L H Lumey

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Cohort profile: the Dutch Hunger Winter families study
    L H Lumey
    Department of Epidemiology Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Int J Epidemiol 36:1196-204. 2007
  2. doi request reprint Association between type 2 diabetes and prenatal exposure to the Ukraine famine of 1932-33: a retrospective cohort study
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands Electronic address
    Lancet Diabetes Endocrinol 3:787-94. 2015
  3. doi request reprint No relation between coronary artery disease or electrocardiographic markers of disease in middle age and prenatal exposure to the Dutch famine of 1944-5
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Heart 98:1653-9. 2012
  4. pmc Adult global DNA methylation in relation to pre-natal nutrition
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA
    Int J Epidemiol 41:116-23. 2012
  5. pmc Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 89:1737-43. 2009
  6. pmc Prenatal famine and adult health
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Annu Rev Public Health 32:237-62. 2011
  7. pmc Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19
    Elmar W Tobi
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    PLoS ONE 7:e37933. 2012
  8. ncbi request reprint The epigenome: archive of the prenatal environment
    Bastiaan T Heijmans
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Epigenetics 4:526-31. 2009
  9. pmc Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction
    Rudolf P Talens
    Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Epidemiol 41:106-15. 2012
  10. doi request reprint Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
    Elmar W Tobi
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Epidemiol 44:1211-23. 2015

