Krzysztof Kiryluk

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis
    Krzysztof Kiryluk
    Division of Nephrology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 80:79-87. 2011
  2. pmc Pathogenesis of immunoglobulin A nephropathy: recent insight from genetic studies
    Krzysztof Kiryluk
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Annu Rev Med 64:339-56. 2013
  3. doi request reprint Renal function and genetic variation in dopamine D(1) receptor: is the case strong enough?
    Krzysztof Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 76:1019-22. 2009
  4. doi request reprint Quantitative genetics of renal function: tackling complexities of the eGFR phenotype in gene mapping studies
    Krzysztof Kiryluk
    Columbia University, Department of Medicine, Division of Nephrology, New York, New York 10033, USA
    Kidney Int 74:1109-12. 2008
  5. doi request reprint A young man with Propionibacterium acnes-induced shunt nephritis
    K Kiryluk
    Department of Medicine, Division of Nephrology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 73:1434-40. 2008
  6. doi request reprint The Case: Thirty-one-year old woman with hypertension and abnormal renal imaging
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 73:659-60. 2008
  7. doi request reprint Acute chorea and bilateral basal ganglia lesions in a hemodialysis patient
    K Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 73:1087-91. 2008
  8. ncbi request reprint Minimally invasive treatment of bilateral ureteropelvic obstruction with massive calculi
    K Kiryluk
    Division of Nephrology, Department of Medicine, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA
    Kidney Int 73:134-5. 2008
  9. ncbi request reprint Thiazolidinediones and fluid retention
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10033, USA
    Kidney Int 72:762-8. 2007
  10. ncbi request reprint White star in the black sea: an unusual stone associated with ureteropelvic junction obstruction
    K Kiryluk
    Department of Medicine, Division of Nephrology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 71:1330. 2007

