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Species | Dolores MalaspinaSummaryAffiliation: Columbia University Country: USA Publications
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Publications
SPECT imaging of odor identification in schizophreniaD Malaspina
Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Psychiatry Res 82:53-61. 1998..These regions may be unique to schizophrenia or have broader implications for olfactory memory retrieval...
Paternal age and sporadic schizophrenia: evidence for de novo mutationsDolores Malaspina
Columbia University Department of Psychiatry New York State Psychiatric Institute, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Am J Med Genet 114:299-303. 2002..7 years) than familial patients; so later childbirth was not attributable to parental psychiatric illness. These findings support the hypothesis that de novo mutations contribute to the risk for sporadic schizophrenia...- Advancing paternal age and the risk of schizophreniaD Malaspina
New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
Arch Gen Psychiatry 58:361-7. 2001..A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines... - Traumatic brain injury and schizophrenia in members of schizophrenia and bipolar disorder pedigreesD Malaspina
New York State Psychiatric Institute, Columbia University, New York 10032, USA
Am J Psychiatry 158:440-6. 2001.... - Olfaction and social drive in schizophreniaDolores Malaspina
New York State Psychiatric Institute, Columbia University, New York, USA
Arch Gen Psychiatry 60:578-84. 2003..We examined whether SIDs in schizophrenia were related broadly to negative symptoms, as are a number of other neuropsychological measures, or whether they might show a more specific relationship with social drive... - Paternal factors and schizophrenia risk: de novo mutations and imprintingD Malaspina
Columbia University Department of Psychiatry, New York State Psychiatric Institute, NY 10032, USA
Schizophr Bull 27:379-93. 2001..Finally, it is proposed that environmental exposures of the father, as well as those of the mother and developing fetus, may be relevant to the etiology of schizophrenia... - Relation of familial schizophrenia to negative symptoms but not to the deficit syndromeD Malaspina
Schizophrenia Research Unit, Department of Clinical Psychobiology, New York State Psychiatric Institute, NY 10032, USA
Am J Psychiatry 157:994-1003. 2000..Although a family history of schizophrenia has been associated with negative symptoms, family history is inconsistently related to the presence of the deficit syndrome... - The reliability and clinical correlates of figure-ground perception in schizophreniaDolores Malaspina
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
J Neuropsychiatry Clin Neurosci 16:277-83. 2004.... - Schizophrenia subgroups differing in dichotic listening laterality also differ in neurometabolism and symptomatologyD Malaspina
Department of Psychiatry, Columbia University, New York, USA
J Neuropsychiatry Clin Neurosci 12:485-92. 2000..In contrast, the prefrontal-medial temporal imbalance present in both patient groups may typify the schizophrenia syndrome... - Resting neural activity distinguishes subgroups of schizophrenia patientsDolores Malaspina
New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Biol Psychiatry 56:931-7. 2004..We previously demonstrated symptom and physiologic differences between familial and sporadic schizophrenia patients and hypothesized that the groups would show different resting regional cerebral blood flow (rCBF) patterns... - Paternal age and intelligence: implications for age-related genomic changes in male germ cellsDolores Malaspina
New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
Psychiatr Genet 15:117-25. 2005..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence... - Incidence of schizophrenia among second-generation immigrants in the jerusalem perinatal cohortCheryl Corcoran
New York State Psychiatric Institute, Unit 2, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Bull 35:596-602. 2009..Few contemporary studies have evaluated the risk of schizophrenia among second-generation immigrants in other parts of the world... - Olfactory processing, sex effects and heterogeneity in schizophreniaDolores Malaspina
New York University School of Medicine, Institute for Social and Psychiatric Initiatives, 500 1st Avenue, NBV 22N10, New York, NY 10016, USA
Schizophr Res 135:144-51. 2012.... - Sleep duration associated with mortality in elderly, but not middle-aged, adults in a large US sampleJames E Gangwisch
Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, New York, NY 10032, USA
Sleep 31:1087-96. 2008..No epidemiologic studies have published multivariate analyses stratified by age, even though life expectancy is 75 years and the majority of deaths occur in the elderly... - Sleep duration as a risk factor for diabetes incidence in a large U.S. sampleJames E Gangwisch
Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, 1051 Riverside Drive, Mailbox 2, New York, NY 10032, USA
Sleep 30:1667-73. 2007..No plausible mechanism has been identified by which long sleep duration could lead to diabetes... - Temporal association of cannabis use with symptoms in individuals at clinical high risk for psychosisCheryl M Corcoran
Columbia University, Department of Psychiatry, New York, NY, United States
Schizophr Res 106:286-93. 2008..Cannabis use is reported to increase the risk for psychosis, but no prospective study has longitudinally examined drug use and symptoms concurrently in clinical high risk cases... 
