Louise Kuhn

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Direct visual inspection for cervical cancer screening: an analysis of factors influencing test performance
    Lynette Denny
    Department of Obstetrics and Gynecology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Cancer 94:1699-707. 2002
  2. pmc Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants?
    Louise Kuhn
    Gertrude H Sergievsky Center, Mailman School of Public Health, Columbia University, New York, NY, USA
    Clin Infect Dis 41:1654-61. 2005
  3. ncbi request reprint Intravaginal practices, bacterial vaginosis, and women's susceptibility to HIV infection: epidemiological evidence and biological mechanisms
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Lancet Infect Dis 5:786-94. 2005
  4. pmc Immune pathogenesis of pediatric HIV-1 infection
    Caroline T Tiemessen
    AIDS Virus Research Unit, National Institute for Communicable Diseases and University of the Witwatersand, Private Bag X4, Sandringham, 2131, South Africa
    Curr HIV/AIDS Rep 3:13-9. 2006
  5. pmc CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV
    Caroline T Tiemessen
    AIDS Virus Research Unit, National Institute for Communicable Diseases and University of the Witwatersand, Sandringham 2131, South Africa
    Nat Immunol 8:219-22. 2007
  6. pmc Distribution of high-risk human papillomavirus genotypes among HIV-negative women with and without cervical intraepithelial neoplasia in South Africa
    Alicia C McDonald
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e44332. 2012
  7. ncbi request reprint Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Columbia University, New York, NY 10032, USA
    Lancet Infect Dis 12:521-30. 2012
  8. pmc Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study
    Ziad El-Khatib
    Nordic School of Public Health NHV, Gothenburg, Sweden
    BMC Public Health 11:88. 2011
  9. pmc Alpha-defensins in the prevention of HIV transmission among breastfed infants
    Louise Kuhn
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 39:138-42. 2005
  10. pmc Prolonged breast-feeding and mortality up to two years post-partum among HIV-positive women in Zambia
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    AIDS 19:1677-81. 2005

Detail Information

Publications99

  1. ncbi request reprint Direct visual inspection for cervical cancer screening: an analysis of factors influencing test performance
    Lynette Denny
    Department of Obstetrics and Gynecology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Cancer 94:1699-707. 2002
    ..The authors evaluated direct visual inspection of the cervix after the application of 5% acetic acid (DVI) as a cervical cancer screening test for use in low-resource settings...
  2. pmc Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants?
    Louise Kuhn
    Gertrude H Sergievsky Center, Mailman School of Public Health, Columbia University, New York, NY, USA
    Clin Infect Dis 41:1654-61. 2005
    ..We investigated the hypothesis that the severity of HIV disease and immune dysfunction among mothers is associated with increased morbidity and mortality among their uninfected infants...
  3. ncbi request reprint Intravaginal practices, bacterial vaginosis, and women's susceptibility to HIV infection: epidemiological evidence and biological mechanisms
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Lancet Infect Dis 5:786-94. 2005
    ..Further research into factors that increase women's susceptibility to HIV will help to inform the design of vaginal microbicides and other HIV prevention interventions...
  4. pmc Immune pathogenesis of pediatric HIV-1 infection
    Caroline T Tiemessen
    AIDS Virus Research Unit, National Institute for Communicable Diseases and University of the Witwatersand, Private Bag X4, Sandringham, 2131, South Africa
    Curr HIV/AIDS Rep 3:13-9. 2006
    ..This review focuses on the key host molecules, the CC chemokine CCL3 and HLA, which have taken center stage in these new developments...
  5. pmc CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV
    Caroline T Tiemessen
    AIDS Virus Research Unit, National Institute for Communicable Diseases and University of the Witwatersand, Sandringham 2131, South Africa
    Nat Immunol 8:219-22. 2007
  6. pmc Distribution of high-risk human papillomavirus genotypes among HIV-negative women with and without cervical intraepithelial neoplasia in South Africa
    Alicia C McDonald
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e44332. 2012
    ..Here we describe the prevalence and distribution of hrHPV genotypes among HIV-negative women in South Africa, with and without cervical intraepithelial neoplasia (CIN)...
  7. ncbi request reprint Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Columbia University, New York, NY 10032, USA
    Lancet Infect Dis 12:521-30. 2012
    ..We present the long-term outcomes of switching nevirapine-exposed children to nevirapine-based treatment after effective suppression of virus replication with a protease-inhibitor-based regimen...
  8. pmc Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study
    Ziad El-Khatib
    Nordic School of Public Health NHV, Gothenburg, Sweden
    BMC Public Health 11:88. 2011
    ..We assessed risk factors for incomplete adherence among a cohort of HIV-infected women initiating ART and examined associations between adherence and virologic response to ART...
  9. pmc Alpha-defensins in the prevention of HIV transmission among breastfed infants
    Louise Kuhn
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 39:138-42. 2005
    ..3, 95% confidence interval: 0.09-0.93). Our data suggest that there may be a role for alpha-defensins in prevention of HIV transmission to breastfed infants...
