Dolores Malaspina

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint SPECT imaging of odor identification in schizophrenia
    D Malaspina
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Psychiatry Res 82:53-61. 1998
  2. ncbi request reprint Traumatic brain injury and schizophrenia in members of schizophrenia and bipolar disorder pedigrees
    D Malaspina
    New York State Psychiatric Institute, Columbia University, New York 10032, USA
    Am J Psychiatry 158:440-6. 2001
  3. ncbi request reprint Schizophrenia subgroups differing in dichotic listening laterality also differ in neurometabolism and symptomatology
    D Malaspina
    Department of Psychiatry, Columbia University, New York, USA
    J Neuropsychiatry Clin Neurosci 12:485-92. 2000
  4. pmc Resting neural activity distinguishes subgroups of schizophrenia patients
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 56:931-7. 2004
  5. ncbi request reprint Relation of familial schizophrenia to negative symptoms but not to the deficit syndrome
    D Malaspina
    Schizophrenia Research Unit, Department of Clinical Psychobiology, New York State Psychiatric Institute, NY 10032, USA
    Am J Psychiatry 157:994-1003. 2000
  6. ncbi request reprint Advancing paternal age and the risk of schizophrenia
    D Malaspina
    New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
    Arch Gen Psychiatry 58:361-7. 2001
  7. pmc Paternal factors and schizophrenia risk: de novo mutations and imprinting
    D Malaspina
    Columbia University Department of Psychiatry, New York State Psychiatric Institute, NY 10032, USA
    Schizophr Bull 27:379-93. 2001
  8. pmc Paternal age and sporadic schizophrenia: evidence for de novo mutations
    Dolores Malaspina
    Columbia University Department of Psychiatry New York State Psychiatric Institute, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Am J Med Genet 114:299-303. 2002
  9. ncbi request reprint The reliability and clinical correlates of figure-ground perception in schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Neuropsychiatry Clin Neurosci 16:277-83. 2004
  10. ncbi request reprint Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint SPECT imaging of odor identification in schizophrenia
    D Malaspina
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Psychiatry Res 82:53-61. 1998
    ..These regions may be unique to schizophrenia or have broader implications for olfactory memory retrieval...
  2. ncbi request reprint Traumatic brain injury and schizophrenia in members of schizophrenia and bipolar disorder pedigrees
    D Malaspina
    New York State Psychiatric Institute, Columbia University, New York 10032, USA
    Am J Psychiatry 158:440-6. 2001
    ....
  3. ncbi request reprint Schizophrenia subgroups differing in dichotic listening laterality also differ in neurometabolism and symptomatology
    D Malaspina
    Department of Psychiatry, Columbia University, New York, USA
    J Neuropsychiatry Clin Neurosci 12:485-92. 2000
    ..In contrast, the prefrontal-medial temporal imbalance present in both patient groups may typify the schizophrenia syndrome...
  4. pmc Resting neural activity distinguishes subgroups of schizophrenia patients
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 56:931-7. 2004
    ..We previously demonstrated symptom and physiologic differences between familial and sporadic schizophrenia patients and hypothesized that the groups would show different resting regional cerebral blood flow (rCBF) patterns...
  5. ncbi request reprint Relation of familial schizophrenia to negative symptoms but not to the deficit syndrome
    D Malaspina
    Schizophrenia Research Unit, Department of Clinical Psychobiology, New York State Psychiatric Institute, NY 10032, USA
    Am J Psychiatry 157:994-1003. 2000
    ..Although a family history of schizophrenia has been associated with negative symptoms, family history is inconsistently related to the presence of the deficit syndrome...
  6. ncbi request reprint Advancing paternal age and the risk of schizophrenia
    D Malaspina
    New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
    Arch Gen Psychiatry 58:361-7. 2001
    ..A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines...
  7. pmc Paternal factors and schizophrenia risk: de novo mutations and imprinting
    D Malaspina
    Columbia University Department of Psychiatry, New York State Psychiatric Institute, NY 10032, USA
    Schizophr Bull 27:379-93. 2001
    ..Finally, it is proposed that environmental exposures of the father, as well as those of the mother and developing fetus, may be relevant to the etiology of schizophrenia...