Olfaction and cognition in schizophrenia: sex mattersDolores Malaspina
Institute for Social and Psychiatric Initiatives, New York University School of Medicine, 500 1st Ave, NBV 22N14, New York, NY 10016, USA
J Neuropsychiatry Clin Neurosci 24:165-75. 2012..These findings indicate significant sex differences in olfactory processing in schizophrenia. Combining the sexes in research analyses may obscure important differences...- Earlier parental set bedtimes as a protective factor against depression and suicidal ideationJames E Gangwisch
Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10032, USA
Sleep 33:97-106. 2010..Depression in an adolescent can affect his/her chosen bedtime, but it is less likely to affect a parent's chosen set bedtime which can establish a relatively stable upper limit that can directly affect sleep duration... - Later paternal age and sex differences in schizophrenia symptomsPaul J Rosenfield
Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10019, USA
Schizophr Res 116:191-5. 2010..This study examined if PARS exhibits the symptom profile and sex differences that are consistently observed for schizophrenia in general, wherein males have an earlier onset age and more severe negative symptoms than females... - Effect of socioeconomic status and parents' education at birth on risk of schizophrenia in offspringCheryl Corcoran
Dept of Psychiatry, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 2, New York, NY 10032, USA
Soc Psychiatry Psychiatr Epidemiol 44:265-71. 2009..Instead, a modest increase in risk for schizophrenia was observed only for those born at the bottom of the social ladder... - Catatonic schizophrenia: a cohort prospective studyKarine Kleinhaus
Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Schizophr Bull 38:331-7. 2012..This study is the first to describe catatonia using prospectively collected data and to examine how catatonic schizophrenia differs from, or resembles, other types of schizophrenia... - Olfactory acuity is associated with mood and function in a pilot study of stable bipolar disorder patientsCaitlin Hardy
Department of Psychiatry, New York University NYU School of Medicine, New York, NY, USA
Bipolar Disord 14:109-17. 2012..Olfactory dysfunction is described in several neuropsychiatric disorders but there is little research on olfactory processing in bipolar disorder... - Maternal household crowding during pregnancy and the offspring's risk of schizophreniaDavid Kimhy
Department of Psychiatry, Columbia University, New York, NY 10032, USA
Schizophr Res 86:23-9. 2006..We tested the hypothesis that a similar link is present in humans... - Theory of Mind in patients at clinical high risk for psychosisArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Res 131:11-7. 2011..As capacity for ToM normally advances with brain maturation, research on ToM in individuals at heightened clinical risk for psychosis may reveal developmental differences independent of disease based differences... - The factorial structure of the schedule for the deficit syndrome in schizophreniaDavid Kimhy
Department of Psychiatry, Box 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Bull 32:274-8. 2006..The mean severity of symptoms was 2.25 (S.D. = 1.06). We discuss possible links between the obtained factors and putative neurobiological mechanisms, as well as directions for future research... - Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent HealthJames E Gangwisch
Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Cognitive Neuroscience, 1051 Riverside Drive, Unit 74, New York, NY 10032, USA
Sleep 33:956-61. 2010..No previous published population studies have examined the longitudinal relationship between sleep duration and high cholesterol... - Etiological heterogeneity and intelligence test scores in patients with schizophreniaRachel Wolitzky
Department of Medical Genetics, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
J Clin Exp Neuropsychol 28:167-77. 2006..Overall, the results suggest that sporadic patients have better perceptual-organizational skills and faster speed of processing... - Validity of a 'proxy' for the deficit syndrome derived from the Positive And Negative Syndrome Scale (PANSS)Raymond R Goetz
Columbia University, Department of Psychiatry, New York State Psychiatric Institute, Research Foundation for Mental Hygiene, Schizophrenia Research Unit, New York 10032, United States