  10. pmc Prolonged breast-feeding and mortality up to two years post-partum among HIV-positive women in Zambia
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    AIDS 19:1677-81. 2005
    ..A previously reported association between prolonged lactation and maternal mortality has generated concern that breast-feeding may be detrimental for HIV-positive women...
  11. pmc Survival and health benefits of breastfeeding versus artificial feeding in infants of HIV-infected women: developing versus developed world
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Clin Perinatol 37:843-62, x. 2010
    ..For most of the developing world, the health and survival benefits of breastfeeding exceed the risks of HIV transmission, especially when antiretroviral interventions are provided...
  12. doi request reprint Efficacy of human papillomavirus-based screen-and-treat for cervical cancer prevention among HIV-infected women
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    AIDS 24:2553-61. 2010
    ..Here, we evaluate the efficacy among HIV-infected women of a simpler, screen-and-treat strategy in which all women with a positive screening test are treated with cryotherapy...
  13. pmc Bystander effects: children who escape infection but not harm
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Acquir Immune Defic Syndr 46:517-8. 2007
  14. pmc HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmission
    Louise Kuhn
    Gertrude H, Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Int AIDS Soc 12:36. 2009
    ..This will lead to reduced HIV transmission and will protect the health of women without compromising the health and well-being of infants and young children...
  15. pmc Differential effects of early weaning for HIV-free survival of children born to HIV-infected mothers by severity of maternal disease
    Louise Kuhn
    Gertrude H Sergievsky Center, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    PLoS ONE 4:e6059. 2009
    ..Since early weaning was poorly accepted, we conducted a secondary analysis to investigate whether beneficial effects may have been hidden...
  16. pmc Mortality and virologic outcomes after access to antiretroviral therapy among a cohort of HIV-infected women who received single-dose nevirapine in Lusaka, Zambia
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032 3702, USA
    J Acquir Immune Defic Syndr 52:132-6. 2009
    ..We investigated mortality and virologic and clinical outcomes after introduction of antiretroviral treatment (ART) among a cohort of women given SDNVP...
  17. ncbi request reprint Synergy between mannose-binding lectin gene polymorphisms and supplementation with vitamin A influences susceptibility to HIV infection in infants born to HIV-positive mothers
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Clin Nutr 84:610-5. 2006
    ..Mannose-binding lectin (MBL-2) allele variants are associated with deficiencies in innate immunity and have been found to be correlated with HIV infection in adults and children...
  18. pmc Hiv-specific secretory IgA in breast milk of HIV-positive mothers is not associated with protection against HIV transmission among breast-fed infants
    Louise Kuhn
    Gertrude H Sergievsky Center and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Pediatr 149:611-6. 2006
    ..To test whether secretory immunoglobulin A (sIgA) to human immunodeficiency virus (HIV) antigens in breast milk of HIV-positive women is associated with protection against HIV transmission among breast-fed infants...
  19. pmc Effects of early, abrupt weaning on HIV-free survival of children in Zambia
    Louise Kuhn
    Gertrude H Sergievsky Center and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York 10032, USA
    N Engl J Med 359:130-41. 2008
    ..We conducted a randomized trial to evaluate whether abrupt weaning at 4 months as compared with the standard practice has a net benefit for HIV-free survival of children...
  20. pmc High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 2:e1363. 2007
    ..We conducted a prospective, observational study in Lusaka, Zambia, to test the hypothesis that EBF is associated with a lower risk of postnatal HIV transmission than non-EBF...
  21. ncbi request reprint Preventing mother-to-child HIV transmission in the new millennium: the challenge of breast feeding
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Paediatr Perinat Epidemiol 18:10-6. 2004
    ..Innovative approaches are needed to mobilise and train effective counsellors among health care workers and, as appropriate, community members...
  22. pmc Elevations in mortality associated with weaning persist into the second year of life among uninfected children born to HIV-infected mothers
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Departments of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
    Clin Infect Dis 50:437-44. 2010
    ..Early weaning has been recommended to reduce postnatal human immunodeficiency virus (HIV) transmission. We evaluated the safety of stopping breast-feeding at different ages for mortality of uninfected children born to HIV-infected mothers...
  23. ncbi request reprint Human immunodeficiency virus type 1 envelope-stimulated interleukin-2 production and survival of infected children with severe and mild clinical disease
    L Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Division of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    J Infect Dis 184:691-8. 2001
    ..HIV-specific cellular immune responses may play a role in containing progression of HIV-1 infection in children, despite early deficits in cell-mediated immunity...
  24. ncbi request reprint Interferon-gamma and interleukin-10 production among HIV-1-infected and uninfected infants of HIV-1-infected mothers
    L Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Division of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Pediatr Res 50:412-6. 2001
    ..Stronger relative production of IFN-gamma to IL-10 in cord blood cells from infants of HIV-1-infected mothers may be associated with protection against perinatal HIV infection...
  25. pmc Reduced HIV-stimulated T-helper cell reactivity in cord blood with short-course antiretroviral treatment for prevention of maternal-infant transmission
    L Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Division of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, USA
    Clin Exp Immunol 123:443-50. 2001
    ..Our results suggest that short-course antiretroviral treatment given to prevent maternal-infant HIV transmission may attenuate HIV-stimulated T-cell memory responses in the neonate...
