Research Topics
| Frances LevinSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Treatment of cannabis use disorders: a review of the literatureBenjamin R Nordstrom
Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute and College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Am J Addict 16:331-42. 2007..We also review pertinent dual-diagnosis pharmacotherapy trials and discuss potential future directions in treatment research for the pharmacotherapy of cannabis dependence...
A comparison of psychosocial and cognitive functioning between depressed and non-depressed patients with cannabis dependenceAlex M Secora
Division of Substance Abuse, New York State Psychiatric Institute, New York, NY 10032, USA
J Addict Dis 29:325-37. 2010..Based on the authors' results, they concluded that the additive effects of cannabis dependency and depression may only be limited to psychosocial domains and may not extend to cognitive functioning...- Use of standardized patients to evaluate the physicians in residence program: a substance abuse training approachF R Levin
Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, USA
J Addict Dis 18:39-50. 1999..Overall, self-report ratings showed a greater percent improvement than the counselor ratings. The PIR program may be an efficacious approach to teach substance abuse clinical skills to housestaff... - Severity of dependence and motivation for treatment: comparison of marijuana- and cocaine-dependent treatment seekersFrances R Levin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
J Addict Dis 25:33-41. 2006.... - Diagnosing attention-deficit/hyperactivity disorder in patients with substance use disordersFrances Rudnick Levin
Division on Substance Abuse, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
J Clin Psychiatry 68:9-14. 2007.... - Use of dronabinol for cannabis dependence: two case reports and reviewFrances R Levin
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
Am J Addict 17:161-4. 2008..The potential benefit, as well as questions that arise from the use of this medication in cannabis-abusing populations, is presented. Also, future areas of research that might be explored are discussed... - Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trialFrances R Levin
New York State Psychiatric Institute, Division of Substance Abuse, New York, NY 10032, USA
Drug Alcohol Depend 116:142-50. 2011..Future trials might test higher doses, combinations of dronabinol with other medications with complementary mechanisms, or with more potent behavioral interventions... - Bipolar disorder and substance abuseFrances R Levin
Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
Biol Psychiatry 56:738-48. 2004..Finally, we present suggestions for medications that might be tested for their efficacy in treating both disorders in specific subgroups of patients with bipolar and substance use disorders... - Impact of attention-deficit hyperactivity disorder and other psychopathology on treatment retention among cocaine abusers in a therapeutic communityFrances Rudnick Levin
Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive Unit 66, New York City, NY 10032, USA
Addict Behav 29:1875-82. 2004..Future investigations may be useful to determine whether pharmacologic or nonpharmacologic interventions might improve treatment outcome... - Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinolFrances R Levin
New York State Psychiatric Institute, Division on Substance Abuse, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
Drug Alcohol Depend 106:65-8. 2010..We propose that the lack of THCV detection may be due to the variability of available cannabis strains smoked by marijuana users in community settings... - Pharmacotherapy for marijuana dependence: a double-blind, placebo-controlled pilot study of divalproex sodiumFrances Rudnick Levin
Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Am J Addict 13:21-32. 2004..The design of a preliminary clinical trial should include a psychosocial/behavioral intervention emphasizing motivation and medication compliance and a placebo control group... - Pergolide mesylate for cocaine abuse: a controlled preliminary trialF R Levin
Department of Psychiatry, Columbia University New York State Psychiatric Institute, NY 10032, USA
Am J Addict 8:120-7. 1999..Comparing an agent to both an active control and placebo group may better predict whether a promising new agent will have clinical utility compared to the standard open trial... - Temperament characteristics, as assessed by the tridimensional personality questionnaire, moderate the response to sertraline in depressed opiate-dependent methadone patientsWilfrid Noel Raby
Substance Treatment and Research Service S T A R S, Division on Substance Abuse, Department of Psychiatry, New York State Psychiatric Institute and Columbia University, 1051 Riverside Drive, NYC, NY 10032, USA
Drug Alcohol Depend 81:283-92. 2006..These results suggest that temperament dimensions may be important for identifying substance dependent patients more likely to benefit from pharmacological interventions for comorbid depressive disorders... - A preliminary trial: double-blind comparison of nefazodone, bupropion-SR, and placebo in the treatment of cannabis dependenceKenneth M Carpenter
Division on Substance Abuse, New York State Psychiatric Institute, New York, USA
Am J Addict 18:53-64. 2009..The results indicate nefazodone and bupropion-sustained release may have limited efficacy in treating cannabis dependence... - One-year follow-up study of suicide attempters treated for drug dependenceVito Agosti
New York State Psychiatric Institute, Depression Evaluation Service, New York, New York 10032, USA
Am J Addict 15:293-6. 2006.... - Training physicians to treat substance use disordersSoteri Polydorou
Columbia University Medical Center New York State Psychiatric Institute, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Curr Psychiatry Rep 10:399-404. 2008..Further integration of online training into current programs may expand and enhance training opportunities... 