Schizophr Res 93:169-77. 2007..Further study is indicated before the PDS as extracted from the PANSS can be used in lieu of the SDS for identifying patients with this syndrome... - Olfactory identification and WAIS-R performance in deficit and nondeficit schizophreniaRegine Anna Seckinger
New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
Schizophr Res 69:55-65. 2004..If so, then the relationship of University of Pennsylvania Smell Identification Test (UPSIT) scores with other neurocognitive measures in DS patients may point to the neural substrate of the deficit syndrome... - Insomnia and sleep duration as mediators of the relationship between depression and hypertension incidenceJames E Gangwisch
Division of Cognitive Neuroscience, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Am J Hypertens 23:62-9. 2010..No previous published population studies have examined whether insomnia and sleep duration mediate the relationship between depression and hypertension incidence... - Trajectory to a first episode of psychosis: a qualitative research study with familiesCheryl Corcoran
Department of Psychiatry New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
Early Interv Psychiatry 1:308-15. 2007..Qualitative research methods can be used to begin to elucidate the temporal unfolding of symptoms leading to a first episode of psychosis, and its impact on families... - Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findingsMary C Perrin
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, 10032, USA
Schizophr Res 90:251-4. 2007..We observed an increased incidence of schizophrenia in offspring of parents who were dry cleaners (RR=3.4, 95% CI, 1.3-9.2, p=0.01). Tetrachloroethylene exposure warrants further investigation as a risk factor for schizophrenia... - Advancing paternal age and autismAbraham Reichenberg
Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
Arch Gen Psychiatry 63:1026-32. 2006..Maternal and paternal ages are associated with neurodevelopmental disorders... - Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disordersScott A Schobel
Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York, USA
Arch Gen Psychiatry 66:938-46. 2009..Because schizophrenia and related disorders have a chronic time course and subtle histopathology, it is difficult to identify which brain regions are differentially targeted... - Stigma in families of individuals in early stages of psychotic illness: family stigma and early psychosisCeline Wong
Department of Psychiatry, Columbia University, New York, New York, USA
Early Interv Psychiatry 3:108-15. 2009..These forms of stigma may present a barrier to help seeking. However, little is known about stigma in the early stages of evolving psychotic disorder... - Neuronal generator patterns of olfactory event-related brain potentials in schizophreniaJürgen Kayser
Division of Cognitive Neuroscience, New York State Psychiatric Institute, New York, New York 10032, USA
Psychophysiology 47:1075-86. 2010..N1 sink and P2 source were markedly reduced in patients for high intensity stimuli, providing further neurophysiological evidence of olfactory dysfunction in schizophrenia... - Does unwantedness of pregnancy predict schizophrenia in the offspring? Findings from a prospective birth cohort studyDaniel B Herman
New York State Psychiatric Institute, New York, NY, USA
Soc Psychiatry Psychiatr Epidemiol 41:605-10. 2006..We sought to replicate (or refute) a previous report of an association between unwantedness of a pregnancy and the risk of schizophrenia in the offspring... - Paternal age and risk of schizophrenia in adult offspringAlan S Brown
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
Am J Psychiatry 159:1528-33. 2002..The study examined the relation between paternal age at the time of birth and risk of schizophrenia in the adult offspring... - Anterior hippocampal and orbitofrontal cortical structural brain abnormalities in association with cognitive deficits in schizophreniaScott A Schobel
Center for Prevention and Evaluation, New York State Psychiatric Institute, USA
Schizophr Res 114:110-8. 2009..As an exploratory study goal, we investigated the relation of neurocognition to brain structure in schizophrenia patients... - Childhood trauma and prodromal symptoms among individuals at clinical high risk for psychosisJudy L Thompson
