cells in vitro
    Avital Mendelson
    Tissue Engineering and Regenerative Medicine Laboratory, Columbia University Medical Center, New York, New York 10032, USA
    FASEB J 25:3496-504. 2011
    ..Thus, homing of multiple stem/progenitor cell populations may potentially serve as an alternative or adjunctive approach to cell transplantation for cartilage regeneration...
  20. doi request reprint Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study
    Chang H Lee
    Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory, New York, NY 10032, USA
    Lancet 376:440-8. 2010
    ..We tested the hypothesis that the articular surface of the synovial joint can regenerate with a biological cue spatially embedded in an anatomically correct bioscaffold...
  21. pmc Tissue formation and vascularization in anatomically shaped human joint condyle ectopically in vivo
    Chang H Lee
    Tissue Engineering and Regenerative Medicine Laboratory, Columbia University Medical Center, New York, New York 10032, USA
    Tissue Eng Part A 15:3923-30. 2009
    ..Scale up is probable by incorporating a combination of stem cells and their progenies in repeating modules of internal microchannels...
  22. ncbi request reprint Labeling of mesenchymal stem cells by bioconjugated quantum dots
    Bhranti S Shah
    College of Dental Medicine, Department of Biomedical Engineering, Fu Foundation School of Engineering and Applied Sciences, Columbia University, New York, New York 10032, USA
    Nano Lett 7:3071-9. 2007
    ..QD-labeled hMSCs remained viable as unlabeled hMSCs from the same subpopulation. These findings suggest the use of bioconjugated QDs as an effective probe for long-term labeling of stem cells...
  23. ncbi request reprint In vitro degradation behavior of photopolymerized PEG hydrogels as tissue engineering scaffold
    Antonio X Xin
    Dept of Dental Med and Biomed Eng, Columbia Univ, New York, NY 10032, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2091-3. 2006
    ..The results indicate that the PEGDA formed hydrogels can be tailored with prompted properties specifically for various cell-based tissue engineering needs...
  24. ncbi request reprint Tissue-engineered osteochondral constructs in the shape of an articular condyle
    Adel Alhadlaq
    Department of Anatomy, Tissue Engineering Laboratory, MC 841, University of Illinois at Chicago, 801 South Paulina Street, Chicago, Illinois 60612, USA
    J Bone Joint Surg Am 87:936-44. 2005
    ..This study describes our continuing effort to optimize the chondrogenic and osteogenic differentiation from mesenchymal stem cells toward engineering articular condyles in vivo...
  25. ncbi request reprint Mesenchymal stem cells: isolation and therapeutics
    Adel Alhadlaq
    Tissue Engineering Laboratory, Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL 60612, USA
    Stem Cells Dev 13:436-48. 2004
    ..The present review not only outlines several approaches relevant to the isolation and therapeutic use of MSCs, but also presents several examples of phenotypic and functional characterization of isolated MSCs and their progeny...
  26. ncbi request reprint Stem-cell-driven regeneration of synovial joints
    Jeremy J Mao
    Tissue Engineering Laboratory, Department of Anatomy and Cell Biology, University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL 60612, USA
    Biol Cell 97:289-301. 2005
    ..Current approaches to regenerate the synovial joint condyle from stem-cell-derived multiple cell lineages may also offer clues for engineering complex organs such as the kidney or liver...
  27. ncbi request reprint Engineered adipose tissue from human mesenchymal stem cells maintains predefined shape and dimension: implications in soft tissue augmentation and reconstruction
    Adel Alhadlaq
    Tissue Engineering Laboratory, Department of Anatomy and Cell Biology, University of Illinois at Chicago, 60612, USA
    Tissue Eng 11:556-66. 2005
    ..These data demonstrate that adipose tissue engineered from human mesenchymal stem cells can retain predefined shape and dimensions for soft tissue augmentation and reconstruction...
  28. ncbi request reprint Ex vivo adipose tissue engineering by human marrow stromal cell seeded gelatin sponge
    Liu Hong
    Department of Orthodontics, University of Illinois at Chicago, Chicago, IL 60612 7211, USA
    Ann Biomed Eng 33:511-7. 2005
    ..The present study indicates that bone MSCs could be a cell resource in tissue engineering adipose tissue, while gelatin sponge could be a good scaffold in this approach to improve the outcome of clinical treatment...
  29. ncbi request reprint Chondrogenesis of mesenchymal stem cells by controlled delivery of transforming growth factor-beta3
    Eduardo K Moioli
    Conf Proc IEEE Eng Med Biol Soc 1:2647-50. 2006
    ..The present study investigates a tissue engineered construct that includes sustained delivery of TGFbeta3 and induces differentiation of hMSC into chondrocytes in situ using injectable thermosensitive gels...
  30. ncbi request reprint Stem cell-based composite tissue constructs for regenerative medicine
    Mohamed N Rahaman
    Department of Bioengineering, University of Illinois at Chicago, 851 S Morgan St, Chicago, Illinois 60607, USA
    Biotechnol Bioeng 91:261-84. 2005
    ....
  31. ncbi request reprint Sustained release of TGFbeta3 from PLGA microspheres and its effect on early osteogenic differentiation of human mesenchymal stem cells
    Eduardo K Moioli
    Tissue Engineering Laboratory, University of Illinois at Chicago, Illinois, USA
    Tissue Eng 12:537-46. 2006
    ..35 ng/mL TGFbeta3 to cell culture (p > 0.05). These findings provide baseline data for potential uses of microencapsulated TGFbeta3 in wound healing and tissue-engineering applications...