  8. pmc Paternal age and sporadic schizophrenia: evidence for de novo mutations
    Dolores Malaspina
    Columbia University Department of Psychiatry New York State Psychiatric Institute, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Am J Med Genet 114:299-303. 2002
    ..7 years) than familial patients; so later childbirth was not attributable to parental psychiatric illness. These findings support the hypothesis that de novo mutations contribute to the risk for sporadic schizophrenia...
  9. ncbi request reprint The reliability and clinical correlates of figure-ground perception in schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Neuropsychiatry Clin Neurosci 16:277-83. 2004
    ....
  10. ncbi request reprint Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005
    ..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence...
  11. ncbi request reprint Olfaction and social drive in schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, New York, USA
    Arch Gen Psychiatry 60:578-84. 2003
    ..We examined whether SIDs in schizophrenia were related broadly to negative symptoms, as are a number of other neuropsychological measures, or whether they might show a more specific relationship with social drive...
  12. pmc Incidence of schizophrenia among second-generation immigrants in the jerusalem perinatal cohort
    Cheryl Corcoran
    New York State Psychiatric Institute, Unit 2, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 35:596-602. 2009
    ..Few contemporary studies have evaluated the risk of schizophrenia among second-generation immigrants in other parts of the world...
  13. pmc Olfactory processing, sex effects and heterogeneity in schizophrenia
    Dolores Malaspina
    New York University School of Medicine, Institute for Social and Psychiatric Initiatives, 500 1st Avenue, NBV 22N10, New York, NY 10016, USA
    Schizophr Res 135:144-51. 2012
    ....
  14. pmc Sleep duration associated with mortality in elderly, but not middle-aged, adults in a large US sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, New York, NY 10032, USA
    Sleep 31:1087-96. 2008
    ..No epidemiologic studies have published multivariate analyses stratified by age, even though life expectancy is 75 years and the majority of deaths occur in the elderly...
  15. pmc Sleep duration as a risk factor for diabetes incidence in a large U.S. sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, 1051 Riverside Drive, Mailbox 2, New York, NY 10032, USA
    Sleep 30:1667-73. 2007
    ..No plausible mechanism has been identified by which long sleep duration could lead to diabetes...
  16. pmc Temporal association of cannabis use with symptoms in individuals at clinical high risk for psychosis
    Cheryl M Corcoran
    Columbia University, Department of Psychiatry, New York, NY, United States
    Schizophr Res 106:286-93. 2008
    ..Cannabis use is reported to increase the risk for psychosis, but no prospective study has longitudinally examined drug use and symptoms concurrently in clinical high risk cases...
  17. doi request reprint Olfaction and cognition in schizophrenia: sex matters
    Dolores Malaspina
    Institute for Social and Psychiatric Initiatives, New York University School of Medicine, 500 1st Ave, NBV 22N14, New York, NY 10016, USA
    J Neuropsychiatry Clin Neurosci 24:165-75. 2012
    ..These findings indicate significant sex differences in olfactory processing in schizophrenia. Combining the sexes in research analyses may obscure important differences...
  18. pmc Earlier parental set bedtimes as a protective factor against depression and suicidal ideation
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10032, USA
    Sleep 33:97-106. 2010
    ..Depression in an adolescent can affect his/her chosen bedtime, but it is less likely to affect a parent's chosen set bedtime which can establish a relatively stable upper limit that can directly affect sleep duration...
  19. pmc Later paternal age and sex differences in schizophrenia symptoms
    Paul J Rosenfield
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10019, USA
    Schizophr Res 116:191-5. 2010
    ..This study examined if PARS exhibits the symptom profile and sex differences that are consistently observed for schizophrenia in general, wherein males have an earlier onset age and more severe negative symptoms than females...
  20. pmc Effect of socioeconomic status and parents' education at birth on risk of schizophrenia in offspring
    Cheryl Corcoran
    Dept of Psychiatry, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 2, New York, NY 10032, USA
    Soc Psychiatry Psychiatr Epidemiol 44:265-71. 2009
    ..Instead, a modest increase in risk for schizophrenia was observed only for those born at the bottom of the social ladder...
  21. doi request reprint Prenatal stress and affective disorders in a population birth cohort
    Karine Kleinhaus
    Departments of Psychiatry, New York University School of Medicine, New York, NY, USA
    Bipolar Disord 15:92-9. 2013
    ..We examined the relationship of the timing of an acute psychosocial threat during pregnancy to the incidence of affective disorders in offspring using data from a large birth cohort...