  26. ncbi request reprint Human immunodeficiency virus (HIV)-specific cellular immune responses in newborns exposed to HIV in utero
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Division of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Clin Infect Dis 34:267-76. 2002
    ..Many questions remain, but much can be learned from this special population that may be informative for development of effective immunity in response to HIV vaccines...
  27. ncbi request reprint Disease progression and early viral dynamics in human immunodeficiency virus-infected children exposed to zidovudine during prenatal and perinatal periods
    L Kuhn
    Columbia University, Sergievsky Center, New York, NY 10032, USA
    J Infect Dis 182:104-11. 2000
    ..More rapid disease progression was observed among infected children exposed during pregnancy or birth to Zdv if effective multidrug therapy was not initiated...
  28. ncbi request reprint Influence of breastfeeding on cognitive outcomes at age 6-8 years: follow-up of very low birth weight infants
    Melanie M Smith
    Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
    Am J Epidemiol 158:1075-82. 2003
    ..0, 7.6) for verbal ability. Indicators of social advantage confound the association between breastfeeding and cognitive function, but careful measurement can reduce residual confounding and may clarify causal relations...
  29. ncbi request reprint Prevalence of visible disruption of cervical epithelium and cervical ectopy in African women using Depo-Provera
    L Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Contraception 59:363-7. 1999
    ....
  30. ncbi request reprint Options for prevention of HIV transmission from mother to child, with a focus on developing countries
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, and Department of Epidemiology, Joseph L Mailman School of Public Health, New York 10032, USA
    Paediatr Drugs 4:191-203. 2002
    ..A promising new line of research has recently been broached with the findings from a study in South Africa, which demonstrated that exclusive breast feeding is associated with a significant reduction in postnatal transmission of HIV...
  31. pmc Predictors of nonadherence to single-dose nevirapine therapy for the prevention of mother-to-child HIV transmission
    Sandra Albrecht
    Gertrude H Sergievsky Center, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 41:114-8. 2006
    ..Adequate adherence is required for prevention of mother-to-child transmission of HIV (pMTCT) programs to be effective. We investigated predictors and extent of nonadherence to single-dose nevirapine...
  32. pmc Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosis
    Cordula Reitz
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York 10032, USA
    J Infect Dis 201:1121-31. 2010
    ..We investigated factors associated with viral suppression and mortality among young children initiating ART...
  33. pmc Reduction in preterm delivery and neonatal mortality after the introduction of antenatal cotrimoxazole prophylaxis among HIV-infected women with low CD4 cell counts
    Jan Walter
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Infect Dis 194:1510-8. 2006
    ..We investigated whether antenatal cotrimoxazole prophylaxis begun during pregnancy for HIV-infected pregnant women with low CD4 cell counts would affect birth outcomes...
  34. pmc Growth faltering due to breastfeeding cessation in uninfected children born to HIV-infected mothers in Zambia
    Stephen Arpadi
    Columbia University Gertrude H Sergievsky Center, College of Physicians and Surgeons and Mailman School of Public Health, New York, NY 10030, USA
    Am J Clin Nutr 90:344-53. 2009
    ..The effect of breastfeeding on growth in HIV-exposed infants is not well described...
  35. pmc Low and undetectable breast milk interleukin-7 concentrations are associated with reduced risk of postnatal HIV transmission
    Jan Walter
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University New York, NY, USA
    J Acquir Immune Defic Syndr 46:200-7. 2007
    ..To investigate if breast milk interleukin [IL]-7 concentrations are associated with postnatal HIV transmission...
  36. pmc Initiation of antiretroviral therapy before 6 months of age is associated with faster growth recovery in South African children perinatally infected with human immunodeficiency virus
    Stephanie Shiau
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Pediatr 162:1138-45, 1145.e1-2. 2013
    ..To describe the effects of age at antiretroviral therapy (ART) initiation on growth outcomes among children infected with HIV followed for 48 months after treatment initiation...
  37. pmc Immune reconstitution inflammatory syndrome among HIV-infected South African infants initiating antiretroviral therapy
    Kelly Smith
    Columbia University College of Physicians and Surgeons, New York, New York, USA
    AIDS 23:1097-107. 2009
    ..To determine the incidence, clinical manifestations and risk factors for immune reconstitution inflammatory syndrome (IRIS) in young children initiating highly active antiretroviral therapy (HAART)...
  38. ncbi request reprint Maternal versus paternal inheritance of HLA class I alleles among HIV-infected children: consequences for clinical disease progression
    Louise Kuhn
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    AIDS 18:1281-9. 2004
    ..We investigated whether maternal HLA selection pressures on the virus would adversely influence clinical outcomes of HIV-infected children...
  39. doi request reprint HIV-1 concentrations in human breast milk before and after weaning
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Sci Transl Med 5:181ra51. 2013
    ..Our results support continuation of maternal antiretroviral drug interventions over the full duration of time when any breast milk exposures may occur after planned weaning...
