BLANDINE LAFERRERE

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Magnitude and variability of the glucagon-like peptide-1 response in patients with type 2 diabetes up to 2 years following gastric bypass surgery
    Bart J Van der Schueren
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, New York, NewYork, USA
    Diabetes Care 35:42-6. 2012
  2. pmc Gut feelings about diabetes
    BLANDINE LAFERRERE
    Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Endocrinol Nutr 59:254-60. 2012
  3. ncbi request reprint Total body calcium in obese women. Validation of dual-energy X-ray absorptiometry against in vivo neutron activation analysis
    B Laferrere
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, New York 10025, USA
    Ann N Y Acad Sci 904:507-13. 2000
  4. pmc Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes
    BLANDINE LAFERRERE
    St Lukes Roosevelt Hospital, Obesity Research Center, 1111 Amsterdam Avenue, New York, NY 10025, USA
    J Clin Endocrinol Metab 93:2479-85. 2008
  5. pmc Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Obesity (Silver Spring) 14:1056-63. 2006
  6. pmc Rise of oxyntomodulin in response to oral glucose after gastric bypass surgery in patients with type 2 diabetes
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    J Clin Endocrinol Metab 95:4072-6. 2010
  7. pmc Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss
    BLANDINE LAFERRERE
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Sci Transl Med 3:80re2. 2011
  8. pmc Do we really know why diabetes remits after gastric bypass surgery?
    BLANDINE LAFERRERE
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Endocrine 40:162-7. 2011
  9. pmc Diabetes remission after bariatric surgery: is it just the incretins?
    B Laferrere
    New York Obesity Nutrition Research Center, Division of Endocrinology and Diabetes, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes (Lond) 35:S22-5. 2011
  10. ncbi request reprint Race, menopause, health-related quality of life, and psychological well-being in obese women
    BLANDINE LAFERRERE
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, New York 10025, USA
    Obes Res 10:1270-5. 2002

Research Grants

  1. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2006
  2. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE B LAFERRERE; Fiscal Year: 2010
  3. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2005
  4. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE B LAFERRERE; Fiscal Year: 2010
  5. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2009