Columbia University, Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Res 108:176-81. 2009..However, little is known about the prevalence of childhood trauma and its relationship to attenuated positive and other symptoms in individuals at heightened clinical risk for psychosis... - Older paternal age strongly increases the morbidity for schizophrenia in sisters of affected femalesMary Perrin
Department of Psychiatry, New York University School of Medicine, New York, New York, USA
Am J Med Genet B Neuropsychiatr Genet 153:1329-35. 2010..The authors speculate that the hypothesized paternally expressed genes on the X chromosome might play some role in these observations... - Olfactory deficits, cognition and negative symptoms in early onset psychosisCheryl Corcoran
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Res 80:283-93. 2005..However, smell identification has not been examined in adolescents with early onset psychosis, wherein diagnosis is often obscure, and there are few prognostic predictors... - Schizophrenia comorbid with panic disorder: evidence for distinct cognitive profilesErica Kirsten Rapp
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
Psychiatry Res 197:206-11. 2012..These data offer further support for a definable panic-psychosis subtype and suggest new etiological pathways for future research... - Concurrent measurement of "real-world" stress and arousal in individuals with psychosis: assessing the feasibility and validity of a novel methodologyDavid Kimhy
Department of Psychiatry, Box 55, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Schizophr Bull 36:1131-9. 2010..Our aim is to the test the feasibility and validity of a novel methodology designed to measure concurrent stress and arousal in individuals with psychosis during "real-world" daily functioning... - Computerized experience sampling method (ESMc): assessing feasibility and validity among individuals with schizophreniaDavid Kimhy
Department of Psychiatry, Unit 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
J Psychiatr Res 40:221-30. 2006..The authors discuss the potential applications of combining ESMc with ambulatory physiological measures... - A brief smell identification test discriminates between deficit and non-deficit schizophreniaNora Goudsmit
New York State Psychiatric Institute and Columbia University Departments of Psychiatry and the College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA
Psychiatry Res 120:155-64. 2003..The results of this study support the utility of the B-SIT for schizophrenia research and highlight the robustness of the relationship between SID and social dysfunction in schizophrenia... - Odor identification, eye tracking and deficit syndrome schizophreniaDolores Malaspina
New York State Psychiatric Institute, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
Biol Psychiatry 51:809-15. 2002..These data further support the notion that the DS defines a homogeneous subgroup of schizophrenia patients and further suggest that dysfunction in the neural circuitry of olfaction may contribute to its pathophysiology... - Trail making and olfaction in schizophrenia: implications for processing speedNora Goudsmit
Department of Medical Genetics, New York State Psychiatric Institute, New York, NY 10032, USA
CNS Spectr 9:344-9, 356. 2004..10, P=.008 and R2=.05, P=.04). CONCLUSION: Linking neurocognition to smell identification deficits may prove to be an essential marker for schizophrenia research... - The Jerusalem Perinatal Study cohort, 1964-2005: methods and a review of the main resultsSusan Harlap
Department of Epidemiology, Mailman School of Public Health, New York 10032, USA
Paediatr Perinat Epidemiol 21:256-73. 2007..Characteristics of this unique population are shown. Findings from the study are reviewed and a list of references is provided. The cohorts provide a unique source of data for a wide variety of studies... - Comparable family burden in families of clinical high-risk and recent-onset psychosis patientsCeline Wong
Department of Psychiatry, Columbia University, New York, USA
Early Interv Psychiatry 2:256-61. 2008..In this exploratory study, we examined the extent of burden reported by families of patients during a putative prodromal period and in the after-math of psychosis onset... - Racial and ethnic effects on psychotic psychiatric diagnostic changes from admission to discharge: a retrospective chart reviewDeidre M Anglin
Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York 10032, USA