  40. ncbi request reprint Maternal health factors and early pediatric antiretroviral therapy influence the rate of perinatal HIV-1 disease progression in children
    Elaine J Abrams
    Harlem Hospital Center and Columbia University, College of Physicians and Surgeons, New York, New York 10037, USA
    AIDS 17:867-77. 2003
    ..To determine the relationship of maternal health factors and infant antiretroviral treatment to the risk of pediatric disease progression to AIDS or death by 24 months of age...
  41. ncbi request reprint Initiation of breastfeeding among mothers of very low birth weight infants
    Melanie M Smith
    Gertrude H Sergievsky Center, New York, New York, USA
    Pediatrics 111:1337-42. 2003
    ..To examine factors that predict the initiation of expressed milk feedings and the transition to direct breastfeedings among mothers of very low birth weight (VLBW) infants...
  42. ncbi request reprint Genital herpes simplex virus infection and perinatal transmission of human immunodeficiency virus
    Katherine T Chen
    Department of Obstetrics and Gynecology, Columbia University, Sergievsky Center and Harlem Hospital Center, New York, New York 10032, USA
    Obstet Gynecol 106:1341-8. 2005
    ..To assess the risk of perinatal human immunodeficiency virus (HIV) transmission in HIV-infected women clinically diagnosed with genital herpes simplex virus (HSV) infection during pregnancy...
  43. doi request reprint A comparison of human papillomavirus testing of clinician-collected and self-collected samples during follow-up after screen-and-treat
    Sylvia Taylor
    Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Int J Cancer 129:879-86. 2011
    ..78%, p=0.01). HPV testing using self-collected vaginal specimens may be useful in primary screening but performs poorly for detecting post-treatment failures...
  44. pmc Potential impact of new WHO criteria for antiretroviral treatment for prevention of mother-to- child HIV transmission
    Louise Kuhn
    Gertrude H Sergievsky Center, Department of Epidemiology, Columbia University, New York, New York, USA
    AIDS 24:1374-7. 2010
    ..Using CD4 cell count below 350 cells/microl, irrespective of clinical stage, is more efficient and stricter CD4 cutoffs would be counter productive...
  45. pmc Early weaning increases diarrhea morbidity and mortality among uninfected children born to HIV-infected mothers in Zambia
    Ashraf Fawzy
    Columbia University, Gertrude H Sergievsky Center, College of Physicians and Surgeons and Mailman School of Public Health, New York, New York, USA
    J Infect Dis 203:1222-30. 2011
    ..Here we evaluate effects of early weaning on diarrhea morbidity and mortality of uninfected children born to HIV-infected mothers...
  46. pmc African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine
    Louise Kuhn
    Gertrude H Sergievsky Centre, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    AIDS 21:1753-61. 2007
    ..We investigated whether maternal or infant CCL3L1 gene copy numbers are associated with perinatal HIV transmission when single-dose nevirapine is given for prevention...
  47. pmc Adherence and viral suppression among infants and young children initiating protease inhibitor-based antiretroviral therapy
    Chloe A Teasdale
    ICAP Columbia University, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Pediatr Infect Dis J 32:489-94. 2013
    ....
  48. doi request reprint Metabolic abnormalities and body composition of HIV-infected children on Lopinavir or Nevirapine-based antiretroviral therapy
    Stephen Arpadi
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University Medical Center, 630 W 168th Street, New York, NY 10032, USA
    Arch Dis Child 98:258-64. 2013
    ..We compared metabolic profiles and regional fat of children on ritonavir-boosted lopinavir (lopinavir/ritonavir), lamivudine and stavudine to those switched to nevirapine, lamivudine and stavudine...
  49. doi request reprint Prenatal cocaine exposure and prolonged focus attention. Poor infant information processing ability or precocious maturation of attentional systems?
    Claudia A Chiriboga
    Division of Pediatric Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Dev Neurosci 31:149-58. 2009
    ..Whether focused attention findings impact long term development awaits further study...
  50. ncbi request reprint Breastfeeding and AIDS in the developing world
    Louise Kuhn
    Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Curr Opin Pediatr 21:83-93. 2009
    ..Data from recently completed studies provide insight into the safety and hazards of different feeding approaches as well as the use of antiretroviral therapy to prevent postnatal transmission...
  51. ncbi request reprint Factors associated with microcephaly at school age in a very-low-birthweight population
    Claudia A Chiriboga
    Division of Pediatric Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Dev Med Child Neurol 45:796-801. 2003
    ..In multivariate analyses predicting IQ at age 7 years, microcephaly was found to modify the association between neonatal lung disease and IQ...
  52. pmc Pregnancy loss and role of infant HIV status on perinatal mortality among HIV-infected women
    Hae Young Kim
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    BMC Pediatr 12:138. 2012
    ..Here we examine risk factors for these adverse pregnancy outcomes in a cohort of HIV-infected women in Zambia considering the impact of infant HIV status...
  53. doi request reprint Alternative approaches to cervical cancer screening for developing countries
    Thomas C Wright
    Department of Pathology, College of Physicians and Surgeons of Columbia University, Room 16 404, P and S Building, 630 W 168th Street, New York, NY 10032, USA
    Best Pract Res Clin Obstet Gynaecol 26:197-208. 2012
    ....
