Research Topics
| Sarah H LisanbySummaryAffiliation: Columbia University Country: USA Publications
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Detail Information
Publications
Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomesLauren B Marangell
Department of Psychiatry, Baylor College of Medicine, One Baylor Plaza, BCM 350, Houston, TX 77030, USA
Biol Psychiatry 51:280-7. 2002..CONCLUSIONS: Longer-term vagus nerve stimulation treatment was associated with sustained symptomatic benefit and sustained or enhanced functional status in this naturalistic follow-up study...
Neocortical and hippocampal neuron and glial cell numbers in the rhesus monkeyJeppe Romme Christensen
Research Laboratory for Stereology and Neuroscience, Bispebjerg University Hospital, Copenhagen, Denmark
Anat Rec (Hoboken) 290:330-40. 2007..The results are phylogenetically consistent, apart from the neuron/glia ratio, which is remarkably higher than what is found in other species...
rTMS strategies for the study and treatment of schizophrenia: a reviewArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, Cabrini Hospital, Mt Sinai Medical Center, New York, NY 10032, USA
Int J Neuropsychopharmacol 11:563-76. 2008..Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy...
Focal electrically administered seizure therapy: a novel form of ECT illustrates the roles of current directionality, polarity, and electrode configuration in seizure inductionTimothy Spellman
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
Neuropsychopharmacology 34:2002-10. 2009..Future studies may examine whether these differences in seizure threshold and expression have clinical significance for patients receiving ECT...
Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatmentPhilip G Janicak
Department of Psychiatry, Rush University Medical Center, Chicago, IL 60612, USA
J Clin Psychiatry 69:222-32. 2008..We examined the acute efficacy of TMS in a randomized sham-controlled trial, under open-label conditions, and its durability of benefit...
Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodesZiad Nahas
Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29403, USA
J Clin Psychiatry 66:1097-104. 2005..We examined the effects of adjunctive VNS over 24 months in this cohort...
Differential effects of high-dose magnetic seizure therapy and electroconvulsive shock on cognitive functionTimothy Spellman
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
Biol Psychiatry 63:1163-70. 2008..5 x seizure threshold...
Electroconvulsive therapy for depressionSarah H Lisanby
Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Dr, Unit 21, New York, NY 10032, USA
N Engl J Med 357:1939-45. 2007
Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primatesTarique D Perera
Department of Biological Psychiatry, New York State Psychiatric Institute New York, New York 10032, USA
J Neurosci 27:4894-901. 2007..This study demonstrates that ECS is capable of inducing neurogenesis in the nonhuman primate hippocampus and supports the possibility that antidepressant interventions produce similar alterations in the human brain...
Randomized sham-controlled trial of repetitive transcranial magnetic stimulation in treatment-resistant obsessive-compulsive disorderAntonio Mantovani
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
Int J Neuropsychopharmacol 13:217-27. 2010..The results of the first randomized sham-controlled trial of SMA stimulation in the treatment of resistant OCD support further investigation into the potential therapeutic applications of rTMS in this disabling condition...
Differential neurophysiological effects of magnetic seizure therapy (MST) and electroconvulsive shock (ECS) in non-human primatesYael M Cycowicz
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, 1051 Riverside Drive, Unit 21, New York, NY 10032, USA
Clin EEG Neurosci 39:144-9. 2008..The clinical significance of these similarities and differences awaits clinical correlation...
Repetitive Transcranial Magnetic Stimulation (rTMS) in the treatment of panic disorder (PD) with comorbid major depressionAntonio Mantovani
Department of Psychiatry, Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 21, New York, NY 10032, USA
J Affect Disord 102:277-80. 2007..We tested whether low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) could normalize the overactivity of right frontal regions and thereby improve symptoms...
Effects of pulse width and electrode placement on the efficacy and cognitive effects of electroconvulsive therapyHarold A Sackeim
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Brain Stimul 1:71-83. 2008..Reducing the width of the electrical pulse and using the right unilateral electrode placement may decrease adverse cognitive effects, while preserving efficacy...
Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathyBrian A Fallon
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
Arch Gen Psychiatry 66:554-63. 2009..There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease...
Neuropathologic examination after 91 ECT treatments in a 92-year-old woman with late-onset depressionJason Scalia
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J ECT 23:96-8. 2007..Cognition in this patient was intact as indicated by a perfect score on a Mini-Mental Status Examination administered 6 days before death at the age of 92. This case adds to the considerable evidence for the safety of ECT...
Translational development strategy for magnetic seizure therapyStefan B Rowny
Brain Stimulation and Therapeutic Modulation Division, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 21, New York, NY 10032, USA
Exp Neurol 219:27-35. 2009....