  22. pmc Catatonic schizophrenia: a cohort prospective study
    Karine Kleinhaus
    Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Schizophr Bull 38:331-7. 2012
    ..This study is the first to describe catatonia using prospectively collected data and to examine how catatonic schizophrenia differs from, or resembles, other types of schizophrenia...
  23. pmc Olfactory acuity is associated with mood and function in a pilot study of stable bipolar disorder patients
    Caitlin Hardy
    Department of Psychiatry, New York University NYU School of Medicine, New York, NY, USA
    Bipolar Disord 14:109-17. 2012
    ..Olfactory dysfunction is described in several neuropsychiatric disorders but there is little research on olfactory processing in bipolar disorder...
  24. pmc The factorial structure of the schedule for the deficit syndrome in schizophrenia
    David Kimhy
    Department of Psychiatry, Box 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 32:274-8. 2006
    ..The mean severity of symptoms was 2.25 (S.D. = 1.06). We discuss possible links between the obtained factors and putative neurobiological mechanisms, as well as directions for future research...
  25. pmc Maternal household crowding during pregnancy and the offspring's risk of schizophrenia
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Schizophr Res 86:23-9. 2006
    ..We tested the hypothesis that a similar link is present in humans...
  26. pmc Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Cognitive Neuroscience, 1051 Riverside Drive, Unit 74, New York, NY 10032, USA
    Sleep 33:956-61. 2010
    ..No previous published population studies have examined the longitudinal relationship between sleep duration and high cholesterol...
  27. pmc Theory of Mind in patients at clinical high risk for psychosis
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 131:11-7. 2011
    ..As capacity for ToM normally advances with brain maturation, research on ToM in individuals at heightened clinical risk for psychosis may reveal developmental differences independent of disease based differences...
  28. ncbi request reprint Validity of a 'proxy' for the deficit syndrome derived from the Positive And Negative Syndrome Scale (PANSS)
    Raymond R Goetz
    Columbia University, Department of Psychiatry, New York State Psychiatric Institute, Research Foundation for Mental Hygiene, Schizophrenia Research Unit, New York 10032, United States
    Schizophr Res 93:169-77. 2007
    ..Further study is indicated before the PDS as extracted from the PANSS can be used in lieu of the SDS for identifying patients with this syndrome...
  29. ncbi request reprint Olfactory identification and WAIS-R performance in deficit and nondeficit schizophrenia
    Regine Anna Seckinger
    New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
    Schizophr Res 69:55-65. 2004
    ..If so, then the relationship of University of Pennsylvania Smell Identification Test (UPSIT) scores with other neurocognitive measures in DS patients may point to the neural substrate of the deficit syndrome...
  30. pmc Trajectory to a first episode of psychosis: a qualitative research study with families
    Cheryl Corcoran
    Department of Psychiatry New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
    Early Interv Psychiatry 1:308-15. 2007
    ..Qualitative research methods can be used to begin to elucidate the temporal unfolding of symptoms leading to a first episode of psychosis, and its impact on families...
  31. doi request reprint Insomnia and sleep duration as mediators of the relationship between depression and hypertension incidence
    James E Gangwisch
    Division of Cognitive Neuroscience, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Hypertens 23:62-9. 2010
    ..No previous published population studies have examined whether insomnia and sleep duration mediate the relationship between depression and hypertension incidence...
  32. ncbi request reprint Etiological heterogeneity and intelligence test scores in patients with schizophrenia
    Rachel Wolitzky
    Department of Medical Genetics, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Exp Neuropsychol 28:167-77. 2006
    ..Overall, the results suggest that sporadic patients have better perceptual-organizational skills and faster speed of processing...
  33. ncbi request reprint Catatonia in DSM-5
    Rajiv Tandon
    Department of Psychiatry, University of Florida Medical School, Gainesville, FL, USA
    Schizophr Res 150:26-30. 2013
    ..These changes should improve the consistent recognition of catatonia across the range of psychiatric disorders and facilitate its specific treatment...
  34. ncbi request reprint Advancing paternal age and autism
    Abraham Reichenberg
    Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Gen Psychiatry 63:1026-32. 2006
    ..Maternal and paternal ages are associated with neurodevelopmental disorders...
  35. pmc Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders
    Scott A Schobel
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York, USA
    Arch Gen Psychiatry 66:938-46. 2009
    ..Because schizophrenia and related disorders have a chronic time course and subtle histopathology, it is difficult to identify which brain regions are differentially targeted...