  54. pmc Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa
    Sylvia Taylor
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    BMC Med 8:40. 2010
    ..We investigated whether cervical cryotherapy reduces newly detected hrHPV infections among HIV-positive and HIV-negative women who were hrHPV negative when treated...
  55. ncbi request reprint Prenatal cocaine exposures and dose-related cocaine effects on infant tone and behavior
    Claudia A Chiriboga
    Division of Pediatric Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Neurotoxicol Teratol 29:323-30. 2007
    ..In humans, numerous studies have sought clinical correlates, but few have focused on dose-related effects, especially as regards neurologic function beyond the neonatal period...
  56. ncbi request reprint Direct comparison of liquid-based and conventional cytology in a South African screening trial
    Sylvia Taylor
    Department of Pathology, Columbia University, New York, NY 10032, USA
    Int J Cancer 118:957-62. 2006
    ..Because of the higher unit cost of LBC, low resource settings should carefully consider the potential benefits and drawbacks of LBC before adopting this new technology...
  57. pmc Human Milk Galectin-3 Binding Protein and Breast-feeding-associated HIV Transmission
    Christina S Chan
    From the Divisions of Neonatology and Pediatric Gastroenterology and Nutrition, Department of Pediatrics, University of California, San Diego, CA Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY Lusaka District Health Management Team University Teaching Hospital, University of Zambia, Lusaka, Zambia Center for International Health and Development, Boston University School of Public Health, Boston, MA and Department of Pediatrics, Children s Hospital Los Angeles, University of Southern California, Los Angeles, CA
    Pediatr Infect Dis J 32:e473-5. 2013
    ..This suggests that although milk galectin-3 binding protein is a marker of advanced maternal disease, it does not independently modify transmission risk. ..
  58. ncbi request reprint Utilisation and outcomes of cervical cancer prevention services among HIV-infected women in Cape Town
    Priya Batra
    College of Physicians and Surgeons, Columbia University, New York, NY, USA
    S Afr Med J 100:39-44. 2010
    ..An audit of outcomes of cervical cancer screening and prevention services for HIV-positive women in Cape Town, South Africa...
  59. pmc Timing of maternal HIV testing and uptake of prevention of mother-to-child transmission interventions among women and their infected infants in Johannesburg, South Africa
    Karl Günter Technau
    Empilweni Services and Research Unit, Department of Paediatrics and Child Health, Rahima Moosa Mother and Child Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa HIV Center for Clinical and Behavioral Studies, Division of Gender Sexuality and Health, Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY ICAP, Mailman School of Public Health, and Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY and Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY
    J Acquir Immune Defic Syndr 65:e170-8. 2014
    ..7%. We investigated the profile of newly diagnosed vertically infected children and their mothers to identify shortfalls in the PMTCT program...
  60. pmc Sex differences in responses to antiretroviral treatment in South African HIV-infected children on ritonavir-boosted lopinavir- and nevirapine-based treatment
    Stephanie Shiau
    Gertrude H, Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY USA
    BMC Pediatr 14:39. 2014
    ..The objective of this study was to evaluate for sex differences in response to ART in South African HIV-infected children who were randomized to continue ritonavir-boosted lopinavir (LPV/r)-based ART or switch to nevirapine-based ART...
  61. ncbi request reprint Impact of utilizing p16INK4A immunohistochemistry on estimated performance of three cervical cancer screening tests
    Qi Zhang
    Department of Pathology, Columbia University, New York, NY, USA
    Int J Cancer 120:351-6. 2007
    ..In contrast, the sensitivity of other tests, such as VIA, may be overestimated with an imperfect gold standard...
  62. ncbi request reprint Use of visual screening methods for cervical cancer screening
    Thomas C Wright
    Department of Pathology, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Obstet Gynecol Clin North Am 29:701-34. 2002
    ..In the near future we should be able to determine whether these approaches should be incorporated into routine clinical care...
  63. ncbi request reprint Estimating HIV hazard rates from cross-sectional HIV prevalence data
    Kam Fai Wong
    Department of Biostatistics, Columbia University, New York, NY, USA
    Stat Med 25:2441-9. 2006
    ..We assume further the mortality rates for HIV-positive and HIV-negative individuals are known. The method is illustrated using HIV-prevalence data collected over four years among women in Cape Town, South Africa...
  64. pmc Coverage of primary mother-to-child HIV transmission isolates by second-generation broadly neutralizing antibodies
    Kyle J Nakamura
    Department of Pediatrics, Children s Hospital of Los Angeles, Los Angeles, CA, USA
    AIDS 27:337-46. 2013
    ..To assess the neutralization potency and coverage of a panel of second-generation bNAbs, we cloned and phenotypically characterized 227 primary HIV-1 envelopes from 23 mother-to-child transmission (MTCT) pairs...
  65. pmc Antiretroviral therapy outcomes in HIV-infected children after adjusting protease inhibitor dosing during tuberculosis treatment
    Cordula Frohoff
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e17273. 2011
    ..We aimed to determine virologic and toxicity outcomes among TB/HIV co-treated children with the following modifications to their antiretroviral therapy (ART): (1) super-boosted LPV/r, (2) double-dose LPV/r or (3) ritonavir...