J Clin Psychiatry 69:464-9. 2008..We examined the frequency upon admission and at discharge and further explored the pattern of diagnostic changes that occurred by racial/ethnic group... - A model of verbal memory impairments in schizophrenia: two systems and their associations with underlying cognitive processes and clinical symptomsGildas Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
Psychol Med 35:133-42. 2005..The results have been reported in previous papers. In this paper we show how all these data could be integrated into a consistent pattern of associations... - White matter integrity and lack of insight in schizophrenia and schizoaffective disorderDaniel Antonius
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Schizophr Res 128:76-82. 2011..Despite the importance of this issue, the neural correlates of insight deficits in schizophrenia remain poorly understood... - Critical periods and the developmental origins of disease: an epigenetic perspective of schizophreniaMary Perrin
New York University School of Medicine, Social and Psychiatric Initiatives InSPIRES, New York, New York 10016, USA
Ann N Y Acad Sci 1204:E8-13. 2010..This introduction considers the possibility that epigenetic change that may occur as paternal age advances or during fetal adversity may be causally related to the susceptibility for schizophrenia... - Aberrant epigenetic regulation could explain the relationship of paternal age to schizophreniaMary C Perrin
Department of Psychiatry, School of Medicine, New York University, New York, NY, USA
Schizophr Bull 33:1270-3. 2007..This article will discuss parental imprinting on the autosomal and X chromosomes and the alterations in epigenetic regulation that may lead to such errors... - Suicide attempts in schizophrenia: the role of command auditory hallucinations for suicideJill M Harkavy-Friedman
New York State Psychiatric Institute, New York, N Y, USA
J Clin Psychiatry 64:871-4. 2003..We examined the relationship between CAHS and demographic and clinical variables. We also investigated the relationship between CAHS and suicide attempts... - Delusions in individuals with schizophrenia: factor structure, clinical correlates, and putative neurobiologyDavid Kimhy
Department of Psychiatry, Columbia University, New York, NY 10032, USA
Psychopathology 38:338-44. 2005..Our goal is to examine the factor structure of delusions in antipsychotic-free individuals with diagnoses of schizophrenia/schizoaffective disorder... - Paternal age and preeclampsiaSusan Harlap
Department of Obstetrics and Gynecology and Kaplan Cancer Center, New York University School of Medicine, New York, NY 10016, USA
Epidemiology 13:660-7. 2002..Paternal aging is associated with premeiotic damage to spermatogonia, a mechanism by which new point mutations are introduced into the gene pool. We hypothesized that paternal age might contribute to preeclampsia... - Avolition and expressive deficits capture negative symptom phenomenology: implications for DSM-5 and schizophrenia researchJulie W Messinger
Institute for Social and Psychiatric Initiatives InSPIRES, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Clin Psychol Rev 31:161-8. 2011..We recommend that these two domains should be assessed as separate dimensions in the DSM-5 criteria... - Effects of excessive glucocorticoid receptor stimulation during early gestation on psychomotor and social behavior in the ratKarine Kleinhaus
Department of Psychiatry New York University Medical Center, New York, NY, USA
Dev Psychobiol 52:121-32. 2010..Moreover, some of these deficits may be mediated by alterations in postnatal maternal behavior and physiology produced by early gestational exposure to excess glucocorticoids... - Ethnicity effects on clinical diagnoses compared to best-estimate research diagnoses in patients with psychosis: a retrospective medical chart reviewDeidre M Anglin
Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
J Clin Psychiatry 69:941-5. 2008..Ethnicity effects on diagnoses are frequently reported and have variably been attributed to diagnostic biases versus ethnic differences in environmental exposures, and other factors... - rTMS strategies for the study and treatment of schizophrenia: a reviewArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, Cabrini Hospital, Mt Sinai Medical Center, New York, NY 10032, USA
Int J Neuropsychopharmacol 11:563-76. 2008..Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy... - A qualitative research study of the evolution of symptoms in individuals identified as prodromal to psychosisCheryl Corcoran