  36. pmc Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findings
    Mary C Perrin
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, 10032, USA
    Schizophr Res 90:251-4. 2007
    ..We observed an increased incidence of schizophrenia in offspring of parents who were dry cleaners (RR=3.4, 95% CI, 1.3-9.2, p=0.01). Tetrachloroethylene exposure warrants further investigation as a risk factor for schizophrenia...
  37. pmc Neuronal generator patterns of olfactory event-related brain potentials in schizophrenia
    Jürgen Kayser
    Division of Cognitive Neuroscience, New York State Psychiatric Institute, New York, New York 10032, USA
    Psychophysiology 47:1075-86. 2010
    ..N1 sink and P2 source were markedly reduced in patients for high intensity stimuli, providing further neurophysiological evidence of olfactory dysfunction in schizophrenia...
  38. pmc Olfactory deficits, cognition and negative symptoms in early onset psychosis
    Cheryl Corcoran
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 80:283-93. 2005
    ..However, smell identification has not been examined in adolescents with early onset psychosis, wherein diagnosis is often obscure, and there are few prognostic predictors...
  39. ncbi request reprint Does unwantedness of pregnancy predict schizophrenia in the offspring? Findings from a prospective birth cohort study
    Daniel B Herman
    New York State Psychiatric Institute, New York, NY, USA
    Soc Psychiatry Psychiatr Epidemiol 41:605-10. 2006
    ..We sought to replicate (or refute) a previous report of an association between unwantedness of a pregnancy and the risk of schizophrenia in the offspring...
  40. pmc Childhood trauma and prodromal symptoms among individuals at clinical high risk for psychosis
    Judy L Thompson
    Columbia University, Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 108:176-81. 2009
    ..However, little is known about the prevalence of childhood trauma and its relationship to attenuated positive and other symptoms in individuals at heightened clinical risk for psychosis...
  41. doi request reprint Older paternal age strongly increases the morbidity for schizophrenia in sisters of affected females
    Mary Perrin
    Department of Psychiatry, New York University School of Medicine, New York, New York, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1329-35. 2010
    ..The authors speculate that the hypothesized paternally expressed genes on the X chromosome might play some role in these observations...
  42. pmc Stigma in families of individuals in early stages of psychotic illness: family stigma and early psychosis
    Celine Wong
    Department of Psychiatry, Columbia University, New York, New York, USA
    Early Interv Psychiatry 3:108-15. 2009
    ..These forms of stigma may present a barrier to help seeking. However, little is known about stigma in the early stages of evolving psychotic disorder...
  43. pmc Anterior hippocampal and orbitofrontal cortical structural brain abnormalities in association with cognitive deficits in schizophrenia
    Scott A Schobel
    Center for Prevention and Evaluation, New York State Psychiatric Institute, USA
    Schizophr Res 114:110-8. 2009
    ..As an exploratory study goal, we investigated the relation of neurocognition to brain structure in schizophrenia patients...
  44. pmc Paternal age and risk of schizophrenia in adult offspring
    Alan S Brown
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
    Am J Psychiatry 159:1528-33. 2002
    ..The study examined the relation between paternal age at the time of birth and risk of schizophrenia in the adult offspring...
  45. pmc Emotion awareness and regulation in individuals with schizophrenia: Implications for social functioning
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Psychiatry Res 200:193-201. 2012
    ..The present study highlights the importance of emotion awareness and regulation in schizophrenia, pointing to their substantial influence on social functioning above and beyond the impact of neurocognitive functioning...
  46. pmc Schizophrenia comorbid with panic disorder: evidence for distinct cognitive profiles
    Erica Kirsten Rapp
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Psychiatry Res 197:206-11. 2012
    ..These data offer further support for a definable panic-psychosis subtype and suggest new etiological pathways for future research...
  47. ncbi request reprint Trail making and olfaction in schizophrenia: implications for processing speed
    Nora Goudsmit
    Department of Medical Genetics, New York State Psychiatric Institute, New York, NY 10032, USA
    CNS Spectr 9:344-9, 356. 2004
    ..Previous research has established a relationship between smell identification deficits (SID) and particular aspects of cognitive function among patients with schizophrenia...
  48. pmc Concurrent measurement of "real-world" stress and arousal in individuals with psychosis: assessing the feasibility and validity of a novel methodology
    David Kimhy
    Department of Psychiatry, Box 55, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 36:1131-9. 2010
    ..Our aim is to the test the feasibility and validity of a novel methodology designed to measure concurrent stress and arousal in individuals with psychosis during "real-world" daily functioning...