  66. ncbi request reprint Long-term cognitive benefits of antenatal corticosteroids for prematurely born children with cranial ultrasound abnormalities
    Ilan Arad
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Obstet Gynecol 186:818-25. 2002
    ..This study of long-term neurodevelopmental outcomes of antenatal corticosteroid exposure among preterm, very-low-birth-weight infants investigated whether the effects are differential by the presence of neonatal brain injury...
  67. ncbi request reprint Should treatment be started among all HIV-infected children and then stopped?
    Elaine J Abrams
    Columbia University, New York City NY, USA
    Lancet 362:1595-6. 2003
  68. pmc Breast feeding: A time to craft new policies
    Zena Stein
    HIV Center for Clinical and Behavioral Studies, New York Psychiatric Institute, New York, USA
    J Public Health Policy 30:300-10. 2009
    ..To be effective, implementation of any recommendations must consider individual, family, and community resources...
  69. ncbi request reprint Advances in basic science understanding of mother-to-child HIV-1 transmission
    Jan Walter
    aChildren s Hospital Los Angeles, University of Southern California, Los Angeles, California, USA bGertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
    Curr Opin HIV AIDS 3:146-50. 2008
    ..The present review summarizes and discusses studies on the mechanisms underlying mother-to-child HIV transmission published in 2006-2007...
  70. doi request reprint Antiretroviral treatment in HIV-infected infants and young children: novel issues raised by the Mississippi baby
    Stephanie Shiau
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Expert Rev Anti Infect Ther 12:307-18. 2014
    ..Here, we review research conducted before the report of the 'Mississippi baby' highlighting the important new issues that now need to be taken into consideration. ..
  71. ncbi request reprint Screen-and-treat approaches for cervical cancer prevention in low-resource settings: a randomized controlled trial
    Lynette Denny
    Department of Obstetrics and Gynaecology, University of Cape Town, Cape Town, South Africa
    JAMA 294:2173-81. 2005
    ..Non-cytology-based screen-and-treat approaches for cervical cancer prevention have been developed for low-resource settings, but few have directly addressed efficacy...
  72. ncbi request reprint Exclusive breast-feeding and HIV transmission
    Anna Coutsoudis
    AIDS 16:498-9. 2002
  73. ncbi request reprint Bacterial vaginosis and susceptibility to HIV infection in South African women: a nested case-control study
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    J Infect Dis 192:1372-80. 2005
    ..Bacterial vaginosis (BV) may increase women's susceptibility to HIV infection, but there are few prospective data...
  74. pmc Women in couples antenatal HIV counseling and testing are not more likely to report adverse social events
    Katherine Semrau
    Center for International Health and Development at the Boston University School of Public Health, Boston, Massachusetts 02118, USA
    AIDS 19:603-9. 2005
    ..Couple counseling has been promoted as a strategy to improve uptake of interventions to prevent mother-to-child HIV transmission (pMTCT) and to minimize adverse social outcomes associated with disclosure of HIV status...
  75. pmc Human immunodeficiency virus-specific CD8(+) T cells in human breast milk
    Steffanie Sabbaj
    Departments of Medicine, University of Alabama at Birmingham, 35294 2170, USA
    J Virol 76:7365-73. 2002
    ..Their presence suggests a role in limiting transmission and provides a rationale for vaccine strategies to enhance these responses...
  76. pmc Reduced mortality associated with breast-feeding-acquired HIV infection and breast-feeding among HIV-infected children in Zambia
    Matthew P Fox
    Center for International Health and Development, Boston University, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 48:90-6. 2008
    ..This study assessed whether children infected postpartum have longer survival from time of infection versus those infected during gestation or delivery...
  77. ncbi request reprint Issues in the design of a clinical trial with a behavioral intervention--the Zambia exclusive breast-feeding study
    Donald M Thea
    Center for International Health and Development, Boston University School of Public Health, 710 Albany Street, 715, Boston, MA 02118, USA
    Control Clin Trials 25:353-65. 2004
    ....
  78. pmc Detection of human immunodeficiency virus type 1 envelope peptide- stimulated T-helper cell responses and variations in the corresponding regions of viral isolates among vertically infected children
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Private Bag X4, Sandringham, 2131, Johannesburg, South Africa
    Virus Genes 28:311-8. 2004
    ..These results suggest that HIV-1 specific CD4 responses may be somewhat tolerant of viral variation, although further studies are required to fully elucidate the effect of antigenic variation on immune recognition...
  79. ncbi request reprint CD38 expression on CD8(+) T cells as a prognostic marker in vertically HIV-infected pediatric patients
    Gayle G Sherman
    Department of Haematology and Molecular Medicine, School of Pathology, South African Institute for Medical Research, Johannesburg, South Africa
    Pediatr Res 51:740-5. 2002
    ..043). These findings support the view that increased CD38 expression on CD8(+) T cells has the same prognostic significance in pediatric as in adult HIV disease...