Collaborators

Detail Information

Publications24

  1. pmc Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis
    Krzysztof Kiryluk
    Division of Nephrology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 80:79-87. 2011
    ..Thus, serum galactose-deficient IgA1 levels are highly inherited in pediatric patients with IgAN and HSPN, providing support for another shared pathogenic link between these disorders...
  2. pmc Pathogenesis of immunoglobulin A nephropathy: recent insight from genetic studies
    Krzysztof Kiryluk
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Annu Rev Med 64:339-56. 2013
    ..Incorporating genetic, immunologic, and biochemical data, we present a multistep pathogenesis model that provides testable hypotheses for dissecting the mechanisms of disease...
  3. doi request reprint Renal function and genetic variation in dopamine D(1) receptor: is the case strong enough?
    Krzysztof Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 76:1019-22. 2009
    ..Although the study does not confirm an association with blood pressure, it suggests a new link between a common variant in the 5'-untranslated region of the DRD1 gene and low glomerular filtration rate...
  4. doi request reprint Quantitative genetics of renal function: tackling complexities of the eGFR phenotype in gene mapping studies
    Krzysztof Kiryluk
    Columbia University, Department of Medicine, Division of Nephrology, New York, New York 10033, USA
    Kidney Int 74:1109-12. 2008
    ..Mottl and colleagues attempt to tackle this problem in their analysis of a unique family-based cohort of American Indians...
  5. doi request reprint A young man with Propionibacterium acnes-induced shunt nephritis
    K Kiryluk
    Department of Medicine, Division of Nephrology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 73:1434-40. 2008
  6. doi request reprint The Case: Thirty-one-year old woman with hypertension and abnormal renal imaging
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 73:659-60. 2008
  7. doi request reprint Acute chorea and bilateral basal ganglia lesions in a hemodialysis patient
    K Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Kidney Int 73:1087-91. 2008
  8. ncbi request reprint Minimally invasive treatment of bilateral ureteropelvic obstruction with massive calculi
    K Kiryluk
    Division of Nephrology, Department of Medicine, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA
    Kidney Int 73:134-5. 2008
  9. ncbi request reprint Thiazolidinediones and fluid retention
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10033, USA
    Kidney Int 72:762-8. 2007
  10. ncbi request reprint White star in the black sea: an unusual stone associated with ureteropelvic junction obstruction
    K Kiryluk
    Department of Medicine, Division of Nephrology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 71:1330. 2007
  11. ncbi request reprint A large obstructive parapelvic cyst: challenging diagnosis and management
    K Kiryluk
    Department of Medicine, Division of Nephrology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Kidney Int 71:955. 2007
  12. ncbi request reprint Sickle cell trait and gross hematuria
    K Kiryluk
    Division of Nephrology, Department of Medicine, Columbia University, New York, New York, USA
    Kidney Int 71:706-10. 2007
  13. pmc Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis
    Krzysztof Kiryluk
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS Genet 8:e1002765. 2012
    ..These findings inform genetic, biological, and epidemiological investigations of IgAN and permit cross-comparison with other complex traits that share genetic risk loci and geographic patterns with IgAN...
  14. pmc Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression
    Natalia Papeta
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Invest 119:1178-88. 2009
    ....
  15. pmc Genetic studies of IgA nephropathy: past, present, and future
    Krzysztof Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, 1150 St Nicholas Avenue, Russ Berrie Pavilion 413, New York, NY 10032, USA
    Pediatr Nephrol 25:2257-68. 2010
    ..New genomic approaches, including genome-wide association studies currently under way, offer promising tools for elucidating the genetic basis of IgAN...
  16. pmc Genome-wide association study identifies susceptibility loci for IgA nephropathy
    Ali G Gharavi
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Nat Genet 43:321-7. 2011
    ....
  17. pmc Identification of a potential susceptibility locus for macular telangiectasia type 2
    Nancy L Parmalee
    Department of Ophthalmology, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e24268. 2012
    ..32 (rs1579634; 219.96 cM) to 229.92 Mb (rs7542797; 235.07 cM), encompassing the 1q41-42 linkage peak. Sanger sequencing of the top 14 positional candidates genes under the linkage peak revealed no causal variants in these pedigrees...
  18. pmc APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy
    Natalia Papeta
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Am Soc Nephrol 22:1991-6. 2011
    ..These data further support the strong association of genetic variants in APOL1 with susceptibility to FSGS and HIVAN among African Americans...
  19. pmc Copy-number disorders are a common cause of congenital kidney malformations
    Simone Sanna-Cherchi
    Division of Nephrology, Columbia University, New York, NY 10023, USA
    Am J Hum Genet 91:987-97. 2012
    ..A search for pathogenic CNVs should be considered in this population for the diagnosis of their specific genomic disorders and for the evaluation of the potential for developmental delay...
  20. doi request reprint The molecular pathogenesis of HIV-1 associated nephropathy: recent advances
    Natalia Papeta
    Department of Medicine, Columbia University College of Physicians and Surgeons, 1150 St Nicholas Ave, New York, NY 10032, USA
    J Mol Med (Berl) 89:429-36. 2011
    ..These findings present a framework for identification of podocyte transregulators and reconstruction of the molecular networks connecting susceptibility genes to the development of nephropathy...
  21. doi request reprint The genetics of albuminuria: from haplotype association mapping in mice to genetic causation in humans
    Roel Sterken
    Division of Nephrology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Kidney Int 77:173-5. 2010
    ..present the results of the first HAM for age-related kidney damage in mice and examine the detected loci in the context of the human genome-wide association study for diabetic nephropathy...
  22. ncbi request reprint Genetic susceptibility, HIV infection, and the kidney
    Krzysztof Kiryluk
    Department of Medicine, Division of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Clin J Am Soc Nephrol 2:S25-35. 2007
    ....
  23. doi request reprint Coiled versus straight peritoneal dialysis catheters: a randomized controlled trial and meta-analysis
    Jingyuan Xie
    Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China
    Am J Kidney Dis 58:946-55. 2011
    ..The relative benefits of these designs have not been studied adequately. The objective of this study is to compare the clinical outcomes of coiled- versus straight-end swan neck peritoneal dialysis catheters...
  24. ncbi request reprint Acute renal failure outcomes in children and adults
    J Radhakrishnan
    Department of Medicine Nephrology, Columbia University, New York 10032, USA
    Kidney Int 69:17-9. 2006
    ..Most reports have detailed the in-hospital outcomes in ARF patients. This commentary focuses on the outcomes (including quality of life) of ARF patients, both adults and children, after discharge from the hospital...