Uses of coercion in addiction treatment: clinical aspectsMaria A Sullivan
Columbia College of Physicians and Surgeons New York State Psychiatric Institute, New York, NY 10032, USA
Am J Addict 17:36-47. 2008..The philosophical, historical, and societal aspects of coerced treatment are considered...- Quetiapine treatment of zolpidem dependenceJohn J Mariani
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Am J Addict 16:426. 2007 - Early abstinence in cocaine dependence: influence of comorbid major depressionEric Rubin
Division on Substance Abuse, Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, New York 10032, USA
Am J Addict 16:283-90. 2007..By Day 3, BDI scores improved for both CD and CD + MDD groups. The mood response to cocaine cessation among CD + MDD individuals resembled that of CD participants, contrary to some expectations... - Comparison of olanzapine to risperidone in substance-abusing individuals with schizophreniaEvaristo Akerele
Department of Psychiatry, Harlem Hospital, College of Physicians and Surgeons of Columbia University, New York, New York 10037, USA
Am J Addict 16:260-8. 2007..The data suggest some potential for the utility of olanzapine for the treatment of cocaine dependence in individuals with schizophrenia... - Effects of major depressive disorder and attention-deficit/hyperactivity disorder on the outcome of treatment for cocaine dependenceFrances R Levin
New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Subst Abuse Treat 34:80-9. 2008.... - Antisocial behavioral syndromes in cocaine and cannabis dependenceJohn J Mariani
New York State Psychiatric Institute, Division on Substance Abuse, New York, NY 10032, USA
Am J Drug Alcohol Abuse 34:405-14. 2008..Antisocial behavioral syndromes are commonly diagnosed in patients with SUD and future research should evaluate prognostic implications of AABS compared to ASPD in a variety of clinical treatment settings... - Impact of a brief training on medical resident screening for alcohol misuse and illicit drug useErik W Gunderson
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
Am J Addict 17:149-54. 2008..05), as did inquiry about current illicit drug use (p < .05). Continued efforts are needed to enhance educational initiatives for primary care physicians... - Effects of research setting on observed depressive symptoms in marijuana usersJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
J Subst Abuse Treat 37:431-4. 2009..e., treatment-seekers are more likely to be experiencing some degree of clinical distress), it is notable that treatment-seeking, and not marijuana use per se, is associated with significantly higher rates of depression... - The effects of progesterone pretreatment on the response to oral d-amphetamine in WomenStephanie C Reed
Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Horm Behav 58:533-43. 2010..Additional studies are needed to explore the modulatory role of progesterone on the effects of AMPH to determine whether progesterone has any clinical utility for AMPH abuse... - Levetiracetam for the treatment of co-occurring alcohol dependence and anxiety: case series and reviewJohn J Mariani
Division on Substance Abuse, New York State Psychiatric Institute, New York, New York 10032, USA
Am J Drug Alcohol Abuse 34:683-91. 2008..There is pre-clinical and clinical evidence that levetiracetam, a newer generation anticonvulsant medication, may be efficacious in the treatment of co-occurring alcohol use and anxiety disorders... - Does remission from alcohol and drug use disorders increase the likelihood of smoking cessation among nicotine dependent young adults?Vito Agosti
New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
Soc Psychiatry Psychiatr Epidemiol 44:120-4. 2009..This article tests the hypothesis that remission from substance use disorders is associated with smoking cessation in nicotine dependent young adults... - A placebo-controlled trial of memantine for cocaine dependence with high-value voucher incentives during a pre-randomization lead-in periodAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
Drug Alcohol Depend 111:97-104. 2010..Targeting the latter subgroup may advance medication development efforts... - Pediatric obesity: parallels with addiction and treatment recommendationsMichelle C Acosta
Department of Psychiatry, Columbia University, New York, NY, USA
Harv Rev Psychiatry 16:80-96. 2008..The parallels between addiction and obesity aid in developing novel interventions for pediatric obesity. Motivational enhancement and cognitive-behavioral strategies used in addiction treatment may prove to be beneficial... - Changes in mood, cognitive performance and appetite in the late luteal and follicular phases of the menstrual cycle in women with and without PMDD (premenstrual dysphoric disorder)Stephanie Collins Reed