Neurophysiological characterization of high-dose magnetic seizure therapy: comparisons with electroconvulsive shock and cognitive outcomesYael M Cycowicz
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, New York State Psychiatric Institute, Columbia University Medical Center, New York, NY 10032, USA
J ECT 25:157-64. 2009..It further suggests that some of the differences in ictal expression may relate to the improved cognitive outcomes seen with MST...
A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS)ANGEL V PETERCHEV
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York, NY 10032, USA
IEEE Trans Biomed Eng 55:257-66. 2008..The technological solutions used in the cTMS prototype can expand functionality, and reduce power consumption and coil heating in TMS, enhancing its research and therapeutic applications...
Coil design considerations for deep-brain transcranial magnetic stimulation (dTMS)Zhi De Deng
Department of Electrical Engineering and with the Division of Brain Stimulation and Therapeutic Modulation, Columbia University, New York, 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2008:5675-9. 2008..Preliminary simulation results suggest that the crown coil has the best overall performance for dTMS. Finally, synchronous firing of all TMS coil elements appears more effective at stimulating deep neurons than is sequential firing...
Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: clinical predictors of outcome in a multisite, randomized controlled clinical trialSarah H Lisanby
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
Neuropsychopharmacology 34:522-34. 2009..Shorter duration of current illness and lack of anxiety comorbidity may also confer an increased likelihood of good antidepressant response to TMS...
Toward individualized post-electroconvulsive therapy care: piloting the Symptom-Titrated, Algorithm-Based Longitudinal ECT (STABLE) interventionSarah H Lisanby
Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
J ECT 24:179-82. 2008..Here we back-test STABLE to optimize the algorithm for subsequent testing in a prospective trial...
Effect of anatomical variability on neural stimulation strength and focality in electroconvulsive therapy (ECT) and magnetic seizure therapy (MST)Zhi De Deng
Department of Electrical Engineering and with the Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York, NY 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2009:682-8. 2009..Individualization of pulse amplitude in both ECT and MST could compensate for anatomical variability, which could lead to more consistent clinical outcomes...
Lateral prefrontal cortex and self-control in intertemporal choiceBernd Figner
Center for Decision Sciences, Columbia University, New York, New York, USA
Nat Neurosci 13:538-9. 2010..rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice...
Randomized controlled trial of the cognitive side-effects of magnetic seizure therapy (MST) and electroconvulsive shock (ECS)Tammy D Moscrip
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY, USA
Int J Neuropsychopharmacol 9:1-11. 2006..Time to task completion following MST did not differ from sham. These findings suggest that MST results in a more benign acute cognitive side-effect profile than ECS in this model, consistent with initial observations with human MST...
Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysisTal Burt
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Int J Neuropsychopharmacol 5:73-103. 2002..We also review the application of TMS in the study of the pathophysiology of psychiatric disorders and summarize studies of the safety of TMS in human subjects...
Applications of TMS to therapy in psychiatrySarah H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, New York 10032, USA
J Clin Neurophysiol 19:344-60. 2002..Current challenges in the field include determining how to enhance the efficacy of TMS in these disorders and how to identify patients for whom TMS may be efficacious...
Update on magnetic seizure therapy: a novel form of convulsive therapySarah H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, Columbia University, New York, New York 10032, USA
J ECT 18:182-8. 2002....
Non-invasive brain stimulation in the detection of deception: scientific challenges and ethical consequencesBruce Luber
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University College of Physicians and Surgeons New York State Psychiatric Institute, New York, NY 10032, USA
Behav Sci Law 27:191-208. 2009..Ethical and legal consequences of the development of such a technology are discussed...
Safety and feasibility of magnetic seizure therapy (MST) in major depression: randomized within-subject comparison with electroconvulsive therapySarah H Lisanby
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Neuropsychopharmacology 28:1852-65. 2003..Magnetic seizure induction in patients with depression is feasible, and appears to have a superior acute side effect profile than ECT. Future research will be needed to establish whether MST has antidepressant efficacy...
Revisiting the backward masking deficit in schizophrenia: individual differences in performance and modeling with transcranial magnetic stimulationBruce Luber
Brain Stimulation and Therapeutic Modulation Division, New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 62:793-9. 2007..In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically...
New developments in electroconvulsive therapy and magnetic seizure therapySarah H Lisanby
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York City, USA
CNS Spectr 8:529-36. 2003..This article reviews the experience to date with MST, and places this work in the broader context of other means of optimizing convulsive therapy in the treatment of depression...