  80. pmc Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices
    Nigel Rollins
    Africa Centre for Health and Population Studies, Mtubatuba, South Africa
    J Acquir Immune Defic Syndr 35:188-95. 2004
    ..This may inform policy, programming, and training options and may be especially valuable in the absence of conclusive data on the efficacy of the interventions to be applied during the breast-feeding period...
  81. ncbi request reprint Distinguishing the temporal association between women's intravaginal practices and risk of human immunodeficiency virus infection: a prospective study of South African women
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    Am J Epidemiol 163:552-60. 2006
    ..Intravaginal practices appear unlikely to be a cofactor in the male-to-female transmission of HIV in this setting...
  82. pmc Nevirapine resistance viral mutations after repeat use of nevirapine for prevention of perinatal HIV transmission
    Louise Kuhn
    J Acquir Immune Defic Syndr 42:260-2. 2006
  83. ncbi request reprint Prospective study of hormonal contraception and women's risk of HIV infection in South Africa
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    Int J Epidemiol 36:166-74. 2007
    ..We investigated associations between HIV incidence and use of combined oral contraceptives (COC), norethindrone enanthate (NET-EN) or depot medroxyprogesterone acetate (DMPA) in a cohort of South African women...
  84. pmc Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women
    Sharon Shalekoff
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 48:245-54. 2008
    ..017), and women who had CD4 and CD8 Gag-specific responses had significantly lower viral loads (P=0.004) and higher CCL3L1 copy number (P=0.015) than those women with only CD8 Gag-specific responses...
  85. pmc Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume
    Donald M Thea
    Center for International Health and Development at the Boston University School of Public Health, Boston, Massachusetts, USA
    AIDS 20:1539-47. 2006
    ..The effect of abrupt weaning, advocated as a safe transition from exclusive breastfeeding in HIV-exposed children, on the quantity of HIV viral load in breast milk (BMVL) is not known...
  86. pmc In vivo effects of HIV-1 exposure in the presence and absence of single-dose nevirapine on cellular plasma activation markers of infants born to HIV-1-seropositive mothers
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases and Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    J Acquir Immune Defic Syndr 42:545-53. 2006
    ....
  87. pmc Impact of chloroquine on viral load in breast milk
    Katherine Semrau
    Center for International Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
    Trop Med Int Health 11:800-3. 2006
    ..Further research is needed to determine the potential role of chloroquine in prevention of HIV transmission through breastfeeding...
  88. pmc Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Department of Virology, University of the Witwatersrand, Sandringham, Johannesburg 2131, South Africa
    J Gen Virol 87:2055-65. 2006
    ..Our findings suggest that infants who display a deficient-production phenotype of CCL3 are at increased risk of acquiring HIV-1, indicating that this chemokine in particular plays an essential role in protective immunity...
  89. ncbi request reprint Nested case-control study of cervical mucosal lesions, ectopy, and incident HIV infection among women in Cape Town, South Africa
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, South Africa
    Sex Transm Dis 33:683-7. 2006
    ..The objective of this study was to test whether cervical mucosal lesions and ectopy increase women's susceptibility to HIV infection...
  90. pmc Decay of K103N mutants in cellular DNA and plasma RNA after single-dose nevirapine to reduce mother-to-child HIV transmission
    Shayne Loubser
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS 20:995-1002. 2006
    ..As this may influence subsequent treatment responses, a better understanding of the dynamics of decay and persistence of this variant is needed...
  91. pmc Re: HIV-1 disease progression in breast-feeding and formula-feeding mothers: a prospective 2-year comparison of T cell subsets, HIV-1 RNA levels, and mortality
    Louise Kuhn
    J Infect Dis 195:1728-9; author reply 1729-30. 2007
  92. pmc Temporal and lateral dynamics of HIV shedding and elevated sodium in breast milk among HIV-positive mothers during the first 4 months of breast-feeding
    Katherine Semrau
    Center for International Health and Development at the Boston University School of Public Health, Boston, Massachusetts, USA
    J Acquir Immune Defic Syndr 47:320-8. 2008
    ..To better understand the dynamics of breast milk HIV shedding and its relation to postnatal HIV transmission, we investigated the temporal and lateral relations of breast milk viral shedding and sodium concentrations in HIV-positive women...
  93. ncbi request reprint Recurrence of symptomatic bacterial vaginosis 12 months after oral metronidazole therapy in HIV-positive and -negative women
    Landon Myer
    J Infect Dis 194:1797-9. 2006
  94. pmc Low maternal viral loads and reduced granulocyte-macrophage colony-stimulating factor levels characterize exposed, uninfected infants who develop protective human immunodeficiency virus type 1-specific responses
    Diana B Schramm
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Department of Virology, University of the Witwatersrand, Gauteng, South Africa
    Clin Vaccine Immunol 14:348-54. 2007
    ....
  95. pmc Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome
    Stephen Meddows-Taylor
    AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology, University of the Witwatersrand, Johannesburg, South Africa
    J Virol Methods 144:115-21. 2007
    ....
  96. ncbi request reprint Intravaginal practices, HIV and other sexually transmitted diseases among South African women
    Landon Myer
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Sex Transm Dis 31:174-9. 2004
    ..However, data on the prevalence of these practices, and associations with HIV and other sexually transmitted diseases (STD), are limited...