Collaborators

Detail Information

Publications36

  1. pmc Magnitude and variability of the glucagon-like peptide-1 response in patients with type 2 diabetes up to 2 years following gastric bypass surgery
    Bart J Van der Schueren
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, New York, NewYork, USA
    Diabetes Care 35:42-6. 2012
    ..To characterize the magnitude and variance of the change of glucose and glucagon-like peptide-1 (GLP-1) concentrations, and to identify determinants of glucose control up to 2 years after gastric bypass (GBP)...
  2. pmc Gut feelings about diabetes
    BLANDINE LAFERRERE
    Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Endocrinol Nutr 59:254-60. 2012
    ..While most patients after bariatric surgery experienced sustained weight loss and improved metabolism, small scale studies have shown weight regain and diabetes relapse, the mechanisms of which remain unknown...
  3. ncbi request reprint Total body calcium in obese women. Validation of dual-energy X-ray absorptiometry against in vivo neutron activation analysis
    B Laferrere
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, New York 10025, USA
    Ann N Y Acad Sci 904:507-13. 2000
    ..The higher the BMI, the bigger the difference between CaIVNA and CaDXA. In our population with a mean BMI of 35.3, CaIVNA = 69% CaDXA...
  4. pmc Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes
    BLANDINE LAFERRERE
    St Lukes Roosevelt Hospital, Obesity Research Center, 1111 Amsterdam Avenue, New York, NY 10025, USA
    J Clin Endocrinol Metab 93:2479-85. 2008
    ..Gastric bypass surgery (GBP) results in rapid weight loss, improvement of type 2 diabetes (T2DM), and increase in incretins levels. Diet-induced weight loss also improves T2DM and may increase incretin levels...
  5. pmc Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Obesity (Silver Spring) 14:1056-63. 2006
    ..The aim of this study was to investigate whether this effect occurs in obese subjects and whether it is dose-dependent...
  6. pmc Rise of oxyntomodulin in response to oral glucose after gastric bypass surgery in patients with type 2 diabetes
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    J Clin Endocrinol Metab 95:4072-6. 2010
    ..The mechanisms by which Roux-en-Y gastric bypass surgery (GBP) results in sustained weight loss and remission of type 2 diabetes are not fully understood...
  7. pmc Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss
    BLANDINE LAFERRERE
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Sci Transl Med 3:80re2. 2011
    ..These data suggest that the enhanced decrease in circulating AAs after GBP occurs by mechanisms other than weight loss and may contribute to the better improvement in glucose homeostasis observed with the surgical intervention...
  8. pmc Do we really know why diabetes remits after gastric bypass surgery?
    BLANDINE LAFERRERE
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Endocrine 40:162-7. 2011
    ..Equally important would be to identify biological predictors of success or failure and to understand the mechanisms of weight regain and/or diabetes relapse...
  9. pmc Diabetes remission after bariatric surgery: is it just the incretins?
    B Laferrere
    New York Obesity Nutrition Research Center, Division of Endocrinology and Diabetes, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes (Lond) 35:S22-5. 2011
    ..Changes in rate of eating, gastric emptying, intestinal transit time, nutrient absorption and sensing, as well as bile acid metabolism, may all be implicated...
  10. ncbi request reprint Race, menopause, health-related quality of life, and psychological well-being in obese women
    BLANDINE LAFERRERE
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, New York 10025, USA
    Obes Res 10:1270-5. 2002
    ..To investigate the health-related quality of life (HR-QOL) in African-American (AA) and white (W) obese women...
  11. pmc A pulse of insulin and dexamethasone stimulates serum leptin in fasting human subjects
    B Laferrere
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University, 1111 Amsterdam Avenue, New York, New York 10025, USA
    Eur J Endocrinol 146:839-45. 2002
    ..Whether the presence of transient hyperglycemia and the dose of insulin were important was tested as a secondary aim...
  12. pmc Effect of one morning meal and a bolus of dexamethasone on 24-hour variation of serum leptin levels in humans
    B Laferrere
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University, New York, New York 10025, USA
    Obes Res 8:481-6. 2000
    ..The present experiment was undertaken to determine the duration of the effect of dexamethasone on 24-hour serum leptin under fasted and fed conditions in humans...
  13. pmc Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Ave, New York, NY 10025, USA
    Diabetes Care 30:1709-16. 2007
    ..We hypothesized that in obese patients with type 2 diabetes the impaired levels and effect of incretins changed as a consequence of RY-GBP...
  14. pmc Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery
    Mousumi Bose
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Diabetes 2:47-55. 2010
    ..The aim of the present study was to determine the mechanisms underlying Type 2 diabetes remission after gastric bypass (GBP) surgery by characterizing the short- and long-term changes in hormonal determinants of blood glucose...
  15. pmc Effects of gastrogastric fistula repair on weight loss and gut hormone levels
    Ciaran S O'Brien
    New York Obesity Nutrition Research Center, Department of Medicine, St Luke s Roosevelt Hospital Center, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Obes Surg 23:1294-301. 2013
    ..To further understand the mechanisms by which GGF may lead to weight regain, we investigated gut hormone levels in GBP patients with a GGF, before and after repair...
  16. pmc Do Incretins play a role in the remission of type 2 diabetes after gastric bypass surgery: What are the evidence?
    Mousumi Bose
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Obes Surg 19:217-29. 2009
    ..Our goals are to provide a thorough update on this field of research so that recommendations for future research and criteria for bariatric surgery can be evaluated...
  17. ncbi request reprint Prevalence of co-morbidities in obese patients before bariatric surgery: effect of race
    Luigi Residori
    Obesity Research Center and Department of Medicine, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    Obes Surg 13:333-40. 2003
    ..We evaluated the prevalence of co-morbidities, in particular diabetes, in a diverse population of morbidly obese patients who underwent gastric bypass surgery at our institution in New York City...
  18. pmc Effect of weight loss by diet or gastric bypass surgery on peptide YY3-36 levels
    Blanca Olivan
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Ann Surg 249:948-53. 2009
    ..To examine the effect of an equivalent weight loss, by gastric bypass surgery (GBP) or by diet, on peptide YY3-36 (PYY3-36), ghrelin, and leptin levels and to determine the effect of diabetes status on PYY3-36 levels...
  19. ncbi request reprint Depression score predicts weight loss following Roux-en-Y gastric bypass
    Yelena Averbukh
    Department of Medicine, St Luke s Roosevelt Hospital, New York, USA
    Obes Surg 13:833-6. 2003
    ..The association between pre-surgical severity of depression and success at weight loss following Roux-en-Y gastric bypass (RYGBP) has not yet been fully elucidated...
