JAN K KITAJEWSKI

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis
    Sonia L Hernandez
    Department of Pediatrics, Columbia University Medical Center, New York, NY, USA
    Vasc Cell 5:17. 2013
  2. pmc Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis
    C V Reeves
    Columbia University Medical Center, New York, NY 10035, USA
    Oncogene 29:789-801. 2010
  3. pmc Anthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activity
    Claire V Reeves
    Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York, United States of America
    PLoS ONE 7:e34862. 2012
  4. pmc Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4)
    Vuk P Jovanovic
    Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th Street, New York, NY 10032, USA
    Reprod Biol Endocrinol 11:43. 2013
  5. pmc Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis
    Claire Reeves
    Department of Ob Gyn, Columbia University Medical Center, New York, NY 10032, USA
    Toxins (Basel) 5:315-26. 2013
  6. pmc "Large eaters" meet blood vessels: a new thematic series on macrophages and angiogenesis
    Jan Kitajewski
    Pathology, Ob Gyn, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St, Nicholas Ave, NY, NY, 10032, USA
    Vasc Cell 4:17. 2012
  7. pmc Expression of HES and HEY genes in infantile hemangiomas
    Omotinuwe Adepoju
    Department of Surgery, College of Physicians and Surgeons, 630 W168th St, New York, 10032, USA
    Vasc Cell 3:19. 2011
  8. pmc Fine-tuning endothelial Notch: SIRT-ainly an unexpected mechanism
    Jan Kitajewski
    Department of Ob Gyn, Pathology, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA
    Dev Cell 20:577-8. 2011
  9. pmc Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity
    Yasuhiro Funahashi
    Pathology and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, NY, NY 10032, USA
    Vasc Cell 3:2. 2011
  10. pmc Chloride intracellular channel 1 functions in endothelial cell growth and migration
    Jennifer J Tung
    Department of Obstetrics Gynecology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St, Nicholas Ave, 926, New York, NY 10032, USA
    J Angiogenes Res 2:23. 2010

Collaborators

  • Joy Y Vink
  • June K Wu
  • Dimitris Anastassiou
  • Carrie J Shawber
  • Yasuhiro Funahashi
  • Alvin Wong
  • Vuk P Jovanovic
  • Claire Reeves
  • Sonia L Hernandez
  • Xing Wang
  • Claire V Reeves
  • Omotinuwe Adepoju
  • Anshula Sharma
  • C V Reeves
  • Jennifer J Tung
  • Alejandro Garcia
  • Angela Kadenhe-Chiweshe
  • Debarshi Banerjee
  • Raul Gomez
  • Pelisa Charles-Horvath
  • Thaned Kangsamaksin
  • Christopher M Sauer
  • Mark V Sauer
  • Jessica J Kandel
  • Darrell J Yamashiro
  • Wei yi Cheng
  • Ralf C Zimmermann
  • Pelisa C Charles-Horvath
  • John A T Young
  • Alex M Kitajewski
  • Krista L Hardy
  • Valeriya Y Borisenko
  • Alex Kitajewski
  • Karen Tong
  • Yun K Choi
  • Emi Kanamaru
  • Joyce Bischoff
  • Elisa Boscolo
  • Marina Vorontchikhina
  • Hasina H Outtz
  • J Dufraine
  • J A T Young

Detail Information

Publications15

  1. pmc Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis
    Sonia L Hernandez
    Department of Pediatrics, Columbia University Medical Center, New York, NY, USA
    Vasc Cell 5:17. 2013
    ....
  2. pmc Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis
    C V Reeves
    Columbia University Medical Center, New York, NY 10035, USA
    Oncogene 29:789-801. 2010
    ..We conclude that ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds...
  3. pmc Anthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activity
    Claire V Reeves
    Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York, United States of America
    PLoS ONE 7:e34862. 2012
    ..We identified an ANTXR2/MT1-MMP complex and demonstrated that MT1-MMP activity is dependent on ANTXR2 expression levels in cells. Thus, we have discovered that ANTXR1 and ANTXR2 function as positive regulators of MT1-MMP activity...
  4. pmc Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4)
    Vuk P Jovanovic
    Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th Street, New York, NY 10032, USA
    Reprod Biol Endocrinol 11:43. 2013
    ..We hypothesized that blocking Notch pathways would disrupt follicular maturation in the mouse ovary...
  5. pmc Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis
    Claire Reeves
    Department of Ob Gyn, Columbia University Medical Center, New York, NY 10032, USA
    Toxins (Basel) 5:315-26. 2013
    ..Mice mutant in Antxr genes have defects in extracellular matrix homeostasis. We discuss how knowledge of physiological ANTXR function relates to what is already known about anthrax intoxication...
  6. pmc "Large eaters" meet blood vessels: a new thematic series on macrophages and angiogenesis
    Jan Kitajewski
    Pathology, Ob Gyn, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St, Nicholas Ave, NY, NY, 10032, USA
    Vasc Cell 4:17. 2012
    ..ABSTRACT: Vascular Cell has launched a new series on macrophages and angiogenesis, a quickly evolving field critical to blood and lymphatic vessels during development, inflammation and tumorigenesis...
  7. pmc Expression of HES and HEY genes in infantile hemangiomas
    Omotinuwe Adepoju
    Department of Surgery, College of Physicians and Surgeons, 630 W168th St, New York, 10032, USA
    Vasc Cell 3:19. 2011
    ..abstract:..
  8. pmc Fine-tuning endothelial Notch: SIRT-ainly an unexpected mechanism
    Jan Kitajewski
    Department of Ob Gyn, Pathology, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA
    Dev Cell 20:577-8. 2011
    ..This regulation is critical for vascular sprouting and raises intriguing questions about therapeutic targeting of SIRT1 in angiogenesis and the potential mechanisms that link vascular growth and energy homeostasis...
  9. pmc Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity
    Yasuhiro Funahashi
    Pathology and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, NY, NY 10032, USA
    Vasc Cell 3:2. 2011
    ..abstract:..
  10. pmc Chloride intracellular channel 1 functions in endothelial cell growth and migration
    Jennifer J Tung
    Department of Obstetrics Gynecology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, 1130 St, Nicholas Ave, 926, New York, NY 10032, USA
    J Angiogenes Res 2:23. 2010
    ..Little is known about the role of CLIC1 in endothelium. These studies investigate CLIC1 as a regulator of angiogenesis by in vitro techniques that mimic individual steps in the angiogenic process...
  11. pmc Notch regulates the angiogenic response via induction of VEGFR-1
    Yasuhiro Funahashi
    Pathology, Obstetrics and Gynecology, and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA
    J Angiogenes Res 2:3. 2010
    ..In summary, we show that Notch1 plays a role in endothelial cells by regulating VEGFR-1, a function that may be important for physiological and pathological angiogenesis...
  12. pmc A potential role for notch signaling in the pathogenesis and regulation of hemangiomas
    June K Wu
    Departments of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Craniofac Surg 20:698-702. 2009
    ..These findings support a role for Notch in hemangiomas, meriting further analysis of the functional relevance of Notch signaling in hemangiomas...
  13. pmc Propranolol accelerates adipogenesis in hemangioma stem cells and causes apoptosis of hemangioma endothelial cells
    Alvin Wong
    Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Plast Reconstr Surg 130:1012-21. 2012
    ..The authors hypothesize that propranolol facilitates their involution by altering cellular behavior in both hemangioma endothelial and stem cells...