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
Horm Behav 54:185-93. 2008..An altered serotonergic system in women with PMDD may be the underlying mechanism for the observed symptoms; correspondingly, treatment with specific serotonin reuptake inhibitors (SSRIs) remains the preferred treatment at this time... - The emerging role of meditation in addressing psychiatric illness, with a focus on substance use disordersElias Dakwar
Division of Substance Abuse, New York State Psychiatric Institute Columbia Presbyterian Medical Center, New York, NY 10032, USA
Harv Rev Psychiatry 17:254-67. 2009..A brief discussion then integrates the research that has been completed thus far, elucidates the specific ways that meditation may be helpful for substance use disorders, and suggests new avenues for research... - Treatment strategies for co-occurring ADHD and substance use disordersJohn J Mariani
New York State Psychiatric Institute, New York, New York, USA
Am J Addict 16:45-54; quiz 55-6. 2007..Recommendations for treatment planning and clinical management for patients with co-occurring ADHD and SUD are discussed... - A pilot double-blind treatment trial of memantine for alcohol dependenceSuzette M Evans
New York State Psychiatric Institute, New York, New York 10032, USA
Alcohol Clin Exp Res 31:775-82. 2007..This 16-week double-blind outpatient pilot clinical trial determined if memantine was more effective than placebo at reducing alcohol use in actively drinking alcohol-dependent patients... - Predictors of cannabis dependence recovery among epidemiological survey respondents in the United StatesVito Agosti
New York State Psychiatric Institute, New York, New York 10032, USA
Am J Drug Alcohol Abuse 33:81-8. 2007..Recovery was defined as the absence of Cannabis Dependence and Cannabis Abuse during the past year. Logistic Regression analysis revealed that older age, marriage, and non-daily cannabis use were positively associated with recovery... - Treatment of methadone-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placeboFrances R Levin
New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Drug Alcohol Depend 81:137-48. 2006..Taken together, sustained-release methylphenidate or sustained-release bupropion did not provide a clear advantage over placebo in reducing ADHD symptoms or additional cocaine use in methadone-maintained patients... - Screening and intervention for alcohol and illicit drug abuse:a survey of internal medicine housestaffErik W Gunderson
Department of Psychiatry, Division on Substance Abuse, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Addict Dis 24:1-18. 2005..These findings suggest areas to be addressed in residency curricula on substance abuse... - Pharmacotherapy for alcohol-related disorders: what clinicians should knowJohn J Mariani
Department of Psychiatry, Division on Substance Abuse, Columbia University, College of Physicians and Surgeons, USA
Harv Rev Psychiatry 12:351-66. 2004..The routine exclusion of alcohol-dependent patients from pharmacotherapy trials of psychiatric disorders presents a barrier to gathering more data. Recommendations for future research are discussed... - Utility of lead-in period in cocaine dependence pharmacotherapy trialsAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, NY, USA
Drug Alcohol Depend 77:7-11. 2005..Findings of this study suggest that route and level of cocaine use during lead-in be used as a covariate in models testing treatment effect... - Treatment of depression in patients with opiate dependenceEdward V Nunes
New York State Psychiatric Institute, and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Biol Psychiatry 56:793-802. 2004..Research is needed on such integrated models of care and treatment algorithms to determine their efficacy and cost effectiveness... - Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to actionDennis S Charney
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104-6178, USA
Biol Psychiatry 56:703-13. 2004 - Treatment of depression in patients with alcohol or other drug dependence: a meta-analysisEdward V Nunes
Depression Evaluation Service, New York State Psychiatric Institute and Department of Psychiatry, Columbia University, New York 10032, USA
JAMA 291:1887-96. 2004..Depression and substance abuse are common and costly disorders that frequently co-occur, but controversy about effective treatment for patients with both disorders persists... - Predictors of treatment contact among individuals with cannabis dependenceVito Agosti
New York State Psychiatric Institute, 1051 Riverside Drive Box 51, New York, NY 10032, USA
Am J Drug Alcohol Abuse 30:121-7. 2004.... - Response to alcohol in females with a paternal history of alcoholismSuzette M Evans