  97. ncbi request reprint Cervical cancer prevention - a paradigm shift?
    Lynnette Denny
    University of Cape Town, Groote Schuur Hospital, H 45, Old Main Building, Observatory 7925, South Africa
    Gynecol Oncol 99:S12. 2005
  98. pmc The mucosae-associated epithelial chemokine (MEC/CCL28) modulates immunity in HIV infection
    Eleonora Castelletti
    Department of Preclinical Sciences, Laboratorio Interdisciplinare Technologie Avanzate Vialba, University of Milano, Milano, Italy
    PLoS ONE 2:e969. 2007
    ..The CCL28 circuit was analyzed in HIV-infected and-exposed individuals and in HIV-unexposed controls; the effect of CCL28 administration on gastrointestinal MLP IgA-ASC was verified in a mouse model...

Research Grants35

  1. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2001
    ..In addition, we will evaluate the associations between manganese, organic solvents and ET using a lifetime Occupational History. ..
  2. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2007
    ..Knowledge of the pathological changes and neurochemical abnormality in ET is critical for the design of new therapies for ET. ..
  3. Safer Weaning Practices for HIV-infected women
    Louise Kuhn; Fiscal Year: 2007
    ..Our goal is to develop evidence-based nutrition counseling messages about safer practices for HIV-infected women and their infants around the time of weaning. ..
  4. Safer Weaning Practices for HIV-infected women
    Louise Kuhn; Fiscal Year: 2009
    ..Our goal is to develop evidence-based nutrition counseling messages about safer practices for HIV-infected women and their infants around the time of weaning. ..
  5. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2009
    ..This is a five-year competitive renewal in which we propose to firmly establish the links between this neurotoxin and ET. ..
  6. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2009
    ..Our tissue-based research will place us in unique a position to begin to address basic mechanistic questions about ET and may allow treating physicians to predict during life which subtype of ET a patient is likely to have. ..
  7. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan D Louis; Fiscal Year: 2010
    ..This is a five-year competitive renewal in which we propose to firmly establish the links between this neurotoxin and ET. ..
  8. Safer Weaning Practices for HIV-infected women
    Louise Kuhn; Fiscal Year: 2010
    ..Our goal is to develop evidence-based nutrition counseling messages about safer practices for HIV-infected women and their infants around the time of weaning. ..
  9. Treatment Options for Protease Inhibitor Exposed Children
    Louise Kuhn; Fiscal Year: 2010
    ....
  10. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan D Louis; Fiscal Year: 2010
    ..Our tissue-based research will place us in unique a position to begin to address basic mechanistic questions about ET and may allow treating physicians to predict during life which subtype of ET a patient is likely to have. ..
  11. Oral Transmission of HIV through Breastfeeding
    LOUISE contact KUHN; Fiscal Year: 2010
    ..We will evaluate the role of these factors in reducing oral transmission via breastfeeding, preventing mucosal viral shedding and delaying disease progression in infected breast-fed infants. ..
  12. Clinical Relevance of Transient Nevirapine Resistance
    Louise Kuhn; Fiscal Year: 2007
    ....
  13. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2007
    ..Identification and understanding these toxicants is the first step in preventing a disease with only limited treatment options. ..
  14. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2006
    ..Knowledge of the pathological changes and neurochemical abnormality in ET is critical for the design of new therapies for ET. ..
  15. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2002
    ..In addition, we will evaluate the associations between manganese, organic solvents and ET using a lifetime Occupational History. ..
  16. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2002
    ..abstract_text> ..
  17. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2003
    ..In addition, we will evaluate the associations between manganese, organic solvents and ET using a lifetime Occupational History. ..
  18. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2003
    ..abstract_text> ..
  19. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2003
    ..Knowledge of the pathological changes and neurochemical abnormality in ET is critical for the design of new therapies for ET. ..
  20. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2004
    ..abstract_text> ..
  21. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2004
    ..Knowledge of the pathological changes and neurochemical abnormality in ET is critical for the design of new therapies for ET. ..
  22. Clinical Relevance of Transient Nevirapine Resistance
    Louise Kuhn; Fiscal Year: 2004
    ....
  23. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2005
    ..Identification and understanding these toxicants is the first step in preventing a disease with only limited treatment options. ..
  24. Pathogenesis Of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2005
    ..Knowledge of the pathological changes and neurochemical abnormality in ET is critical for the design of new therapies for ET. ..
  25. Clinical Relevance of Transient Nevirapine Resistance
    Louise Kuhn; Fiscal Year: 2005
    ....
  26. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2005
    ..abstract_text> ..
  27. ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMOR
    Elan Louis; Fiscal Year: 2006
    ..Identification and understanding these toxicants is the first step in preventing a disease with only limited treatment options. ..
  28. Clinical Relevance of Transient Nevirapine Resistance
    Louise Kuhn; Fiscal Year: 2006
    ....
  29. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2006
    ..abstract_text> ..
  30. Treatment Options for Protease Inhibitor Exposed Children
    Louise Kuhn; Fiscal Year: 2010
    ....