New York State Psychiatric Institute Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Psychiatr Q 74:313-32. 2003..Although preliminary, these results suggest that a trajectory of change in personality, relationships, and behavior from an essentially normal baseline may be consistent with increased risk for psychosis among prodromal adolescents... - The stress cascade and schizophrenia: etiology and onsetCheryl Corcoran
New York State Psychiatric Institute Columbia University, New York, NY 10032, USA
Schizophr Bull 29:671-92. 2003.... - Self-reported coping strategies in families of patients in early stages of psychotic disorder: an exploratory studyRuth Gerson
Department of Psychiatry, New York University, New York, New York, USA
Early Interv Psychiatry 5:76-80. 2011..g. reinterpretation) and potentially maladaptive 'avoidant' strategies (denial/disengagement, use of alcohol and drugs). Little is known about coping strategies used by families of individuals with incipient or emergent psychosis... - Clinical and cognitive factors associated with verbal memory task performance in patients with schizophreniaG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
Am J Psychiatry 158:758-64. 2001..They wished to determine the specific contribution of each of these factors to various types of memory impairment... - Twin pregnancy and the risk of schizophreniaK Kleinhaus
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, United States
Schizophr Res 105:197-200. 2008..Previous studies report contradictory findings on the risk for schizophrenia in twins... - Schizophrenia and birthplace of paternal and maternal grandfather in the Jerusalem perinatal cohort prospective studyS Harlap
Department of Psychiatry, New York University School of Medicine, NY 10016, USA
Schizophr Res 111:23-31. 2009..Such a locus, if it exists, might involve the X chromosome... - High-frequency prefrontal repetitive transcranial magnetic stimulation for the negative symptoms of schizophrenia: a case seriesArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, New York, NY, USA
J ECT 27:11-7. 2011..This pilot study assessed higher doses of rTMS and assessed particular demographic factors that may influence treatment response... - Multivoxel proton MR spectroscopy used to distinguish anterior cingulate metabolic abnormalities in patients with schizophreniaCaitlin J Hardy
Department of Radiology, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
Radiology 261:542-50. 2011..To test the hypothesis that anterior cingulate cortex (ACC) subregions in patients with schizophrenia are metabolically different from those in healthy control subjects... - Anxiety and substance use comorbidity among inpatients with schizophreniaRenee D Goodwin
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 43, New York 10032, USA
Schizophr Res 61:89-95. 2003..To determine the association between lifetime anxiety symptoms and anxiety disorders and substance use disorders among patients with schizophrenia... - Family history of affective illness in schizophrenia patients: symptoms and cognitionDeidre Anglin
Department of Psychology, The City College and The Graduate Center, City University of New York, United States
Schizophr Res 110:24-7. 2009..Schizophrenia patients with a family history of affective disorder may be a distinct subtype in the group of schizophrenias and may be biologically more similar to patients with serious affective disorder... - The concept of population prevention: application to schizophreniaRamin Mojtabai
Department of Psychiatry, Columbia University, USA
Schizophr Bull 29:791-801. 2003..The article concludes that population and high-risk prevention strategies can be complementary and that it may be feasible and appropriate to use them in combination... - Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination SurveyJames E Gangwisch
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Hypertension 47:833-9. 2006..Short sleep duration could, therefore, be a significant risk factor for hypertension... - Prodromal interventions for schizophrenia vulnerability: the risks of being "at risk"Cheryl Corcoran
New York State Psychiatric Institute and the Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, United States
Schizophr Res 73:173-84. 2005.... - Inadequate sleep as a risk factor for obesity: analyses of the NHANES IJames E Gangwisch