  49. pmc Computerized experience sampling method (ESMc): assessing feasibility and validity among individuals with schizophrenia
    David Kimhy
    Department of Psychiatry, Unit 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    J Psychiatr Res 40:221-30. 2006
    ..The authors discuss the potential applications of combining ESMc with ambulatory physiological measures...
  50. pmc Odor identification, eye tracking and deficit syndrome schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 51:809-15. 2002
    ..Deficit syndrome (DS) schizophrenia patients have smooth pursuit eye movement (SPEM) dysfunction. We examined if they also had smell identification deficits, since social affiliation is related to olfaction in other mammals...
  51. ncbi request reprint A brief smell identification test discriminates between deficit and non-deficit schizophrenia
    Nora Goudsmit
    New York State Psychiatric Institute and Columbia University Departments of Psychiatry and the College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 120:155-64. 2003
    ..The results of this study support the utility of the B-SIT for schizophrenia research and highlight the robustness of the relationship between SID and social dysfunction in schizophrenia...
  52. ncbi request reprint Assessing the heterogeneity of aggressive behavior traits: exploratory and confirmatory analyses of the reactive and instrumental aggression Personality Assessment Inventory (PAI) scales
    Daniel Antonius
    New York University School of Medicine, New York, NY, USA
    Violence Vict 28:587-601. 2013
    ..Overall, the exploratory and confirmatory analyses supported the existence of two latent PAI factor structures, which delineate personality traits related to reactive and instrumental aggression...
  53. pmc Sleep duration and risk for hypertension in women: results from the nurses' health study
    James E Gangwisch
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Hypertens 26:903-11. 2013
    ..Acute sleep restriction has been shown to increase blood pressure and sympathetic nervous system activity...
  54. ncbi request reprint A model of verbal memory impairments in schizophrenia: two systems and their associations with underlying cognitive processes and clinical symptoms
    Gildas Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 35:133-42. 2005
    ..The results have been reported in previous papers. In this paper we show how all these data could be integrated into a consistent pattern of associations...
  55. pmc Comparable family burden in families of clinical high-risk and recent-onset psychosis patients
    Celine Wong
    Department of Psychiatry, Columbia University, New York, USA
    Early Interv Psychiatry 2:256-61. 2008
    ..In this exploratory study, we examined the extent of burden reported by families of patients during a putative prodromal period and in the after-math of psychosis onset...
  56. pmc White matter integrity and lack of insight in schizophrenia and schizoaffective disorder
    Daniel Antonius
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Schizophr Res 128:76-82. 2011
    ..Despite the importance of this issue, the neural correlates of insight deficits in schizophrenia remain poorly understood...
  57. ncbi request reprint Racial and ethnic effects on psychotic psychiatric diagnostic changes from admission to discharge: a retrospective chart review
    Deidre M Anglin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychiatry 69:464-9. 2008
    ..We examined the frequency upon admission and at discharge and further explored the pattern of diagnostic changes that occurred by racial/ethnic group...
  58. pmc The Jerusalem Perinatal Study cohort, 1964-2005: methods and a review of the main results
    Susan Harlap
    Department of Epidemiology, Mailman School of Public Health, New York 10032, USA
    Paediatr Perinat Epidemiol 21:256-73. 2007
    ..Characteristics of this unique population are shown. Findings from the study are reviewed and a list of references is provided. The cohorts provide a unique source of data for a wide variety of studies...
  59. pmc Delusions in individuals with schizophrenia: factor structure, clinical correlates, and putative neurobiology
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Psychopathology 38:338-44. 2005
    ..Our goal is to examine the factor structure of delusions in antipsychotic-free individuals with diagnoses of schizophrenia/schizoaffective disorder...
  60. doi request reprint Critical periods and the developmental origins of disease: an epigenetic perspective of schizophrenia
    Mary Perrin
    New York University School of Medicine, Social and Psychiatric Initiatives InSPIRES, New York, New York 10016, USA
    Ann N Y Acad Sci 1204:E8-13. 2010
    ..This introduction considers the possibility that epigenetic change that may occur as paternal age advances or during fetal adversity may be causally related to the susceptibility for schizophrenia...