A primate model of anterograde and retrograde amnesia produced by convulsive treatmentTammy D Moscrip
Department of Biological Psychiatry, New York State Psychiatric Institute, New York, New York, USA
J ECT 20:26-36. 2004..This study developed and validated a cognitive battery to assess amnesia in nonhuman primates, providing new experimental paradigms for evaluating the cognitive effects of convulsive treatment...
Repetitive transcranial magnetic stimulation (rTMS) in the treatment of obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS)Antonio Mantovani
Department of Neuroscience, Section of Psychiatry, Section of Neurophysiology, Postgraduate School in Applied Neurological Sciences, Siena University, Siena, Italy
Int J Neuropsychopharmacol 9:95-100. 2006..Slow rTMS to SMA resulted in a significant clinical improvement and a normalization of the right hemisphere hyperexcitability, thereby restoring hemispheric symmetry in motor threshold...
High-frequency prefrontal repetitive transcranial magnetic stimulation for the negative symptoms of schizophrenia: a case seriesArielle D Stanford
Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, New York, NY, USA
J ECT 27:11-7. 2011..This pilot study assessed higher doses of rTMS and assessed particular demographic factors that may influence treatment response...
Neurophysiological characterization of magnetic seizure therapy (MST) in non-human primatesSarah H Lisanby
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
Suppl Clin Neurophysiol 56:81-99. 2003
Absence of histological lesions in primate models of ECT and magnetic seizure therapyAndrew J Dwork
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032, USA
Am J Psychiatry 161:576-8. 2004..The authors present preliminary findings from the first nonhuman primate neuropathological study of ECT to use perfusion fixation and adequate controls and the first to compare ECT with magnetic seizure therapy, to their knowledge...
Electroconvulsive therapy stimulus parameters: rethinking dosageANGEL V PETERCHEV
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY, USA
J ECT 26:159-74. 2010..All stimulus parameters should be noted in treatment records and published reports. To enable research on optimization of dosing paradigms, we suggest that ECT devices provide capabilities to adjust and display all stimulus parameters...
Cortical excitability in cocaine-dependent patients: a replication and extension of TMS findingsNashaat N Boutros
Department of Psychiatry, c o VA Connecticut Healthcare System, Yale University School of Medicine, 950 Campbell Avenue, 116A West Haven, CT 06516, USA
J Psychiatr Res 39:295-302. 2005..These data support our initial finding of decreased cortical excitability in abstinent cocaine-dependent subjects. We interpret this finding as a compensatory mechanism against the stimulating and epileptogenic effects of cocaine...
Electroconvulsive therapy and repetitive transcranial magnetic stimulation in children and adolescents: a review and report of two cases of epilepsia partialis continuaOscar G Morales
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, 1051 Riverside Drive, Box 126, New York, NY 10032 2695, USA
Child Adolesc Psychiatr Clin N Am 14:193-210, viii-ix. 2005....
Electroconvulsive therapy in the presence of deep brain stimulation implants: electric field effectsZhi De Deng
Department of Electrical Engineering, Columbia University New York State Psychiatric Institute, NY 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2010:2049-52. 2010....
Regional electric field induced by electroconvulsive therapy: a finite element simulation studyWon Hee Lee
Department of Biomedical Engineering, Columbia University, New York, NY 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2010:2045-8. 2010....
Repetitive transcranial magnetic stimulator with controllable pulse parameters (cTMS)ANGEL V PETERCHEV
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University NY State Psychiatric Institute, New York, NY 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2010:2922-6. 2010..The reduced power consumption and coil heating, and the flexible pulse parameter adjustment offered by cTMS could enhance existing TMS paradigms and could enable novel research and clinical applications with potentially enhanced potency...
Transcranial magnetic stimulation in the presence of deep brain stimulation implants: Induced electrode currentsZhi De Deng
Department of Electrical Engineering, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
Conf Proc IEEE Eng Med Biol Soc 2010:6821-4. 2010..These currents are an order of magnitude higher than the normal DBS pulses, and could result in tissue damage. When the IPG is turned off, electrode currents flow only if the TMS-induced voltage exceeds 5 V...
Electric field strength and focality in electroconvulsive therapy and magnetic seizure therapy: a finite element simulation studyZhi De Deng
Department of Psychiatry and Behavioral Sciences, Duke University, Box 3950 DUMC, Durham, NC 27710, USA
J Neural Eng 8:016007. 2011..Our results also indicate that the conventional ECT pulse amplitude (800-900 mA) is much higher than necessary for seizure induction. Reducing the ECT pulse amplitude should be explored as a potential means of diminishing side effects...
Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trialMark S George
Brain Stimulation Division, Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
Arch Gen Psychiatry 67:507-16. 2010..Daily left prefrontal repetitive transcranial magnetic stimulation (rTMS) has been studied as a potential treatment for depression, but previous work had mixed outcomes and did not adequately mask sham conditions...