  32. ncbi request reprint Adult stem cell driven genesis of human-shaped articular condyle
    Adel Alhadlaq
    Tissue Engineering Laboratory, Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL 60612, USA
    Ann Biomed Eng 32:911-23. 2004
    ..These findings may serve as a primitive proof of concept for ultimate tissue-engineered replacement of degenerated articular condyles via a single population of adult mesenchymal stem cells...
  33. ncbi request reprint Zone-specific micromechanical properties of the extracellular matrices of growth plate cartilage
    Priya Radhakrishnan
    Department of Orthodontics, University of Illinois at Chicago, Chicago, IL 60612 7211, USA
    Ann Biomed Eng 32:284-91. 2004
    ..77 +/- 0.12 MPa, significantly different from the same zone upon transverse indentation. Thus, the extracellular matrix of growth plate cartilage seems to be inhomogenous in its capacity to withstand mechanical stresses...
  34. ncbi request reprint Effects of condylar fibrocartilage on the biomechanical loading of the human temporomandibular joint in a three-dimensional, nonlinear finite element model
    Kai Hu
    Tissue Engineering Laboratory, Department of Orthodontics, University of Illinois at Chicago, 60612, USA
    Med Eng Phys 25:107-13. 2003
    ..These findings lead to a hypothesis that the mandibular condyle more likely functions as a shock absorber than the disc...
  35. ncbi request reprint Growth and development: hereditary and mechanical modulations
    Jeremy J Mao
    Department of Orthodontics, University of Illinois at Chicago, MC 841, 801 S Paulina Street, Chicago, IL 60621, USA
    Am J Orthod Dentofacial Orthop 125:676-89. 2004
    ....
  36. ncbi request reprint Cytoskeletal changes of mesenchymal stem cells during differentiation
    Gregory Yourek
    Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois, USA
    ASAIO J 53:219-28. 2007
    ..These data suggest human mesenchymal stem cells alter their cytoskeletal components during differentiation. Additional studies will address the mechanisms of cytoskeletal changes using biochemical and biophysical methods...
  37. doi request reprint Porous implants as drug delivery vehicles to augment host tissue integration
    Paul A Clark
    Department of Neurological Surgery, University of Wisconsin Madison, Madison, Wisconsin, USA
    FASEB J 22:1684-93. 2008
    ..These findings suggest that solid prostheses can be transformed into porous implants to serve as drug delivery carriers, from which control-released bioactive cues augment host tissue integration...
  38. ncbi request reprint Vascularized adipose tissue grafts from human mesenchymal stem cells with bioactive cues and microchannel conduits
    Michael S Stosich
    Tissue Engineering and Regenerative Medicine Laboratory, College of Dental Medicine, Columbia University, New York, New York 10032, USA
    Tissue Eng 13:2881-90. 2007
    ..Especially, engineered microchannels may provide a generic approach for modifying existing biomaterials by providing conduits for vascularization and/or diffusion...
  39. ncbi request reprint Microstructural and elastic properties of the extracellular matrices of the superficial zone of neonatal articular cartilage by atomic force microscopy
    Rupal V Patel
    Department of Orthodontics, University of Illinois at Chicago, 801 S Paulina Street, Chicago, IL 60612, USA
    Front Biosci 8:a18-25. 2003
    ....

Research Grants27

  1. Stem Cell-Driven Regeneration of the Mandibular Joint
    Jeremy Mao; Fiscal Year: 2006
    ..The anticipated findings may have implications in the ultimate fabrication of functional, tissue-engineered human mandibular condyles using autologous human stem cells for clinical implantation. ..
  2. Stem Cell Based Soft Tissue Reconstruction
    Jeremy Mao; Fiscal Year: 2007
    ..An interdisciplinary team of biomedical engineers, biologists, biomaterial scientists, imaging scientists and surgical consultants have been assembled to meet the challenges of realizing our goals. ..
  3. Engineering of Vascularized Bone
    Jeremy J Mao; Fiscal Year: 2010
    ....
  4. Stem-Cell Based Tissue Engineering in Regenerative Medicine Conference
    Jeremy Mao; Fiscal Year: 2006
    ..abstract_text> ..
  5. ENGINEERING CRANIOFACIAL OSTEOGENESIS--MECHANICAL FORCES
    Jeremy Mao; Fiscal Year: 2004
    ....
  6. Stem Cell Based Soft Tissue Reconstruction
    Jeremy Mao; Fiscal Year: 2009
    ..An interdisciplinary team of biomedical engineers, biologists, biomaterial scientists, imaging scientists and surgical consultants have been assembled to meet the challenges of realizing our goals. ..
  7. Engineering of Vascularized Bone
    Jeremy Mao; Fiscal Year: 2009
    ....
  8. Stem Cell Based Soft Tissue Reconstruction
    Jeremy J Mao; Fiscal Year: 2010
    ..An interdisciplinary team of biomedical engineers, biologists, biomaterial scientists, imaging scientists and surgical consultants have been assembled to meet the challenges of realizing our goals. ..
  9. Tracking stem cells in engineered tissue and organs in vivo and in real time
    Jeremy J Mao; Fiscal Year: 2010
    ..It also has a potential to contribute to our understanding of the engineered osteochondral interface that is of critical value in bioengineered replacement of arthritic joints. ..
  10. Functional Tissue Engineering of Articular Condyle
    Jeremy Mao; Fiscal Year: 2006
    ..The anticipated findings may have implications in the ultimate ex vivo fabrication of tissue-engineered articular condyles using cell-based regenerative approaches. ..