  61. pmc Avolition and expressive deficits capture negative symptom phenomenology: implications for DSM-5 and schizophrenia research
    Julie W Messinger
    Institute for Social and Psychiatric Initiatives InSPIRES, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Clin Psychol Rev 31:161-8. 2011
    ..We recommend that these two domains should be assessed as separate dimensions in the DSM-5 criteria...
  62. pmc Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia
    Mary C Perrin
    Department of Psychiatry, School of Medicine, New York University, New York, NY, USA
    Schizophr Bull 33:1270-3. 2007
    ..This article will discuss parental imprinting on the autosomal and X chromosomes and the alterations in epigenetic regulation that may lead to such errors...
  63. ncbi request reprint Paternal age and preeclampsia
    Susan Harlap
    Department of Obstetrics and Gynecology and Kaplan Cancer Center, New York University School of Medicine, New York, NY 10016, USA
    Epidemiology 13:660-7. 2002
    ..Paternal aging is associated with premeiotic damage to spermatogonia, a mechanism by which new point mutations are introduced into the gene pool. We hypothesized that paternal age might contribute to preeclampsia...
  64. ncbi request reprint Suicide attempts in schizophrenia: the role of command auditory hallucinations for suicide
    Jill M Harkavy-Friedman
    New York State Psychiatric Institute, New York, N Y, USA
    J Clin Psychiatry 64:871-4. 2003
    ..We examined the relationship between CAHS and demographic and clinical variables. We also investigated the relationship between CAHS and suicide attempts...
  65. ncbi request reprint Ethnicity effects on clinical diagnoses compared to best-estimate research diagnoses in patients with psychosis: a retrospective medical chart review
    Deidre M Anglin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    J Clin Psychiatry 69:941-5. 2008
    ..Ethnicity effects on diagnoses are frequently reported and have variably been attributed to diagnostic biases versus ethnic differences in environmental exposures, and other factors...
  66. pmc Effects of excessive glucocorticoid receptor stimulation during early gestation on psychomotor and social behavior in the rat
    Karine Kleinhaus
    Department of Psychiatry New York University Medical Center, New York, NY, USA
    Dev Psychobiol 52:121-32. 2010
    ..Moreover, some of these deficits may be mediated by alterations in postnatal maternal behavior and physiology produced by early gestational exposure to excess glucocorticoids...
  67. ncbi request reprint The stress cascade and schizophrenia: etiology and onset
    Cheryl Corcoran
    New York State Psychiatric Institute Columbia University, New York, NY 10032, USA
    Schizophr Bull 29:671-92. 2003
    ....
  68. pmc rTMS strategies for the study and treatment of schizophrenia: a review
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, Cabrini Hospital, Mt Sinai Medical Center, New York, NY 10032, USA
    Int J Neuropsychopharmacol 11:563-76. 2008
    ..Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy...
  69. pmc A qualitative research study of the evolution of symptoms in individuals identified as prodromal to psychosis
    Cheryl Corcoran
    New York State Psychiatric Institute Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatr Q 74:313-32. 2003
    ..Although preliminary, these results suggest that a trajectory of change in personality, relationships, and behavior from an essentially normal baseline may be consistent with increased risk for psychosis among prodromal adolescents...
  70. pmc Self-reported coping strategies in families of patients in early stages of psychotic disorder: an exploratory study
    Ruth Gerson
    Department of Psychiatry, New York University, New York, New York, USA
    Early Interv Psychiatry 5:76-80. 2011
    ..g. reinterpretation) and potentially maladaptive 'avoidant' strategies (denial/disengagement, use of alcohol and drugs). Little is known about coping strategies used by families of individuals with incipient or emergent psychosis...
  71. ncbi request reprint Clinical and cognitive factors associated with verbal memory task performance in patients with schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Am J Psychiatry 158:758-64. 2001
    ..They wished to determine the specific contribution of each of these factors to various types of memory impairment...
  72. pmc Twin pregnancy and the risk of schizophrenia
    K Kleinhaus
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, United States
    Schizophr Res 105:197-200. 2008
    ..Previous studies report contradictory findings on the risk for schizophrenia in twins...
  73. pmc Schizophrenia and birthplace of paternal and maternal grandfather in the Jerusalem perinatal cohort prospective study
    S Harlap
    Department of Psychiatry, New York University School of Medicine, NY 10016, USA
    Schizophr Res 111:23-31. 2009
    ..Such a locus, if it exists, might involve the X chromosome...