Mailman School of Public Health, Department of Epidemiology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Sleep 28:1289-96. 2005..This study examines cross-sectional and longitudinal data from a large United States sample to determine whether sleep duration is associated with obesity and weight gain... - Revisiting the backward masking deficit in schizophrenia: individual differences in performance and modeling with transcranial magnetic stimulationBruce Luber
Brain Stimulation and Therapeutic Modulation Division, New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 62:793-9. 2007..In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically... - Brain event-related potentials (ERPs) in schizophrenia during a word recognition memory taskJ Kayser
Department of Biopsychology, New York State Psychiatric Institute, New York, NY 10032, USA
Int J Psychophysiol 34:249-65. 1999..These findings suggest that impaired word recognition in schizophrenia may arise from a left lateralized deficit at an early stage of processing, beginning at 200-300 ms after word onset... - NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigreesC A Kaufmann
College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Am J Med Genet 81:282-9. 1998.... - Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studiesL S Kegeles
Department of Psychiatry, Columbia University, New York, NY, USA
Psychiatry Res 98:163-75. 2000..The preliminary finding of a lateralized abnormality in Glx is consistent with postmortem findings of asymmetric neurochemical temporal lobe abnormalities in schizophrenia... - Depression, psychomotor retardation, negative symptoms, and memory in schizophreniaG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
Neuropsychiatry Neuropsychol Behav Neurol 13:177-83. 2000..The purpose of this study was to examine the relations between depression, psychomotor retardation, and negative symptoms in schizophrenia as well as the specific contribution of each of these factors to memory impairment... - Paternal age and spontaneous abortionK Kleinhaus
Epidemiology Department, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Obstet Gynecol 108:369-77. 2006..To evaluate the influence of paternal age upon spontaneous abortion... - Visual form perception: a comparison of individuals at high risk for psychosis, recent onset schizophrenia and chronic schizophreniaD Kimhy
Department of Psychiatry, Columbia University, New York, NY 10032, USA
Schizophr Res 97:25-34. 2007..These deficits are discussed in the context of the putative neurobiological underpinnings of visual deficits and the developmental pathophysiology of psychosis in schizophrenia... - The relationship of social function to depressive and negative symptoms in individuals at clinical high risk for psychosisC M Corcoran
Centre of Prevention and Evaluation, Department of Psychiatry, New York State Psychiatric Institute at Columbia University, New York, NY 10032, USA
Psychol Med 41:251-61. 2011..It is unclear if social symptoms in clinical high-risk patients reflect depressive symptoms or are a manifestation of negative symptoms... - Acute maternal stress in pregnancy and schizophrenia in offspring: a cohort prospective studyD Malaspina
Department of Psychiatry, New York University School of Medicine, New York, NY, USA
BMC Psychiatry 8:71. 2008..We aimed to describe the consequence of an acute maternal stress, through a follow-up of offspring whose mothers were pregnant during the Arab-Israeli war of 1967. A priori, we focused on gestational month and offspring's sex... - Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium ConsortiumS V Faraone
Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, USA
Am J Med Genet 81:290-5. 1998..4, P = .0004) and its neighbor, D10S582 (NPL Z = 3.2, P = .0006)... - Positive symptomatology and source-monitoring failure in schizophrenia--an analysis of symptom-specific effectsG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
Psychiatry Res 95:119-31. 2000..However, this finer-grained analysis revealed that the three of them were in fact associated with hallucinations and/or delusions. On the other hand, thought disorganisation appeared to be independent from these mechanisms... - Psychiatric assessment of aggressive patients: a violent attack on a residentDaniel Antonius
New York University School of Medicine, New York, NY 10016, USA