Detail Information

Publications22

  1. ncbi request reprint Cohort profile: the Dutch Hunger Winter families study
    L H Lumey
    Department of Epidemiology Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Int J Epidemiol 36:1196-204. 2007
  2. doi request reprint Association between type 2 diabetes and prenatal exposure to the Ukraine famine of 1932-33: a retrospective cohort study
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands Electronic address
    Lancet Diabetes Endocrinol 3:787-94. 2015
    ..We used data from during the man-made Ukrainian famine of 1932-33 to examine the association between restricted nutrition in early gestation and type 2 diabetes in offspring in later life...
  3. doi request reprint No relation between coronary artery disease or electrocardiographic markers of disease in middle age and prenatal exposure to the Dutch famine of 1944-5
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Heart 98:1653-9. 2012
    ..For further evaluation, we examined multiple cardiac risk markers in adult men and women with prenatal exposure to the Dutch famine of 1944-5...
  4. pmc Adult global DNA methylation in relation to pre-natal nutrition
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA
    Int J Epidemiol 41:116-23. 2012
    ..There have been no studies to date of the relation between pre-natal famine and overall global DNA methylation in adulthood...
  5. pmc Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 89:1737-43. 2009
    ..Many studies in humans have related birth weight to lipid profiles in adulthood. Fewer have estimated associations directly attributable to maternal nutrition during pregnancy...
  6. pmc Prenatal famine and adult health
    L H Lumey
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Annu Rev Public Health 32:237-62. 2011
    ..Much progress can be made if current separate studies are further analyzed with comparable definitions of exposures and outcomes and using common analytic strategies...
  7. pmc Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19
    Elmar W Tobi
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    PLoS ONE 7:e37933. 2012
    ..5 standard deviations relative to the variation in the population. Our analyses suggest that environmental and genetic factors could have independent and additive similarly sized effects on DNA methylation at the same regulatory site...
  8. ncbi request reprint The epigenome: archive of the prenatal environment
    Bastiaan T Heijmans
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Epigenetics 4:526-31. 2009
    ..Well-designed epigenome-wide studies will be crucial in creating a catalog of epigenomic regions that are sensitive to the prenatal environment to evaluate developmental influences on common human disease...
  9. pmc Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction
    Rudolf P Talens
    Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Epidemiol 41:106-15. 2012
    ..Methylation at IL10, LEP, ABCA1, IGF2, INS and GNASAS was measured in DNA extracted from leucocytes using mass spectrometry...
  10. doi request reprint Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
    Elmar W Tobi
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Epidemiol 44:1211-23. 2015
    ..Human studies have concentrated on the effects of nutrition during early gestation. Lacking in humans is an epigenome-wide association study of DNA methylation in relation to perturbations in nutrition across all gestation periods...
  11. pmc Persistent epigenetic differences associated with prenatal exposure to famine in humans
    Bastiaan T Heijmans
    Departments of Molecular Epidemiology, Medical Statistics, and Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands
    Proc Natl Acad Sci U S A 105:17046-9. 2008
    ..These data are the first to contribute empirical support for the hypothesis that early-life environmental conditions can cause epigenetic changes in humans that persist throughout life...
  12. ncbi request reprint Genital herpes simplex virus infection and perinatal transmission of human immunodeficiency virus
    Katherine T Chen
    Department of Obstetrics and Gynecology, Columbia University, Sergievsky Center and Harlem Hospital Center, New York, New York 10032, USA
    Obstet Gynecol 106:1341-8. 2005
    ..To assess the risk of perinatal human immunodeficiency virus (HIV) transmission in HIV-infected women clinically diagnosed with genital herpes simplex virus (HSV) infection during pregnancy...
  13. ncbi request reprint Chemoprevention strategies for prostate cancer
    Maarten C Bosland
    Department of Environmental Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Eur J Cancer Prev 11:S18-27. 2002
    ..Such trials are an essential step in the development of antiprostate cancer chemoprevention agents...
  14. ncbi request reprint Chemoprevention trials in men with prostate-specific antigen failure or at high risk for recurrence after radical prostatectomy: Application to efficacy assessment of soy protein
    M C Bosland
    Department of Environmental Medicine New York University School of Medicine, New York, New York 10016, USA
    Urology 57:202-4. 2001
    ..The strengths and limitations of these designs are discussed and interim experience using studies with soy protein as the intervention agent are summarized...
  15. ncbi request reprint Adherence to a low-fat diet in men with prostate cancer
    Lilli B Link
    Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    Urology 64:970-5. 2004
    ..To design preventive and therapeutic interventions, it is important to know whether men will adhere to these nutritional recommendations, particularly when motivated by the diagnosis of prostate cancer...
  16. ncbi request reprint Exposure to famine during gestation, size at birth, and blood pressure at age 59 y: evidence from the Dutch Famine
    Aryeh D Stein
    Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Eur J Epidemiol 21:759-65. 2006
    ..08) blood pressure and with hypertension prevalence (odds ratio 1.44; 95% CI 1.04, 2.00; p < 0.05) in age- and sex-adjusted models. Exposure to famine during gestation may predispose to the development of hypertension in middle age...
  17. pmc Acute undernutrition is not associated with excess of females at birth in humans: the Dutch hunger winter
    Aryeh D Stein
    Department of International Health, Rollins School of Public Health, 1518 Clifton Road, NE Emory University, Atlanta, GA 30322, USA
    Proc Biol Sci 271:S138-41. 2004
    ..31, 95% CI 1.09-1.58; p = 0.004) of male offspring. Our data do not provide any support for acute and severe maternal undernutrition as a trigger for an increase in female conceptions or in male foetal deaths in human populations...
  18. ncbi request reprint Intrauterine famine exposure and body proportions at birth: the Dutch Hunger Winter
    Aryeh D Stein
    Rollins School of Public Health, Emory University, Atlanta, GA, USA
    Int J Epidemiol 33:831-6. 2004
    ..Expected short-term effects include changes in body size and proportions at birth. The specific responses of fetal growth to acute undernutrition at varying points in pregnancy are still unclear...
  19. ncbi request reprint Energy restriction early in life and colon carcinoma risk: results of The Netherlands Cohort Study after 7.3 years of follow-up
    Miranda J M Dirx
    Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Cancer 97:46-55. 2003
    ..This study evaluated the effects of severe undernutrition during adolescence and subsequent colon carcinoma risk...
  20. ncbi request reprint A fingerprint characteristic associated with the early prenatal environment
    Henry S Kahn
    Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Hum Biol 20:59-65. 2008
    ..Fingerprint RC differences observed in postnatal life may be useful in the study of metabolic or anatomic programming related to the early prenatal environment...
  21. ncbi request reprint Anthropometric measures in middle age after exposure to famine during gestation: evidence from the Dutch famine
    Aryeh D Stein
    Rollins School of Public Health, Emory University, Atlanta, GA, USA
    Am J Clin Nutr 85:869-76. 2007
    ..Few studies in humans have related maternal undernutrition to the size of the adult offspring...
  22. ncbi request reprint Prospective risk of fetal death in singleton, twin, and triplet gestations: implications for practice
    Bronwen Kahn
    Department of Obstetrics and Gynecology, University of Colorado, Denver, Colorado, USA
    Obstet Gynecol 102:685-92. 2003
    ..To evaluate the prospective risk of fetal death in singleton, twin, and triplet pregnancies and to compare this risk with fetal and neonatal death rates...