Alexander D Klose

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Fluorescence tomography with simulated data based on the equation of radiative transfer
    Alexander D Klose
    Department of Biomedical Engineering and Radiology, Columbia University, ET351 Mudd Building, MC 8904, 500 West 120th Street, New York, New York 10027, USA
    Opt Lett 28:1019-21. 2003
  2. pmc In vivo bioluminescence tomography with a blocking-off finite-difference SP3 method and MRI/CT coregistration
    Alexander D Klose
    Columbia University, New York, New York 10027, USA
    Med Phys 37:329-38. 2010
  3. doi request reprint Bioluminescence tomography with CT/MRI co-registration
    A D Klose
    Department of Radiology at Columbia University, New York, NY 10027, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6327-30. 2009
  4. pmc Hyperspectral excitation-resolved fluorescence tomography of quantum dots
    Alexander D Klose
    Department of Radiology, Columbia University, ET351 Mudd Building, MC 8904, 500 West 120th Street, New York, New York 10027, USA
    Opt Lett 34:2477-9. 2009
  5. pmc Excitation-resolved fluorescence tomography with simplified spherical harmonics equations
    Alexander D Klose
    Department of Radiology, Columbia University Medical Center, New York, NY 10032, USA
    Phys Med Biol 56:1443-69. 2011
  6. ncbi request reprint Transport-theory-based stochastic image reconstruction of bioluminescent sources
    Alexander D Klose
    Department of Radiology, Columbia University, New York, NY 10027, USA
    J Opt Soc Am A Opt Image Sci Vis 24:1601-8. 2007
  7. pmc Registration of planar bioluminescence to magnetic resonance and x-ray computed tomography images as a platform for the development of bioluminescence tomography reconstruction algorithms
    Bradley J Beattie
    Memorial Sloan Kettering Cancer Center, Department of Neurology, 1275 York Avenue, New York, New York 10065, USA
    J Biomed Opt 14:024045. 2009
  8. doi request reprint Multiparameter classifications of optical tomographic images
    Christian D Klose
    Columbia University, Department of Biomedical Engineering, New York, New York 10027, USA
    J Biomed Opt 13:050503. 2008
  9. pmc Computer-aided interpretation approach for optical tomographic images
    Christian D Klose
    Columbia University, Department of Biomedical Engineering, New York, NY 10027, USA
    J Biomed Opt 15:066020. 2010
  10. ncbi request reprint Sagittal laser optical tomography for imaging of rheumatoid finger joints
    Andreas H Hielscher
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Phys Med Biol 49:1147-63. 2004

Detail Information

Publications11

  1. ncbi request reprint Fluorescence tomography with simulated data based on the equation of radiative transfer
    Alexander D Klose
    Department of Biomedical Engineering and Radiology, Columbia University, ET351 Mudd Building, MC 8904, 500 West 120th Street, New York, New York 10027, USA
    Opt Lett 28:1019-21. 2003
    ..We obtain images of either the quantum yield or the fluorophore absorption...
  2. pmc In vivo bioluminescence tomography with a blocking-off finite-difference SP3 method and MRI/CT coregistration
    Alexander D Klose
    Columbia University, New York, New York 10027, USA
    Med Phys 37:329-38. 2010
    ..Therefore, the authors have developed a linear image reconstruction method for bioluminescence tomography (BLT) that recovers the three-dimensional spatial bioluminescent source distribution in small animals...
  3. doi request reprint Bioluminescence tomography with CT/MRI co-registration
    A D Klose
    Department of Radiology at Columbia University, New York, NY 10027, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6327-30. 2009
    ..We present in vivo bioluminescence reconstruction results that demonstrate the performance of our co-registration method...
  4. pmc Hyperspectral excitation-resolved fluorescence tomography of quantum dots
    Alexander D Klose
    Department of Radiology, Columbia University, ET351 Mudd Building, MC 8904, 500 West 120th Street, New York, New York 10027, USA
    Opt Lett 34:2477-9. 2009
    ..Numerical results suggest that current planar surface imaging technology could easily be retrofitted for performing fluorescence tomography without the use of elaborate source-detector multiplexing...
  5. pmc Excitation-resolved fluorescence tomography with simplified spherical harmonics equations
    Alexander D Klose
    Department of Radiology, Columbia University Medical Center, New York, NY 10032, USA
    Phys Med Biol 56:1443-69. 2011
    ....
  6. ncbi request reprint Transport-theory-based stochastic image reconstruction of bioluminescent sources
    Alexander D Klose
    Department of Radiology, Columbia University, New York, NY 10027, USA
    J Opt Soc Am A Opt Image Sci Vis 24:1601-8. 2007
    ..Numerical experiments demonstrate the feasibility of reconstructing bioluminescent source distributions in tissuelike media...
  7. pmc Registration of planar bioluminescence to magnetic resonance and x-ray computed tomography images as a platform for the development of bioluminescence tomography reconstruction algorithms
    Bradley J Beattie
    Memorial Sloan Kettering Cancer Center, Department of Neurology, 1275 York Avenue, New York, New York 10065, USA
    J Biomed Opt 14:024045. 2009
    ..36+/-0.23 mm. Additional experiments highlight some of the confounds that are often overlooked in the BLT reconstruction process, and for two of these confounds, simple corrections are proposed...
  8. doi request reprint Multiparameter classifications of optical tomographic images
    Christian D Klose
    Columbia University, Department of Biomedical Engineering, New York, New York 10027, USA
    J Biomed Opt 13:050503. 2008
    ..54, and an area under the curve (AUC) of 0.72. These values are higher than for previously reported single parameter classifications with a best sensitivity and specificity of 0.71, a Youden index of 0.41, and an AUC of 0.66...
  9. pmc Computer-aided interpretation approach for optical tomographic images
    Christian D Klose
    Columbia University, Department of Biomedical Engineering, New York, NY 10027, USA
    J Biomed Opt 15:066020. 2010
    ..9 can be achieved. These values are much higher than values obtained when only single parameter classifications were used, where sensitivities and specificities remained well below 0.8...
  10. ncbi request reprint Sagittal laser optical tomography for imaging of rheumatoid finger joints
    Andreas H Hielscher
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Phys Med Biol 49:1147-63. 2004
    ..We have used this system to obtain tomographic images of six proximal interphalangeal finger joints from two patients with rheumatoid arthritis. The optical images were compared to clinical symptoms and ultrasound images...
  11. ncbi request reprint Comparison of two and three-dimensional optical tomographic image reconstructions of human finger joints
    Rong Song
    Depts of Biomedical Engineering and Radiology at Columbia University, New York, NY 10027 USA
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..In particular we examined how these different approaches affect the discrimination between healthy and RA joints...