Research Topics
| Sarah LisanbySummaryAffiliation: Columbia University Country: USA Publications
Research Grants
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Detail Information
Publications
The effects of electroconvulsive therapy on memory of autobiographical and public eventsS H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032, USA
Arch Gen Psychiatry 57:581-90. 2000..This study examined the short- and long-term effects of differing forms of ECT on memory of personal and impersonal (public) events...
New developments in electroconvulsive therapy and magnetic seizure therapySarah H Lisanby
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York City, USA
CNS Spectr 8:529-36. 2003..This article reviews the experience to date with MST, and places this work in the broader context of other means of optimizing convulsive therapy in the treatment of depression...
Safety and feasibility of magnetic seizure therapy (MST) in major depression: randomized within-subject comparison with electroconvulsive therapySarah H Lisanby
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Neuropsychopharmacology 28:1852-65. 2003..Magnetic seizure induction in patients with depression is feasible, and appears to have a superior acute side effect profile than ECT. Future research will be needed to establish whether MST has antidepressant efficacy...
Neurophysiological characterization of magnetic seizure therapy (MST) in non-human primatesSarah H Lisanby
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
Suppl Clin Neurophysiol 56:81-99. 2003
Update on magnetic seizure therapy: a novel form of convulsive therapySarah H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, Columbia University, New York, New York 10032, USA
J ECT 18:182-8. 2002....
Applications of TMS to therapy in psychiatrySarah H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, New York 10032, USA
J Clin Neurophysiol 19:344-60. 2002..Current challenges in the field include determining how to enhance the efficacy of TMS in these disorders and how to identify patients for whom TMS may be efficacious...
Animal models of the mechanisms of action of repetitive transcranial magnetic stimulation (RTMS): comparisons with electroconvulsive shock (ECS)S H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
Depress Anxiety 12:178-87. 2000..Finally, rTMS is emerging as yet another intervention, like ECS and other antidepressants, that can regulate gene expression and may have an impact on neuronal viability and synaptic plasticity...
ECT in the treatment of status epilepticusS H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032 2695, USA
J ECT 17:210-5. 2001..Owing to its potent anticonvulsant actions, electroconvulsive therapy (ECT) has been proposed as an intervention for treatment-resistant seizure disorders...
ECT use in unipolar and bipolar depressionSmita Agarkar
Department of Psychiatry, Weill Cornell Medical College, New York, NY, USA
J ECT 28:e39-40. 2012..Few studies have compared response to electroconvulsive therapy (ECT) in depressed patients with unipolar and bipolar disorder...
A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS)ANGEL V PETERCHEV
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York, NY 10032, USA
IEEE Trans Biomed Eng 55:257-66. 2008..The technological solutions used in the cTMS prototype can expand functionality, and reduce power consumption and coil heating in TMS, enhancing its research and therapeutic applications...
Electroconvulsive therapy for depressionSarah H Lisanby
Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Dr, Unit 21, New York, NY 10032, USA
N Engl J Med 357:1939-45. 2007
Motor cortex excitability after vagus nerve stimulation in major depressionMalek Bajbouj
Department of Psychiatry, Charite Universitatsmedizin Berlin, Germany
J Clin Psychopharmacol 27:156-9. 2007..These results suggest that VNS is capable of changing motor cortical excitability in patients with depression...
Neuropathologic examination after 91 ECT treatments in a 92-year-old woman with late-onset depressionJason Scalia
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J ECT 23:96-8. 2007..Cognition in this patient was intact as indicated by a perfect score on a Mini-Mental Status Examination administered 6 days before death at the age of 92. This case adds to the considerable evidence for the safety of ECT...
Repetitive Transcranial Magnetic Stimulation (rTMS) in the treatment of panic disorder (PD) with comorbid major depressionAntonio Mantovani
Department of Psychiatry, Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 21, New York, NY 10032, USA
J Affect Disord 102:277-80. 2007..We tested whether low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) could normalize the overactivity of right frontal regions and thereby improve symptoms...
Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primatesTarique D Perera
Department of Biological Psychiatry, New York State Psychiatric Institute New York, New York 10032, USA
J Neurosci 27:4894-901. 2007..This study demonstrates that ECS is capable of inducing neurogenesis in the nonhuman primate hippocampus and supports the possibility that antidepressant interventions produce similar alterations in the human brain...
Neocortical and hippocampal neuron and glial cell numbers in the rhesus monkeyJeppe Romme Christensen
Research Laboratory for Stereology and Neuroscience, Bispebjerg University Hospital, Copenhagen, Denmark
Anat Rec (Hoboken) 290:330-40. 2007..The results are phylogenetically consistent, apart from the neuron/glia ratio, which is remarkably higher than what is found in other species...
Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatmentPhilip G Janicak
Department of Psychiatry, Rush University Medical Center, Chicago, IL 60612, USA
J Clin Psychiatry 69:222-32. 2008..We examined the acute efficacy of TMS in a randomized sham-controlled trial, under open-label conditions, and its durability of benefit...
rTMS strategies for the study and treatment of schizophrenia: a reviewArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, Cabrini Hospital, Mt Sinai Medical Center, New York, NY 10032, USA
Int J Neuropsychopharmacol 11:563-76. 2008..Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy...
Differential effects of high-dose magnetic seizure therapy and electroconvulsive shock on cognitive functionTimothy Spellman
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
Biol Psychiatry 63:1163-70. 2008..5 x seizure threshold...
The efficacy of acute electroconvulsive therapy in atypical depressionMustafa M Husain
Department of Psychiatry, University of Texas UT Southwestern Medical Center at Dallas, TX 75390 8898, USA
J Clin Psychiatry 69:406-11. 2008..This study examined the characteristics and outcomes of patients with major depressive disorder (MDD), with or without atypical features, who were treated with acute bilateral electroconvulsive therapy (ECT)...
Transcranial magnetic stimulation in the acute treatment of major depressive disorder: clinical response in an open-label extension trialDavid H Avery
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
J Clin Psychiatry 69:441-51. 2008....
Quick recovery of orientation after magnetic seizure therapy for major depressive disorderGeorge Kirov
Cardiff University, Henry Wellcome Building, Heath Park, Cardiff, UK
Br J Psychiatry 193:152-5. 2008..Its use may be justified if it produces the antidepressant effects of electroconvulsive therapy (ECT), coupled with limited cognitive side-effects...
Differential neurophysiological effects of magnetic seizure therapy (MST) and electroconvulsive shock (ECS) in non-human primatesYael M Cycowicz
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, 1051 Riverside Drive, Unit 21, New York, NY 10032, USA
Clin EEG Neurosci 39:144-9. 2008..The clinical significance of these similarities and differences awaits clinical correlation...
Repetitive Transcranial Magnetic Stimulation of the Supplementary Motor Area in the treatment of Tourette Syndrome: report of two casesAntonio Mantovani
Clin Neurophysiol 118:2314-5. 2007
Revisiting the backward masking deficit in schizophrenia: individual differences in performance and modeling with transcranial magnetic stimulationBruce Luber
Brain Stimulation and Therapeutic Modulation Division, New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 62:793-9. 2007..In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically...
Anesthetic considerations for magnetic seizure therapy: a novel therapy for severe depressionPaul F White
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9068, USA
Anesth Analg 103:76-80, table of contents. 2006..Further studies are required to evaluate the antidepressant efficacy of MST versus ECT when they are administered at comparable levels of cerebral stimulation...
Evidence for impaired cortical inhibition in patients with unipolar major depressionMalek Bajbouj
Department of Psychiatry, Charite University Medicine Berlin, Berlin, Germany
Biol Psychiatry 59:395-400. 2006..Transcranial magnetic stimulation is a useful tool for investigating central cortical inhibitory mechanisms associated with GABAergic neurotransmission in psychiatric and neurological disorders...
Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysisTal Burt
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Int J Neuropsychopharmacol 5:73-103. 2002..We also review the application of TMS in the study of the pathophysiology of psychiatric disorders and summarize studies of the safety of TMS in human subjects...
Magnetic seizure therapy improves mood in refractory major depressionMarkus Kosel
Department of Psychiatry, University Hospital Bern, Switzerland
Neuropsychopharmacology 28:2045-8. 2003..Our preliminary data support the prospect of antidepressant efficacy of MST and point to a benign cognitive side-effect profile in a patient suffering from severe treatment-resistant major depression...
Absence of histological lesions in primate models of ECT and magnetic seizure therapyAndrew J Dwork
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032, USA
Am J Psychiatry 161:576-8. 2004..The authors present preliminary findings from the first nonhuman primate neuropathological study of ECT to use perfusion fixation and adequate controls and the first to compare ECT with magnetic seizure therapy, to their knowledge...
A primate model of anterograde and retrograde amnesia produced by convulsive treatmentTammy D Moscrip
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, New York, USA
J ECT 20:26-36. 2004..This study developed and validated a cognitive battery to assess amnesia in nonhuman primates, providing new experimental paradigms for evaluating the cognitive effects of convulsive treatment...