  20. pmc Superior appetite hormone profile after equivalent weight loss by gastric bypass compared to gastric banding
    Mousumi Bose
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, New York, USA
    Obesity (Silver Spring) 18:1085-91. 2010
    ..Mechanisms other than weight loss may explain changes of leptin and amylin after GBP...
  21. pmc Neural responsivity to food cues in fasted and fed states pre and post gastric bypass surgery
    Christopher N Ochner
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital, NY 10025, USA
    Neurosci Res 74:138-43. 2012
    ..Results were opposite to that predicted and appear inconsistent with the initial hypothesis that postoperative increases in postprandial gut peptides are the primary driver of postoperative changes in neural responsivity...
  22. ncbi request reprint Incretins, diabetes, and bariatric surgery: a review
    Rachel Fetner
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Surg Obes Relat Dis 1:589-97; discussion 597-8. 2005
  23. ncbi request reprint Korean and Caucasian overweight premenopausal women have different relationship of body mass index to percent body fat with age
    Sochung Chung
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital and College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    J Appl Physiol 99:103-7. 2005
    ..Investigators who use BMI as an index of fatness should be aware of the well documented differences in the relationship of BMI and fatness across race/ethnic groups...
  24. ncbi request reprint Does ghrelin really matter after bariatric surgery?
    Hongchan Lee
    Division of Bariatric Surgery, Department of Surgery, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Surg Obes Relat Dis 2:538-48. 2006
  25. pmc Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, New York 10025, USA
    J Clin Endocrinol Metab 90:611-4. 2005
    ..412 +/- 161 microg/L/240 min, p = 0.003). These data are the first to demonstrate that GHRP-2, like ghrelin, increases food intake, suggesting that GHRP-2 is a valuable tool for investigating ghrelin effects on eating behavior in humans...
  26. ncbi request reprint Comparisons of waist circumferences measured at 4 sites
    Jack Wang
    Body Composition Unit and New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York 10025, USA
    Am J Clin Nutr 77:379-84. 2003
    ....
  27. pmc Accelerated gastric emptying but no carbohydrate malabsorption 1 year after gastric bypass surgery (GBP)
    Gary Wang
    New York Obesity Nutrition Research Center, New York, NY, USA
    Obes Surg 22:1263-7. 2012
    ..The mechanisms of enhanced incretin release in response to nutrients after GBP is not elucidated and may be in relation to altered nutrient transit time and/or malabsorption...
  28. ncbi request reprint Regional subcutaneous-fat loss induced by caloric restriction in obese women
    Jack Wang
    Body Composition Unit, Obesity Research Center, Department of Medicine, St Luke s Roosevelt Hospital, Columbia University, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Obes Res 10:885-90. 2002
    ....
  29. pmc Inhibiting endogenous cortisol blunts the meal-entrained rise in serum leptin
    BLANDINE LAFERRERE
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, New York 10025, USA
    J Clin Endocrinol Metab 91:2232-8. 2006
    ..Administration of glucocorticoids increases serum leptin levels in lean and obese individuals. A morning meal produces an increase in insulin, a cortisol peak, and an increase in leptin; these changes do not occur during fasting...
  30. ncbi request reprint Physical disability and obesity
    Tsan Hon Liou
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, USA
    Nutr Rev 63:321-31. 2005
    ..Health professionals should identify disabled patients at risk and provide early prevention guidance. Research is needed to help generate detailed clinical guidelines to promote weight control among people with physical disabilities...
  31. doi request reprint The bariatric surgery patient: lost to follow-up; from morbid obesity to severe malnutrition
    Gregory B Dodell
    Division of Endocrinology, Diabetes and Nutrition, St Luke s Roosevelt Hospital Center, New York, New York 10025, USA
    Endocr Pract 18:e21-5. 2012
    ....
  32. doi request reprint Surgical weight loss: impact on energy expenditure
    David Thivel
    New York Obesity Nutrition Research Center, Department of Medicine, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Obes Surg 23:255-66. 2013
    ..Physical activity and sustained intakes of dietary protein may be the best strategies available to increase non-resting and then total energy expenditure, as well as to prevent the decline in lean mass and resting energy expenditure...
  33. pmc Short sleep duration, glucose dysregulation and hormonal regulation of appetite in men and women
    Marie Pierre St-Onge
    New York Obesity Nutrition Research Center, St Luke s Roosevelt Hospital, New York, NY, USA
    Sleep 35:1503-10. 2012
    ..To determine the hormonal effects of reducing sleep duration under controlled feeding conditions...
  34. pmc Stress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic disease
    Mousumi Bose
    New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Curr Opin Endocrinol Diabetes Obes 16:340-6. 2009
    ..This association may be mediated by alterations in the hypothalamic-pituitary-adrenal (HPA) axis. In this review, we summarize the major research that has been conducted on the role of the HPA axis in obesity and metabolic disease...
  35. pmc Limited recovery of β-cell function after gastric bypass despite clinical diabetes remission
    Roxanne Dutia
    Department of Medicine, St Luke s Roosevelt Hospital Center, New York, NY
    Diabetes 63:1214-23. 2014
    ..This impairment can be rescued by oral glucose stimulation, suggesting that RYGBP leads to an important gastrointestinal effect, critical for improved β-cell function after surgery. ..
  36. ncbi request reprint Calorie intake and meal patterns up to 4 years after Roux-en-Y gastric bypass surgery
    Joumana Wardé-Kamar
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Obes Surg 14:1070-9. 2004
    ..This study was undertaken to evaluate the caloric amount, nutrient composition and meal patterns of patients 18 months to 4 years after RYGBP. Ethnic differences in food intake were also investigated...

Research Grants7

  1. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2006
    ..As more obese diabetic patients undergo GBP, understanding the mechanisms that produce improvement in their diabetes is increasingly important. ..
  2. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE B LAFERRERE; Fiscal Year: 2010
    ..We wish to apply our findings to possible medical alternatives for the treatment of obesity and T2DM. ..
  3. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2005
    ..As more obese diabetic patients undergo GBP, understanding the mechanisms that produce improvement in their diabetes is increasingly important. ..
  4. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE B LAFERRERE; Fiscal Year: 2010
    ..We wish to apply our findings to possible medical alternatives for the treatment of obesity and T2DM. ..
  5. Mechanisms of Diabetes Control After Weight Loss Surgery
    BLANDINE LAFERRERE; Fiscal Year: 2009
    ..We wish to apply our findings to possible medical alternatives for the treatment of obesity and T2DM. ..