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Psychopharmacology (Berl) 169:10-20. 2003..g. lower ratings of intoxication) than males without a family history of alcoholism (FHN). The purpose of this pilot study was to determine if FHP females also showed a reduced sensitivity to alcohol compared to FHN females... - A randomized placebo-controlled trial of gabapentin for cocaine dependenceAdam Bisaga
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
Drug Alcohol Depend 81:267-74. 2006..Gabapentin is an anticonvulsant medication that increases human brain GABA levels. We evaluated the safety and efficacy of gabapentin combined with relapse-prevention therapy in the treatment of cocaine-dependent individuals... - Response to cocaine, alone and in combination with methylphenidate, in cocaine abusers with ADHDStephanie L Collins
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Drug Alcohol Depend 82:158-67. 2006..Thus, oral MPH-SR is safe in combination with repeated cocaine doses and decreases some of the positive and reinforcing effects of cocaine in cocaine abusers with ADHD... - Attention-deficit/hyperactivity disorder and early-onset substance use disordersJeffrey J Wilson
Division on Substance Abuse, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
J Child Adolesc Psychopharmacol 15:751-63. 2005..More research is needed to definitively assess the effectiveness and safety of medications in this population of youths with ADHD and SUD... - Evaluation of a combined online and in person training in the use of buprenorphineErik W Gunderson
Columbia University College of Physicians and Surgeon and New York State Psychiatric Institute, New York, NY, USA
Subst Abus 27:39-45. 2006..Overall, physicians preferred in person instruction and may benefit from additional experiential training and support after curriculum participation... - Concurrent cannabis use during treatment for comorbid ADHD and cocaine dependence: effects on outcomeEfrat Aharonovich
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Am J Drug Alcohol Abuse 32:629-35. 2006..02). This study is the first to examine concurrent cannabis use in cocaine dependent patients diagnosed with ADHD... - Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependenceDaniel J Brooks
New York State Psychiatry Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
J Addict Dis 25:15-25. 2006..Diagnostic services capable of identifying cognitive deficits among MMP with ADHD and/or CD are needed to maximize the likelihood of treatment success and to serve as an indicator for the efficacy of therapeutic approaches... - Treating depression in substance abusersEdward V Nunes
New York State Psychiatric Institute, 1051 Riverside Drive Unit 51, New York, NY 10032, USA
Curr Psychiatry Rep 8:363-70. 2006.... - Bupropion treatment for cocaine abuse and adult attention-deficit/hyperactivity disorderFrances R Levin
Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York 10032, USA
J Addict Dis 21:1-16. 2002..However, a future study directly comparing BPR to MPH in a double-blind placebo-controlled trial is needed... - Adult ADHD and substance abuse: diagnostic and treatment issuesAparna S Kalbag
New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York, USA
Subst Use Misuse 40:1955-81, 2043-8. 2005..The present review discusses diagnostic assessment issues, prevalence, comorbidity, pharmacotherapy, and psychological interventions in substance-abusing adults with ADHD... - The effects of alcohol and drug dependence on the course of depressionVito Agosti
Substance Use Research Center, New York State Psychiatric Institute, New York, New York 10032, USA
Am J Addict 15:71-5. 2006..This study analyzed data from the National Comorbidity Survey (NCS). Among respondents with lifetime SUD and unipolar depression, current SUD increased the risk (OR = 2.9) of past year depression and anxiety disorders (OR = 2.2)... - Verbal abilities as predictors of retention among adolescents in a therapeutic communityJeffrey J Wilson
Department of Psychiatry, Division on Substance Abuse, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 66, New York, NY 10032, USA
Child Psychiatry Hum Dev 36:393-401. 2006..Remediation of verbal communication skills may be an overlooked aspect of the therapeutic process in treating adolescent substance abusers... - Treatment of cocaine dependent treatment seekers with adult ADHD: double-blind comparison of methylphenidate and placeboFrances R Levin
New York State Psychiatric Institute, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Drug Alcohol Depend 87:20-9. 2007.... - Quantification and comparison of marijuana smoking practices: blunts, joints, and pipesJohn J Mariani
New York State Psychiatric Institute, Division on Substance Abuse, 1051 Riverside Drive, Unit 66, New York, NY 10032, USA