Electroconvulsive therapy and repetitive transcranial magnetic stimulation in children and adolescents: a review and report of two cases of epilepsia partialis continuaOscar G Morales
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Box 126, New York, NY 10032 2695, USA
Child Adolesc Psychiatr Clin N Am 14:193-210, viii-ix. 2005....
Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomesLauren B Marangell
Department of Psychiatry, Baylor College of Medicine, One Baylor Plaza, BCM 350, Houston, TX 77030, USA
Biol Psychiatry 51:280-7. 2002..CONCLUSIONS: Longer-term vagus nerve stimulation treatment was associated with sustained symptomatic benefit and sustained or enhanced functional status in this naturalistic follow-up study...
Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodesZiad Nahas
Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29403, USA
J Clin Psychiatry 66:1097-104. 2005..We examined the effects of adjunctive VNS over 24 months in this cohort...
Randomized controlled trial of the cognitive side-effects of magnetic seizure therapy (MST) and electroconvulsive shock (ECS)Tammy D Moscrip
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY, USA
Int J Neuropsychopharmacol 9:1-11. 2006..Time to task completion following MST did not differ from sham. These findings suggest that MST results in a more benign acute cognitive side-effect profile than ECS in this model, consistent with initial observations with human MST...
Repetitive transcranial magnetic stimulation (rTMS) in the treatment of obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS)Antonio Mantovani
Department of Neuroscience, Section of Psychiatry, Section of Neurophysiology, Postgraduate School in Applied Neurological Sciences, Siena University, Siena, Italy
Int J Neuropsychopharmacol 9:95-100. 2006..Slow rTMS to SMA resulted in a significant clinical improvement and a normalization of the right hemisphere hyperexcitability, thereby restoring hemispheric symmetry in motor threshold...
Cortical excitability in cocaine-dependent patients: a replication and extension of TMS findingsNashaat N Boutros
Department of Psychiatry, c o VA Connecticut Healthcare System, Yale University School of Medicine, 950 Campbell Avenue, 116A West Haven, CT 06516, USA
J Psychiatr Res 39:295-302. 2005..These data support our initial finding of decreased cortical excitability in abstinent cocaine-dependent subjects. We interpret this finding as a compensatory mechanism against the stimulating and epileptogenic effects of cocaine...
Optimization of Golgi methods for impregnation of brain tissue from humans and monkeysGorazd Rosoklija
New York State Psychiatric Institute and Columbia University, Unit 62, 722 West 168th Street, 1051 Riverside Drive, New York, NY 10032, USA
J Neurosci Methods 131:1-7. 2003..When the appropriate method is chosen, Golgi impregnation is a useful technique for the neuropathologist...
A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressorsSanjay J Mathew
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
Biol Psychiatry 54:727-35. 2003..Long-term behavioral, immunologic, and neurochemical alterations have been found in primates exposed to adverse early rearing...
Managing the risks of repetitive transcranial stimulationBob Belmaker
Department of Psychiatry, Ben Gurion University, Beersheva, Israel
CNS Spectr 8:489. 2003
Transcranial magnetic stimulationMark S George
Department of Psychiatry, 502 North, Institute of Psychiatry, Medical University of South Carolina, 67 President Street, Charleston, SC, USA
Neurosurg Clin N Am 14:283-301. 2003..Whatever road the future takes, TMS is an important new tool that will likely be of interest to neurosurgeons over the next 20 years and perhaps even longer...
Focal brain stimulation with repetitive transcranial magnetic stimulation (rTMS): implications for the neural circuitry of depressionSarah H Lisanby
Psychol Med 33:7-13. 2003
Parietal cortex and representation of the mental SelfHans C Lou
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Proc Natl Acad Sci U S A 101:6827-32. 2004..This network is strikingly similar to the network of the resting conscious state, suggesting that self-monitoring is a core function in resting consciousness...
Research Grants
- MAGNETIC STIMULATION THERAPY: A NEW CONVULSIVE TREATMENTSarah Lisanby; Fiscal Year: 2003..This research will also explore the mechanisms of action of this clinically relevant putative treatment and lay the foundation for its development as a new treatment for psychiatric patients. ..
- MAGNETIC STIMULATION THERAPY: A NEW CONVULSIVE TREATMENTSarah Lisanby; Fiscal Year: 2007..This work continues the development of a promising new treatment and will inform the mechanisms of action of a well-established treatment, with broader implications for antidepressant action and epilepsy. ..
- Optimization of Transcranial Magnetic Stimulation for DepressionSarah Lisanby; Fiscal Year: 2009..This clinical site grant (CSG) proposal is one of four scientifically identical proposals resubmitted under a CSMD mechanism.] ..
