J A Knowles

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Results of a genome-wide genetic screen for panic disorder
    J A Knowles
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Am J Med Genet 81:139-47. 1998
  2. ncbi request reprint Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder
    R Goedken
    Department of Psychiatry, The University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
    Am J Med Genet 96:781-3. 2000
  3. ncbi request reprint No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder
    S P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, USA
    Mol Psychiatry 6:59-65. 2001
  4. ncbi request reprint Potential panic disorder syndrome: clinical and genetic linkage evidence
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University, New York, New York, USA
    Am J Med Genet 96:24-35. 2000
  5. doi request reprint Genome-wide association study of recurrent early-onset major depressive disorder
    J Shi
    Department of Psychiatry, Stanford University, Stanford, CA, USA
    Mol Psychiatry 16:193-201. 2011
  6. ncbi request reprint Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta
    L N Lawton
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Gene 203:17-26. 1997
  7. ncbi request reprint Investigation of serotonin-related genes in antidepressant response
    E J Peters
    Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
    Mol Psychiatry 9:879-89. 2004
  8. pmc Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
    Z Deng
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, New York, NY, USA
    Am J Hum Genet 67:737-44. 2000
  9. ncbi request reprint TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa
    P Banerjee
    Department of Genetics and Development, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Nat Genet 18:177-9. 1998
  10. ncbi request reprint High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p
    S Ranta
    Department of Psychiatry, Columbia Genome Center, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Genome Res 7:887-96. 1997

Research Grants

  1. GENETIC RISK FACTORS FOR NICOTINE ADDICTION
    Alexander Glassman; Fiscal Year: 2004

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Results of a genome-wide genetic screen for panic disorder
    J A Knowles
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Am J Med Genet 81:139-47. 1998
    ..Analysis with SIBPAIR yielded P values equivalent to a lod score of 1.0 or greater (i.e., P < .016, one-sided, uncorrected for multiple tests) for 11 marker loci (2, 7p, 8p, 8q, 9p, 11q, 12q, 16p, 20p and 20q)...
  2. ncbi request reprint Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder
    R Goedken
    Department of Psychiatry, The University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
    Am J Med Genet 96:781-3. 2000
    ..Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781-783, 2000...
  3. ncbi request reprint No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder
    S P Hamilton
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, USA
    Mol Psychiatry 6:59-65. 2001
    ..The results reported here provide little support for the role of these polymorphisms in panic disorder...
  4. ncbi request reprint Potential panic disorder syndrome: clinical and genetic linkage evidence
    M M Weissman
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University, New York, New York, USA
    Am J Med Genet 96:24-35. 2000
    ..Am. J. Med. Genet.(Neuropsychiatr. Genet.) 96:24-35, 2000...
  5. doi request reprint Genome-wide association study of recurrent early-onset major depressive disorder
    J Shi
    Department of Psychiatry, Stanford University, Stanford, CA, USA
    Mol Psychiatry 16:193-201. 2011
    ..Larger samples will be required to confirm the hypothesis of association between MDD (and particularly the recurrent early-onset subtype) and common SNPs...
  6. ncbi request reprint Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta
    L N Lawton
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Gene 203:17-26. 1997
    ..9 kb that is predominant in adult skeletal muscle. Most importantly, the 1.2-kb PTGFB transcript was shown to be expressed in placenta at much higher levels than in any other human fetal or adult tissue surveyed...
  7. ncbi request reprint Investigation of serotonin-related genes in antidepressant response
    E J Peters
    Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
    Mol Psychiatry 9:879-89. 2004
    ..Intriguingly, we observe that a number of the less frequent alleles of many of the SNP markers were associated with the nonresponse and nonspecific phenotypes...
  8. pmc Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
    Z Deng
    Department of Psychiatry, College of Physicians and Surgeons at Columbia University and the New York State Psychiatric Institute, New York, NY, USA
    Am J Hum Genet 67:737-44. 2000
    ..These findings indicate that the bone morphogenetic protein-signaling pathway is defective in patients with primary pulmonary hypertension and may implicate the pathway in the nonfamilial forms of the disease...
  9. ncbi request reprint TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa
    P Banerjee
    Department of Genetics and Development, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Nat Genet 18:177-9. 1998
    ..The mutation was not observed in 210 unrelated controls. The data indicate that impairment of TULP1 protein function is a rare cause of arRP and that the normal protein plays an essential role in the physiology of the retina...
  10. ncbi request reprint High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p
    S Ranta
    Department of Psychiatry, Columbia Genome Center, College of Physicians and Surgeons at Columbia University and New York State Psychiatric Institute, New York 10032, USA
    Genome Res 7:887-96. 1997
    ..Several partial gene sequences have been identified from the region and are being analyzed as candidate genes for EPMR...

Research Grants1

  1. GENETIC RISK FACTORS FOR NICOTINE ADDICTION
    Alexander Glassman; Fiscal Year: 2004
    ..Detecting these genes would be a significant first step in our understanding of the genetic variation of addiction to nicotine and possibly other drugs of abuse. ..