Am J Psychiatry 167:253-9. 2010..This report illustrates common deficiencies in the prevention of violence on inpatient psychiatric units and in the reporting and response to an assault, and has implications for residency and clinician training... - Opposite links of positive and negative symptomatology with memory errors in schizophreniaG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
Psychiatry Res 88:15-24. 1999..Fewer errors were specifically associated with more affective flattening, alogia and anhedonia, whereas avolition was entirely unrelated to them... - Memory and schizophrenia: differential link of processing speed and selective attention with two levels of encodingG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute and Creedmoor Psychiatric Center, New York, NY, USA
J Psychiatr Res 34:121-7. 2000..Selective attention only contributed to the superficial encoding processes. Thus, slowing of processing speed in schizophrenia seems to be more crucial for memory performance, since it affects memory in a pervasive way... - Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7)R Freedman
Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262, USA
Am J Med Genet 105:20-2. 2001..Replication of this result was found in an additional set of families. The results support this region as a chromosomal location involved in the genetic transmission of schizophrenia... - Preventing clinical deterioration in the course of schizophrenia: the potential for neuroprotectionJeffrey A Lieberman
Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, USA
J Clin Psychiatry 67:983-90. 2006 - Human hippocampal subfields in young adults at 7.0 T: feasibility of imagingVasthie Prudent
Departments of Radiology and Psychiatry, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
Radiology 254:900-6. 2010..This imaging technique might be used to detect cellular disarray and degenerative changes in this sensitive circuit earlier than at 1.5 T or even 3.0 T. (c) RSNA, 2010... - Schizophrenia: a neurodevelopmental or a neurodegenerative disorderDolores Malaspina
Department of Psychiatry and New York State Psychiatric Institute, Columbia University, New York, USA
J Clin Psychiatry 67:e07. 2006.... - A.E. Bennett Research Award. Prenatal rubella, premorbid abnormalities, and adult schizophreniaA S Brown
Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 49:473-86. 2001..CONCLUSIONS: These findings link a known prenatal exposure, a deviant neurodevelopmental trajectory in childhood and adolescence, and SSP in adulthood within the same individuals... - Medications and verbal memory impairment in schizophrenia: the role of anticholinergic drugsG Brébion
Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
Psychol Med 34:369-74. 2004..We wished to assess the effect of three types of medication on verbal memory impairments in schizophrenia... - Growth and schizophrenia: aetiology, epidemiology and epigeneticsD Malaspina
Department of Psychiatry, New York University School ofMedicine, New York, NY 10016, USA
Novartis Found Symp 289:196-203; discussion 203-7, 238-40. 2008..These findings suggest exciting new directions for research into the aetiology of schizophrenia... - Evidence for the multigenic inheritance of schizophreniaR Freedman
Department of Psychiatry, Denver VA Medical Center and University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Am J Med Genet 105:794-800. 2001.... - Loss aversion in schizophreniaFabien Tremeau
Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, United States
Schizophr Res 103:121-8. 2008..Loss aversion is conceived as an affective interference in cognitive processes such as judgment and decision-making. Loss aversion in non-risky choices has not been studied in schizophrenia... - Growth trajectory during early life and risk of adult schizophreniaMegan A Perrin
The Cognitive Neurophysiology Laboratory, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA
Br J Psychiatry 191:512-20. 2007..Growth abnormalities have been suggested as a precursor to schizophrenia, but previous studies have not assessed growth patterns using repeated measures... - Sensitivity of ICD-10 diagnosis of psychotic disorders in the Israeli National Hospitalization Registry compared with RDC diagnoses based on SADS-LMark Weiser
Department of Psychiatry, Sheba Medical Center, Tel Hashomer 52621, Israel
Compr Psychiatry 46:38-42. 2005..This study assessed the sensitivity of the diagnosis of psychotic disorders ( International Statistical Classification of Diseases, 10th Revision [ ICD-10 ] F20.0-F29.9) and schizophrenia ( ICD-10 F20.0-F20.9) in the Registry...