A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressorsSanjay J Mathew
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
Biol Psychiatry 54:727-35. 2003..Long-term behavioral, immunologic, and neurochemical alterations have been found in primates exposed to adverse early rearing...
The efficacy of acute electroconvulsive therapy in atypical depressionMustafa M Husain
Department of Psychiatry, University of Texas UT Southwestern Medical Center at Dallas, TX 75390 8898, USA
J Clin Psychiatry 69:406-11. 2008..This study examined the characteristics and outcomes of patients with major depressive disorder (MDD), with or without atypical features, who were treated with acute bilateral electroconvulsive therapy (ECT)...
Differential heart rate response to magnetic seizure therapy (MST) relative to electroconvulsive therapy: a nonhuman primate modelStefan B Rowny
Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 21, Room 5100, New York, NY 10032, USA
Neuroimage 47:1086-91. 2009..The clinical relevance of the topographical seizure spread of MST and its associated effects on the autonomic nervous system remain to be determined in human clinical trials...
Optimization of Golgi methods for impregnation of brain tissue from humans and monkeysGorazd Rosoklija
New York State Psychiatric Institute and Columbia University, Unit 62, 722 West 168th Street, 1051 Riverside Drive, New York, NY 10032, USA
J Neurosci Methods 131:1-7. 2003..When the appropriate method is chosen, Golgi impregnation is a useful technique for the neuropathologist...
Transcranial magnetic stimulationMark S George
Department of Psychiatry, 502 North, Institute of Psychiatry, Medical University of South Carolina, 67 President Street, Charleston, SC, USA
Neurosurg Clin N Am 14:283-301. 2003..Whatever road the future takes, TMS is an important new tool that will likely be of interest to neurosurgeons over the next 20 years and perhaps even longer...
Parietal cortex and representation of the mental SelfHans C Lou
Magnetic Brain Stimulation Laboratory, Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
Proc Natl Acad Sci U S A 101:6827-32. 2004..This network is strikingly similar to the network of the resting conscious state, suggesting that self-monitoring is a core function in resting consciousness...
Magnetic seizure therapy improves mood in refractory major depressionMarkus Kosel
Department of Psychiatry, University Hospital Bern, Switzerland
Neuropsychopharmacology 28:2045-8. 2003..Our preliminary data support the prospect of antidepressant efficacy of MST and point to a benign cognitive side-effect profile in a patient suffering from severe treatment-resistant major depression...
Evidence for impaired cortical inhibition in patients with unipolar major depressionMalek Bajbouj
Department of Psychiatry, Charite University Medicine Berlin, Berlin, Germany
Biol Psychiatry 59:395-400. 2006..Transcranial magnetic stimulation is a useful tool for investigating central cortical inhibitory mechanisms associated with GABAergic neurotransmission in psychiatric and neurological disorders...
Anesthetic considerations for magnetic seizure therapy: a novel therapy for severe depressionPaul F White
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9068, USA
Anesth Analg 103:76-80, table of contents. 2006..Further studies are required to evaluate the antidepressant efficacy of MST versus ECT when they are administered at comparable levels of cerebral stimulation...
Motor cortex excitability after vagus nerve stimulation in major depressionMalek Bajbouj
Department of Psychiatry, Charite Universitatsmedizin Berlin, Germany
J Clin Psychopharmacol 27:156-9. 2007..These results suggest that VNS is capable of changing motor cortical excitability in patients with depression...
Repetitive Transcranial Magnetic Stimulation of the Supplementary Motor Area in the treatment of Tourette Syndrome: report of two casesAntonio Mantovani
Clin Neurophysiol 118:2314-5. 2007
Transcranial magnetic stimulation in the acute treatment of major depressive disorder: clinical response in an open-label extension trialDavid H Avery
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
J Clin Psychiatry 69:441-51. 2008....
Quick recovery of orientation after magnetic seizure therapy for major depressive disorderGeorge Kirov
Cardiff University, Henry Wellcome Building, Heath Park, Cardiff, UK
Br J Psychiatry 193:152-5. 2008..Its use may be justified if it produces the antidepressant effects of electroconvulsive therapy (ECT), coupled with limited cognitive side-effects...
Managing the risks of repetitive transcranial stimulationBob Belmaker
Department of Psychiatry, Ben Gurion University, Beersheva, Israel
CNS Spectr 8:489. 2003
Focal brain stimulation with repetitive transcranial magnetic stimulation (rTMS): implications for the neural circuitry of depressionSarah H Lisanby
Psychol Med 33:7-13. 2003