  74. pmc High-frequency prefrontal repetitive transcranial magnetic stimulation for the negative symptoms of schizophrenia: a case series
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, New York, NY, USA
    J ECT 27:11-7. 2011
    ..This pilot study assessed higher doses of rTMS and assessed particular demographic factors that may influence treatment response...
  75. pmc Multivoxel proton MR spectroscopy used to distinguish anterior cingulate metabolic abnormalities in patients with schizophrenia
    Caitlin J Hardy
    Department of Radiology, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
    Radiology 261:542-50. 2011
    ..To test the hypothesis that anterior cingulate cortex (ACC) subregions in patients with schizophrenia are metabolically different from those in healthy control subjects...
  76. ncbi request reprint Anxiety and substance use comorbidity among inpatients with schizophrenia
    Renee D Goodwin
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 43, New York 10032, USA
    Schizophr Res 61:89-95. 2003
    ..To determine the association between lifetime anxiety symptoms and anxiety disorders and substance use disorders among patients with schizophrenia...
  77. pmc Prodromal interventions for schizophrenia vulnerability: the risks of being "at risk"
    Cheryl Corcoran
    New York State Psychiatric Institute and the Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, United States
    Schizophr Res 73:173-84. 2005
    ....
  78. pmc Revisiting the backward masking deficit in schizophrenia: individual differences in performance and modeling with transcranial magnetic stimulation
    Bruce Luber
    Brain Stimulation and Therapeutic Modulation Division, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 62:793-9. 2007
    ..In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically...
  79. ncbi request reprint Inadequate sleep as a risk factor for obesity: analyses of the NHANES I
    James E Gangwisch
    Mailman School of Public Health, Department of Epidemiology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Sleep 28:1289-96. 2005
    ..This study examines cross-sectional and longitudinal data from a large United States sample to determine whether sleep duration is associated with obesity and weight gain...
  80. ncbi request reprint The concept of population prevention: application to schizophrenia
    Ramin Mojtabai
    Department of Psychiatry, Columbia University, USA
    Schizophr Bull 29:791-801. 2003
    ..The article concludes that population and high-risk prevention strategies can be complementary and that it may be feasible and appropriate to use them in combination...
  81. ncbi request reprint Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey
    James E Gangwisch
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Hypertension 47:833-9. 2006
    ..Short sleep duration could, therefore, be a significant risk factor for hypertension...
  82. pmc Family history of affective illness in schizophrenia patients: symptoms and cognition
    Deidre Anglin
    Department of Psychology, The City College and The Graduate Center, City University of New York, United States
    Schizophr Res 110:24-7. 2009
    ..Schizophrenia patients with a family history of affective disorder may be a distinct subtype in the group of schizophrenias and may be biologically more similar to patients with serious affective disorder...
  83. ncbi request reprint Brain event-related potentials (ERPs) in schizophrenia during a word recognition memory task
    J Kayser
    Department of Biopsychology, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Psychophysiol 34:249-65. 1999
    ..These findings suggest that impaired word recognition in schizophrenia may arise from a left lateralized deficit at an early stage of processing, beginning at 200-300 ms after word onset...
  84. ncbi request reprint Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies
    L S Kegeles
    Department of Psychiatry, Columbia University, New York, NY, USA
    Psychiatry Res 98:163-75. 2000
    ..The preliminary finding of a lateralized abnormality in Glx is consistent with postmortem findings of asymmetric neurochemical temporal lobe abnormalities in schizophrenia...
  85. pmc Visual form perception: a comparison of individuals at high risk for psychosis, recent onset schizophrenia and chronic schizophrenia
    D Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Schizophr Res 97:25-34. 2007
    ..These deficits are discussed in the context of the putative neurobiological underpinnings of visual deficits and the developmental pathophysiology of psychosis in schizophrenia...
  86. ncbi request reprint Depression, psychomotor retardation, negative symptoms, and memory in schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Neuropsychiatry Neuropsychol Behav Neurol 13:177-83. 2000
    ..The purpose of this study was to examine the relations between depression, psychomotor retardation, and negative symptoms in schizophrenia as well as the specific contribution of each of these factors to memory impairment...
  87. ncbi request reprint Paternal age and spontaneous abortion
    K Kleinhaus
    Epidemiology Department, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Obstet Gynecol 108:369-77. 2006
    ..To evaluate the influence of paternal age upon spontaneous abortion...