Drug Alcohol Depend 113:249-51. 2011..Individual variability in use practices limits the utility of this method to estimating within-subject comparisons, rather than between subject comparisons... - Response to alcohol in women: role of the menstrual cycle and a family history of alcoholismSuzette M Evans
New York State Psychiatric Institute and Departmentof Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Drug Alcohol Depend 114:18-30. 2011.... - Rates of psychiatric comorbidity among U.S. residents with lifetime cannabis dependenceVito Agosti
New York State Psychiatric Institute, Substance Abuse Treatment Center, 1051 Riverside Drive, New York, NY 10032, USA
Am J Drug Alcohol Abuse 28:643-52. 2002..The failure to identify comorbidity may lead to inadequate treatment, and a poorer prognosis... - Diagnosing ADHD in adults with substance use disorder: DSM-IV criteria and differential diagnosisFrances R Levin
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, USA
J Clin Psychiatry 68:e18. 2007..If proper attention is paid to age-appropriate symptoms of ADHD, and careful longitudinal data are obtained from patients presenting with ADHD or SUD, proper treatment can be given to patients with these comorbid disorders... - Effects of HIV triple therapy on methadone levelsEvaristo O Akerele
Division of Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
Am J Addict 11:308-14. 2002..These preliminary findings suggest that triple therapy may increase the rate of methadone metabolism, though further studies are warranted... - Comorbid psychiatric and substance abuse disorders: recent treatment researchPaula Riggs
Department of Psychiatry, University of Colorado Health Science Cneter, Denver, CO 80224, USA
Subst Abus 29:51-63. 2008..Treatment of ADHD and substance use disorders in adults; 3. Effects of substance abuse on the onset, severity, and treatment of schizophrenia. Recommendations for further research will be presented...
Research Grants
- RESEARCH FELLOWSHIP IN SUBSTANCE ABUSE DISORDERSFrances Levin; Fiscal Year: 2007..Currently, there are 16 faculty members within the Division of which 9 are capable of serving as mentors. This sustained growth demonstrates how vibrant the Division on Substance Abuse is for young investigators. ..
- TREATMENT OF SUBSTANCE ABUSE AND PSYCHIATRIC COMORBIDITYFrances Levin; Fiscal Year: 2007..Finally, the applicant will continue to contribute to a variety of educational activities at the National and local level, provide ongoing mentorship to young clinical investigators, and offer service to the Substance Abuse field. ..
- Marijuana Dependence & Depression: Venlafaxine TreatmentFrances Levin; Fiscal Year: 2006..3. To examine the relationship between medication treatment, mood improvement, cognitive functioning and improvement in marijuana abuse using mediational analyses. ..
- Combined Pharmacotherapies for Cocaine DependenceFrances Levin; Fiscal Year: 2007..3. To explore a set of related secondary outcomes (treatment retention, global functioning, and HIV risk behavior) as well as moderators and mediators potentially reflective of mechanism of action. ..
- Extended Release Mixed Amphetamine Salts for Adult ADHD and Cocaine DependenceFrances Levin; Fiscal Year: 2007..Here a nearly unique opportunity exists to treat two conditions, ADHD and cocaine dependence, with a single medication, hopefully leading to improved treated outcome in this difficult-to-treat population. ..
- Extended Release Mixed Amphetamine Salts for Adult ADHD and Cocaine DependenceFrances Levin; Fiscal Year: 2009..Here a nearly unique opportunity exists to treat two conditions, ADHD and cocaine dependence, with a single medication, hopefully leading to improved treated outcome in this difficult-to-treat population. ..
- TREATMENT OF ADULT ADHD IN METHADONE PATIENTSFrances Levin; Fiscal Year: 2002..Overall, this proposal will provide a better understanding of the relationship between ADHD and substance abuse, better diagnostic evaluation, and improved pharmacologic treatment approaches for this sub-population. ..
- METHYLPHENIDATE TREATMENT FOR COCAINE ABUSE AND ADHDFrances Levin; Fiscal Year: 2002..2) To determine if sustained-release MPH is more effective than placebo in reducing ADHD symptoms in cocaine abusers with adult ADHD. 3) To determine if improvement in ADHD symptoms precedes a reduction in cocaine use. ..
- Marijuana Abusing ADHD Teens: Atomoxetine TreatmentFrances Levin; Fiscal Year: 2004..4. To examine the relationship between medication treatment, reduction in ADHD symptoms, and improvement in retention and/or progress in treatment using mediational analyses. ..
- Extended Release Mixed Amphetamine Salts for Adult ADHD and Cocaine DependenceFrances Rudnick Levin; Fiscal Year: 2010..Here a nearly unique opportunity exists to treat two conditions, ADHD and cocaine dependence, with a single medication, hopefully leading to improved treated outcome in this difficult-to-treat population. ..