  88. ncbi request reprint NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees
    C A Kaufmann
    College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Med Genet 81:282-9. 1998
    ....
  89. pmc The relationship of social function to depressive and negative symptoms in individuals at clinical high risk for psychosis
    C M Corcoran
    Centre of Prevention and Evaluation, Department of Psychiatry, New York State Psychiatric Institute at Columbia University, New York, NY 10032, USA
    Psychol Med 41:251-61. 2011
    ..It is unclear if social symptoms in clinical high-risk patients reflect depressive symptoms or are a manifestation of negative symptoms...
  90. ncbi request reprint Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium
    S V Faraone
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, USA
    Am J Med Genet 81:290-5. 1998
    ..4, P = .0004) and its neighbor, D10S582 (NPL Z = 3.2, P = .0006)...
  91. ncbi request reprint Positive symptomatology and source-monitoring failure in schizophrenia--an analysis of symptom-specific effects
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychiatry Res 95:119-31. 2000
    ..However, this finer-grained analysis revealed that the three of them were in fact associated with hallucinations and/or delusions. On the other hand, thought disorganisation appeared to be independent from these mechanisms...
  92. pmc Acute maternal stress in pregnancy and schizophrenia in offspring: a cohort prospective study
    D Malaspina
    Department of Psychiatry, New York University School of Medicine, New York, NY, USA
    BMC Psychiatry 8:71. 2008
    ..We aimed to describe the consequence of an acute maternal stress, through a follow-up of offspring whose mothers were pregnant during the Arab-Israeli war of 1967. A priori, we focused on gestational month and offspring's sex...
  93. doi request reprint Psychiatric assessment of aggressive patients: a violent attack on a resident
    Daniel Antonius
    New York University School of Medicine, New York, NY 10016, USA
    Am J Psychiatry 167:253-9. 2010
    ..This report illustrates common deficiencies in the prevention of violence on inpatient psychiatric units and in the reporting and response to an assault, and has implications for residency and clinician training...
  94. ncbi request reprint Memory and schizophrenia: differential link of processing speed and selective attention with two levels of encoding
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute and Creedmoor Psychiatric Center, New York, NY, USA
    J Psychiatr Res 34:121-7. 2000
    ..Selective attention only contributed to the superficial encoding processes. Thus, slowing of processing speed in schizophrenia seems to be more crucial for memory performance, since it affects memory in a pervasive way...
  95. ncbi request reprint Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7)
    R Freedman
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Med Genet 105:20-2. 2001
    ..Replication of this result was found in an additional set of families. The results support this region as a chromosomal location involved in the genetic transmission of schizophrenia...
  96. ncbi request reprint Opposite links of positive and negative symptomatology with memory errors in schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Psychiatry Res 88:15-24. 1999
    ..Fewer errors were specifically associated with more affective flattening, alogia and anhedonia, whereas avolition was entirely unrelated to them...
  97. pmc Human hippocampal subfields in young adults at 7.0 T: feasibility of imaging
    Vasthie Prudent
    Departments of Radiology and Psychiatry, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
    Radiology 254:900-6. 2010
    ....
  98. ncbi request reprint Preventing clinical deterioration in the course of schizophrenia: the potential for neuroprotection
    Jeffrey A Lieberman
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, USA
    J Clin Psychiatry 67:983-90. 2006
  99. ncbi request reprint Schizophrenia: a neurodevelopmental or a neurodegenerative disorder
    Dolores Malaspina
    Department of Psychiatry and New York State Psychiatric Institute, Columbia University, New York, USA
    J Clin Psychiatry 67:e07. 2006
    ....
  100. ncbi request reprint A.E. Bennett Research Award. Prenatal rubella, premorbid abnormalities, and adult schizophrenia
    A S Brown
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 49:473-86. 2001
    ..CONCLUSIONS: These findings link a known prenatal exposure, a deviant neurodevelopmental trajectory in childhood and adolescence, and SSP in adulthood within the same individuals...
  101. ncbi request reprint Growth and schizophrenia: aetiology, epidemiology and epigenetics
    D Malaspina
    Department of Psychiatry, New York University School ofMedicine, New York, NY 10016, USA
    Novartis Found Symp 289:196-203; discussion 203-7, 238-40. 2008
    ..These findings suggest exciting new directions for research into the aetiology of schizophrenia...